22 items (Aspergillus brasiliensis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

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Your Input:
	A0A1L9U1P2	AAA domain-containing protein. (315 aa)
	A0A1L9U2T4	Uncharacterized protein. (755 aa)
	A0A1L9U3Z6	EthD domain-containing protein. (171 aa)
	A0A1L9U609	Pectinesterase; Involved in maceration and soft-rotting of plant tissue. (327 aa)
	A0A1L9UBX3	Checkpoint protein; Belongs to the HUS1 family. (393 aa)
	A0A1L9UC00	AAA domain-containing protein. (352 aa)
	A0A1L9UCI3	BRCT domain-containing protein. (1349 aa)
	A0A1L9UI62	Uncharacterized protein. (598 aa)
	A0A1L9UK56	Uncharacterized protein. (759 aa)
	A0A1L9UKR8	AAA domain-containing protein. (400 aa)
	A0A1L9UP58	RPA_C domain-containing protein. (291 aa)
	A0A1L9UP68	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. (797 aa)
	A0A1L9USK0	Uncharacterized protein. (473 aa)
	A0A1L9UT08	Uncharacterized protein. (575 aa)
	A0A1L9UUV4	Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism. (606 aa)
	A0A1L9UVP5	AAA domain-containing protein. (758 aa)
	A0A1L9UXB3	AAA domain-containing protein. (582 aa)
	A0A1L9UXT0	DNA repair protein rad9; Acts in DNA repair and mutagenesis. Involved in promoting resistance to ionizing radiation and UV light, as well as regulating cell cycle progression after irradiation. (456 aa)
	A0A1L9UYL3	Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (2462 aa)
	A0A1L9UZW3	Uncharacterized protein. (784 aa)
	A0A1L9V0A9	Serine/threonine-protein kinase Tel1; Serine/threonine protein kinase which activates checkpoint signaling upon genotoxic stresses such as ionizing radiation (IR), ultraviolet light (UV), or DNA replication stalling, thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates histone H2A to form H2AS128ph (gamma-H2A) at sites of DNA damage, involved in the regulation of DNA damage response mechanism. Required for the control of telomere length and genome stability; Belongs to the PI3/PI4-kinase family. ATM subfamily. (2901 aa)
	FEN1	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] (359 aa)

Your Current Organism:

Aspergillus brasiliensis

NCBI taxonomy Id: 767769
Other names: A. brasiliensis CBS 101740, Aspergillus brasiliensis CBS 101740

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A1L9U1P2	A0A1L9U2T4	A0A1L9U1P2	A0A1L9U2T4	AAA domain-containing protein.	Uncharacterized protein.	0.980
A0A1L9U1P2	A0A1L9U3Z6	A0A1L9U1P2	A0A1L9U3Z6	AAA domain-containing protein.	EthD domain-containing protein.	0.804
A0A1L9U1P2	A0A1L9U609	A0A1L9U1P2	A0A1L9U609	AAA domain-containing protein.	Pectinesterase; Involved in maceration and soft-rotting of plant tissue.	0.805
A0A1L9U1P2	A0A1L9UBX3	A0A1L9U1P2	A0A1L9UBX3	AAA domain-containing protein.	Checkpoint protein; Belongs to the HUS1 family.	0.961
A0A1L9U1P2	A0A1L9UC00	A0A1L9U1P2	A0A1L9UC00	AAA domain-containing protein.	AAA domain-containing protein.	0.993
A0A1L9U1P2	A0A1L9UCI3	A0A1L9U1P2	A0A1L9UCI3	AAA domain-containing protein.	BRCT domain-containing protein.	0.538
A0A1L9U1P2	A0A1L9UI62	A0A1L9U1P2	A0A1L9UI62	AAA domain-containing protein.	Uncharacterized protein.	0.777
A0A1L9U1P2	A0A1L9UK56	A0A1L9U1P2	A0A1L9UK56	AAA domain-containing protein.	Uncharacterized protein.	0.828
A0A1L9U1P2	A0A1L9UKR8	A0A1L9U1P2	A0A1L9UKR8	AAA domain-containing protein.	AAA domain-containing protein.	0.867
A0A1L9U1P2	A0A1L9UP58	A0A1L9U1P2	A0A1L9UP58	AAA domain-containing protein.	RPA_C domain-containing protein.	0.848
A0A1L9U1P2	A0A1L9UP68	A0A1L9U1P2	A0A1L9UP68	AAA domain-containing protein.	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.	0.817
A0A1L9U1P2	A0A1L9USK0	A0A1L9U1P2	A0A1L9USK0	AAA domain-containing protein.	Uncharacterized protein.	0.952
A0A1L9U1P2	A0A1L9UT08	A0A1L9U1P2	A0A1L9UT08	AAA domain-containing protein.	Uncharacterized protein.	0.720
A0A1L9U1P2	A0A1L9UUV4	A0A1L9U1P2	A0A1L9UUV4	AAA domain-containing protein.	Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism.	0.854
A0A1L9U1P2	A0A1L9UVP5	A0A1L9U1P2	A0A1L9UVP5	AAA domain-containing protein.	AAA domain-containing protein.	0.996
A0A1L9U1P2	A0A1L9UXB3	A0A1L9U1P2	A0A1L9UXB3	AAA domain-containing protein.	AAA domain-containing protein.	0.992
A0A1L9U1P2	A0A1L9UXT0	A0A1L9U1P2	A0A1L9UXT0	AAA domain-containing protein.	DNA repair protein rad9; Acts in DNA repair and mutagenesis. Involved in promoting resistance to ionizing radiation and UV light, as well as regulating cell cycle progression after irradiation.	0.951
A0A1L9U1P2	A0A1L9UYL3	A0A1L9U1P2	A0A1L9UYL3	AAA domain-containing protein.	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	0.846
A0A1L9U1P2	A0A1L9UZW3	A0A1L9U1P2	A0A1L9UZW3	AAA domain-containing protein.	Uncharacterized protein.	0.821
A0A1L9U1P2	A0A1L9V0A9	A0A1L9U1P2	A0A1L9V0A9	AAA domain-containing protein.	Serine/threonine-protein kinase Tel1; Serine/threonine protein kinase which activates checkpoint signaling upon genotoxic stresses such as ionizing radiation (IR), ultraviolet light (UV), or DNA replication stalling, thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates histone H2A to form H2AS128ph (gamma-H2A) at sites of DNA damage, involved in the regulation of DNA damage response mechanism. Required for the control of telomere length and genome stability; Belongs to the PI3/PI4-kinase family. ATM subfamily.	0.837