(38 nodes) Formation of the Early Elongation Complex network (Phycomyces blakesleeanus)

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second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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experimentally determined

Predicted Interactions

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Your Input:
	A0A162Q141	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (313 aa)
	A0A167NL99	RNA_pol_L_2 domain-containing protein. (149 aa)
	A0A167NAY7	Uncharacterized protein. (122 aa)
	A0A167N7L9	Uncharacterized protein. (171 aa)
	A0A167N1D2	BSD domain-containing protein. (624 aa)
	A0A167MIZ8	Uncharacterized protein. (283 aa)
	A0A167K5N4	Uncharacterized protein. (558 aa)
	A0A162TC68	Uncharacterized protein. (62 aa)
	A0A162TJG1	Uncharacterized protein. (784 aa)
	A0A163A6F8	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (599 aa)
	A0A162ZY90	General transcription and DNA repair factor IIH; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to TFIIK, in RNA transcription by RNA polymerase II; Belongs to the GTF2H2 family. (410 aa)
	A0A162ZY31	Uncharacterized protein. (171 aa)
	A0A167RCM9	Uncharacterized protein. (116 aa)
	A0A167QXW1	Uncharacterized protein. (58 aa)
	A0A167QQ08	Uncharacterized protein. (75 aa)
	A0A167QFB1	Cyclin; Belongs to the cyclin family. (338 aa)
	A0A167PAA2	Uncharacterized protein. (335 aa)
	A0A162XK73	Uncharacterized protein. (315 aa)
	A0A162XE97	Uncharacterized protein. (776 aa)
	A0A162X8R1	Helicase ATP-binding domain-containing protein. (767 aa)
	A0A162WP08	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1195 aa)
	A0A162VB61	FCP1 homology domain-containing protein. (515 aa)
	A0A162UVW1	Nuclear cap-binding protein subunit 2. (218 aa)
	A0A162TY78	Uncharacterized protein. (209 aa)
	A0A167JU51	RING-type domain-containing protein. (105 aa)
	A0A167JU24	MARVEL domain-containing protein. (330 aa)
	A0A163DLL7	RNA polymerase II subunit A C-terminal domain phosphatase; This promotes the activity of RNA polymerase II. (583 aa)
	A0A163D9S9	F-box domain-containing protein. (277 aa)
	A0A163AH94	RPOL4c domain-containing protein. (145 aa)
	A0A162XV76	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (114 aa)
	A0A162ZUB8	Uncharacterized protein. (165 aa)
	A0A162ZKV2	Uncharacterized protein. (575 aa)
	A0A162ZJ50	Uncharacterized protein. (419 aa)
	A0A162XXD6	RNA polymerase II transcription factor B subunit 2; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family. (453 aa)
	A0A167JY79	Uncharacterized protein. (296 aa)
	A0A162NE68	Transcription elongation factor SPT4; The SPT4-SPT5 complex mediates both activation and inhibition of transcription elongation, and plays a role in pre-mRNA processing. This complex seems to be important for the stability of the RNA polymerase II elongation machinery on the chromatin template but not for the inherent ability of this machinery to translocate down the gene. (116 aa)
	A0A162NH54	Uncharacterized protein. (58 aa)
	A0A162PQY1	Uncharacterized protein. (849 aa)

Your Current Organism:

Phycomyces blakesleeanus

NCBI taxonomy Id: 763407
Other names: P. blakesleeanus NRRL 1555(-), Phycomyces blakesleeanus NRRL 1555(-)

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Browse interactions in tabular form:

