(54 nodes) RNA phosphodiester bond hydrolysis, endonucleolytic network (Phycomyces blakesleeanus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	A0A162TTP2	Uncharacterized protein. (234 aa)
	A0A162NHW8	Uncharacterized protein. (488 aa)
	A0A162NKG9	Uncharacterized protein. (616 aa)
	A0A162T2S6	Uncharacterized protein. (86 aa)
	A0A162PV65	Uncharacterized protein; Belongs to the argonaute family. (842 aa)
	A0A162PJ10	WD_REPEATS_REGION domain-containing protein. (531 aa)
	A0A162PH25	Endonuclease. (314 aa)
	A0A167R319	PINc domain-containing protein. (1132 aa)
	A0A162N504	Uncharacterized protein. (335 aa)
	A0A162WQ14	PINc domain-containing protein. (356 aa)
	A0A162UI71	Uncharacterized protein. (373 aa)
	A0A167QWK6	Uncharacterized protein. (408 aa)
	A0A162WKJ9	Lactamase_B domain-containing protein. (283 aa)
	A0A162UJJ9	Uncharacterized protein; Belongs to the argonaute family. (840 aa)
	A0A162UXW7	Ribosome biogenesis regulatory protein; Involved in ribosomal large subunit assembly. Belongs to the RRS1 family. (230 aa)
	A0A162X4W3	WD_REPEATS_REGION domain-containing protein. (515 aa)
	Dcl	DsRNA-specific ribonuclease III dicer; Belongs to the helicase family. Dicer subfamily. (1568 aa)
	A0A162XPY2	tRNA-splicing endonuclease subunit Sen2; Constitutes one of the two catalytic subunit of the tRNA- splicing endonuclease complex, a complex responsible for identification and cleavage of the splice sites in pre-tRNA. It cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3'-cyclic phosphate and 5'-OH termini. There are no conserved sequences at the splice sites, but the intron is invariably located at the same site in the gene, placing the splice sites an invariant distance from the constant structural [...] (342 aa)
	A0A162YDA6	Uncharacterized protein. (256 aa)
	A0A162YIR6	Endonuclease. (271 aa)
	A0A163AUP3	RNase III domain-containing protein. (174 aa)
	A0A163BD10	RNase H domain-containing protein. (369 aa)
	A0A163CV68	Uncharacterized protein. (298 aa)
	A0A163D4D9	DUF663 domain-containing protein. (160 aa)
	A0A163DBS7	PLD phosphodiesterase domain-containing protein. (423 aa)
	A0A163DLU9	Uncharacterized protein. (784 aa)
	A0A163E9F4	Uncharacterized protein; Belongs to the RNase T2 family. (252 aa)
	A0A167JQX3	Sen15 domain-containing protein. (133 aa)
	A0A167K5F2	WD_REPEATS_REGION domain-containing protein. (743 aa)
	A0A167KCW3	Uncharacterized protein. (257 aa)
	A0A167KD26	Secreted ribonuclease T2; Belongs to the RNase T2 family. (280 aa)
	A0A167KGW5	Secreted ribonuclease T2; Belongs to the RNase T2 family. (264 aa)
	A0A167KWY1	Uncharacterized protein. (267 aa)
	A0A167KYG7	Uncharacterized protein. (159 aa)
	A0A167L866	Uncharacterized protein. (333 aa)
	A0A167M886	Uncharacterized protein. (358 aa)
	A0A167MA83	CBF domain-containing protein. (482 aa)
	A0A167MBR6	Uncharacterized protein. (157 aa)
	A0A167MDR3	Uncharacterized protein. (294 aa)
	A0A167MVA8	tRNA_int_endo domain-containing protein. (196 aa)
	A0A167N0Q7	Secreted ribonuclease T2; Belongs to the RNase T2 family. (249 aa)
	A0A167N6J1	40S ribosomal protein S21; Required for the processing of the 20S rRNA-precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits. Has a physiological role leading to 18S rRNA stability. (86 aa)
	A0A167NGS8	Ribonuclease; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family. (280 aa)
	A0A167NJM4	POP4 domain-containing protein. (171 aa)
	A0A167NMJ7	Fcf2 domain-containing protein. (347 aa)
	A0A167PT46	RNase H domain-containing protein. (153 aa)
	A0A167Q169	DBR1 domain-containing protein. (350 aa)
	A0A167QH99	Uncharacterized protein. (470 aa)
	A0A167QJ69	Uncharacterized protein. (813 aa)
	A0A167QTH2	Bms1-type G domain-containing protein. (1170 aa)
	A0A167QTH7	Uncharacterized protein. (1451 aa)
	A0A162V3U6	WD_REPEATS_REGION domain-containing protein. (930 aa)
	A0A167R716	20S-pre-rRNA D-site endonuclease NOB1; Required for the synthesis of 40S ribosome subunits. Has a role in processing 20S pre-rRNA into the mature 18S rRNA, where it is required for cleavage at the 3' end of the mature 18S rRNA (D-site). Accompanies the 20S pre-rRNA from the nucleus to the cytoplasm. Belongs to the NOB1 family. (407 aa)
	A0A162U2V6	PINc domain-containing protein. (195 aa)

