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| | cyoE-1 | Polyprenyltransferase, cytochrome oxidase assembly factor; Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group. (300 aa) |
| | cobA-2 | uroporphyrin-III C-methyltransferase; Belongs to the precorrin methyltransferase family. (211 aa) |
| | fdhD | Formate dehydrogenase delta subunit. (227 aa) |
| | purK | Phosphoribosylaminoimidazole carboxylase. (84 aa) |
| | purK-2 | Phosphoribosylaminoimidazole carboxylase. (64 aa) |
| | nadE | NH(3)-dependent NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source. (275 aa) |
| | rfbC | dTDP-4-dehydrorhamnose 3,5-epimerase; Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose. Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family. (187 aa) |
| | TTX_1340 | P-loop ATPase superfamily protein. (288 aa) |
| | TTX_1345a | Thymidylate kinase family protein. (228 aa) |
| | mthfs | 5-formyltetrahydrofolate cyclo-ligase. (255 aa) |
| | trpA | Tryptophan synthase alpha chain. (244 aa) |
| | trpB-2 | Tryptophan synthase beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (411 aa) |
| | trpD | Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). (328 aa) |
| | trpF | Phosphoribosyl anthranilate isomerase; Belongs to the TrpF family. (210 aa) |
| | acs-3 | Acetyl-coenzyme A synthetase. (565 aa) |
| | TTX_1445 | NUDIX family hydrolase. (140 aa) |
| | oorCA | 2-oxoacid ferredoxin oxidoreductase, gamma-alpha subunit. (565 aa) |
| | polB2 | Possible DNA-directed DNA polymerase. (550 aa) |
| | folE | GTP cyclohydrolase I. (177 aa) |
| | TTX_1469 | Uncharacterized Zn-finger containing protein. (119 aa) |
| | tfb1 | Transcription initiation factor B; Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB). (332 aa) |
| | TTX_1504 | cob(I)alamin adenosyltransferase. (167 aa) |
| | TTX_1508 | Hypothetical protein. (190 aa) |
| | adkA | Adenylate kinase; Belongs to the archaeal adenylate kinase family. (197 aa) |
| | hps | 3-hexulose-6-phosphate synthase. (213 aa) |
| | hemB | Porphobilinogen synthase; Belongs to the ALAD family. (340 aa) |
| | TTX_1556 | Precorrin-2 oxidase / ferrochelatase. (210 aa) |
| | TTX_1556a | Uroporphyrinogen-III synthase. (213 aa) |
| | cobA-3 | uroporphyrin-III C-methyltransferase; Belongs to the precorrin methyltransferase family. (246 aa) |
| | hemL | Glutamate-1-semialdehyde 2,1-aminomutase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily. (424 aa) |
| | hemA | Glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). (405 aa) |
| | hemC | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. (302 aa) |
| | TTX_1561 | cob(I)alamin adenosyltransferase. (189 aa) |
| | priB | Putative DNA primase large subunit; Regulatory subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Stabilizes and modulates the activity of the small subunit, increasing the rate of DNA synthesis, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair. (343 aa) |
| | rpoP | DNA-directed RNA polymerase subunit P; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoP/eukaryotic RPC10 RNA polymerase subunit family. (57 aa) |
| | TTX_1599 | Nicotinamide-nucleotide adenylyltransferase. (166 aa) |
| | mobB | Molybdopterin-guanine dinucleotide biosynthesis protein B. (146 aa) |
| | moeA-3 | Molybdenum cofactor biosynthesis protein. (410 aa) |
| | ppnK | Inorganic polyphosphate/ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (273 aa) |
| | nrdA | Ribonucleoside-diphosphate reductase alpha chain; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen. (845 aa) |
| | serS | Seryl-tRNA synthetase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec). (453 aa) |
| | pyrH | Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. (219 aa) |
| | rpoN | DNA-directed RNA polymerase subunit N; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoN/eukaryotic RPB10 RNA polymerase subunit family. (65 aa) |
