(35 nodes) RNA polymerase II, holoenzyme network (Phycomyces blakesleeanus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	A0A167JIV2	WD_REPEATS_REGION domain-containing protein. (323 aa)
	A0A167JU51	RING-type domain-containing protein. (105 aa)
	A0A167JY79	Uncharacterized protein. (296 aa)
	A0A167KKY6	Uncharacterized protein. (176 aa)
	A0A167KYZ7	Uncharacterized protein. (647 aa)
	A0A167LFS1	Bromo domain-containing protein. (72 aa)
	A0A167LFS7	Uncharacterized protein. (849 aa)
	A0A167ML90	Uncharacterized protein. (129 aa)
	A0A167MRV2	Uncharacterized protein. (396 aa)
	A0A167N1D2	BSD domain-containing protein. (624 aa)
	A0A167NAY7	Uncharacterized protein. (122 aa)
	A0A167NFL0	Plus3 domain-containing protein. (536 aa)
	A0A167NL99	RNA_pol_L_2 domain-containing protein. (149 aa)
	A0A167PTU1	Transcription initiation factor IIA subunit 2; TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation; Belongs to the TFIIA subunit 2 family. (112 aa)
	A0A167QFB1	Cyclin; Belongs to the cyclin family. (338 aa)
	A0A167QQ08	Uncharacterized protein. (75 aa)
	A0A167RCM9	Uncharacterized protein. (116 aa)
	A0A162T8U4	Protein kinase domain-containing protein. (353 aa)
	A0A162TN21	Uncharacterized protein. (147 aa)
	A0A162TV25	Uncharacterized protein. (700 aa)
	A0A162TY78	Uncharacterized protein. (209 aa)
	A0A162UGY5	TFIID_20kDa domain-containing protein. (103 aa)
	A0A162UM41	Uncharacterized protein. (143 aa)
	A0A162Q141	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (313 aa)
	A0A162UV10	Uncharacterized protein. (283 aa)
	A0A162V0U7	Uncharacterized protein. (116 aa)
	A0A162XK73	Uncharacterized protein. (315 aa)
	A0A162XV76	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (114 aa)
	A0A162XXD6	RNA polymerase II transcription factor B subunit 2; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family. (453 aa)
	A0A162ZVW2	Transcription initiation factor IIE subunit beta; Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase. (284 aa)
	A0A162ZY90	General transcription and DNA repair factor IIH; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to TFIIK, in RNA transcription by RNA polymerase II; Belongs to the GTF2H2 family. (410 aa)
	A0A163AKQ3	TAFII28 domain-containing protein. (118 aa)
	A0A163D9S9	F-box domain-containing protein. (277 aa)
	A0A167JHR9	HTH TFE/IIEalpha-type domain-containing protein. (430 aa)
	A0A162NAF9	TATA box binding protein associated factor. (453 aa)

Your Current Organism:

Phycomyces blakesleeanus

NCBI taxonomy Id: 763407
Other names: P. blakesleeanus NRRL 1555(-), Phycomyces blakesleeanus NRRL 1555(-)

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Browse interactions in tabular form:

node1	node2	node1 annotation	node2 annotation	score
A0A162NAF9	A0A162Q141	TATA box binding protein associated factor.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.864
A0A162NAF9	A0A162T8U4	TATA box binding protein associated factor.	Protein kinase domain-containing protein.	0.811
A0A162NAF9	A0A162TN21	TATA box binding protein associated factor.	Uncharacterized protein.	0.937
A0A162NAF9	A0A162TV25	TATA box binding protein associated factor.	Uncharacterized protein.	0.999
A0A162NAF9	A0A162TY78	TATA box binding protein associated factor.	Uncharacterized protein.	0.926
A0A162NAF9	A0A162UGY5	TATA box binding protein associated factor.	TFIID_20kDa domain-containing protein.	0.999
A0A162NAF9	A0A162UM41	TATA box binding protein associated factor.	Uncharacterized protein.	0.999
A0A162NAF9	A0A162V0U7	TATA box binding protein associated factor.	Uncharacterized protein.	0.999
A0A162NAF9	A0A162XK73	TATA box binding protein associated factor.	Uncharacterized protein.	0.906
A0A162NAF9	A0A162XV76	TATA box binding protein associated factor.	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.	0.907
A0A162NAF9	A0A162XXD6	TATA box binding protein associated factor.	RNA polymerase II transcription factor B subunit 2; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family.	0.902
A0A162NAF9	A0A162ZVW2	TATA box binding protein associated factor.	Transcription initiation factor IIE subunit beta; Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase.	0.893
A0A162NAF9	A0A162ZY90	TATA box binding protein associated factor.	General transcription and DNA repair factor IIH; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to TFIIK, in RNA transcription by RNA polymerase II; Belongs to the GTF2H2 family.	0.859
A0A162NAF9	A0A163AKQ3	TATA box binding protein associated factor.	TAFII28 domain-containing protein.	0.999
A0A162NAF9	A0A163D9S9	TATA box binding protein associated factor.	F-box domain-containing protein.	0.859
A0A162NAF9	A0A167JHR9	TATA box binding protein associated factor.	HTH TFE/IIEalpha-type domain-containing protein.	0.972
A0A162NAF9	A0A167JU51	TATA box binding protein associated factor.	RING-type domain-containing protein.	0.919
A0A162NAF9	A0A167JY79	TATA box binding protein associated factor.	Uncharacterized protein.	0.928
A0A162NAF9	A0A167KYZ7	TATA box binding protein associated factor.	Uncharacterized protein.	0.999
A0A162NAF9	A0A167LFS1	TATA box binding protein associated factor.	Bromo domain-containing protein.	0.979