(9 nodes) Synthesis and degradation of ketone bodies network (Roseateles depolymerans)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ALV05837.1	Acetyl-CoA acetyltransferase; Pfam:pfam00108 Thiolase, N-terminal domain; Belongs to the thiolase-like superfamily. Thiolase family. (395 aa)
	ALV05883.1	acetyl-CoA acetyltransferase; Pfam:pfam00108 Thiolase, N-terminal domain; Belongs to the thiolase-like superfamily. Thiolase family. (391 aa)
	ALV06416.1	Pfam:pfam01144 Coenzyme A transferase. (233 aa)
	ALV06417.1	Putative succinyl-CoA:3-ketoacid-coenzyme A transferase subunit B; Pfam:pfam01144 Coenzyme A transferase. (212 aa)
	ALV07335.1	Pfam:pfam00106 short chain dehydrogenase; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (260 aa)
	ALV07336.1	Pfam:pfam06314 Acetoacetate decarboxylase (ADC). (249 aa)
	ALV07847.1	Pfam:pfam00106 short chain dehydrogenase. (260 aa)
	ALV08781.1	Hydroxymethylglutaryl-CoA lyase YngG; Pfam:pfam00682 HMGL-like. (311 aa)
	ALV05325.1	acetyl-CoA acetyltransferase; Pfam:pfam00108 Thiolase, N-terminal domain; Belongs to the thiolase-like superfamily. Thiolase family. (392 aa)

Your Current Organism:

Roseateles depolymerans

NCBI taxonomy Id: 76731
Other names: CCUG 52219, DSM 11813, R. depolymerans, proteobacterium DSM11813, proteobacterium DSM11814, strain 61A