Your Current Organism:

Phycomyces blakesleeanus

NCBI taxonomy Id: 763407
Other names: P. blakesleeanus NRRL 1555(-), Phycomyces blakesleeanus NRRL 1555(-)

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A162N504	A0A162NHW8	A0A162N504	A0A162NHW8	Uncharacterized protein.	Uncharacterized protein.	0.405
A0A162N504	A0A162PJ10	A0A162N504	A0A162PJ10	Uncharacterized protein.	WD_REPEATS_REGION domain-containing protein.	0.999
A0A162N504	A0A162TTP2	A0A162N504	A0A162TTP2	Uncharacterized protein.	Uncharacterized protein.	0.776
A0A162N504	A0A162U2V6	A0A162N504	A0A162U2V6	Uncharacterized protein.	PINc domain-containing protein.	0.980
A0A162N504	A0A162UXW7	A0A162N504	A0A162UXW7	Uncharacterized protein.	Ribosome biogenesis regulatory protein; Involved in ribosomal large subunit assembly. Belongs to the RRS1 family.	0.907
A0A162N504	A0A162V3U6	A0A162N504	A0A162V3U6	Uncharacterized protein.	WD_REPEATS_REGION domain-containing protein.	0.999
A0A162N504	A0A162X4W3	A0A162N504	A0A162X4W3	Uncharacterized protein.	WD_REPEATS_REGION domain-containing protein.	0.999
A0A162N504	A0A163D4D9	A0A162N504	A0A163D4D9	Uncharacterized protein.	DUF663 domain-containing protein.	0.999
A0A162N504	A0A167K5F2	A0A162N504	A0A167K5F2	Uncharacterized protein.	WD_REPEATS_REGION domain-containing protein.	0.996
A0A162N504	A0A167KCW3	A0A162N504	A0A167KCW3	Uncharacterized protein.	Uncharacterized protein.	0.878
A0A162N504	A0A167KWY1	A0A162N504	A0A167KWY1	Uncharacterized protein.	Uncharacterized protein.	0.814
A0A162N504	A0A167M886	A0A162N504	A0A167M886	Uncharacterized protein.	Uncharacterized protein.	0.998
A0A162N504	A0A167MA83	A0A162N504	A0A167MA83	Uncharacterized protein.	CBF domain-containing protein.	0.998
A0A162N504	A0A167MBR6	A0A162N504	A0A167MBR6	Uncharacterized protein.	Uncharacterized protein.	0.684
A0A162N504	A0A167N6J1	A0A162N504	A0A167N6J1	Uncharacterized protein.	40S ribosomal protein S21; Required for the processing of the 20S rRNA-precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits. Has a physiological role leading to 18S rRNA stability.	0.996
A0A162N504	A0A167NMJ7	A0A162N504	A0A167NMJ7	Uncharacterized protein.	Fcf2 domain-containing protein.	0.964
A0A162N504	A0A167QTH2	A0A162N504	A0A167QTH2	Uncharacterized protein.	Bms1-type G domain-containing protein.	0.999
A0A162N504	A0A167QTH7	A0A162N504	A0A167QTH7	Uncharacterized protein.	Uncharacterized protein.	0.998
A0A162N504	A0A167R716	A0A162N504	A0A167R716	Uncharacterized protein.	20S-pre-rRNA D-site endonuclease NOB1; Required for the synthesis of 40S ribosome subunits. Has a role in processing 20S pre-rRNA into the mature 18S rRNA, where it is required for cleavage at the 3' end of the mature 18S rRNA (D-site). Accompanies the 20S pre-rRNA from the nucleus to the cytoplasm. Belongs to the NOB1 family.	0.999
A0A162NHW8	A0A162N504	A0A162NHW8	A0A162N504	Uncharacterized protein.	Uncharacterized protein.	0.405