62 items (Aspergillus brasiliensis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

Your Input:
	A0A1L9U9W4	Uncharacterized protein. (484 aa)
	A0A1L9UC83	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (324 aa)
	A0A1L9UCT6	DNA helicase; Belongs to the MCM family. (898 aa)
	A0A1L9UFR6	Uncharacterized protein. (769 aa)
	A0A1L9UFZ1	Uncharacterized protein. (150 aa)
	A0A1L9UH89	Sld5 domain-containing protein. (178 aa)
	A0A1L9UHC6	Cnn_1N domain-containing protein. (996 aa)
	A0A1L9UI39	Uncharacterized protein. (536 aa)
	A0A1L9UIE4	BZIP domain-containing protein. (254 aa)
	MCM7	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (807 aa)
	A0A1L9UK55	DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2234 aa)
	A0A1L9UKA9	DNA primase; Belongs to the eukaryotic-type primase small subunit family. (514 aa)
	A0A1L9UKR8	AAA domain-containing protein. (400 aa)
	A0A1L9UMP2	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (418 aa)
	A0A1L9UQ66	CBFD_NFYB_HMF domain-containing protein. (303 aa)
	A0A1L9UQ83	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (450 aa)
	A0A1L9UQD3	Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. (804 aa)
	A0A1L9USL7	Sld5 domain-containing protein. (234 aa)
	A0A1L9USW6	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (480 aa)
	A0A1L9UT08	Uncharacterized protein. (575 aa)
	A0A1L9UT64	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (294 aa)
	A0A1L9UTI5	Vezatin domain-containing protein. (615 aa)
	A0A1L9UTJ2	DNA primase large subunit; DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication; Belongs to the eukaryotic-type primase large subunit family. (500 aa)
	A0A1L9UTT6	MCM domain-containing protein; Belongs to the MCM family. (2087 aa)
	A0A1L9UTZ1	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (258 aa)
	A0A1L9UUK5	DNA_pol_E_B domain-containing protein. (748 aa)
	A0A1L9UUV4	Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism. (606 aa)
	A0A1L9UVP5	AAA domain-containing protein. (758 aa)
	A0A1L9UW37	DNA_LIGASE_A3 domain-containing protein. (1022 aa)
	A0A1L9UW45	DNA helicase; Belongs to the MCM family. (720 aa)
	A0A1L9UWC2	Uncharacterized protein. (532 aa)
	A0A1L9UWN8	DNA ligase. (839 aa)
	A0A1L9UX45	Ubiquitin-like domain-containing protein. (154 aa)
	A0A1L9UX78	Replication factor C subunit 1. (1059 aa)
	A0A1L9UXB3	AAA domain-containing protein. (582 aa)
	A0A1L9UXT1	DNA replication complex GINS protein PSF2; Belongs to the GINS2/PSF2 family. (269 aa)
	A0A1L9UXY3	DNA polymerase. (1929 aa)
	A0A1L9UZM8	DNA helicase; Belongs to the MCM family. (962 aa)
	A0A1L9UZY8	CBFD_NFYB_HMF domain-containing protein. (186 aa)
	A0A1L9V076	DNA polymerase alpha subunit B; Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis. (650 aa)
	A0A1L9V0B1	Uncharacterized protein. (122 aa)
	A0A1L9V0Z0	Uncharacterized protein. (197 aa)
	A0A1L9V146	Uncharacterized protein. (468 aa)
	A0A1L9V167	Zds_C domain-containing protein. (870 aa)
	A0A1L9V173	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (294 aa)
	A0A1L9V1B6	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (323 aa)
	A0A1L9V1C5	DNA replication complex GINS protein SLD5; The GINS complex plays an essential role in the initiation of DNA replication; Belongs to the GINS4/SLD5 family. (275 aa)
	FEN1	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] (359 aa)
	A0A1L9UAS1	RING-type domain-containing protein. (120 aa)
	A0A1L9UC00	AAA domain-containing protein. (352 aa)
	A0A1L9U8S5	Uncharacterized protein. (177 aa)
	A0A1L9U832	ATPase_AAA_core domain-containing protein. (270 aa)
	A0A1L9U7W2	Uncharacterized protein. (414 aa)
	A0A1L9U6N5	DNA helicase; Belongs to the MCM family. (1027 aa)
	A0A1L9U6N2	DNA ligase. (884 aa)
	A0A1L9U6G6	Uncharacterized protein. (286 aa)
	A0A1L9U6A6	Uncharacterized protein. (450 aa)
	A0A1L9U5R5	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (633 aa)
	A0A1L9U5R1	DNA polymerase. (1105 aa)
	A0A1L9U4W4	Cell division control protein; Belongs to the CDC6/cdc18 family. (635 aa)
	A0A1L9U3I2	Uncharacterized protein. (370 aa)
	A0A1L9U1P2	AAA domain-containing protein. (315 aa)

