53 items (Mixia osmundae) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

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co-expression

protein homology

Your Input:
	Mo03337	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit OST2; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the [...] (141 aa)
	Mo06768	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (176 aa)
	Mo06448	Uncharacterized protein. (460 aa)
	Mo06410	Uncharacterized protein. (1667 aa)
	Mo06162	Uncharacterized protein. (469 aa)
	Mo06144	Cyanate hydratase; Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide; Belongs to the cyanase family. (162 aa)
	Mo06111	Uncharacterized protein. (442 aa)
	Mo06043	TPR_REGION domain-containing protein. (293 aa)
	Mo05932	GPI-anchor transamidase; Mediates GPI anchoring in the endoplasmic reticulum, by replacing a protein's C-terminal GPI attachment signal peptide with a pre-assembled GPI. During this transamidation reaction, the GPI transamidase forms a carbonyl intermediate with the substrate protein. Belongs to the peptidase C13 family. (313 aa)
	Mo06275	Uncharacterized protein. (796 aa)
	Mo06246	Uncharacterized protein. (797 aa)
	Mo06189	GPI mannosyltransferase 1; Mannosyltransferase involved in glycosylphosphatidylinositol- anchor biosynthesis. Transfers the first alpha-1,4-mannose to GlcN- acyl-PI during GPI precursor assembly. Required for cell wall integrity. (403 aa)
	Mo05758	TPR_REGION domain-containing protein. (240 aa)
	Mo05609	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit WBP1; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the [...] (423 aa)
	Mo05608	EMC1_C domain-containing protein. (854 aa)
	Mo05602	Uncharacterized protein. (624 aa)
	Mo05568	Uncharacterized protein; Belongs to the heat shock protein 70 family. (689 aa)
	Mo05079	Aminotran_1_2 domain-containing protein. (532 aa)
	Mo05034	J domain-containing protein. (666 aa)
	Mo04564	Maintenance of mitochondrial morphology protein 1; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. The MDM12-MMM1 subcomplex functions in the major beta-barrel assembly pathway that is responsible for biogenesis of all outer membrane beta- barrel proteins, and acts in a late step after the SAM complex. The MDM10-MDM12-MMM1 su [...] (539 aa)
	Mo04229	Aminotran_1_2 domain-containing protein. (706 aa)
	Mo04138	UDP-N-acetylglucosamine transferase subunit ALG14; Involved in protein N-glycosylation. Essential for the second step of the dolichol-linked oligosaccharide pathway. Anchors the catalytic subunit ALG13 to the ER. (291 aa)
	Mo04073	ER membrane protein complex subunit 3; The EMC seems to be required for efficient folding of proteins in the endoplasmic reticulum (ER). Belongs to the EMC3 family. (266 aa)
	Mo03766	Mitochondrial distribution and morphology protein 10; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis and may function in phospholipid exchange. MDM10 is involved in the late assembly steps of the general translocase of the mitochondrial outer membrane (TOM complex). Functions in the TOM40-specific route of the assembly of outer membrane beta-barrel proteins, including the association of TOM40 with the recepto [...] (415 aa)
	Mo03637	Mitochondrial distribution and morphology protein 34; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. Mo03637 is required for the interaction of the ER-resident membrane protein MMM1 and the outer mitochondrial membrane-resident beta-barrel protein MDM10; Belongs to the MDM34 family. (586 aa)
	Mo03633	RING-type domain-containing protein. (680 aa)
	Mo03419	Uncharacterized protein. (814 aa)
	Mo00038	BHLH domain-containing protein. (2122 aa)
	Mo00091	Uncharacterized protein. (170 aa)
	Mo00112	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the en [...] (500 aa)
	Mo00264	RanBP2-type domain-containing protein. (703 aa)
	Mo00693	Uncharacterized protein. (128 aa)
	Mo00735	Uncharacterized protein. (515 aa)
	Mo00799	Uncharacterized protein. (112 aa)
	Mo00836	Uncharacterized protein. (655 aa)
	Mo00913	Uncharacterized protein. (399 aa)
	Mo00925	Uncharacterized protein. (330 aa)
	Mo01335	Uncharacterized protein. (1146 aa)
	Mo01354	Uncharacterized protein. (213 aa)
	Mo01403	Signal peptidase subunit 3. (184 aa)
	Mo01662	Uncharacterized protein. (301 aa)
	Mo01755	Uncharacterized protein. (317 aa)
	Mo01921	SRP54 domain-containing protein. (985 aa)
	Mo02101	Uncharacterized protein; Belongs to the AAA ATPase family. (877 aa)
	Mo02132	Uncharacterized protein. (194 aa)
	Mo02226	ER membrane protein complex subunit 4; Belongs to the EMC4 family. (199 aa)
	Mo02306	Uncharacterized protein. (549 aa)
	Mo02510	Uncharacterized protein. (1090 aa)
	Mo02541	Uncharacterized protein. (131 aa)
	Mo02657	DUF2012 domain-containing protein. (239 aa)
	Mo02833	Protein GET1; Required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum. Acts as a membrane receptor for soluble GET3, which recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. (212 aa)
	Mo03131	Uncharacterized protein. (284 aa)
	Mo03360	Uncharacterized protein. (290 aa)

