(32 nodes) DNA Double Strand Break Response network (Phycomyces blakesleeanus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	A0A162XWB5	C2H2-type zinc finger transcription factor. (329 aa)
	A0A162YCM2	AAA_23 domain-containing protein. (86 aa)
	A0A162ZW26	Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (96 aa)
	A0A163AF23	Histone H2B; Belongs to the histone H2B family. (126 aa)
	A0A163AWM6	FHA domain-containing protein. (422 aa)
	A0A163D0E4	Uncharacterized protein. (172 aa)
	A0A163D5P0	Histone H2B; Belongs to the histone H2B family. (125 aa)
	A0A163DNI4	Uncharacterized protein. (205 aa)
	A0A167JJW8	Uncharacterized protein. (186 aa)
	A0A167KJS4	Ubiquitin-like domain-containing protein. (153 aa)
	A0A167KWM3	Uncharacterized protein. (222 aa)
	A0A167KZU6	Uncharacterized protein. (250 aa)
	A0A167R6J7	Uncharacterized protein. (533 aa)
	A0A167KZV4	Uncharacterized protein. (264 aa)
	A0A167LCG4	MPN domain-containing protein. (452 aa)
	A0A167PPU5	Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (472 aa)
	A0A167R601	Uncharacterized protein. (517 aa)
	A0A167R2X0	Ubiquitin-like domain-containing protein. (155 aa)
	A0A162N642	KxDL domain-containing protein. (111 aa)
	A0A162N8V3	Uncharacterized protein. (679 aa)
	A0A162NCC9	Histone H2B; Belongs to the histone H2B family. (148 aa)
	A0A162NG38	Uncharacterized protein. (240 aa)
	A0A167RD89	Ubiquitin-like domain-containing protein. (155 aa)
	Chk2	Checkpoint kinase 2-like protein. (559 aa)
	A0A162NM20	Homeodomain-like DNA binding domain-containing transcription factor. (1015 aa)
	A0A162PRI3	Uncharacterized protein. (357 aa)
	A0A162Q3V1	Uncharacterized protein. (267 aa)
	A0A162T215	Mre11_DNA_bind domain-containing protein; Belongs to the MRE11/RAD32 family. (392 aa)
	A0A162TKK7	Homeodomain-like DNA binding domain-containing transcription factor. (1052 aa)
	A0A162TRM8	FHA domain-containing protein. (159 aa)
	A0A162WLU0	Histone H2B; Belongs to the histone H2B family. (126 aa)
	A0A162XG32	Uncharacterized protein. (213 aa)

Your Current Organism:

Phycomyces blakesleeanus

NCBI taxonomy Id: 763407
Other names: P. blakesleeanus NRRL 1555(-), Phycomyces blakesleeanus NRRL 1555(-)

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A162N642	A0A167KJS4	A0A162N642	A0A167KJS4	KxDL domain-containing protein.	Ubiquitin-like domain-containing protein.	0.707
A0A162N642	A0A167KWM3	A0A162N642	A0A167KWM3	KxDL domain-containing protein.	Uncharacterized protein.	0.692
A0A162N642	A0A167R2X0	A0A162N642	A0A167R2X0	KxDL domain-containing protein.	Ubiquitin-like domain-containing protein.	0.707
A0A162N642	A0A167R6J7	A0A162N642	A0A167R6J7	KxDL domain-containing protein.	Uncharacterized protein.	0.692
A0A162N642	A0A167RD89	A0A162N642	A0A167RD89	KxDL domain-containing protein.	Ubiquitin-like domain-containing protein.	0.707
A0A162N8V3	A0A162Q3V1	A0A162N8V3	A0A162Q3V1	Uncharacterized protein.	Uncharacterized protein.	0.522
A0A162N8V3	A0A162T215	A0A162N8V3	A0A162T215	Uncharacterized protein.	Mre11_DNA_bind domain-containing protein; Belongs to the MRE11/RAD32 family.	0.629
A0A162N8V3	A0A162YCM2	A0A162N8V3	A0A162YCM2	Uncharacterized protein.	AAA_23 domain-containing protein.	0.522
A0A162N8V3	A0A163D0E4	A0A162N8V3	A0A163D0E4	Uncharacterized protein.	Uncharacterized protein.	0.550
A0A162N8V3	A0A167KJS4	A0A162N8V3	A0A167KJS4	Uncharacterized protein.	Ubiquitin-like domain-containing protein.	0.619
A0A162N8V3	A0A167KWM3	A0A162N8V3	A0A167KWM3	Uncharacterized protein.	Uncharacterized protein.	0.588
A0A162N8V3	A0A167R2X0	A0A162N8V3	A0A167R2X0	Uncharacterized protein.	Ubiquitin-like domain-containing protein.	0.619
A0A162N8V3	A0A167R6J7	A0A162N8V3	A0A167R6J7	Uncharacterized protein.	Uncharacterized protein.	0.588
A0A162N8V3	A0A167RD89	A0A162N8V3	A0A167RD89	Uncharacterized protein.	Ubiquitin-like domain-containing protein.	0.619
A0A162N8V3	Chk2	A0A162N8V3	A0A162NH26	Uncharacterized protein.	Checkpoint kinase 2-like protein.	0.719
A0A162NCC9	A0A162NM20	A0A162NCC9	A0A162NM20	Histone H2B; Belongs to the histone H2B family.	Homeodomain-like DNA binding domain-containing transcription factor.	0.861
A0A162NCC9	A0A162Q3V1	A0A162NCC9	A0A162Q3V1	Histone H2B; Belongs to the histone H2B family.	Uncharacterized protein.	0.617
A0A162NCC9	A0A162T215	A0A162NCC9	A0A162T215	Histone H2B; Belongs to the histone H2B family.	Mre11_DNA_bind domain-containing protein; Belongs to the MRE11/RAD32 family.	0.686
A0A162NCC9	A0A162TKK7	A0A162NCC9	A0A162TKK7	Histone H2B; Belongs to the histone H2B family.	Homeodomain-like DNA binding domain-containing transcription factor.	0.861
A0A162NCC9	A0A162YCM2	A0A162NCC9	A0A162YCM2	Histone H2B; Belongs to the histone H2B family.	AAA_23 domain-containing protein.	0.617