STRINGSTRING
fhs_1 fhs_1 EHI70623.1 EHI70623.1 EHI70607.1 EHI70607.1 EHI70609.1 EHI70609.1 rpmE rpmE EHI70602.1 EHI70602.1 EHI70673.1 EHI70673.1 EHI70652.1 EHI70652.1 rplS rplS EHI70605.1 EHI70605.1 EHI70677.1 EHI70677.1 EHI70604.1 EHI70604.1 ychF ychF EHI70521.1 EHI70521.1 guaB guaB recF recF dnaB dnaB rpsD rpsD rpmG rpmG rpmF rpmF EHI70556.1 EHI70556.1 rpsJ rpsJ rplC rplC rplD rplD rplW rplW rplB rplB rpsS rpsS rplV rplV rpsC rpsC rplP rplP rpmC rpmC rpsQ rpsQ rplN rplN rplX rplX rplE rplE rpsN_1 rpsN_1 rpsH rpsH rplF rplF rplR rplR rpsE rpsE rpmD rpmD rplO rplO adk adk rpmJ rpmJ rpsM rpsM rpsK rpsK rplQ rplQ EHI70435.1 EHI70435.1 EHI70353.1 EHI70353.1 EHI70354.1 EHI70354.1 EHI70411.1 EHI70411.1 EHI70415.1 EHI70415.1 EHI70390.1 EHI70390.1 EHI68626.1 EHI68626.1 EHI68619.1 EHI68619.1 recN recN hup hup recR recR cshA cshA EHI68706.1 EHI68706.1 udk udk EHI68665.1 EHI68665.1 EHI68584.1 EHI68584.1 EHI68607.1 EHI68607.1 EHI68686.1 EHI68686.1 rnz rnz EHI68767.1 EHI68767.1 EHI68622.1 EHI68622.1 nth nth EHI68594.1 EHI68594.1 EHI70752.1 EHI70752.1 EHI70910.1 EHI70910.1 mgtA mgtA EHI70920.1 EHI70920.1 EHI70865.1 EHI70865.1 EHI70771.1 EHI70771.1 EHI70976.1 EHI70976.1 EHI70921.1 EHI70921.1 EHI70834.1 EHI70834.1 EHI70890.1 EHI70890.1 EHI70999.1 EHI70999.1 dtd dtd rpsO rpsO mrnC mrnC EHI70892.1 EHI70892.1 trxA trxA rpsF rpsF rpsR rpsR EHI70770.1 EHI70770.1 EHI70975.1 EHI70975.1 fabF fabF EHI70715.1 EHI70715.1 EHI69587.1 EHI69587.1 EHI69864.1 EHI69864.1 acoB acoB EHI69810.1 EHI69810.1 EHI69499.1 EHI69499.1 parE parE rpsA rpsA EHI69450.1 EHI69450.1 ribF ribF rpsT rpsT EHI69704.1 EHI69704.1 EHI69561.1 EHI69561.1 EHI69341.1 EHI69341.1 EHI69569.1 EHI69569.1 EHI69712.1 EHI69712.1 EHI69932.1 EHI69932.1 ylqF ylqF topA topA EHI69487.1 EHI69487.1 EHI69674.1 EHI69674.1 EHI69721.1 EHI69721.1 radC radC folK folK rplL rplL rplJ rplJ EHI69506.1 EHI69506.1 EHI69713.1 EHI69713.1 fni fni rpsP rpsP EHI69709.1 EHI69709.1 rpmA rpmA rplU rplU EHI69659.1 EHI69659.1 rplT rplT rpmI rpmI dnaG dnaG rpsU rpsU ezrA ezrA gyrB gyrB EHI69079.1 EHI69079.1 EHI69322.1 EHI69322.1 EHI69257.1 EHI69257.1 EHI69170.1 EHI69170.1 cshB cshB priA priA EHI68829.1 EHI68829.1 raiA raiA ispE ispE tyrS tyrS ackA ackA EHI69069.1 EHI69069.1 EHI69212.1 EHI69212.1 EHI68868.1 EHI68868.1 rpmH rpmH EHI69166.1 EHI69166.1 rnmV rnmV rpsL rpsL rpsG rpsG rpsN_2 rpsN_2 EHI69169.1 EHI69169.1 rplM rplM rpsI rpsI EHI68809.1 EHI68809.1 truA truA rpmB rpmB sufC sufC sufD sufD sufB sufB recO recO purF purF purD purD EHI69103.1 EHI69103.1 EHI69047.1 EHI69047.1 EHI68866.1 EHI68866.1 rpsB rpsB EHI69315.1 EHI69315.1 EHI69248.1 EHI69248.1 hutG hutG fhs_2 fhs_2 EHI68824.1 EHI68824.1 ftcD ftcD EHI68807.1 EHI68807.1 EHI69246.1 EHI69246.1 yqeH yqeH nadD nadD EHI70021.1 EHI70021.1 EHI70082.1 EHI70082.1 EHI70199.1 EHI70199.1 EHI70108.1 EHI70108.1 EHI70026.1 EHI70026.1 EHI70134.1 EHI70134.1 cutC cutC serC serC EHI70030.1 EHI70030.1 lctO lctO EHI69981.1 EHI69981.1 rplK rplK rplA rplA ybeY ybeY EHI70089.1 EHI70089.1 EHI70193.1 EHI70193.1 EHI70123.1 EHI70123.1 EHI69976.1 EHI69976.1 smc smc EHI69986.1 EHI69986.1 EHI70156.1 EHI70156.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
fhs_1Formate--tetrahydrofolate ligase; Belongs to the formate--tetrahydrofolate ligase family. (556 aa)
EHI70623.1Putative calcium-translocating P-type ATPase, PMCA-type. (893 aa)
EHI70607.1Carbohydrate kinase, PfkB family. (333 aa)
EHI70609.1Putative dipeptidase B. (465 aa)
rpmERibosomal protein L31. (86 aa)
EHI70602.1DHHA1 domain protein. (312 aa)
EHI70673.1Acetyltransferase, GNAT family. (143 aa)
EHI70652.1adenosine/AMP deaminase; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain one or more premature stops and/or frameshifts. (243 aa)
rplSRibosomal protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site. (115 aa)
EHI70605.1Hypothetical protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a premature stop. (85 aa)
EHI70677.1Hypothetical protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a premature stop. (117 aa)
EHI70604.1Nucleoside triphosphatase, D5 family. (491 aa)
ychFGTP-binding protein YchF; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner. (371 aa)
EHI70521.1ParB-like protein; Belongs to the ParB family. (257 aa)
guaBInosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. (493 aa)
recFDNA replication and repair protein RecF; The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP; Belongs to the RecF family. (364 aa)
dnaBReplicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. (453 aa)
rpsDRibosomal protein S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit. (203 aa)
rpmGRibosomal protein L33; Belongs to the bacterial ribosomal protein bL33 family. (49 aa)
rpmFRibosomal protein L32; Belongs to the bacterial ribosomal protein bL32 family. (60 aa)
EHI70556.1RNAse H domain protein, YqgF family; Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA; Belongs to the YqgF HJR family. (139 aa)
rpsJRibosomal protein S10; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family. (102 aa)
rplC50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family. (208 aa)
rplD50S ribosomal protein L4; Forms part of the polypeptide exit tunnel. (207 aa)
rplWRibosomal protein L23; One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome; Belongs to the universal ribosomal protein uL23 family. (98 aa)
rplBRibosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family. (277 aa)
rpsSRibosomal protein S19; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA. (92 aa)
rplVRibosomal protein L22; The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome. (114 aa)
rpsCRibosomal protein S3; Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation; Belongs to the universal ribosomal protein uS3 family. (217 aa)
rplPRibosomal protein L16; Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs; Belongs to the universal ribosomal protein uL16 family. (137 aa)
rpmCRibosomal protein L29; Belongs to the universal ribosomal protein uL29 family. (68 aa)
rpsQ30S ribosomal protein S17; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA. (86 aa)
rplNRibosomal protein L14; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family. (122 aa)
rplXRibosomal protein L24; One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit. (101 aa)
rplE50S ribosomal protein L5; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs. (180 aa)
rpsN_1Ribosomal protein S14p/S29e; Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site. (61 aa)
rpsHRibosomal protein S8; One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; Belongs to the universal ribosomal protein uS8 family. (132 aa)
rplFRibosomal protein L6; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family. (178 aa)
rplRRibosomal protein L18; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. (118 aa)
rpsERibosomal protein S5; Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body. Belongs to the universal ribosomal protein uS5 family. (164 aa)
rpmDRibosomal protein L30. (60 aa)
rplORibosomal protein L15; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family. (146 aa)
adkAdenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (213 aa)
rpmJRibosomal protein L36; Belongs to the bacterial ribosomal protein bL36 family. (38 aa)
rpsM30S ribosomal protein S13; Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites. Belongs to the universal ribosomal protein uS13 family. (121 aa)
rpsK30S ribosomal protein S11; Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine- Dalgarno cleft in the 70S ribosome; Belongs to the universal ribosomal protein uS11 family. (127 aa)
rplQRibosomal protein L17. (128 aa)
EHI70435.1FR47-like protein. (146 aa)
EHI70353.1Cytochrome C biogenesis protein transmembrane region. (236 aa)
EHI70354.1Hypothetical protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift. (416 aa)
EHI70411.1Glycosyl hydrolase family 38, N-terminal domain protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a premature stop. (612 aa)
EHI70415.1Glycosyl hydrolase family 38 C-terminal domain protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a premature stop. (276 aa)
EHI70390.1Hypothetical protein. (175 aa)
EHI68626.1S4 domain protein. (263 aa)
EHI68619.1Polyprenyl synthetase; Belongs to the FPP/GGPP synthase family. (290 aa)
recNDNA repair protein RecN; May be involved in recombinational repair of damaged DNA. (553 aa)
