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| | hppA | Pyrophosphatase; Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force. (741 aa) |
| | ppa | Inorganic pyrophosphatase; Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions. (179 aa) |
| | clpX | Clp protease ATP-binding protein; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP. (421 aa) |
| | lon | DNA-binding protein; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner. (808 aa) |
| | prfC | Peptide chain release factor 3; Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily. (546 aa) |
| | ALV05961.1 | Pfam:pfam03969 AFG1-like ATPase. (366 aa) |
| | ALV05968.1 | Putative segregation and condensation protein B; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves. (472 aa) |
| | hflX | GTPase HflX; GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family. (420 aa) |
| | recG | Putative ATP-dependent DNA helicase; Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y- DNA); Belongs to the helicase family. RecG subfamily. (732 aa) |
| | apaH | Bis(5'-nucleosyl)-tetraphosphatase, symmetrical; Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP; Belongs to the Ap4A hydrolase family. (276 aa) |
| | ALV06125.1 | Exopolyphosphatase; Pfam:pfam02541 Ppx/GppA phosphatase family. (533 aa) |
| | ALV06151.1 | DNA/RNA helicase, superfamily I; Pfam:pfam13361 UvrD-like helicase C-terminal domain. (821 aa) |
| | ALV06164.1 | Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB; Pfam:pfam00437 Type II/IV secretion system protein. (605 aa) |
| | ALV06209.1 | Pfam:pfam00006 ATP synthase alpha/beta family, nucleotide-binding domain. (474 aa) |
| | ALV06235.1 | Flagellar GTP-binding protein; Pfam:pfam00448 SRP54-type protein, GTPase domain. (566 aa) |
| | ALV06279.1 | Cell division inhibitor MinD; Pfam:pfam01656 CobQ/CobB/MinD/ParA nucleotide binding domain. (270 aa) |
| | dut | Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. (149 aa) |
| | ALV04699.1 | Pfam:pfam07728 AAA domain (dynein-related subfamily). (359 aa) |
| | ALV06444.1 | ATPase AAA; Pfam:pfam07726 ATPase family associated with various cellular activities (AAA). (318 aa) |
| | ALV06464.1 | Recombination factor protein RarA; Pfam:pfam12002 MgsA AAA+ ATPase C terminal. (456 aa) |
| | uvrB | Excinuclease ABC subunit B; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...] (727 aa) |
| | hscA | Molecular chaperone HscA; Chaperone involved in the maturation of iron-sulfur cluster- containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB. (618 aa) |
| | clpB | ATP-dependent Clp protease ATP-binding subunit ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. (864 aa) |
| | uppP | UDP pyrophosphate phosphatase; Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family. (288 aa) |
| | ftsH | Cell division protein FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. (634 aa) |
| | ALV06625.1 | Hypothetical protein. (137 aa) |
| | ALV06751.1 | LAO/AO transport system ATPase; Pfam:pfam03308 ArgK protein. (359 aa) |
| | smc | Chromosome partition protein Smc; Required for chromosome condensation and partitioning. Belongs to the SMC family. (1170 aa) |
| | ALV06808.1 | ATPase PulE/Tfp pilus assembly pathway; Pfam:pfam00437 Type II/IV secretion system protein. (609 aa) |
| | ALV06820.1 | Type II traffic warden ATPase; Pfam:pfam00437 Type II/IV secretion system protein. (862 aa) |
| | ALV06924.1 | Excinuclease ABC subunit A. (824 aa) |
| | ALV07062.1 | Hypothetical protein. (611 aa) |
| | ALV07063.1 | AAA ATPase, central domain protein; Pfam:pfam00004 ATPase family associated with various cellular activities (AAA). (523 aa) |
| | ALV07123.1 | Pfam:pfam07724 AAA domain (Cdc48 subfamily); Belongs to the ClpA/ClpB family. (883 aa) |
