(10 nodes) Mitotic DNA integrity checkpoint signaling network (Piloderma croceum)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	A0A0C3G055	MRC1 domain-containing protein. (1432 aa)
	A0A0C3G7L8	Uncharacterized protein. (625 aa)
	A0A0C3AND1	HORMA domain-containing protein. (209 aa)
	A0A0C3BAB6	Uncharacterized protein. (534 aa)
	A0A0C3BFK6	Uncharacterized protein. (983 aa)
	A0A0C3BG59	Protein kinase domain-containing protein. (396 aa)
	A0A0C3F498	Checkpoint protein; Belongs to the HUS1 family. (285 aa)
	A0A0C3FGE8	AAA domain-containing protein. (634 aa)
	A0A0C3FVN9	Uncharacterized protein. (580 aa)
	A0A0C3FYD6	zf-4CXXC_R1 domain-containing protein. (791 aa)

Your Current Organism:

Piloderma croceum

NCBI taxonomy Id: 765440
Other names: P. croceum F 1598, Piloderma croceum F 1598

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 annotation	node2 annotation	score
A0A0C3AND1	A0A0C3BG59	HORMA domain-containing protein.	Protein kinase domain-containing protein.	0.505
A0A0C3AND1	A0A0C3FGE8	HORMA domain-containing protein.	AAA domain-containing protein.	0.640
A0A0C3AND1	A0A0C3FVN9	HORMA domain-containing protein.	Uncharacterized protein.	0.501
A0A0C3AND1	A0A0C3G7L8	HORMA domain-containing protein.	Uncharacterized protein.	0.473
A0A0C3BAB6	A0A0C3BFK6	Uncharacterized protein.	Uncharacterized protein.	0.988
A0A0C3BAB6	A0A0C3BG59	Uncharacterized protein.	Protein kinase domain-containing protein.	0.400
A0A0C3BAB6	A0A0C3F498	Uncharacterized protein.	Checkpoint protein; Belongs to the HUS1 family.	0.994
A0A0C3BAB6	A0A0C3FGE8	Uncharacterized protein.	AAA domain-containing protein.	0.543
A0A0C3BAB6	A0A0C3G055	Uncharacterized protein.	MRC1 domain-containing protein.	0.861
A0A0C3BAB6	A0A0C3G7L8	Uncharacterized protein.	Uncharacterized protein.	0.992
A0A0C3BFK6	A0A0C3BAB6	Uncharacterized protein.	Uncharacterized protein.	0.988
A0A0C3BFK6	A0A0C3BG59	Uncharacterized protein.	Protein kinase domain-containing protein.	0.656
A0A0C3BFK6	A0A0C3F498	Uncharacterized protein.	Checkpoint protein; Belongs to the HUS1 family.	0.900
A0A0C3BFK6	A0A0C3FGE8	Uncharacterized protein.	AAA domain-containing protein.	0.563
A0A0C3BFK6	A0A0C3FVN9	Uncharacterized protein.	Uncharacterized protein.	0.959
A0A0C3BFK6	A0A0C3FYD6	Uncharacterized protein.	zf-4CXXC_R1 domain-containing protein.	0.939
A0A0C3BFK6	A0A0C3G055	Uncharacterized protein.	MRC1 domain-containing protein.	0.463
A0A0C3BFK6	A0A0C3G7L8	Uncharacterized protein.	Uncharacterized protein.	0.934
A0A0C3BG59	A0A0C3AND1	Protein kinase domain-containing protein.	HORMA domain-containing protein.	0.505
A0A0C3BG59	A0A0C3BAB6	Protein kinase domain-containing protein.	Uncharacterized protein.	0.400