Your Current Organism:

Aspergillus brasiliensis

NCBI taxonomy Id: 767769
Other names: A. brasiliensis CBS 101740, Aspergillus brasiliensis CBS 101740

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A1L9U1P2	A0A1L9U4W4	A0A1L9U1P2	A0A1L9U4W4	AAA domain-containing protein.	Cell division control protein; Belongs to the CDC6/cdc18 family.	0.533
A0A1L9U1P2	A0A1L9U5R1	A0A1L9U1P2	A0A1L9U5R1	AAA domain-containing protein.	DNA polymerase.	0.834
A0A1L9U1P2	A0A1L9U6A6	A0A1L9U1P2	A0A1L9U6A6	AAA domain-containing protein.	Uncharacterized protein.	0.564
A0A1L9U1P2	A0A1L9U6N2	A0A1L9U1P2	A0A1L9U6N2	AAA domain-containing protein.	DNA ligase.	0.842
A0A1L9U1P2	A0A1L9U6N5	A0A1L9U1P2	A0A1L9U6N5	AAA domain-containing protein.	DNA helicase; Belongs to the MCM family.	0.709
A0A1L9U1P2	A0A1L9UAS1	A0A1L9U1P2	A0A1L9UAS1	AAA domain-containing protein.	RING-type domain-containing protein.	0.683
A0A1L9U1P2	A0A1L9UC00	A0A1L9U1P2	A0A1L9UC00	AAA domain-containing protein.	AAA domain-containing protein.	0.993
A0A1L9U1P2	A0A1L9UCT6	A0A1L9U1P2	A0A1L9UCT6	AAA domain-containing protein.	DNA helicase; Belongs to the MCM family.	0.839
A0A1L9U1P2	A0A1L9UI39	A0A1L9U1P2	A0A1L9UI39	AAA domain-containing protein.	Uncharacterized protein.	0.812
A0A1L9U1P2	A0A1L9UIE4	A0A1L9U1P2	A0A1L9UIE4	AAA domain-containing protein.	BZIP domain-containing protein.	0.680
A0A1L9U1P2	A0A1L9UK55	A0A1L9U1P2	A0A1L9UK55	AAA domain-containing protein.	DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family.	0.829
A0A1L9U1P2	A0A1L9UKA9	A0A1L9U1P2	A0A1L9UKA9	AAA domain-containing protein.	DNA primase; Belongs to the eukaryotic-type primase small subunit family.	0.870
A0A1L9U1P2	A0A1L9UKR8	A0A1L9U1P2	A0A1L9UKR8	AAA domain-containing protein.	AAA domain-containing protein.	0.867
A0A1L9U1P2	A0A1L9UQ66	A0A1L9U1P2	A0A1L9UQ66	AAA domain-containing protein.	CBFD_NFYB_HMF domain-containing protein.	0.726
A0A1L9U1P2	A0A1L9UQD3	A0A1L9U1P2	A0A1L9UQD3	AAA domain-containing protein.	Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication.	0.552
A0A1L9U1P2	A0A1L9USL7	A0A1L9U1P2	A0A1L9USL7	AAA domain-containing protein.	Sld5 domain-containing protein.	0.439
A0A1L9U1P2	A0A1L9UT08	A0A1L9U1P2	A0A1L9UT08	AAA domain-containing protein.	Uncharacterized protein.	0.720
A0A1L9U1P2	A0A1L9UTI5	A0A1L9U1P2	A0A1L9UTI5	AAA domain-containing protein.	Vezatin domain-containing protein.	0.962
A0A1L9U1P2	A0A1L9UTJ2	A0A1L9U1P2	A0A1L9UTJ2	AAA domain-containing protein.	DNA primase large subunit; DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication; Belongs to the eukaryotic-type primase large subunit family.	0.869
A0A1L9U1P2	A0A1L9UTT6	A0A1L9U1P2	A0A1L9UTT6	AAA domain-containing protein.	MCM domain-containing protein; Belongs to the MCM family.	0.708