| | ALV07166.1 | ATPase; Pfam:pfam00122 E1-E2 ATPase. (871 aa) |
| | kdpB | Potassium-transporting ATPase subunit B; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system. Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily. (745 aa) |
| | ALV07256.1 | NADH pyrophosphatase; Pfam:pfam00293 NUDIX domain. (175 aa) |
| | ALV07370.1 | GTP-binding protein TypA; Pfam:pfam00009 Elongation factor Tu GTP binding domain. (607 aa) |
| | infB | Translation initiation factor IF-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily. (995 aa) |
| | ALV07455.1 | Hydrolase, NUDIX family; Pfam:pfam00293 NUDIX domain. (210 aa) |
| | ALV07551.1 | Hypothetical protein; Pfam:pfam13514 AAA domain. (1868 aa) |
| | ALV07565.1 | Type III secretion apparatus H+-transporting two-sector ATPase; Pfam:pfam00006 ATP synthase alpha/beta family, nucleotide-binding domain. (449 aa) |
| | ALV07594.1 | ATP-dependent DNA helicase; Pfam:pfam00580 UvrD/REP helicase N-terminal domain. (698 aa) |
| | fusA | Elongation factor G; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily. (700 aa) |
| | mutL | DNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. (685 aa) |
| | ALV07663.1 | Pfam:pfam00005 ABC transporter. (554 aa) |
| | ALV04827.1 | Hypothetical protein; Pfam:pfam05099 Tellurite resistance protein TerB. (168 aa) |
| | lpxH | UDP-2,3-diacylglucosamine hydrolase; Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. (271 aa) |
| | ALV07727.1 | ATP-dependent Clp protease ATP-binding protein; Pfam:pfam07724 AAA domain (Cdc48 subfamily); Belongs to the ClpA/ClpB family. (772 aa) |
| | ALV07764.1 | Putative cation transport P-type ATPase; Pfam:pfam00122 E1-E2 ATPase. (792 aa) |
| | guaA | GMP synthase; Catalyzes the synthesis of GMP from XMP. (534 aa) |
| | mfd | Transcription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. (1171 aa) |
| | ALV07886.1 | Phenylacetate-CoA oxygenase, PaaJ subunit; Pfam:pfam01883 Domain of unknown function DUF59. (182 aa) |
| | ALV07908.1 | Pfam:pfam00009 Elongation factor Tu GTP binding domain. (679 aa) |
| | ALV07915.1 | ATP-binding protein; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family. (364 aa) |
| | ALV07922.1 | Maf-like protein; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. (200 aa) |
| | ALV07985.1 | Pfam:pfam00006 ATP synthase alpha/beta family, nucleotide-binding domain. (446 aa) |
| | ALV08003.1 | Pfam:pfam13304 AAA domain. (246 aa) |
| | ALV08004.1 | RecF/RecN/SMC N-terminal domain-containing protein; Pfam:pfam13555 P-loop containing region of AAA domain. (939 aa) |
| | rsgA | GTPase RsgA; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit; Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily. (300 aa) |
| | ALV04864.1 | ATPase; Pfam:pfam00004 ATPase family associated with various cellular activities (AAA). (769 aa) |
| | ALV08074.1 | DNA mismatch repair protein MutT; Pfam:pfam00293 NUDIX domain. (242 aa) |
| | ALV08162.1 | Hypothetical protein; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. (201 aa) |
| | ureG | Urease accessory protein UreG; Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG. (216 aa) |
| | ALV05773.1 | Pfam:pfam00293 NUDIX domain; Belongs to the Nudix hydrolase family. (178 aa) |
| | ALV08239.1 | ATPase; Pfam:pfam00004 ATPase family associated with various cellular activities (AAA). (280 aa) |
| | ALV08272.1 | Pfam:pfam00293 NUDIX domain. (166 aa) |
| | ALV08292.1 | Type III secretion ATP synthase protein; Pfam:pfam00006 ATP synthase alpha/beta family, nucleotide-binding domain. (451 aa) |
| | ALV04890.1 | Gas vesicle protein GvpN; Pfam:pfam07728 AAA domain (dynein-related subfamily). (363 aa) |
| | ALV08363.1 | Sulfate adenylyltransferase; Pfam:pfam00009 Elongation factor Tu GTP binding domain. (432 aa) |