Your Current Organism:

Mixia osmundae

NCBI taxonomy Id: 764103
Other names: M. osmundae IAM 14324, Mixia osmundae IAM 14324

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Mo00038	Mo00112	G7DS37	G7DSB1	BHLH domain-containing protein.	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the en [...]	0.467
Mo00038	Mo01755	G7DS37	G7DX03	BHLH domain-containing protein.	Uncharacterized protein.	0.792
Mo00038	Mo02510	G7DS37	G7DZ43	BHLH domain-containing protein.	Uncharacterized protein.	0.541
Mo00038	Mo05568	G7DS37	G7E7S0	BHLH domain-containing protein.	Uncharacterized protein; Belongs to the heat shock protein 70 family.	0.605
Mo00038	Mo05609	G7DS37	G7E7W1	BHLH domain-containing protein.	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit WBP1; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the [...]	0.575
Mo00038	Mo06246	G7DS37	G7E8S7	BHLH domain-containing protein.	Uncharacterized protein.	0.459
Mo00091	Mo00836	G7DS90	G7DUC8	Uncharacterized protein.	Uncharacterized protein.	0.890
Mo00091	Mo01662	G7DS90	G7DWR0	Uncharacterized protein.	Uncharacterized protein.	0.898
Mo00091	Mo02306	G7DS90	G7DYJ0	Uncharacterized protein.	Uncharacterized protein.	0.475
Mo00091	Mo05602	G7DS90	G7E7V4	Uncharacterized protein.	Uncharacterized protein.	0.523
Mo00091	Mo05932	G7DS90	G7E9B9	Uncharacterized protein.	GPI-anchor transamidase; Mediates GPI anchoring in the endoplasmic reticulum, by replacing a protein's C-terminal GPI attachment signal peptide with a pre-assembled GPI. During this transamidation reaction, the GPI transamidase forms a carbonyl intermediate with the substrate protein. Belongs to the peptidase C13 family.	0.469
Mo00091	Mo06189	G7DS90	G7E8M1	Uncharacterized protein.	GPI mannosyltransferase 1; Mannosyltransferase involved in glycosylphosphatidylinositol- anchor biosynthesis. Transfers the first alpha-1,4-mannose to GlcN- acyl-PI during GPI precursor assembly. Required for cell wall integrity.	0.543
Mo00091	Mo06448	G7DS90	G7EA85	Uncharacterized protein.	Uncharacterized protein.	0.788
Mo00112	Mo00038	G7DSB1	G7DS37	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the en [...]	BHLH domain-containing protein.	0.467
Mo00112	Mo01335	G7DSB1	G7DVS2	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the en [...]	Uncharacterized protein.	0.997
Mo00112	Mo01755	G7DSB1	G7DX03	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the en [...]	Uncharacterized protein.	0.998
Mo00112	Mo03337	G7DSB1	G7E1F6	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the en [...]	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit OST2; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the [...]	0.998
Mo00112	Mo03360	G7DSB1	G7E1H9	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the en [...]	Uncharacterized protein.	0.465
Mo00112	Mo05034	G7DSB1	G7E688	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the en [...]	J domain-containing protein.	0.414
Mo00112	Mo05568	G7DSB1	G7E7S0	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the en [...]	Uncharacterized protein; Belongs to the heat shock protein 70 family.	0.614