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ALV05325.1	ALV05837.1	RD2015_829	RD2015_1346	acetyl-CoA acetyltransferase; Pfam:pfam00108 Thiolase, N-terminal domain; Belongs to the thiolase-like superfamily. Thiolase family.	Acetyl-CoA acetyltransferase; Pfam:pfam00108 Thiolase, N-terminal domain; Belongs to the thiolase-like superfamily. Thiolase family.	0.908
ALV05325.1	ALV05883.1	RD2015_829	RD2015_1393	acetyl-CoA acetyltransferase; Pfam:pfam00108 Thiolase, N-terminal domain; Belongs to the thiolase-like superfamily. Thiolase family.	acetyl-CoA acetyltransferase; Pfam:pfam00108 Thiolase, N-terminal domain; Belongs to the thiolase-like superfamily. Thiolase family.	0.921
ALV05325.1	ALV06416.1	RD2015_829	RD2015_1938	acetyl-CoA acetyltransferase; Pfam:pfam00108 Thiolase, N-terminal domain; Belongs to the thiolase-like superfamily. Thiolase family.	Pfam:pfam01144 Coenzyme A transferase.	0.934
ALV05325.1	ALV06417.1	RD2015_829	RD2015_1939	acetyl-CoA acetyltransferase; Pfam:pfam00108 Thiolase, N-terminal domain; Belongs to the thiolase-like superfamily. Thiolase family.	Putative succinyl-CoA:3-ketoacid-coenzyme A transferase subunit B; Pfam:pfam01144 Coenzyme A transferase.	0.937
ALV05325.1	ALV08781.1	RD2015_829	RD2015_4338	acetyl-CoA acetyltransferase; Pfam:pfam00108 Thiolase, N-terminal domain; Belongs to the thiolase-like superfamily. Thiolase family.	Hydroxymethylglutaryl-CoA lyase YngG; Pfam:pfam00682 HMGL-like.	0.932
ALV05837.1	ALV05325.1	RD2015_1346	RD2015_829	Acetyl-CoA acetyltransferase; Pfam:pfam00108 Thiolase, N-terminal domain; Belongs to the thiolase-like superfamily. Thiolase family.	acetyl-CoA acetyltransferase; Pfam:pfam00108 Thiolase, N-terminal domain; Belongs to the thiolase-like superfamily. Thiolase family.	0.908
ALV05837.1	ALV05883.1	RD2015_1346	RD2015_1393	Acetyl-CoA acetyltransferase; Pfam:pfam00108 Thiolase, N-terminal domain; Belongs to the thiolase-like superfamily. Thiolase family.	acetyl-CoA acetyltransferase; Pfam:pfam00108 Thiolase, N-terminal domain; Belongs to the thiolase-like superfamily. Thiolase family.	0.912
ALV05837.1	ALV06416.1	RD2015_1346	RD2015_1938	Acetyl-CoA acetyltransferase; Pfam:pfam00108 Thiolase, N-terminal domain; Belongs to the thiolase-like superfamily. Thiolase family.	Pfam:pfam01144 Coenzyme A transferase.	0.934
ALV05837.1	ALV06417.1	RD2015_1346	RD2015_1939	Acetyl-CoA acetyltransferase; Pfam:pfam00108 Thiolase, N-terminal domain; Belongs to the thiolase-like superfamily. Thiolase family.	Putative succinyl-CoA:3-ketoacid-coenzyme A transferase subunit B; Pfam:pfam01144 Coenzyme A transferase.	0.937
ALV05837.1	ALV08781.1	RD2015_1346	RD2015_4338	Acetyl-CoA acetyltransferase; Pfam:pfam00108 Thiolase, N-terminal domain; Belongs to the thiolase-like superfamily. Thiolase family.	Hydroxymethylglutaryl-CoA lyase YngG; Pfam:pfam00682 HMGL-like.	0.932
ALV05883.1	ALV05325.1	RD2015_1393	RD2015_829	acetyl-CoA acetyltransferase; Pfam:pfam00108 Thiolase, N-terminal domain; Belongs to the thiolase-like superfamily. Thiolase family.	acetyl-CoA acetyltransferase; Pfam:pfam00108 Thiolase, N-terminal domain; Belongs to the thiolase-like superfamily. Thiolase family.	0.921
ALV05883.1	ALV05837.1	RD2015_1393	RD2015_1346	acetyl-CoA acetyltransferase; Pfam:pfam00108 Thiolase, N-terminal domain; Belongs to the thiolase-like superfamily. Thiolase family.	Acetyl-CoA acetyltransferase; Pfam:pfam00108 Thiolase, N-terminal domain; Belongs to the thiolase-like superfamily. Thiolase family.	0.912
ALV05883.1	ALV06416.1	RD2015_1393	RD2015_1938	acetyl-CoA acetyltransferase; Pfam:pfam00108 Thiolase, N-terminal domain; Belongs to the thiolase-like superfamily. Thiolase family.	Pfam:pfam01144 Coenzyme A transferase.	0.934
ALV05883.1	ALV06417.1	RD2015_1393	RD2015_1939	acetyl-CoA acetyltransferase; Pfam:pfam00108 Thiolase, N-terminal domain; Belongs to the thiolase-like superfamily. Thiolase family.	Putative succinyl-CoA:3-ketoacid-coenzyme A transferase subunit B; Pfam:pfam01144 Coenzyme A transferase.	0.937
ALV05883.1	ALV08781.1	RD2015_1393	RD2015_4338	acetyl-CoA acetyltransferase; Pfam:pfam00108 Thiolase, N-terminal domain; Belongs to the thiolase-like superfamily. Thiolase family.	Hydroxymethylglutaryl-CoA lyase YngG; Pfam:pfam00682 HMGL-like.	0.932
ALV06416.1	ALV05325.1	RD2015_1938	RD2015_829	Pfam:pfam01144 Coenzyme A transferase.	acetyl-CoA acetyltransferase; Pfam:pfam00108 Thiolase, N-terminal domain; Belongs to the thiolase-like superfamily. Thiolase family.	0.934
ALV06416.1	ALV05837.1	RD2015_1938	RD2015_1346	Pfam:pfam01144 Coenzyme A transferase.	Acetyl-CoA acetyltransferase; Pfam:pfam00108 Thiolase, N-terminal domain; Belongs to the thiolase-like superfamily. Thiolase family.	0.934
ALV06416.1	ALV05883.1	RD2015_1938	RD2015_1393	Pfam:pfam01144 Coenzyme A transferase.	acetyl-CoA acetyltransferase; Pfam:pfam00108 Thiolase, N-terminal domain; Belongs to the thiolase-like superfamily. Thiolase family.	0.934
ALV06416.1	ALV06417.1	RD2015_1938	RD2015_1939	Pfam:pfam01144 Coenzyme A transferase.	Putative succinyl-CoA:3-ketoacid-coenzyme A transferase subunit B; Pfam:pfam01144 Coenzyme A transferase.	0.999
ALV06416.1	ALV07335.1	RD2015_1938	RD2015_2871	Pfam:pfam01144 Coenzyme A transferase.	Pfam:pfam00106 short chain dehydrogenase; Belongs to the short-chain dehydrogenases/reductases (SDR) family.	0.903