| | rpoD | DNA-directed RNA polymerase subunit D; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoD/eukaryotic RPB3 RNA polymerase subunit family. (281 aa) |
| | nusA-2 | N utilization substance protein A; Participates in transcription termination. Belongs to the NusA family. (144 aa) |
| | rpoA2 | DNA-directed RNA polymerase subunit A'; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (378 aa) |
| | rpoA1 | DNA-directed RNA polymerase subunit A; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (883 aa) |
| | rpoB | DNA-directed RNA polymerase subunit B; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1127 aa) |
| | rpoH | DNA-directed RNA polymerase, subunit H; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoH/eukaryotic RPB5 RNA polymerase subunit family. (99 aa) |
| | atpA | H+-transporting A1A0 ATPase subunit A; Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal alpha chain is a catalytic subunit. Belongs to the ATPase alpha/beta chains family. (593 aa) |
| | atpE | H+-transporting A1A0 ATP synthase subunit E. (186 aa) |
| | atpF | H+-transporting A1A0 ATP synthase subunit F, V-type. (96 aa) |
| | rpoK | DNA-directed RNA polymerase subunit K; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoK/eukaryotic RPB6 RNA polymerase subunit family. (112 aa) |
| | elf1 | Transcription elongation factor Elf1, Zn ribbon-containing protein. (97 aa) |
| | gptA-1 | Xanthine-guanine phosphoribosyltransferase. (228 aa) |
| | TTX_1727 | Adenine/guanine phosphoribosyltransferase related PRPP-binding enzyme. (230 aa) |
| | proC | Pyrroline-5-carboxylate reductase. (246 aa) |
| | tfb4 | Transcription initiation factor B. (256 aa) |
| | rpoL | DNA-directed RNA polymerase, subunit L; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoL/eukaryotic RPB11/RPC19 RNA polymerase subunit family. (89 aa) |
| | tktB | Transketolase C-terminal section. (312 aa) |
| | tktA | Transketolase N-terminal section. (250 aa) |
| | oorB-3 | 2-oxoacid ferredoxin oxidoreductase, beta subunit. (315 aa) |
| | oorCA-2 | 2-oxoacid ferredoxin oxidoreductase, gamma-alpha subunit. (635 aa) |
| | acs-2-2 | acetyl-CoA synthetase 2. (668 aa) |
| | moaD-2 | Molybdopterin converting factor, small subunit. (100 aa) |
| | moaD-3 | Molybdopterin converting factor, small subunit. (94 aa) |
| | TTX_1771 | 6-pyruvoyl-tetrahydropterin synthase. (124 aa) |
| | oorC | 2-oxoacid ferredoxin oxidoreductase, gamma subunit. (185 aa) |
| | oorD | 2-oxoacid ferredoxin oxidoreductase, delta subunit. (87 aa) |
| | TTX_1790 | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant. (117 aa) |
| | udp | Uridine phosphorylase. (256 aa) |
| | pyrG | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. (534 aa) |
| | TTX_1820 | Putative phosphoribosyltransferase. (180 aa) |
| | TTX_1833 | GTP:adenosylcobinamide- phosphateguanylyltransferase. (293 aa) |
| | cobO | cob(I)alamin adenosyltransferase. (167 aa) |
| | TTX_1835 | Conserved hypothetical protein, putative NaMN:DMB phosphoribosyltransferase; Belongs to the UPF0284 family. (330 aa) |
| | cobS | Cobalamin (5'-phosphate) synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family. (216 aa) |
| | trpC | Indole-3-glycerol phosphate synthase. (240 aa) |
| | trpE | Anthranilate synthase component I. (419 aa) |
| | TTX_1868 | Predicted nucleotide-utilizing enzyme, competence damage protein (cinA). (261 aa) |
| | TTX_1870 | Nucleotide kinase; Has nucleotide phosphatase activity towards ATP, GTP, CTP, TTP and UTP. May hydrolyze nucleoside diphosphates with lower efficiency; Belongs to the THEP1 NTPase family. (166 aa) |
| | ribH | Riboflavin synthase beta chain; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. (150 aa) |
| | lig1 | DNA ligase; DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair. (592 aa) |
