(40 nodes) Ribonuclease H-like superfamily network (Phycomyces blakesleeanus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	A0A167L655	3'-5' exonuclease domain-containing protein. (324 aa)
	A0A167L6I3	Uncharacterized protein. (619 aa)
	A0A167LCA4	Exonuclease domain-containing protein. (181 aa)
	A0A167MI72	DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2213 aa)
	A0A167MT18	MPN domain-containing protein. (2555 aa)
	A0A167NGS8	Ribonuclease; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family. (280 aa)
	A0A167NM89	DNA polymerase. (1151 aa)
	A0A167NUK9	S1 motif domain-containing protein. (1318 aa)
	A0A167NZD7	CCCH-type zinc finger transcription factor. (437 aa)
	A0A167PSM1	Exonuclease domain-containing protein. (169 aa)
	A0A167PT46	RNase H domain-containing protein. (153 aa)
	PAN2	PAN2-PAN3 deadenylation complex catalytic subunit PAN2; Catalytic subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein PAB1. PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA decaping and subsequent [...] (1102 aa)
	A0A167RG03	Integrase catalytic domain-containing protein. (67 aa)
	A0A167QEH4	Uncharacterized protein. (351 aa)
	A0A162N6V4	Uncharacterized protein. (406 aa)
	A0A162N8M9	SAP domain-containing protein. (282 aa)
	A0A162N9M7	Integrase catalytic domain-containing protein. (77 aa)
	A0A162NM81	Uncharacterized protein. (148 aa)
	A0A162PNP4	Integrase catalytic domain-containing protein. (51 aa)
	A0A162PV65	Uncharacterized protein; Belongs to the argonaute family. (842 aa)
	A0A162Q0J9	POLAc domain-containing protein. (1015 aa)
	A0A162Q3L3	3'-5' exonuclease domain-containing protein. (840 aa)
	A0A162UCQ1	SAP domain-containing protein. (276 aa)
	A0A162UDI8	Uncharacterized protein. (563 aa)
	A0A162UGC7	DNA polymerase. (828 aa)
	A0A162UJJ9	Uncharacterized protein; Belongs to the argonaute family. (840 aa)
	A0A162V4U7	DDE_3 domain-containing protein. (102 aa)
	A0A162V5V7	Integrase catalytic domain-containing protein. (145 aa)
	A0A162VAV6	MPN domain-containing protein. (2557 aa)
	A0A162W790	Uncharacterized protein. (93 aa)
	A0A162XGD3	Exonuclease domain-containing protein. (606 aa)
	A0A162Y4Q0	Uncharacterized protein. (353 aa)
	A0A162YIF7	Exonuclease domain-containing protein. (742 aa)
	A0A163AD41	Uncharacterized protein. (266 aa)
	A0A163B3Q7	3'-5' exonuclease domain-containing protein. (1150 aa)
	A0A163BD10	RNase H domain-containing protein. (369 aa)
	A0A163BD23	Exonuclease domain-containing protein. (546 aa)
	A0A163D1U8	DNA polymerase. (1072 aa)
	A0A167L3A2	HRDC domain-containing protein. (528 aa)
	A0A167L5R1	Uncharacterized protein. (253 aa)

Your Current Organism:

Phycomyces blakesleeanus

NCBI taxonomy Id: 763407
Other names: P. blakesleeanus NRRL 1555(-), Phycomyces blakesleeanus NRRL 1555(-)

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A162N6V4	A0A167L5R1	A0A162N6V4	A0A167L5R1	Uncharacterized protein.	Uncharacterized protein.	0.414
A0A162PV65	A0A162UCQ1	A0A162PV65	A0A162UCQ1	Uncharacterized protein; Belongs to the argonaute family.	SAP domain-containing protein.	0.463
A0A162PV65	A0A167L5R1	A0A162PV65	A0A167L5R1	Uncharacterized protein; Belongs to the argonaute family.	Uncharacterized protein.	0.458
A0A162Q0J9	A0A162UGC7	A0A162Q0J9	A0A162UGC7	POLAc domain-containing protein.	DNA polymerase.	0.632
A0A162Q0J9	A0A162XGD3	A0A162Q0J9	A0A162XGD3	POLAc domain-containing protein.	Exonuclease domain-containing protein.	0.521
A0A162Q0J9	A0A162YIF7	A0A162Q0J9	A0A162YIF7	POLAc domain-containing protein.	Exonuclease domain-containing protein.	0.521
A0A162Q0J9	A0A163BD10	A0A162Q0J9	A0A163BD10	POLAc domain-containing protein.	RNase H domain-containing protein.	0.837
A0A162Q0J9	A0A163BD23	A0A162Q0J9	A0A163BD23	POLAc domain-containing protein.	Exonuclease domain-containing protein.	0.521
A0A162Q0J9	A0A163D1U8	A0A162Q0J9	A0A163D1U8	POLAc domain-containing protein.	DNA polymerase.	0.439
A0A162Q0J9	A0A167L655	A0A162Q0J9	A0A167L655	POLAc domain-containing protein.	3'-5' exonuclease domain-containing protein.	0.537
A0A162Q0J9	A0A167MI72	A0A162Q0J9	A0A167MI72	POLAc domain-containing protein.	DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family.	0.625
A0A162Q0J9	A0A167NGS8	A0A162Q0J9	A0A167NGS8	POLAc domain-containing protein.	Ribonuclease; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family.	0.565
A0A162Q0J9	A0A167NM89	A0A162Q0J9	A0A167NM89	POLAc domain-containing protein.	DNA polymerase.	0.439
A0A162Q0J9	A0A167PSM1	A0A162Q0J9	A0A167PSM1	POLAc domain-containing protein.	Exonuclease domain-containing protein.	0.521
A0A162Q0J9	A0A167PT46	A0A162Q0J9	A0A167PT46	POLAc domain-containing protein.	RNase H domain-containing protein.	0.837
A0A162Q0J9	PAN2	A0A162Q0J9	A0A167PZD3	POLAc domain-containing protein.	PAN2-PAN3 deadenylation complex catalytic subunit PAN2; Catalytic subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein PAB1. PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA decaping and subsequent [...]	0.521
A0A162UCQ1	A0A162PV65	A0A162UCQ1	A0A162PV65	SAP domain-containing protein.	Uncharacterized protein; Belongs to the argonaute family.	0.463
A0A162UCQ1	A0A162UJJ9	A0A162UCQ1	A0A162UJJ9	SAP domain-containing protein.	Uncharacterized protein; Belongs to the argonaute family.	0.463
A0A162UGC7	A0A162Q0J9	A0A162UGC7	A0A162Q0J9	DNA polymerase.	POLAc domain-containing protein.	0.632
A0A162UGC7	A0A163D1U8	A0A162UGC7	A0A163D1U8	DNA polymerase.	DNA polymerase.	0.895