(18 nodes) Valine, leucine and isoleucine biosynthesis network (Phycomyces blakesleeanus)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

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Your Input:
	leuC	3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. (373 aa)
	A0A167MVP7	Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (396 aa)
	A0A167NQ90	ACT domain-containing protein. (292 aa)
	A0A167PCB8	Uncharacterized protein. (586 aa)
	A0A167PZ10	DUF1752 domain-containing protein. (243 aa)
	A0A162NB69	Acetolactate synthase. (599 aa)
	A0A162NH17	DUF1752 domain-containing protein. (255 aa)
	A0A162T8R5	PALP domain-containing protein. (417 aa)
	A0A162TFK9	Uncharacterized protein. (233 aa)
	A0A167QT76	DUF1752 domain-containing protein. (301 aa)
	A0A167QJL2	Threonine dehydratase. (527 aa)
	A0A167Q793	DUF1752 domain-containing protein. (380 aa)
	A0A162TQH7	PALP domain-containing protein. (327 aa)
	A0A162UAF9	Uncharacterized protein. (355 aa)
	A0A162NBE3	Uncharacterized protein. (594 aa)
	A0A162XLY4	Uncharacterized protein; Belongs to the ketol-acid reductoisomerase family. (397 aa)
	leu1	3-isopropylmalate dehydratase; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (754 aa)
	A0A163DJZ0	Uncharacterized protein. (346 aa)

Your Current Organism:

Phycomyces blakesleeanus

NCBI taxonomy Id: 763407
Other names: P. blakesleeanus NRRL 1555(-), Phycomyces blakesleeanus NRRL 1555(-)

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A162NB69	A0A162NBE3	A0A162NB69	A0A162NBE3	Acetolactate synthase.	Uncharacterized protein.	0.924
A0A162NB69	A0A162NH17	A0A162NB69	A0A162NH17	Acetolactate synthase.	DUF1752 domain-containing protein.	0.770
A0A162NB69	A0A162T8R5	A0A162NB69	A0A162T8R5	Acetolactate synthase.	PALP domain-containing protein.	0.882
A0A162NB69	A0A162TFK9	A0A162NB69	A0A162TFK9	Acetolactate synthase.	Uncharacterized protein.	0.770
A0A162NB69	A0A162TQH7	A0A162NB69	A0A162TQH7	Acetolactate synthase.	PALP domain-containing protein.	0.863
A0A162NB69	A0A162UAF9	A0A162NB69	A0A162UAF9	Acetolactate synthase.	Uncharacterized protein.	0.895
A0A162NB69	A0A162XLY4	A0A162NB69	A0A162XLY4	Acetolactate synthase.	Uncharacterized protein; Belongs to the ketol-acid reductoisomerase family.	0.935
A0A162NB69	A0A163DJZ0	A0A162NB69	A0A163DJZ0	Acetolactate synthase.	Uncharacterized protein.	0.895
A0A162NB69	A0A167MVP7	A0A162NB69	A0A167MVP7	Acetolactate synthase.	Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.	0.921
A0A162NB69	A0A167NQ90	A0A162NB69	A0A167NQ90	Acetolactate synthase.	ACT domain-containing protein.	0.998
A0A162NB69	A0A167PCB8	A0A162NB69	A0A167PCB8	Acetolactate synthase.	Uncharacterized protein.	0.922
A0A162NB69	A0A167PZ10	A0A162NB69	A0A167PZ10	Acetolactate synthase.	DUF1752 domain-containing protein.	0.761
A0A162NB69	A0A167Q793	A0A162NB69	A0A167Q793	Acetolactate synthase.	DUF1752 domain-containing protein.	0.770
A0A162NB69	A0A167QJL2	A0A162NB69	A0A167QJL2	Acetolactate synthase.	Threonine dehydratase.	0.913
A0A162NB69	A0A167QT76	A0A162NB69	A0A167QT76	Acetolactate synthase.	DUF1752 domain-containing protein.	0.770
A0A162NB69	leu1	A0A162NB69	A0A162YCZ6	Acetolactate synthase.	3-isopropylmalate dehydratase; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate.	0.918
A0A162NB69	leuC	A0A162NB69	A0A167MGI0	Acetolactate synthase.	3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.	0.823
A0A162NBE3	A0A162NB69	A0A162NBE3	A0A162NB69	Uncharacterized protein.	Acetolactate synthase.	0.924
A0A162NBE3	A0A162NH17	A0A162NBE3	A0A162NH17	Uncharacterized protein.	DUF1752 domain-containing protein.	0.536
A0A162NBE3	A0A162T8R5	A0A162NBE3	A0A162T8R5	Uncharacterized protein.	PALP domain-containing protein.	0.709