| | cyaB | Adenylate cyclase. (173 aa) |
| | moaC | Molybdenum cofactor biosynthesis protein. (85 aa) |
| | moaC-2 | Molybdenum cofactor biosynthesis protein C. (186 aa) |
| | moaA | Putative molybdopterin cofactor synthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate; Belongs to the radical SAM superfamily. MoaA family. (312 aa) |
| | dnaG | Putative DNA primase DnaG (bacterial type); RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Also part of the exosome, which is a complex involved in RNA degradation. Acts as a poly(A)-binding protein that enhances the interaction between heteropolymeric, adenine-rich transcripts and the exosome. (406 aa) |
| | polB-2 | DNA polymerase II. (785 aa) |
| | tfb3 | Transcription initiation factor B. (160 aa) |
| | tgtA | Queuine tRNA-ribosyltransferase; Exchanges the guanine residue with 7-cyano-7-deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D-loop) of archaeal tRNAs; Belongs to the archaeosine tRNA-ribosyltransferase family. (507 aa) |
| | tfe | Transcription initiation factor E; Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment. Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal. It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing elongation comple [...] (178 aa) |
| | yhhQ1 | Uncharacterized member of the PurR regulon; Involved in the import of queuosine (Q) precursors, required for Q precursor salvage; Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily. (233 aa) |
| | pyrC | Dihydroorotase. (392 aa) |
| | purF | Amidophosphoribosyltransferase; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. (417 aa) |
| | purF-2 | Amidophosphoribosyltransferase. (371 aa) |
| | purQ | Phosphoribosylformylglycinamidine synthase I; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist i [...] (210 aa) |
| | purS | Phosphoribosylformylglycinamidine (FGAM) synthase. (86 aa) |
| | purD | Phosphoribosylamine--glycine ligase. (485 aa) |
| | purC | Phosphoribosylaminoimidazole- succinocarboxamidesynthase; Belongs to the SAICAR synthetase family. (233 aa) |
| | purM | Phosphoribosylformylglycinamidine cyclo-ligase. (307 aa) |
| | folD | Methylenetetrahydrofolate dehydrogenase (NADP+); Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (317 aa) |
| | purN | Phosphoribosylglycinamide formyltransferase. (277 aa) |
| | purK-3 | Phosphoribosylaminoimidazole carboxylase ATPase subunit; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR); Belongs to the PurK/PurT family. (366 aa) |
| | purE | Phosphoribosylaminoimidazole carboxylase catalytic subunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). (152 aa) |
| | purL | Phosphoribosylformylglycinamidine synthase II; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist [...] (700 aa) |
| | folE-2 | GTP cyclohydrolase I. (110 aa) |
| | cmk | Cytidylate kinase. (188 aa) |
| | mtaP | 5'-methylthioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates; Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily. (282 aa) |
| | oorD-2 | 2-oxoacid ferredoxin oxidoreductase, delta subunit. (102 aa) |
| | oorC-2 | 2-oxoacid ferredoxin oxidoreductase, gamma subunit. (173 aa) |
| | thiL | Thiamine monophosphate kinase. (284 aa) |
| | mobA | Molybdopterin-guanine dinucleotide biosynthesis protein A. (266 aa) |
| | rpoF | DNA-directed RNA polymerase subunit F. (110 aa) |
| | tfb2 | Transcription initiation factor B. (300 aa) |
| | moaB | Molybdenum cofactor biosynthesis protein B. (174 aa) |
| | iorB | Indolepyruvate ferredoxin oxidoreductase, beta subunit. (181 aa) |
| | moaDE | Molybdenum cofactor biosynthesis small amd large sunubits. (225 aa) |
| | atpD | A1A0 ATP synthase, subunit D, V-type. (200 aa) |
| | atpC | ATP synthase, subunit C, V-type. (349 aa) |
| | tmk | Thymidylate kinase. (196 aa) |
| | hisA | Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; Belongs to the HisA/HisF family. (235 aa) |