hupDNA-binding protein HU; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions. (91 aa)
recRRecombination protein RecR; May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO. (198 aa)
cshADEAD/DEAH box helicase; DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA-dependent ATPase activity; Belongs to the DEAD box helicase family. CshA subfamily. (569 aa)
EHI68706.1Type III restriction enzyme, res subunit. (365 aa)
udkUridine kinase. (208 aa)
EHI68665.1Leucine rich repeat protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a premature stop. (484 aa)
EHI68584.1Carbohydrate kinase, PfkB family; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift. (199 aa)
EHI68607.1Carbohydrate kinase, PfkB domain protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift. (122 aa)
EHI68686.1FR47-like protein. (148 aa)
rnzRibonuclease Z; Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA; Belongs to the RNase Z family. (309 aa)
EHI68767.1KR domain protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (254 aa)
EHI68622.1Replication initiation and membrane attachment protein, DnaB/DnaD family. (226 aa)
nthEndonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. (216 aa)
EHI68594.1Replication initiator protein A, N-terminal domain protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift. (164 aa)
EHI70752.1Acetyltransferase, GNAT domain protein. (92 aa)
EHI70910.1Peptidase, C69 family. (495 aa)
mgtAMagnesium-importing ATPase. (884 aa)
EHI70920.1Putative L-ribulose-5-phosphate 4-epimerase. (238 aa)
EHI70865.1Hypothetical protein. (363 aa)
EHI70771.1Metallo-beta-lactamase domain protein. (259 aa)
EHI70976.1Peptidase, S54 family. (224 aa)
EHI70921.1Recombination factor protein RarA. (423 aa)
EHI70834.1PTS system IIBC component; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift. (422 aa)
EHI70890.1PTS system glucose-specific EIICBA component family protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift. (55 aa)
EHI70999.1Hypothetical protein. (184 aa)
dtdD-tyrosyl-tRNA(Tyr) deacylase; An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA- based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D- aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl- tRNA entities in vivo and helps enforce protein L-homochirality. Belongs to the DTD family. (147 aa)
rpsORibosomal protein S15; Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome. (89 aa)
mrnCRNase3 domain protein; Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc); Rnc processes 30S rRNA into smaller rRNA precursors; Belongs to the MrnC RNase family. (132 aa)
EHI70892.1Acetyltransferase, GNAT family. (145 aa)
trxAThioredoxin; Belongs to the thioredoxin family. (104 aa)
rpsFRibosomal protein S6; Binds together with S18 to 16S ribosomal RNA. (96 aa)
rpsRRibosomal protein S18; Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit; Belongs to the bacterial ribosomal protein bS18 family. (79 aa)
EHI70770.1Putative ComE operon protein 2. (151 aa)
EHI70975.1PTS system sucrose-specific IIBC component. (635 aa)
fabFBeta-ketoacyl-acyl-carrier-protein synthase II; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. (410 aa)
EHI70715.1Replication initiator protein A, N-terminal domain protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift. (164 aa)
EHI69587.1Hypothetical protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift. (349 aa)
EHI69864.1Dehydrogenase E1 component. (322 aa)
acoBTPP-dependent acetoin dehydrogenase complex, E1 component, beta subunit. (332 aa)
EHI69810.1Hypothetical protein. (447 aa)
EHI69499.1Ornithine cyclodeaminase. (331 aa)
parEDNA topoisomerase IV, B subunit; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule. (649 aa)
rpsA30S ribosomal protein S1. (401 aa)
EHI69450.1Cation diffusion facilitator family transporter; Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. (402 aa)
ribFRiboflavin biosynthesis protein RibF; Belongs to the ribF family. (310 aa)
rpsTRibosomal protein S20; Binds directly to 16S ribosomal RNA. (77 aa)
EHI69704.13-hydroxyacyl-CoA dehydrogenase, NAD binding domain protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a premature stop. (248 aa)