node1	node2	node1 annotation	node2 annotation	score
A0A162NE68	A0A162NH54	Transcription elongation factor SPT4; The SPT4-SPT5 complex mediates both activation and inhibition of transcription elongation, and plays a role in pre-mRNA processing. This complex seems to be important for the stability of the RNA polymerase II elongation machinery on the chromatin template but not for the inherent ability of this machinery to translocate down the gene.	Uncharacterized protein.	0.968
A0A162NE68	A0A162PQY1	Transcription elongation factor SPT4; The SPT4-SPT5 complex mediates both activation and inhibition of transcription elongation, and plays a role in pre-mRNA processing. This complex seems to be important for the stability of the RNA polymerase II elongation machinery on the chromatin template but not for the inherent ability of this machinery to translocate down the gene.	Uncharacterized protein.	0.730
A0A162NE68	A0A162Q141	Transcription elongation factor SPT4; The SPT4-SPT5 complex mediates both activation and inhibition of transcription elongation, and plays a role in pre-mRNA processing. This complex seems to be important for the stability of the RNA polymerase II elongation machinery on the chromatin template but not for the inherent ability of this machinery to translocate down the gene.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.846
A0A162NE68	A0A162TC68	Transcription elongation factor SPT4; The SPT4-SPT5 complex mediates both activation and inhibition of transcription elongation, and plays a role in pre-mRNA processing. This complex seems to be important for the stability of the RNA polymerase II elongation machinery on the chromatin template but not for the inherent ability of this machinery to translocate down the gene.	Uncharacterized protein.	0.983
A0A162NE68	A0A162TJG1	Transcription elongation factor SPT4; The SPT4-SPT5 complex mediates both activation and inhibition of transcription elongation, and plays a role in pre-mRNA processing. This complex seems to be important for the stability of the RNA polymerase II elongation machinery on the chromatin template but not for the inherent ability of this machinery to translocate down the gene.	Uncharacterized protein.	0.979
A0A162NE68	A0A162TY78	Transcription elongation factor SPT4; The SPT4-SPT5 complex mediates both activation and inhibition of transcription elongation, and plays a role in pre-mRNA processing. This complex seems to be important for the stability of the RNA polymerase II elongation machinery on the chromatin template but not for the inherent ability of this machinery to translocate down the gene.	Uncharacterized protein.	0.995
A0A162NE68	A0A162UVW1	Transcription elongation factor SPT4; The SPT4-SPT5 complex mediates both activation and inhibition of transcription elongation, and plays a role in pre-mRNA processing. This complex seems to be important for the stability of the RNA polymerase II elongation machinery on the chromatin template but not for the inherent ability of this machinery to translocate down the gene.	Nuclear cap-binding protein subunit 2.	0.838
A0A162NE68	A0A162VB61	Transcription elongation factor SPT4; The SPT4-SPT5 complex mediates both activation and inhibition of transcription elongation, and plays a role in pre-mRNA processing. This complex seems to be important for the stability of the RNA polymerase II elongation machinery on the chromatin template but not for the inherent ability of this machinery to translocate down the gene.	FCP1 homology domain-containing protein.	0.801
A0A162NE68	A0A162WP08	Transcription elongation factor SPT4; The SPT4-SPT5 complex mediates both activation and inhibition of transcription elongation, and plays a role in pre-mRNA processing. This complex seems to be important for the stability of the RNA polymerase II elongation machinery on the chromatin template but not for the inherent ability of this machinery to translocate down the gene.	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.998
A0A162NE68	A0A162XE97	Transcription elongation factor SPT4; The SPT4-SPT5 complex mediates both activation and inhibition of transcription elongation, and plays a role in pre-mRNA processing. This complex seems to be important for the stability of the RNA polymerase II elongation machinery on the chromatin template but not for the inherent ability of this machinery to translocate down the gene.	Uncharacterized protein.	0.704
A0A162NE68	A0A162XV76	Transcription elongation factor SPT4; The SPT4-SPT5 complex mediates both activation and inhibition of transcription elongation, and plays a role in pre-mRNA processing. This complex seems to be important for the stability of the RNA polymerase II elongation machinery on the chromatin template but not for the inherent ability of this machinery to translocate down the gene.	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.	0.994
A0A162NE68	A0A162ZJ50	Transcription elongation factor SPT4; The SPT4-SPT5 complex mediates both activation and inhibition of transcription elongation, and plays a role in pre-mRNA processing. This complex seems to be important for the stability of the RNA polymerase II elongation machinery on the chromatin template but not for the inherent ability of this machinery to translocate down the gene.	Uncharacterized protein.	0.669
A0A162NE68	A0A162ZKV2	Transcription elongation factor SPT4; The SPT4-SPT5 complex mediates both activation and inhibition of transcription elongation, and plays a role in pre-mRNA processing. This complex seems to be important for the stability of the RNA polymerase II elongation machinery on the chromatin template but not for the inherent ability of this machinery to translocate down the gene.	Uncharacterized protein.	0.943
A0A162NE68	A0A162ZUB8	Transcription elongation factor SPT4; The SPT4-SPT5 complex mediates both activation and inhibition of transcription elongation, and plays a role in pre-mRNA processing. This complex seems to be important for the stability of the RNA polymerase II elongation machinery on the chromatin template but not for the inherent ability of this machinery to translocate down the gene.	Uncharacterized protein.	0.979
A0A162NE68	A0A162ZY31	Transcription elongation factor SPT4; The SPT4-SPT5 complex mediates both activation and inhibition of transcription elongation, and plays a role in pre-mRNA processing. This complex seems to be important for the stability of the RNA polymerase II elongation machinery on the chromatin template but not for the inherent ability of this machinery to translocate down the gene.	Uncharacterized protein.	0.981
A0A162NE68	A0A162ZY90	Transcription elongation factor SPT4; The SPT4-SPT5 complex mediates both activation and inhibition of transcription elongation, and plays a role in pre-mRNA processing. This complex seems to be important for the stability of the RNA polymerase II elongation machinery on the chromatin template but not for the inherent ability of this machinery to translocate down the gene.	General transcription and DNA repair factor IIH; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to TFIIK, in RNA transcription by RNA polymerase II; Belongs to the GTF2H2 family.	0.708
A0A162NE68	A0A163A6F8	Transcription elongation factor SPT4; The SPT4-SPT5 complex mediates both activation and inhibition of transcription elongation, and plays a role in pre-mRNA processing. This complex seems to be important for the stability of the RNA polymerase II elongation machinery on the chromatin template but not for the inherent ability of this machinery to translocate down the gene.	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.998
A0A162NE68	A0A163AH94	Transcription elongation factor SPT4; The SPT4-SPT5 complex mediates both activation and inhibition of transcription elongation, and plays a role in pre-mRNA processing. This complex seems to be important for the stability of the RNA polymerase II elongation machinery on the chromatin template but not for the inherent ability of this machinery to translocate down the gene.	RPOL4c domain-containing protein.	0.997
A0A162NE68	A0A163D9S9	Transcription elongation factor SPT4; The SPT4-SPT5 complex mediates both activation and inhibition of transcription elongation, and plays a role in pre-mRNA processing. This complex seems to be important for the stability of the RNA polymerase II elongation machinery on the chromatin template but not for the inherent ability of this machinery to translocate down the gene.	F-box domain-containing protein.	0.708
A0A162NE68	A0A163DLL7	Transcription elongation factor SPT4; The SPT4-SPT5 complex mediates both activation and inhibition of transcription elongation, and plays a role in pre-mRNA processing. This complex seems to be important for the stability of the RNA polymerase II elongation machinery on the chromatin template but not for the inherent ability of this machinery to translocate down the gene.	RNA polymerase II subunit A C-terminal domain phosphatase; This promotes the activity of RNA polymerase II.	0.846