STRINGSTRING
AGL03954.1 AGL03954.1 AGL03946.1 AGL03946.1 AGL03897.1 AGL03897.1 AGL03892.1 AGL03892.1 AGL03511.1 AGL03511.1 AGL03387.1 AGL03387.1 AGL03296.1 AGL03296.1 AGL03208.1 AGL03208.1 AGL03205.1 AGL03205.1 murB murB AGL02415.1 AGL02415.1 AGL02412.1 AGL02412.1 AGL02224.1 AGL02224.1 AGL02115.1 AGL02115.1 aroE aroE gpsA gpsA AGL01934.1 AGL01934.1 hisD hisD AGL01748.1 AGL01748.1 AGL01622.1 AGL01622.1 AGL01414.1 AGL01414.1 mdh mdh AGL01372.1 AGL01372.1 AGL01350.1 AGL01350.1 guaB guaB dxr dxr AGL01057.1 AGL01057.1 zwf zwf AGL01037.1 AGL01037.1 AGL00982.1 AGL00982.1 AGL00941.1 AGL00941.1 AGL00924.1 AGL00924.1 AGL00920.1 AGL00920.1 AGL00909.1 AGL00909.1 AGL00713.1 AGL00713.1 AGL00712.1 AGL00712.1 AGL00704.1 AGL00704.1 AGL00539.1 AGL00539.1 AGL00446.1 AGL00446.1 AGL00253.1 AGL00253.1 leuB leuB ilvC ilvC AGL00085.1 AGL00085.1 AGL00068.1 AGL00068.1 AGL00046.1 AGL00046.1 AGL00043.1 AGL00043.1 AGK99984.1 AGK99984.1 AGK99640.1 AGK99640.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AGL03954.1Nucleotide sugar dehydrogenase; PFAM: UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain; UDP-glucose/GDP-mannose dehydrogenase family, central domain; UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain; TIGRFAM: nucleotide sugar dehydrogenase; Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. (435 aa)
AGL03946.1Nucleotide sugar dehydrogenase; PFAM: UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain; UDP-glucose/GDP-mannose dehydrogenase family, central domain; UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain; TIGRFAM: nucleotide sugar dehydrogenase. (468 aa)
AGL03897.1PFAM: 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain. (284 aa)
AGL03892.1Isocitrate dehydrogenase, NADP-dependent; PFAM: Isocitrate/isopropylmalate dehydrogenase; TIGRFAM: isocitrate dehydrogenase, NADP-dependent, eukaryotic type; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (401 aa)
AGL03511.1Lactate dehydrogenase-like oxidoreductase; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain; D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain. (339 aa)
AGL03387.1Theronine dehydrogenase-like Zn-dependent dehydrogenase; PFAM: Alcohol dehydrogenase GroES-like domain; Zinc-binding dehydrogenase; TIGRFAM: 2-desacetyl-2-hydroxyethyl bacteriochlorophyllide A dehydrogenase. (344 aa)
AGL03296.1PFAM: 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain. (408 aa)
AGL03208.1Pyrrolysine biosynthesis protein PylD; PFAM: Alanine dehydrogenase/PNT, C-terminal domain; TIGRFAM: pyrrolysine biosynthesis protein PylD. (267 aa)
AGL03205.1PFAM: Malic enzyme, NAD binding domain; Malic enzyme, N-terminal domain; ACT domain; manually curated. (470 aa)
murBUDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation. (303 aa)
AGL02415.1Alcohol dehydrogenase, class IV; PFAM: Iron-containing alcohol dehydrogenase. (387 aa)
AGL02412.1Alcohol dehydrogenase, class IV; PFAM: Iron-containing alcohol dehydrogenase. (382 aa)
AGL02224.1Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. (370 aa)
AGL02115.1PFAM: 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain. (286 aa)
aroEShikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). (313 aa)
gpsAPFAM: NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus; NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family. (355 aa)
AGL01934.1PFAM: Homoserine dehydrogenase, NAD binding domain; Homoserine dehydrogenase; ACT domain. (430 aa)
hisDHistidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. (510 aa)
AGL01748.1PFAM: 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain. (289 aa)
AGL01622.1PFAM: Acetyltransferase (GNAT) family. (202 aa)
AGL01414.1PFAM: Alcohol dehydrogenase GroES-like domain; Zinc-binding dehydrogenase; TIGRFAM: 6-hydroxycyclohex-1-ene-1-carbonyl-CoA dehydrogenase. (359 aa)
mdhMalate dehydrogenase, NAD-dependent; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family. (308 aa)
AGL01372.1PFAM: 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain. (284 aa)
AGL01350.1Hypothetical protein. (210 aa)
guaBInosine-5''-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. (485 aa)
dxr1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. (383 aa)
AGL01057.1PFAM: NAD binding domain of 6-phosphogluconate dehydrogenase; 6-phosphogluconate dehydrogenase, C-terminal domain; TIGRFAM: 6-phosphogluconate dehydrogenase (decarboxylating); 6-phosphogluconate dehydrogenase, decarboxylating. (298 aa)
zwfGlucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. (523 aa)
AGL01037.1Nucleotide sugar dehydrogenase; PFAM: UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain; UDP-glucose/GDP-mannose dehydrogenase family, central domain; UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain; TIGRFAM: nucleotide sugar dehydrogenase. (432 aa)
AGL00982.1Alcohol dehydrogenase, class IV; PFAM: Iron-containing alcohol dehydrogenase. (390 aa)
AGL00941.1PFAM: Acetyltransferase (GNAT) family. (201 aa)
AGL00924.1Lactate dehydrogenase-like oxidoreductase; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain; D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain. (331 aa)
AGL00920.1PFAM: 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain. (285 aa)
AGL00909.1Phosphoglycerate dehydrogenase-like oxidoreductase; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain; D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain. (329 aa)
AGL00713.1Hypothetical protein. (208 aa)
AGL00712.1Hypothetical protein. (216 aa)
AGL00704.1PFAM: Malic enzyme, NAD binding domain; Malic enzyme, N-terminal domain. (480 aa)
AGL00539.1Alcohol dehydrogenase, class IV; PFAM: Iron-containing alcohol dehydrogenase. (388 aa)
AGL00446.1Alcohol dehydrogenase, class IV; PFAM: Aldehyde dehydrogenase family; Iron-containing alcohol dehydrogenase; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family. (872 aa)
AGL00253.1Alcohol dehydrogenase, class IV; PFAM: Iron-containing alcohol dehydrogenase. (384 aa)
leuB3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. (358 aa)
ilvCKetol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (331 aa)
AGL00085.1Alcohol dehydrogenase, class IV; PFAM: Iron-containing alcohol dehydrogenase. (383 aa)
AGL00068.1PFAM: 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain. (287 aa)
AGL00046.1PFAM: 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain. (285 aa)
AGL00043.1PFAM: 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain. (292 aa)
AGK99984.1PFAM: Enoyl-CoA hydratase/isomerase family; 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain. (807 aa)
AGK99640.1PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain; ACT domain; D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain; TIGRFAM: D-3-phosphoglycerate dehydrogenase. (529 aa)
Your Current Organism:
Desulfallas gibsoniae
NCBI taxonomy Id: 767817
Other names: D. gibsoniae DSM 7213, Desulfallas gibsoniae DSM 7213, Desulfotomaculum gibsoniae DSM 7213, Desulfotomaculum sp. DSM 7213, Desulfotomaculum sp. Groll
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