EHI69561.1enoyl-CoA hydratase/isomerase domain protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a premature stop. (311 aa)
EHI69341.1Hypothetical protein. (292 aa)
EHI69569.1Replication initiator protein A, N-terminal domain protein. (169 aa)
EHI69712.1Hypothetical protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a premature stop. (175 aa)
EHI69932.1Hypothetical protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a premature stop. (185 aa)
ylqFRibosome biogenesis GTP-binding protein YlqF; Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity; Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily. (282 aa)
topADNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] (711 aa)
EHI69487.1Hypothetical protein. (237 aa)
EHI69674.1ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift. (319 aa)
EHI69721.1Aminotransferase, class V. (374 aa)
radCDNA repair protein RadC; Belongs to the UPF0758 family. (226 aa)
folK2-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase. (164 aa)
rplLRibosomal protein L7/L12; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation; Belongs to the bacterial ribosomal protein bL12 family. (121 aa)
rplJRibosomal protein L10; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family. (167 aa)
EHI69506.1hydroxymethylglutaryl-CoA synthase. (393 aa)
EHI69713.1hydroxymethylglutaryl-CoA reductase, degradative; Belongs to the HMG-CoA reductase family. (426 aa)
fniIsopentenyl-diphosphate delta-isomerase, type 2; Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP). (330 aa)
rpsPRibosomal protein S16; Belongs to the bacterial ribosomal protein bS16 family. (90 aa)
EHI69709.1Efflux transporter, RND family, MFP subunit. (421 aa)
rpmARibosomal protein L27; Belongs to the bacterial ribosomal protein bL27 family. (97 aa)
rplURibosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family. (104 aa)
EHI69659.1Aminotransferase, class V. (380 aa)
rplTRibosomal protein L20; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit. (119 aa)
rpmIRibosomal protein L35; Belongs to the bacterial ribosomal protein bL35 family. (65 aa)
dnaGDNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. (603 aa)
rpsURibosomal protein S21; Belongs to the bacterial ribosomal protein bS21 family. (58 aa)
ezrASeptation ring formation regulator EzrA; Negative regulator of FtsZ ring formation; modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization; Belongs to the EzrA family. (574 aa)
gyrBDNA gyrase, B subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. (650 aa)
EHI69079.1Ribosomal protein L7Ae. (100 aa)
EHI69322.1Hydrolase, alpha/beta domain protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift. (117 aa)
EHI69257.1Hypothetical protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain one or more premature stops and/or frameshifts. (100 aa)
EHI69170.1Hypothetical protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a premature stop. (77 aa)
cshBDEAD/DEAH box helicase; Probable DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures. (447 aa)
priAPrimosomal protein N; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily. (796 aa)
EHI68829.1S1 RNA binding domain protein. (120 aa)
raiARibosomal subunit interface protein; Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth. (182 aa)
ispE4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. (266 aa)
tyrStyrosine--tRNA ligase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily. (418 aa)
ackAAcetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (397 aa)
EHI69069.1dTMP kinase-like protein. (213 aa)
EHI69212.1TIM-barrel protein, nifR3 family; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family. (325 aa)
EHI68868.1Putative endoribonuclease L-PSP. (120 aa)
rpmHRibosomal protein L34; Belongs to the bacterial ribosomal protein bL34 family. (44 aa)
EHI69166.1Hypothetical protein. (216 aa)
rnmVRibonuclease M5; Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step. (190 aa)
rpsLRibosomal protein S12; Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit. (137 aa)
rpsGRibosomal protein S7; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA; Belongs to the universal ribosomal protein uS7 family. (156 aa)
