(22 nodes) Butanoate metabolism network (Fusobacterium nucleatum polymorphum)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ALM94478.1	Sodium pump decarboxylase; Catalyzes the decarboxylation of oxaloacetate coupled to Na(+) translocation; Belongs to the OadG family. (108 aa)
	ALM94473.1	glutaconyl-CoA decarboxylase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology. (584 aa)
	ALM94474.1	Glutaconate CoA-transferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (267 aa)
	ALM94475.1	Glutaconate CoA-transferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (321 aa)
	ALM94476.1	glutaconyl-CoA decarboxylase subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology. (380 aa)
	ALM94477.1	acetyl-CoA carboxylase biotin carboxyl carrier protein subunit; Derived by automated computational analysis using gene prediction method: Protein Homology. (134 aa)
	ALM94597.1	Acetate CoA-transferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (221 aa)
	ALM94598.1	Branched-chain amino acid dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (217 aa)
	ALM94985.1	Acetolactate synthase small subunit; Derived by automated computational analysis using gene prediction method: Protein Homology. (162 aa)
	ALM93587.1	acyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (381 aa)
	ALM93794.1	Glutamate decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the group II decarboxylase family. (459 aa)
	ALM93820.1	3-hydroxybutyryl-CoA dehydrogenase; Converts (S)-3-hydroxybutanoyl-CoA to 3-acetoacetyl-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology. (279 aa)
	ALM93821.1	enoyl-CoA hydratase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the enoyl-CoA hydratase/isomerase family. (258 aa)
	nifJ	Pyruvate-flavodoxin oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (1191 aa)
	pflB	Formate acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (743 aa)
	ALM93382.1	4-hydroxybutyrate CoA-transferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (434 aa)
	ALM93264.1	acetyl-CoA acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Thiolase family. (402 aa)
	ALM95325.1	Pyruvate-flavodoxin oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (1188 aa)
	ALM95223.1	acyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (378 aa)
	ALM95051.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (482 aa)
	ALM95009.1	Fumarate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (573 aa)
	ilvB	Acetolactate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (573 aa)

Your Current Organism:

Fusobacterium nucleatum polymorphum

NCBI taxonomy Id: 76857
Other names: ATCC 10953, CCUG 9126, DSM 20482, F. nucleatum subsp. polymorphum, Fusibacterium nucleatum subsp. polymorphum, Fusobacterium nucleatum subsp. polymorphum, Fusobacterium polymorphum, JCM 12990, NCTC 10562

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ALM93264.1	ALM93382.1	RO02_01120	RO02_01755	acetyl-CoA acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Thiolase family.	4-hydroxybutyrate CoA-transferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.744
ALM93264.1	ALM93587.1	RO02_01120	RO02_02825	acetyl-CoA acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Thiolase family.	acyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.931
ALM93264.1	ALM93820.1	RO02_01120	RO02_04035	acetyl-CoA acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Thiolase family.	3-hydroxybutyryl-CoA dehydrogenase; Converts (S)-3-hydroxybutanoyl-CoA to 3-acetoacetyl-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.999
ALM93264.1	ALM93821.1	RO02_01120	RO02_04040	acetyl-CoA acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Thiolase family.	enoyl-CoA hydratase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the enoyl-CoA hydratase/isomerase family.	0.999
ALM93264.1	ALM94473.1	RO02_01120	RO02_07525	acetyl-CoA acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Thiolase family.	glutaconyl-CoA decarboxylase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.833
ALM93264.1	ALM94474.1	RO02_01120	RO02_07530	acetyl-CoA acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Thiolase family.	Glutaconate CoA-transferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.555
ALM93264.1	ALM94475.1	RO02_01120	RO02_07535	acetyl-CoA acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Thiolase family.	Glutaconate CoA-transferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.545
ALM93264.1	ALM94477.1	RO02_01120	RO02_07545	acetyl-CoA acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Thiolase family.	acetyl-CoA carboxylase biotin carboxyl carrier protein subunit; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.780
ALM93264.1	ALM94597.1	RO02_01120	RO02_08185	acetyl-CoA acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Thiolase family.	Acetate CoA-transferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.727
ALM93264.1	ALM94598.1	RO02_01120	RO02_08190	acetyl-CoA acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Thiolase family.	Branched-chain amino acid dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.753
ALM93264.1	ALM95009.1	RO02_01120	RO02_10525	acetyl-CoA acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Thiolase family.	Fumarate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.824
ALM93264.1	ALM95223.1	RO02_01120	RO02_11830	acetyl-CoA acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Thiolase family.	acyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.866
ALM93264.1	ALM95325.1	RO02_01120	RO02_12370	acetyl-CoA acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Thiolase family.	Pyruvate-flavodoxin oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.907
ALM93264.1	nifJ	RO02_01120	RO02_04985	acetyl-CoA acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Thiolase family.	Pyruvate-flavodoxin oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.907
ALM93264.1	pflB	RO02_01120	RO02_07175	acetyl-CoA acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Thiolase family.	Formate acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.706
ALM93382.1	ALM93264.1	RO02_01755	RO02_01120	4-hydroxybutyrate CoA-transferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	acetyl-CoA acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Thiolase family.	0.744
ALM93382.1	ALM93820.1	RO02_01755	RO02_04035	4-hydroxybutyrate CoA-transferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	3-hydroxybutyryl-CoA dehydrogenase; Converts (S)-3-hydroxybutanoyl-CoA to 3-acetoacetyl-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.688
ALM93382.1	ALM93821.1	RO02_01755	RO02_04040	4-hydroxybutyrate CoA-transferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	enoyl-CoA hydratase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the enoyl-CoA hydratase/isomerase family.	0.746
ALM93382.1	ALM94473.1	RO02_01755	RO02_07525	4-hydroxybutyrate CoA-transferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	glutaconyl-CoA decarboxylase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.673
ALM93382.1	ALM94477.1	RO02_01755	RO02_07545	4-hydroxybutyrate CoA-transferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	acetyl-CoA carboxylase biotin carboxyl carrier protein subunit; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.666

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