| | ALV08391.1 | Mazg nucleotide pyrophosphohydrolase. (396 aa) |
| | era | GTPase Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. (389 aa) |
| | lepA | Elongation factor 4; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. (602 aa) |
| | ALV08478.1 | Septum formation inhibitor Maf; Nucleoside triphosphate pyrophosphatase that hydrolyzes 7- methyl-GTP (m(7)GTP). May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids; Belongs to the Maf family. YceF subfamily. (233 aa) |
| | ftsZ | Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. (412 aa) |
| | ALV05638.1 | Hypothetical protein. (414 aa) |
| | rppH | RNA pyrophosphohydrolase; Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage; Belongs to the Nudix hydrolase family. RppH subfamily. (216 aa) |
| | obg | GTPase CgtA; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. (450 aa) |
| | ychF | GTP-binding protein; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner. (377 aa) |
| | ffh | Signal recognition particle protein Srp54; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual co [...] (467 aa) |
| | ftsY | Cell division protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components. (294 aa) |
| | ALV08660.1 | ATPase AAA; Pfam:pfam07726 ATPase family associated with various cellular activities (AAA). (326 aa) |
| | ALV08670.1 | RNA helicase; Pfam:pfam00270 DEAD/DEAH box helicase; Belongs to the DEAD box helicase family. (446 aa) |
| | fusA-2 | Elongation factor G; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily. (681 aa) |
| | ALV08724.1 | Excinuclease ABC, A subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. (1888 aa) |
| | ALV08772.1 | ATPase. (526 aa) |
| | ALV08797.1 | Metal ABC transporter ATPase; Pfam:pfam00122 E1-E2 ATPase. (823 aa) |
| | hslU | ATP-dependent protease ATP-binding subunit HslU; ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis. (444 aa) |
| | icmF | methylmalonyl-CoA mutase; Catalyzes the reversible interconversion of isobutyryl-CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly. (1097 aa) |
| | ALV08864.1 | Pfam:pfam03764 Elongation factor G, domain IV. (697 aa) |
| | ALV05495.1 | Type II traffic warden ATPase; Pfam:pfam00437 Type II/IV secretion system protein. (574 aa) |
| | ruvA | ATP-dependent DNA helicase RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. (189 aa) |
| | ruvB | Holliday junction ATP-dependent DNA helicase RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. (353 aa) |
| | rep | ATP-dependent DNA helicase Rep; Rep helicase is a single-stranded DNA-dependent ATPase involved in DNA replication; it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction. (687 aa) |
| | ALV04967.1 | Adenylate cyclase; Pfam:pfam01928 CYTH domain. (548 aa) |
| | nudJ | Pfam:pfam00293 NUDIX domain; Belongs to the Nudix hydrolase family. NudJ subfamily. (163 aa) |
| | uvrA | UvrABC system protein A; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. (1006 aa) |
| | ALV09162.1 | Pfam:pfam00122 E1-E2 ATPase. (843 aa) |
| | mnmE | tRNA modification GTPase TrmE; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family. (484 aa) |
| | tuf | Elongation factor Tu; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. (396 aa) |
| | fusA-3 | Elongation factor G; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily. (700 aa) |
| | ALV05050.1 | Pfam:pfam00009 Elongation factor Tu GTP binding domain. (396 aa) |
| | htpG | Chaperone protein HtpG; Molecular chaperone. Has ATPase activity. (633 aa) |
| | RD2015_93 | MazG nucleotide pyrophosphohydrolase. (109 aa) |
| | ALV05439.1 | General secretion pathway protein E; Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins. (479 aa) |
| | hisE | Pfam:pfam01503 Phosphoribosyl-ATP pyrophosphohydrolase. (131 aa) |
