STRINGSTRING
AGK99674.1 AGK99674.1 AGK99719.1 AGK99719.1 glmU glmU prs prs AGK99978.1 AGK99978.1 glmM glmM glmS glmS AGL00266.1 AGL00266.1 AGL00438.1 AGL00438.1 AGL00504.1 AGL00504.1 AGL00560.1 AGL00560.1 AGL00697.1 AGL00697.1 murI murI AGL01116.1 AGL01116.1 AGL01174.1 AGL01174.1 AGL01197.1 AGL01197.1 ddl ddl AGL01208.1 AGL01208.1 AGL01304.1 AGL01304.1 AGL01323.1 AGL01323.1 minC minC ddl-2 ddl-2 AGL01560.1 AGL01560.1 AGL01609.1 AGL01609.1 AGL01610.1 AGL01610.1 rph rph AGL01612.1 AGL01612.1 AGL01613.1 AGL01613.1 AGL01616.1 AGL01616.1 AGL01927.1 AGL01927.1 AGL01980.1 AGL01980.1 AGL02076.1 AGL02076.1 AGL02143.1 AGL02143.1 AGL02311.1 AGL02311.1 AGL02467.1 AGL02467.1 AGL02639.1 AGL02639.1 AGL02640.1 AGL02640.1 AGL02641.1 AGL02641.1 AGL02642.1 AGL02642.1 rodA rodA minE minE AGL02645.1 AGL02645.1 AGL02646.1 AGL02646.1 AGL02647.1 AGL02647.1 AGL02648.1 AGL02648.1 AGL02649.1 AGL02649.1 AGL02650.1 AGL02650.1 AGL02651.1 AGL02651.1 AGL02652.1 AGL02652.1 AGL02653.1 AGL02653.1 AGL02654.1 AGL02654.1 AGL02704.1 AGL02704.1 ftsZ ftsZ ftsA ftsA AGL02967.1 AGL02967.1 murA murA murB murB murC murC murG murG AGL02981.1 AGL02981.1 murD murD mraY mraY murF murF AGL02985.1 AGL02985.1 murE murE AGL02987.1 AGL02987.1 ftsL ftsL rsmH rsmH mraZ mraZ AGL02996.1 AGL02996.1 AGL03192.1 AGL03192.1 AGL03319.1 AGL03319.1 AGL03355.1 AGL03355.1 AGL03570.1 AGL03570.1 AGL03571.1 AGL03571.1 AGL03572.1 AGL03572.1 AGL03573.1 AGL03573.1 ftsE ftsE AGL03577.1 AGL03577.1 AGL03808.1 AGL03808.1 murA-2 murA-2 AGL03838.1 AGL03838.1 AGL03854.1 AGL03854.1 murA-3 murA-3 AGL03954.1 AGL03954.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AGK99674.1LysM repeat-containing protein; PFAM: LysM domain. (295 aa)
AGK99719.1Hypothetical protein. (333 aa)
glmUUDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. (459 aa)
prsRibose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (314 aa)
AGK99978.1PFAM: N-acetylmuramoyl-L-alanine amidase; TIGRFAM: N-acetylmuramoyl-L-alanine amidase CwlD. (268 aa)
glmMPhosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. (444 aa)
glmSGlucosamine--fructose-6-phosphate aminotransferase, isomerizing; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. (609 aa)
AGL00266.1PFAM: Peptidase S24-like; TIGRFAM: signal peptidase I, bacterial type; Belongs to the peptidase S26 family. (182 aa)
AGL00438.1PFAM: Putative peptidoglycan binding domain; Glycosyl hydrolases family 18. (442 aa)
AGL00504.1N-acetylmuramoyl-L-alanine amidase; PFAM: Copper amine oxidase N-terminal domain; N-acetylmuramoyl-L-alanine amidase; Localisation of periplasmic protein complexes. (476 aa)
AGL00560.1C-terminal processing peptidase; PFAM: Peptidase family S41; PDZ domain (Also known as DHR or GLGF); TIGRFAM: C-terminal peptidase (prc); Belongs to the peptidase S41A family. (388 aa)
AGL00697.1PFAM: Copper amine oxidase N-terminal domain; D-alanyl-D-alanine carboxypeptidase. (330 aa)
murIGlutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. (266 aa)
AGL01116.1PFAM: D-alanyl-D-alanine carboxypeptidase; Penicillin-binding protein 5, C-terminal domain; Belongs to the peptidase S11 family. (385 aa)
AGL01174.1Penicillin-binding protein, 1A family; PFAM: Penicillin binding protein transpeptidase domain; Transglycosylase; TIGRFAM: penicillin-binding protein, 1A family. (767 aa)
AGL01197.1PFAM: D-alanyl-D-alanine carboxypeptidase; Belongs to the peptidase S11 family. (341 aa)
ddlD-alanine--D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. (351 aa)
AGL01208.1Alanine racemase; PFAM: Acyltransferase family; Alanine racemase, N-terminal domain; TIGRFAM: alanine racemase. (571 aa)
AGL01304.1PFAM: D-alanyl-D-alanine carboxypeptidase; Penicillin-binding protein 5, C-terminal domain; Belongs to the peptidase S11 family. (383 aa)
AGL01323.1Hypothetical protein. (254 aa)
