(30 nodes) Base excision repair network (Phycomyces blakesleeanus)

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Your Input:
	A0A167MI72	DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2213 aa)
	A0A162NBQ7	Transcription factor CBF. (89 aa)
	A0A162PJC2	FPG_CAT domain-containing protein. (382 aa)
	A0A162PLZ4	UDG domain-containing protein. (201 aa)
	UNG1	Uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine. (224 aa)
	A0A162Q3Y5	Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (183 aa)
	A0A162Q4N2	XPGI domain-containing protein. (152 aa)
	A0A162Q5T4	Uncharacterized protein. (503 aa)
	A0A162THI0	Transcription factor TFIID, C-terminal. (364 aa)
	A0A162U944	DNA ligase. (639 aa)
	A0A162U9H3	Uncharacterized protein. (422 aa)
	A0A162XGQ2	Vezatin domain-containing protein. (595 aa)
	A0A162XIN6	Uncharacterized protein. (264 aa)
	A0A162XPX5	Uncharacterized protein. (241 aa)
	A0A162ZDI4	PARP-type domain-containing protein. (235 aa)
	A0A163D1U8	DNA polymerase. (1072 aa)
	A0A163DJH1	Uncharacterized protein. (406 aa)
	A0A163DU75	SRP40_C domain-containing protein. (75 aa)
	A0A163ERS1	ENDO3c domain-containing protein. (306 aa)
	A0A167KHZ5	Uncharacterized protein. (430 aa)
	A0A167KUM1	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (259 aa)
	A0A167L7C6	Uncharacterized protein; Belongs to the MT-A70-like family. (237 aa)
	A0A167LYT8	DNA-(apurinic or apyrimidinic site) lyase; Belongs to the DNA repair enzymes AP/ExoA family. (319 aa)
	A0A167NA25	Poly [ADP-ribose] polymerase. (97 aa)
	FEN1	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] (375 aa)
	A0A167R7K1	DNA_pol_E_B domain-containing protein. (438 aa)
	NTH1	Endonuclease III homolog; Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines; Belongs to the Nth/MutY family. (319 aa)
	A0A167QMF1	XPGN domain-containing protein. (430 aa)
	A0A167PRE9	DNA-(apurinic or apyrimidinic site) lyase; Belongs to the DNA repair enzymes AP/ExoA family. (411 aa)
	A0A167PC19	Vezatin domain-containing protein. (595 aa)

Your Current Organism:

Phycomyces blakesleeanus

NCBI taxonomy Id: 763407
Other names: P. blakesleeanus NRRL 1555(-), Phycomyces blakesleeanus NRRL 1555(-)

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A162NBQ7	A0A163D1U8	A0A162NBQ7	A0A163D1U8	Transcription factor CBF.	DNA polymerase.	0.498
A0A162NBQ7	A0A167MI72	A0A162NBQ7	A0A167MI72	Transcription factor CBF.	DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family.	0.815
A0A162NBQ7	A0A167R7K1	A0A162NBQ7	A0A167R7K1	Transcription factor CBF.	DNA_pol_E_B domain-containing protein.	0.772
A0A162PJC2	A0A162PLZ4	A0A162PJC2	A0A162PLZ4	FPG_CAT domain-containing protein.	UDG domain-containing protein.	0.453
A0A162PJC2	A0A162Q4N2	A0A162PJC2	A0A162Q4N2	FPG_CAT domain-containing protein.	XPGI domain-containing protein.	0.630
A0A162PJC2	A0A162Q5T4	A0A162PJC2	A0A162Q5T4	FPG_CAT domain-containing protein.	Uncharacterized protein.	0.419
A0A162PJC2	A0A162U944	A0A162PJC2	A0A162U944	FPG_CAT domain-containing protein.	DNA ligase.	0.419
A0A162PJC2	A0A162XGQ2	A0A162PJC2	A0A162XGQ2	FPG_CAT domain-containing protein.	Vezatin domain-containing protein.	0.403
A0A162PJC2	A0A167KUM1	A0A162PJC2	A0A167KUM1	FPG_CAT domain-containing protein.	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	0.403
A0A162PJC2	A0A167LYT8	A0A162PJC2	A0A167LYT8	FPG_CAT domain-containing protein.	DNA-(apurinic or apyrimidinic site) lyase; Belongs to the DNA repair enzymes AP/ExoA family.	0.455
A0A162PJC2	A0A167PC19	A0A162PJC2	A0A167PC19	FPG_CAT domain-containing protein.	Vezatin domain-containing protein.	0.403
A0A162PJC2	A0A167PRE9	A0A162PJC2	A0A167PRE9	FPG_CAT domain-containing protein.	DNA-(apurinic or apyrimidinic site) lyase; Belongs to the DNA repair enzymes AP/ExoA family.	0.455
A0A162PJC2	A0A167QMF1	A0A162PJC2	A0A167QMF1	FPG_CAT domain-containing protein.	XPGN domain-containing protein.	0.630
A0A162PJC2	FEN1	A0A162PJC2	A0A167P3U0	FPG_CAT domain-containing protein.	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]	0.630
A0A162PJC2	NTH1	A0A162PJC2	A0A167R1T7	FPG_CAT domain-containing protein.	Endonuclease III homolog; Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines; Belongs to the Nth/MutY family.	0.832
A0A162PJC2	UNG1	A0A162PJC2	A0A162Q1V3	FPG_CAT domain-containing protein.	Uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.	0.517
A0A162PLZ4	A0A162PJC2	A0A162PLZ4	A0A162PJC2	UDG domain-containing protein.	FPG_CAT domain-containing protein.	0.453
A0A162PLZ4	A0A162THI0	A0A162PLZ4	A0A162THI0	UDG domain-containing protein.	Transcription factor TFIID, C-terminal.	0.446
A0A162PLZ4	A0A167LYT8	A0A162PLZ4	A0A167LYT8	UDG domain-containing protein.	DNA-(apurinic or apyrimidinic site) lyase; Belongs to the DNA repair enzymes AP/ExoA family.	0.801
A0A162PLZ4	A0A167PRE9	A0A162PLZ4	A0A167PRE9	UDG domain-containing protein.	DNA-(apurinic or apyrimidinic site) lyase; Belongs to the DNA repair enzymes AP/ExoA family.	0.801