(66 nodes) Ribosomal large subunit biogenesis network (Phycomyces blakesleeanus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	A0A167PWY0	Ribosomal_L23eN domain-containing protein; Belongs to the universal ribosomal protein uL23 family. (148 aa)
	A0A167PSM1	Exonuclease domain-containing protein. (169 aa)
	A0A167PRB8	Uncharacterized protein. (108 aa)
	A0A167PIK6	Uncharacterized protein. (249 aa)
	A0A167PH19	60S ribosome subunit biogenesis protein NIP7; Required for proper 27S pre-rRNA processing and 60S ribosome subunit assembly; Belongs to the NIP7 family. (180 aa)
	A0A167PAF3	Ribosomal_L18_c domain-containing protein. (286 aa)
	A0A167P1W3	Ribosome assembly factor mrt4; Component of the ribosome assembly machinery. Nuclear paralog of the ribosomal protein P0, it binds pre-60S subunits at an early stage of assembly in the nucleolus, and is replaced by P0 in cytoplasmic pre-60S subunits and mature 80S ribosomes. (223 aa)
	A0A167NXF4	HIT-type domain-containing protein. (142 aa)
	A0A167NMK6	Ribonucloprotein; Common component of the spliceosome and rRNA processing machinery; Belongs to the eukaryotic ribosomal protein eL8 family. (163 aa)
	A0A167N6I0	RRP14 domain-containing protein. (338 aa)
	A0A167N5B1	Ribosomal_L16 domain-containing protein. (216 aa)
	A0A167N1N9	Ribosomal_L18_c domain-containing protein. (294 aa)
	A0A162NHW8	Uncharacterized protein. (488 aa)
	TIF6	Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. Is also involved in ribosome biogenesis. Associates with pre-60S subunits in the nucleus and is involved in its nuclear export; Belongs to the eIF-6 family. (245 aa)
	A0A162PZ41	Uncharacterized protein. (311 aa)
	A0A162T8G3	TRASH domain-containing protein. (159 aa)
	A0A167MVK1	Uncharacterized protein. (525 aa)
	A0A167MNS9	Uncharacterized protein; Belongs to the AAA ATPase family. (542 aa)
	A0A167ME98	Uncharacterized protein. (234 aa)
	A0A167MB73	Uncharacterized protein. (1869 aa)
	A0A167M5G2	60S acidic ribosomal protein P0; Ribosomal protein P0 is the functional equivalent of E.coli protein L10. (310 aa)
	A0A167M3D0	SAM_MT_RSMB_NOP domain-containing protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. (505 aa)
	A0A167LM51	Nucleolar GTP-binding protein 1; Involved in the biogenesis of the 60S ribosomal subunit. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. NOG subfamily. (639 aa)
	A0A163A9B0	Protein SDA1; Required for 60S pre-ribosomal subunits export to the cytoplasm; Belongs to the SDA1 family. (699 aa)
	NOP7	Pescadillo homolog; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome. (537 aa)
	A0A163B4Y4	Uncharacterized protein. (249 aa)
	A0A167L6V2	J domain-containing protein. (264 aa)
	A0A163BCD3	Uncharacterized protein. (249 aa)
	A0A163BD86	Ribosomal_L23eN domain-containing protein; Belongs to the universal ribosomal protein uL23 family. (145 aa)
	A0A163E803	Ribosomal_L18_c domain-containing protein. (293 aa)
	A0A163EBT8	Uncharacterized protein. (267 aa)
	A0A167JCI4	HIT-type domain-containing protein. (424 aa)
	A0A167R8Z2	Uncharacterized protein. (510 aa)
	A0A162N5C8	Brix domain-containing protein. (301 aa)
	A0A162NBT3	PUM-HD domain-containing protein. (554 aa)
	YTM1	Ribosome biogenesis protein YTM1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome. (440 aa)
	A0A162NGB6	HIT-type domain-containing protein. (450 aa)
	A0A167R2V5	Ribosome biogenesis protein NOP53; May play a role in ribosome biogenesis. Belongs to the NOP53 family. (431 aa)
	A0A163A378	Uncharacterized protein. (234 aa)
	A0A162TV89	Brix domain-containing protein. (323 aa)
	A0A162TRI9	WD_REPEATS_REGION domain-containing protein. (467 aa)
	A0A162ZTC4	Uncharacterized protein. (243 aa)
	ERB1	Ribosome biogenesis protein ERB1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome. (638 aa)
	A0A162UY32	C2H2-type zinc finger transcription factor. (310 aa)
	A0A162UXW7	Ribosome biogenesis regulatory protein; Involved in ribosomal large subunit assembly. Belongs to the RRS1 family. (230 aa)
	A0A162UX15	Uncharacterized protein. (666 aa)
	A0A162UTY8	Ribosomal_L14e domain-containing protein. (138 aa)
	A0A162UN62	CP-type G domain-containing protein. (672 aa)
	A0A162UMT3	Brix domain-containing protein. (291 aa)
	A0A162UEB0	Ribosomal_L28e domain-containing protein. (243 aa)
	A0A162UAC7	Uncharacterized protein. (251 aa)
	A0A162U984	Uncharacterized protein. (123 aa)
	A0A167JJT0	Uncharacterized protein; Belongs to the AAA ATPase family. (641 aa)
	A0A167KA75	Uncharacterized protein. (699 aa)
	A0A167KDF4	Uncharacterized protein. (249 aa)
	A0A167KLW3	Uncharacterized protein. (105 aa)
	A0A167QD21	RRM domain-containing protein. (149 aa)
	A0A167QGG7	Uncharacterized protein. (786 aa)
	A0A167QQG4	Uncharacterized protein. (265 aa)
	A0A167QTH7	Uncharacterized protein. (1451 aa)
	A0A167QYZ2	Uncharacterized protein. (251 aa)
	A0A167R0U2	Ribosomal_L14e domain-containing protein. (137 aa)
	A0A167KX43	Uncharacterized protein. (227 aa)
	A0A163A3I5	WD_REPEATS_REGION domain-containing protein. (277 aa)
	A0A163A5N5	Uncharacterized protein. (108 aa)
	A0A167REX1	WD_REPEATS_REGION domain-containing protein. (433 aa)