minCSeptum site-determining protein MinC; Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization; Belongs to the MinC family. (218 aa)
ddl-2D-alanine--D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. (311 aa)
AGL01560.1Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. (377 aa)
AGL01609.1Phosphoesterase, MJ0936 family; PFAM: Calcineurin-like phosphoesterase; TIGRFAM: phosphoesterase, MJ0936 family. (181 aa)
AGL01610.1Non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. (221 aa)
rphRibonuclease PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation. (249 aa)
AGL01612.1Metal-dependent hydrolase, beta-lactamase superfamily III; PFAM: Metallo-beta-lactamase superfamily. (263 aa)
AGL01613.1PFAM: N-acetylmuramoyl-L-alanine amidase; Localisation of periplasmic protein complexes; Bacterial SH3 domain. (792 aa)
AGL01616.1Hypothetical protein; PFAM: Putative peptidoglycan binding domain; L,D-transpeptidase catalytic domain. (328 aa)
AGL01927.1PFAM: LysM domain; Cell Wall Hydrolase. (270 aa)
AGL01980.1PFAM: D-alanyl-D-alanine carboxypeptidase; Penicillin-binding protein 5, C-terminal domain; Belongs to the peptidase S11 family. (418 aa)
AGL02076.1Cell division protein FtsI/penicillin-binding protein 2; PFAM: Penicillin binding protein transpeptidase domain; Penicillin-binding Protein dimerisation domain. (573 aa)
AGL02143.1PFAM: Peptidase S24-like; TIGRFAM: signal peptidase I, bacterial type; Belongs to the peptidase S26 family. (183 aa)
AGL02311.1PFAM: Alanine dehydrogenase/PNT, C-terminal domain; Alanine dehydrogenase/PNT, N-terminal domain; TIGRFAM: alanine dehydrogenase; Belongs to the AlaDH/PNT family. (370 aa)
AGL02467.1Hypothetical protein. (216 aa)
AGL02639.1Radical SAM-linked protein; PFAM: Uncharacterized protein conserved in bacteria (DUF2344); TIGRFAM: radical SAM-linked protein. (218 aa)
AGL02640.1PFAM: Radical SAM superfamily; TIGRFAM: radical SAM family uncharacterized protein. (626 aa)
AGL02641.1Zn-dependent protease; PFAM: Peptidase family M50. (291 aa)
AGL02642.1Membrane-bound metallopeptidase; PFAM: Peptidase family M23. (333 aa)
rodARod shape-determining protein RodA; Peptidoglycan polymerase that is essential for cell wall elongation; Belongs to the SEDS family. MrdB/RodA subfamily. (397 aa)
minECell division topological specificity factor MinE; Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell. (93 aa)
AGL02645.1PFAM: CobQ/CobB/MinD/ParA nucleotide binding domain; TIGRFAM: septum site-determining protein MinD. (264 aa)
AGL02646.1Septum site-determining protein MinC; Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization. (141 aa)
AGL02647.1Cell division protein FtsI/penicillin-binding protein 2; PFAM: Penicillin binding protein transpeptidase domain; Penicillin-binding Protein dimerisation domain. (938 aa)
AGL02648.1PFAM: rod shape-determining protein MreD; TIGRFAM: rod shape-determining protein MreD. (169 aa)
AGL02649.1Rod shape-determining protein MreC; Involved in formation and maintenance of cell shape. (280 aa)
AGL02650.1PFAM: MreB/Mbl protein; TIGRFAM: cell shape determining protein, MreB/Mrl family. (343 aa)
AGL02651.1DNA repair protein radc; PFAM: Protein of unknown function (DUF2466); TIGRFAM: DNA repair protein radc; Belongs to the UPF0758 family. (231 aa)
AGL02652.1MAF protein; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. (195 aa)
AGL02653.1Hypothetical protein. (85 aa)
AGL02654.1Hypothetical protein. (82 aa)
AGL02704.1Putative membrane protein; PFAM: Rhomboid family. (227 aa)
ftsZCell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. (353 aa)
ftsACell division protein FtsA; Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring. Belongs to the FtsA/MreB family. (402 aa)
AGL02967.1Cell division septal protein; Essential cell division protein. (246 aa)
murAUDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. (417 aa)
murBUDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation. (303 aa)
murCUDP-N-acetylmuramate--alanine ligase; Cell wall formation; Belongs to the MurCDEF family. (459 aa)
murGUndecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. (368 aa)
AGL02981.1PFAM: Cell cycle protein; TIGRFAM: rod shape-determining protein RodA; cell division protein FtsW; Belongs to the SEDS family. (371 aa)
murDUDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. (450 aa)
mraYphospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. (332 aa)
murFUDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. (462 aa)
AGL02985.1Hypothetical protein. (37 aa)
murEUDP-N-acetylmuramyl-tripeptide synthetase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. (498 aa)
AGL02987.1Stage V sporulation protein D; PFAM: Penicillin binding protein transpeptidase domain; Penicillin-binding Protein dimerisation domain; PASTA domain; TIGRFAM: stage V sporulation protein D. (733 aa)
ftsLSeptum formation initiator; Essential cell division protein; Belongs to the FtsL family. (177 aa)
rsmHS-adenosyl-methyltransferase MraW; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA. (328 aa)
mraZPFAM: MraZ protein; TIGRFAM: mraZ protein; Belongs to the MraZ family. (145 aa)
AGL02996.1PFAM: D-alanyl-D-alanine carboxypeptidase; Penicillin-binding protein 5, C-terminal domain; Belongs to the peptidase S11 family. (422 aa)
AGL03192.1PFAM: Alanine dehydrogenase/PNT, C-terminal domain; Alanine dehydrogenase/PNT, N-terminal domain; TIGRFAM: alanine dehydrogenase. (374 aa)
AGL03319.1PFAM: Stage II sporulation protein. (379 aa)
AGL03355.1Cell wall-associated hydrolase, invasion-associated protein; PFAM: NlpC/P60 family; LysM domain. (227 aa)
AGL03570.1Periplasmic protease; PFAM: PDZ domain (Also known as DHR or GLGF). (413 aa)
AGL03571.1C-terminal processing peptidase; PFAM: Peptidase family S41; PDZ domain (Also known as DHR or GLGF); TIGRFAM: C-terminal peptidase (prc); Belongs to the peptidase S41A family. (383 aa)
AGL03572.1Metalloendopeptidase-like membrane protein; PFAM: Peptidase family M23. (377 aa)
AGL03573.1Cell division protein; Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation. Belongs to the ABC-4 integral membrane protein family. FtsX subfamily. (295 aa)
ftsECell division ATP-binding protein FtsE; Part of the ABC transporter FtsEX involved in cellular division. (228 aa)
AGL03577.1Hypothetical protein; PFAM: Uncharacterized BCR, YitT family COG1284; Uncharacterized protein conserved in bacteria (DUF2179). (285 aa)
AGL03808.1PFAM: MreB/Mbl protein; TIGRFAM: cell shape determining protein, MreB/Mrl family. (350 aa)
murA-2UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. (418 aa)
AGL03838.1PFAM: UDP-N-acetylglucosamine 2-epimerase; TIGRFAM: UDP-N-acetylglucosamine 2-epimerase; Belongs to the UDP-N-acetylglucosamine 2-epimerase family. (389 aa)
AGL03854.1Metalloendopeptidase-like membrane protein; PFAM: Peptidase family M23; LysM domain. (301 aa)
murA-3UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. (420 aa)
AGL03954.1Nucleotide sugar dehydrogenase; PFAM: UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain; UDP-glucose/GDP-mannose dehydrogenase family, central domain; UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain; TIGRFAM: nucleotide sugar dehydrogenase; Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. (435 aa)
Your Current Organism:
Desulfallas gibsoniae
NCBI taxonomy Id: 767817
Other names: D. gibsoniae DSM 7213, Desulfallas gibsoniae DSM 7213, Desulfotomaculum gibsoniae DSM 7213, Desulfotomaculum sp. DSM 7213, Desulfotomaculum sp. Groll
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