| | TTX_0531 | DNA-directed RNA polymerase, subunit M/Transcription elongation factor TFIIS. (81 aa) |
| | moeA | Molybdenum cofactor biosynthesis protein. (411 aa) |
| | pncB | Nicotinic acid phosphoribosyltransferase. (395 aa) |
| | dfp | Pantothenate metabolism flavoprotein; Unknown EC_number=4.1.1.36 6.3.2.5. (412 aa) |
| | carA | Carbamoyl-phosphate synthase small chain; Belongs to the CarA family. (364 aa) |
| | atpB | H+-transporting A1A0 ATP synthase, subunit B; Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit. (468 aa) |
| | cobA | uroporphyrin-III C-methyltransferase; Belongs to the precorrin methyltransferase family. (217 aa) |
| | cbiA | Cobyrinic acid a,c-diamide synthase. (443 aa) |
| | hemD | uroporphyrinogen-III synthase HemD. (243 aa) |
| | nadM | Nicotinamide-nucleotide adenylyltransferase. (177 aa) |
| | tdk | Thymidine kinase. (178 aa) |
| | TTX_0331 | Uncharacterized protein, putative amidase. (242 aa) |
| | trpB | Tryptophan synthase beta-subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (430 aa) |
| | nadA | Quinolinate synthetase A. (304 aa) |
| | nadB | Aspartate oxidase. (463 aa) |
| | nadC | Nicotinate-nucleotide pyrophosphorylase; Involved in the catabolism of quinolinic acid (QA). Belongs to the NadC/ModD family. (279 aa) |
| | queE | Organic radical activating enzyme; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. (215 aa) |
| | TTX_0290 | Putativ cob(I)alamin adenosyltransferase. (177 aa) |
| | pyrOB | Predicted glutamine amidotransferase involved in pyridoxine biosynthesis; Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS. (203 aa) |
| | snz1 | Pyridoxine biosynthesis enzyme; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5- phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively. Belongs to the PdxS/SNZ family. (339 aa) |
| | thiC | Thiamine biosynthesis protein ThiC. (429 aa) |
| | purB | Adenylosuccinate lyase. (403 aa) |
| | TTX_0263 | Hypothetical protein. (296 aa) |
| | modD | Putative pyrophosphorylase modD; Involved in the catabolism of quinolinic acid (QA). Belongs to the NadC/ModD family. (272 aa) |
| | hemN | Oxygen-independent coproporphyrinogen III oxidase. (415 aa) |
| | oorCD | 2-oxoacid ferredoxin oxidoreductase, gamma-delta subunit. (311 aa) |
| | TTX_0185 | Transcriptional regulator of a riboflavin/FAD biosynthetic operon. (212 aa) |
| | tbp | TATA-box binding protein (Box A binding protein) (TBP); General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation. (203 aa) |
| | polB | polB DNA-directed DNA polymerase I (B1). (860 aa) |
| | ilvB | Acetolactate synthase large subunit. (575 aa) |
| | TTX_0117 | Radical SAM superfamily enzyme. (379 aa) |
| | cbiA-2 | Cobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. (447 aa) |
| | TTX_0010 | Radical SAM superfamily enzyme. (355 aa) |
| | TTX_0062 | Radical SAM superfamily enzyme. (369 aa) |
| | carB | Carbamoyl-phosphate synthase, glutamine dependent, large chain; Belongs to the CarB family. (1018 aa) |
| | guaA | GMP synthase; Catalyzes the synthesis of GMP from XMP. (510 aa) |
| | pyrD | Dihydroorotate dehydrogenase. (297 aa) |
| | pyrE | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). (193 aa) |
| | pyrI | Aspartate carbamoyltransferase, regulatory chain; Involved in allosteric regulation of aspartate carbamoyltransferase. (151 aa) |
| | pyrF | Orotidine-5'-phosphate decarboxylase. (199 aa) |
| | pyrB | Aspartate carbamoyltransferase catalytic chain. (304 aa) |
| | TTX_0829 | Putative nucleotidyltransferase. (150 aa) |
| | thiD | Phosphomethylpyrimidine kinase fused to uncharacterized domain. (450 aa) |
| | TTX_0860 | Diadenosine 5'5'''-P1,P4-tetraphosphate pyrophosphohydrolase (mutT/nudix family protein). (141 aa) |
| | TTX_0892 | Uncharacterized Rossmann fold enzyme. (205 aa) |