Your Current Organism:

Phycomyces blakesleeanus

NCBI taxonomy Id: 763407
Other names: P. blakesleeanus NRRL 1555(-), Phycomyces blakesleeanus NRRL 1555(-)

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A162N5C8	A0A162NBT3	A0A162N5C8	A0A162NBT3	Brix domain-containing protein.	PUM-HD domain-containing protein.	0.940
A0A162N5C8	A0A162NHW8	A0A162N5C8	A0A162NHW8	Brix domain-containing protein.	Uncharacterized protein.	0.451
A0A162N5C8	A0A162T8G3	A0A162N5C8	A0A162T8G3	Brix domain-containing protein.	TRASH domain-containing protein.	0.988
A0A162N5C8	A0A162TV89	A0A162N5C8	A0A162TV89	Brix domain-containing protein.	Brix domain-containing protein.	0.989
A0A162N5C8	A0A162UAC7	A0A162N5C8	A0A162UAC7	Brix domain-containing protein.	Uncharacterized protein.	0.990
A0A162N5C8	A0A162UEB0	A0A162N5C8	A0A162UEB0	Brix domain-containing protein.	Ribosomal_L28e domain-containing protein.	0.998
A0A162N5C8	A0A162UMT3	A0A162N5C8	A0A162UMT3	Brix domain-containing protein.	Brix domain-containing protein.	0.995
A0A162N5C8	A0A162UN62	A0A162N5C8	A0A162UN62	Brix domain-containing protein.	CP-type G domain-containing protein.	0.882
A0A162N5C8	A0A162UTY8	A0A162N5C8	A0A162UTY8	Brix domain-containing protein.	Ribosomal_L14e domain-containing protein.	0.894
A0A162N5C8	A0A162UX15	A0A162N5C8	A0A162UX15	Brix domain-containing protein.	Uncharacterized protein.	0.631
A0A162N5C8	A0A162UXW7	A0A162N5C8	A0A162UXW7	Brix domain-containing protein.	Ribosome biogenesis regulatory protein; Involved in ribosomal large subunit assembly. Belongs to the RRS1 family.	0.909
A0A162N5C8	A0A162UY32	A0A162N5C8	A0A162UY32	Brix domain-containing protein.	C2H2-type zinc finger transcription factor.	0.673
A0A162N5C8	A0A162ZTC4	A0A162N5C8	A0A162ZTC4	Brix domain-containing protein.	Uncharacterized protein.	0.965
A0A162N5C8	A0A163A378	A0A162N5C8	A0A163A378	Brix domain-containing protein.	Uncharacterized protein.	0.984
A0A162N5C8	A0A163A5N5	A0A162N5C8	A0A163A5N5	Brix domain-containing protein.	Uncharacterized protein.	0.822
A0A162N5C8	A0A163A9B0	A0A162N5C8	A0A163A9B0	Brix domain-containing protein.	Protein SDA1; Required for 60S pre-ribosomal subunits export to the cytoplasm; Belongs to the SDA1 family.	0.796
A0A162N5C8	A0A163B4Y4	A0A162N5C8	A0A163B4Y4	Brix domain-containing protein.	Uncharacterized protein.	0.965
A0A162N5C8	A0A163BCD3	A0A162N5C8	A0A163BCD3	Brix domain-containing protein.	Uncharacterized protein.	0.883
A0A162N5C8	A0A163BD86	A0A162N5C8	A0A163BD86	Brix domain-containing protein.	Ribosomal_L23eN domain-containing protein; Belongs to the universal ribosomal protein uL23 family.	0.899
A0A162N5C8	A0A163EBT8	A0A162N5C8	A0A163EBT8	Brix domain-containing protein.	Uncharacterized protein.	0.998