(11 nodes) Lysosomal microautophagy network (Piloderma croceum)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	A0A0C3G0K9	Lipase_3 domain-containing protein. (417 aa)
	A0A0C3BD42	SPX domain-containing protein. (861 aa)
	A0A0C3BE77	PH domain-containing protein. (695 aa)
	A0A0C3BEL5	Uncharacterized protein; Belongs to the OSBP family. (412 aa)
	A0A0C3F4X9	Lipase_3 domain-containing protein. (364 aa)
	A0A0C3FKN4	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 and ATG8 for its conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Autophagy is essential for maintenance of amino acid levels and protein synthesis under nitrogen starvation. Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy wh [...] (674 aa)
	A0A0C3BWZ5	DUF202 domain-containing protein. (124 aa)
	A0A0C3BLH8	Lipase_3 domain-containing protein. (417 aa)
	A0A0C3FST4	DUF3543 domain-containing protein. (633 aa)
	A0A0C3G5V8	Uncharacterized protein. (2134 aa)
	A0A0C3AX88	Uncharacterized protein; Belongs to the OSBP family. (1157 aa)

Your Current Organism:

Piloderma croceum

NCBI taxonomy Id: 765440
Other names: P. croceum F 1598, Piloderma croceum F 1598

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Browse interactions in tabular form:

node1	node2	node1 annotation	node2 annotation	score
A0A0C3AX88	A0A0C3BD42	Uncharacterized protein; Belongs to the OSBP family.	SPX domain-containing protein.	0.441
A0A0C3AX88	A0A0C3BE77	Uncharacterized protein; Belongs to the OSBP family.	PH domain-containing protein.	0.514
A0A0C3AX88	A0A0C3BEL5	Uncharacterized protein; Belongs to the OSBP family.	Uncharacterized protein; Belongs to the OSBP family.	0.748
A0A0C3AX88	A0A0C3FKN4	Uncharacterized protein; Belongs to the OSBP family.	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 and ATG8 for its conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Autophagy is essential for maintenance of amino acid levels and protein synthesis under nitrogen starvation. Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy wh [...]	0.612
A0A0C3BD42	A0A0C3AX88	SPX domain-containing protein.	Uncharacterized protein; Belongs to the OSBP family.	0.441
A0A0C3BD42	A0A0C3BWZ5	SPX domain-containing protein.	DUF202 domain-containing protein.	0.441
A0A0C3BE77	A0A0C3AX88	PH domain-containing protein.	Uncharacterized protein; Belongs to the OSBP family.	0.514
A0A0C3BE77	A0A0C3BEL5	PH domain-containing protein.	Uncharacterized protein; Belongs to the OSBP family.	0.444
A0A0C3BEL5	A0A0C3AX88	Uncharacterized protein; Belongs to the OSBP family.	Uncharacterized protein; Belongs to the OSBP family.	0.748
A0A0C3BEL5	A0A0C3BE77	Uncharacterized protein; Belongs to the OSBP family.	PH domain-containing protein.	0.444
A0A0C3BLH8	A0A0C3F4X9	Lipase_3 domain-containing protein.	Lipase_3 domain-containing protein.	0.841
A0A0C3BLH8	A0A0C3FKN4	Lipase_3 domain-containing protein.	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 and ATG8 for its conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Autophagy is essential for maintenance of amino acid levels and protein synthesis under nitrogen starvation. Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy wh [...]	0.896
A0A0C3BLH8	A0A0C3FST4	Lipase_3 domain-containing protein.	DUF3543 domain-containing protein.	0.901
A0A0C3BLH8	A0A0C3G0K9	Lipase_3 domain-containing protein.	Lipase_3 domain-containing protein.	0.840
A0A0C3BLH8	A0A0C3G5V8	Lipase_3 domain-containing protein.	Uncharacterized protein.	0.888
A0A0C3BWZ5	A0A0C3BD42	DUF202 domain-containing protein.	SPX domain-containing protein.	0.441
A0A0C3F4X9	A0A0C3BLH8	Lipase_3 domain-containing protein.	Lipase_3 domain-containing protein.	0.841
A0A0C3F4X9	A0A0C3FKN4	Lipase_3 domain-containing protein.	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 and ATG8 for its conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Autophagy is essential for maintenance of amino acid levels and protein synthesis under nitrogen starvation. Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy wh [...]	0.896
A0A0C3F4X9	A0A0C3FST4	Lipase_3 domain-containing protein.	DUF3543 domain-containing protein.	0.901
A0A0C3F4X9	A0A0C3G0K9	Lipase_3 domain-containing protein.	Lipase_3 domain-containing protein.	0.887