rpsN_2Ribosomal protein S14p/S29e; Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site; Belongs to the universal ribosomal protein uS14 family. (89 aa)
EHI69169.1DNA-binding protein, YbaB/EbfC family; Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection. (99 aa)
rplMRibosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. (148 aa)
rpsIRibosomal protein S9; Belongs to the universal ribosomal protein uS9 family. (130 aa)
EHI68809.1Hypothetical protein. (95 aa)
truAtRNA pseudouridine synthase A; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs. (249 aa)
rpmBRibosomal protein L28; Belongs to the bacterial ribosomal protein bL28 family. (62 aa)
sufCFeS assembly ATPase SufC. (256 aa)
sufDFeS assembly protein SufD. (420 aa)
sufBFeS assembly protein SufB. (472 aa)
recODNA repair protein RecO; Involved in DNA repair and RecF pathway recombination. (264 aa)
purFAmidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. (484 aa)
purDPhosphoribosylamine--glycine ligase; Belongs to the GARS family. (420 aa)
EHI69103.1PTS system, glucose-like IIB component; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a premature stop. (231 aa)
EHI69047.1Phosphoenolpyruvate-dependent sugar PTS family porter, EIIA 1; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a premature stop. (394 aa)
EHI68866.1Transketolase, thiamine pyrophosphate-binding domain protein. (284 aa)
rpsBRibosomal protein S2; Belongs to the universal ribosomal protein uS2 family. (255 aa)
EHI69315.1Hypothetical protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift. (184 aa)
EHI69248.1Hypothetical protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift. (837 aa)
hutGFormimidoylglutamase; Catalyzes the conversion of N-formimidoyl-L-glutamate to L- glutamate and formamide; Belongs to the arginase family. (329 aa)
fhs_2Formate--tetrahydrofolate ligase; Belongs to the formate--tetrahydrofolate ligase family. (550 aa)
EHI68824.1Putative methenyltetrahydrofolate cyclohydrolase. (208 aa)
ftcDGlutamate formimidoyltransferase. (299 aa)
EHI68807.1Hypothetical protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift. (437 aa)
EHI69246.1SNF2 family N-terminal domain protein. (440 aa)
yqeHRibosome biogenesis GTPase YqeH. (372 aa)
nadDNicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). (210 aa)
EHI70021.1Hypothetical protein. (390 aa)
EHI70082.1Primosomal protein DnaI. (300 aa)
EHI70199.1Bacterial SNF2 helicase associated. (1030 aa)
EHI70108.1Acetyltransferase, GNAT family; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift. (152 aa)
EHI70026.1Hypothetical protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift. (321 aa)
EHI70134.1Peptidase, M28 domain protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift. (396 aa)
cutCCutC family protein; Participates in the control of copper homeostasis. Belongs to the CutC family. (209 aa)
serCPhosphoserine transaminase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine. (366 aa)
EHI70030.1methylated-DNA-[protein]-cysteine S-methyltransferase, DNA-binding domain protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift. (153 aa)
lctOL-lactate oxidase. (378 aa)
EHI69981.1Amidohydrolase. (404 aa)
rplKRibosomal protein L11; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. (141 aa)
rplARibosomal protein L1; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release. (229 aa)
ybeYMetalloprotein, YbeY family; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA. (167 aa)
EHI70089.1Prokaryotic diacylglycerol kinase. (135 aa)
EHI70193.1Glutamine cyclotransferase domain protein. (213 aa)
EHI70123.1ABC transporter, ATP-binding protein. (330 aa)
EHI69976.1Metallo-beta-lactamase domain protein. (269 aa)
smcChromosome segregation protein SMC; Required for chromosome condensation and partitioning. Belongs to the SMC family. (1181 aa)
EHI69986.1HD domain protein. (437 aa)
EHI70156.1Replication initiation and membrane attachment protein, DnaB/DnaD family. (129 aa)
Your Current Organism:
Streptococcus ictaluri
NCBI taxonomy Id: 764299
Other names: S. ictaluri 707-05, Streptococcus ictaluri 707-05, Streptococcus ictaluri str. 707-05, Streptococcus ictaluri strain 707-05
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