46 items (Aspergillus brasiliensis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	A0A1L9UM34	DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (629 aa)
	A0A1L9UA83	Uncharacterized protein. (148 aa)
	A0A1L9UAG6	Uncharacterized protein. (1772 aa)
	A0A1L9UCH9	HD domain-containing protein. (236 aa)
	A0A1L9UCX9	BTP domain-containing protein. (910 aa)
	A0A1L9UFR6	Uncharacterized protein. (769 aa)
	A0A1L9UFU1	Uncharacterized protein. (390 aa)
	A0A1L9UFZ1	Uncharacterized protein. (150 aa)
	A0A1L9UP68	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. (797 aa)
	A0A1L9UPP0	Uncharacterized protein. (148 aa)
	A0A1L9UPS1	Smr domain-containing protein. (267 aa)
	A0A1L9UQ99	Uncharacterized protein. (87 aa)
	A0A1L9UR06	PITH domain-containing protein. (222 aa)
	A0A1L9URM3	Uncharacterized protein. (989 aa)
	A0A1L9URW2	Uncharacterized protein. (727 aa)
	A0A1L9UUV4	Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism. (606 aa)
	A0A1L9UVZ4	Uncharacterized protein. (290 aa)
	A0A1L9UI39	Uncharacterized protein. (536 aa)
	A0A1L9UI62	Uncharacterized protein. (598 aa)
	A0A1L9UID3	ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. (541 aa)
	A0A1L9UP58	RPA_C domain-containing protein. (291 aa)
	A0A1L9UNL5	Uncharacterized protein. (1563 aa)
	A0A1L9UM47	Uncharacterized protein. (277 aa)
	A0A1L9V0A9	Serine/threonine-protein kinase Tel1; Serine/threonine protein kinase which activates checkpoint signaling upon genotoxic stresses such as ionizing radiation (IR), ultraviolet light (UV), or DNA replication stalling, thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates histone H2A to form H2AS128ph (gamma-H2A) at sites of DNA damage, involved in the regulation of DNA damage response mechanism. Required for the control of telomere length and genome stability; Belongs to the PI3/PI4-kinase family. ATM subfamily. (2901 aa)
	A0A1L9UZW3	Uncharacterized protein. (784 aa)
	A0A1L9UY38	Uncharacterized protein. (614 aa)
	A0A1L9UY29	Stn1 domain-containing protein. (227 aa)
	A0A1L9UW92	Uncharacterized protein. (180 aa)
	A0A1L9UWG6	ERCC4 domain-containing protein. (580 aa)
	A0A1L9UWC2	Uncharacterized protein. (532 aa)
	A0A1L9U3Z6	EthD domain-containing protein. (171 aa)
	A0A1L9U3I2	Uncharacterized protein. (370 aa)
	A0A1L9U5R1	DNA polymerase. (1105 aa)
	A0A1L9U6A6	Uncharacterized protein. (450 aa)
	A0A1L9U6G6	Uncharacterized protein. (286 aa)
	A0A1L9U7W2	Uncharacterized protein. (414 aa)
	A0A1L9U836	FHA domain-containing protein. (692 aa)
	A0A1L9U8S5	Uncharacterized protein. (177 aa)
	A0A1L9U9W4	Uncharacterized protein. (484 aa)
	A0A1L9V0B1	Uncharacterized protein. (122 aa)
	A0A1L9V0S2	Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (214 aa)
	A0A1L9V0Z0	Uncharacterized protein. (197 aa)
	A0A1L9V167	Zds_C domain-containing protein. (870 aa)
	A0A1L9V1Q2	Uncharacterized protein. (1548 aa)
	A0A1L9V2F8	Fido domain-containing protein. (137 aa)
	A0A1L9UKW9	RECA_2 domain-containing protein. (481 aa)

Your Current Organism:

Aspergillus brasiliensis

NCBI taxonomy Id: 767769
Other names: A. brasiliensis CBS 101740, Aspergillus brasiliensis CBS 101740

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Browse interactions in tabular form:

node1	node2	node1 annotation	node2 annotation	score
A0A1L9U3I2	A0A1L9UP58	Uncharacterized protein.	RPA_C domain-containing protein.	0.781
A0A1L9U3I2	A0A1L9UUV4	Uncharacterized protein.	Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism.	0.792
A0A1L9U3I2	A0A1L9UWG6	Uncharacterized protein.	ERCC4 domain-containing protein.	0.553
A0A1L9U3I2	A0A1L9UY29	Uncharacterized protein.	Stn1 domain-containing protein.	0.641
A0A1L9U3Z6	A0A1L9U5R1	EthD domain-containing protein.	DNA polymerase.	0.796
A0A1L9U3Z6	A0A1L9U6A6	EthD domain-containing protein.	Uncharacterized protein.	0.703
A0A1L9U3Z6	A0A1L9UA83	EthD domain-containing protein.	Uncharacterized protein.	0.558
A0A1L9U3Z6	A0A1L9UAG6	EthD domain-containing protein.	Uncharacterized protein.	0.474
A0A1L9U3Z6	A0A1L9UCH9	EthD domain-containing protein.	HD domain-containing protein.	0.570
A0A1L9U3Z6	A0A1L9UCX9	EthD domain-containing protein.	BTP domain-containing protein.	0.736
A0A1L9U3Z6	A0A1L9UFU1	EthD domain-containing protein.	Uncharacterized protein.	0.909
A0A1L9U3Z6	A0A1L9UI39	EthD domain-containing protein.	Uncharacterized protein.	0.655
A0A1L9U3Z6	A0A1L9UI62	EthD domain-containing protein.	Uncharacterized protein.	0.938
A0A1L9U3Z6	A0A1L9UKW9	EthD domain-containing protein.	RECA_2 domain-containing protein.	0.853
A0A1L9U3Z6	A0A1L9UM34	EthD domain-containing protein.	DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family.	0.955
A0A1L9U3Z6	A0A1L9UM47	EthD domain-containing protein.	Uncharacterized protein.	0.570
A0A1L9U3Z6	A0A1L9UNL5	EthD domain-containing protein.	Uncharacterized protein.	0.663
A0A1L9U3Z6	A0A1L9UP58	EthD domain-containing protein.	RPA_C domain-containing protein.	0.929
A0A1L9U3Z6	A0A1L9UP68	EthD domain-containing protein.	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.	0.952
A0A1L9U3Z6	A0A1L9UPP0	EthD domain-containing protein.	Uncharacterized protein.	0.938