| | thyX | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant. (244 aa) |
| | nusA | Transcription elongation factor NusA. (172 aa) |
| | upp | Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. (210 aa) |
| | TTX_0999 | CMP/ AMP kinase related enzyme; Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. Belongs to the adenylate kinase family. AK6 subfamily. (191 aa) |
| | prsA | Ribose-phosphate pyrophosphokinase; Belongs to the ribose-phosphate pyrophosphokinase family. (288 aa) |
| | TTX_1008 | Amidase related protein. (228 aa) |
| | ribD | 5-amino-6-(5- phosphoribosylamino)uracilreductase. (217 aa) |
| | ribB | GTP cyclohydrolase II. (216 aa) |
| | acd-2 | acyl-CoA dehydrogenase. (410 aa) |
| | TTX_1080 | Sugar kinase superfamily enzyme. (285 aa) |
| | TTX_1081 | Conserved hypothetical protein. (264 aa) |
| | apbA | 2-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. (279 aa) |
| | cbiG | Cobalamin biosynthesis protein G. (314 aa) |
| | cbiE | Cobalamin biosynthesis precorrin-6Y methylase. (203 aa) |
| | panB | 3-methyl-2-oxobutanoatehydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. (265 aa) |
| | TTX_0077 | Metallo-beta-lactamase family protein. (260 aa) |
| | cbiC | precorrin-8X methylmutase fused to uncharacterized domain. (335 aa) |
| | cbiF | Cobalamin biosynthesis precorrin-3 methylase. (245 aa) |
| | cbiD | Cobalamin biosynthesis protein D; Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A. (341 aa) |
| | cbiT | Cobalamin biosynthesis precorrin-8W decarboxylase; Catalyzes the methylation of C-15 in cobalt-precorrin-6B followed by the decarboxylation of C-12 to form cobalt-precorrin-7. (189 aa) |
| | cbiF-2 | Cobalamin biosynthesis precorrin-3 methylase; Belongs to the precorrin methyltransferase family. (206 aa) |
| | cbiF-3 | Precorrin-4 C11-methyltransferase; Belongs to the precorrin methyltransferase family. (258 aa) |
| | acsA | Acetyl-coenzyme A synthetase. (628 aa) |
| | acd-4 | acyl-CoA dehydrogenase. (382 aa) |
| | acs-2 | acetyl-CoA synthetase 2. (666 aa) |
| | moeA-2 | moeA-like molybdenum cofactor biosynthesis domain fused to molybdate-binding domain. (639 aa) |
| | pflA | Pyruvate formate-lyase activating enzyme. (236 aa) |
| | purA | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. (334 aa) |
| | TTX_0540 | ACT domain protein; Belongs to the UPF0237 family. (90 aa) |
| | TTX_0542 | 5-formaminoimidazole-4-carboxamide-1-beta-D- ribofuranosyl 5'-monophosphate synthetase. (347 aa) |
| | TTX_0543 | 5-formaminoimidazole-4-carboxamide-1-beta-D- ribofuranosyl 5'-monophosphate synthetase. (335 aa) |
| | TTX_0546 | Conserved hypothetical protein; Catalyzes the GTP-dependent phosphorylation of the 3'- hydroxyl group of dephosphocoenzyme A to form coenzyme A (CoA). (169 aa) |
| | acs-4 | acetyl-CoA synthetase. (629 aa) |
| | acd | acyl-CoA dehydrogenase. (380 aa) |
| | priS | DNA primase small subunit; Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. [...] (316 aa) |
| | tfs/rpoM | Archaeal transcription elongation factor TFS/RNA polymerase subunit M; Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (109 aa) |
| | rpoE1 | DNA-directed RNA polymerase, subunit E'. (189 aa) |
| | snt-6 | Sugar phosphate nucleotidyltransferase. (360 aa) |
| | thiI | Thiazole biosynthesis protein Thi I; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. (472 aa) |
| | nadE1 | NH(3)-dependent NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source. (281 aa) |
| | TTX_0669 | Riboflavin synthase. (151 aa) |
| | dcd | Deoxycytidine triphosphate deaminase; Catalyzes the deamination of dCTP to dUTP. (179 aa) |
| | moaD | Molybdopterin converting factor, small subunit. (89 aa) |
| | TTX_0692 | Cobalamin biosynthesis protein CobD/CbiB. (296 aa) |
| | TTX_0711 | DNA-directed RNA polymerase, subunit M/Transcription elongation factor TFIIS. (89 aa) |
