(12 nodes) U4/U6 x U5 tri-snRNP complex network (Malassezia pachydermatis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Malapachy_1750	P-loop containing nucleoside triphosphate hydrolase protein. (990 aa)
	Malapachy_2078	Spliceosomal protein DIB1; Essential role in pre-mRNA splicing. Also essential for entry into mitosis (G2/M progression) as well as for chromosome segregation during mitosis; Belongs to the DIM1 family. (142 aa)
	Malapachy_2116	Pre-mrna splicing factor prp1. (925 aa)
	Malapachy_0053	Sec63-domain-containing protein. (2161 aa)
	Malapachy_0264	Uncharacterized protein. (793 aa)
	Malapachy_2633	U5 snrnp complex subunit. (357 aa)
	Malapachy_3626	Nop domain-containing protein. (550 aa)
	Malapachy_2919	Pre-mrna-processing-splicing factor. (2372 aa)
	Malapachy_3392	Wd40 repeat-like protein. (504 aa)
	Malapachy_3713	Prp3-domain-containing protein. (548 aa)
	LSM8	U6 snRNA-associated Sm-like protein LSm8; Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA. (96 aa)
	Malapachy_1992	Pre-mrna-splicing atp-dependent rna helicase prp28; Belongs to the DEAD box helicase family. (602 aa)

Your Current Organism:

Malassezia pachydermatis

NCBI taxonomy Id: 77020
Other names: M. pachydermatis, Pityrosporum pachydermatis

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LSM8	Malapachy_0053	A0A0M9VPK5	A0A0M8MSN8	U6 snRNA-associated Sm-like protein LSm8; Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA.	Sec63-domain-containing protein.	0.992
LSM8	Malapachy_0264	A0A0M9VPK5	A0A0M8MT84	U6 snRNA-associated Sm-like protein LSm8; Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA.	Uncharacterized protein.	0.993
LSM8	Malapachy_1750	A0A0M9VPK5	A0A0M8MNG0	U6 snRNA-associated Sm-like protein LSm8; Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA.	P-loop containing nucleoside triphosphate hydrolase protein.	0.991
LSM8	Malapachy_1992	A0A0M9VPK5	A0A0N0RS52	U6 snRNA-associated Sm-like protein LSm8; Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA.	Pre-mrna-splicing atp-dependent rna helicase prp28; Belongs to the DEAD box helicase family.	0.794
LSM8	Malapachy_2078	A0A0M9VPK5	A0A0M8MNU9	U6 snRNA-associated Sm-like protein LSm8; Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA.	Spliceosomal protein DIB1; Essential role in pre-mRNA splicing. Also essential for entry into mitosis (G2/M progression) as well as for chromosome segregation during mitosis; Belongs to the DIM1 family.	0.966
LSM8	Malapachy_2116	A0A0M9VPK5	A0A0M8MP07	U6 snRNA-associated Sm-like protein LSm8; Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA.	Pre-mrna splicing factor prp1.	0.990
LSM8	Malapachy_2633	A0A0M9VPK5	A0A0M8MW60	U6 snRNA-associated Sm-like protein LSm8; Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA.	U5 snrnp complex subunit.	0.770
LSM8	Malapachy_2919	A0A0M9VPK5	A0A0M8MYF1	U6 snRNA-associated Sm-like protein LSm8; Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA.	Pre-mrna-processing-splicing factor.	0.990
LSM8	Malapachy_3392	A0A0M9VPK5	A0A0M8MYI4	U6 snRNA-associated Sm-like protein LSm8; Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA.	Wd40 repeat-like protein.	0.994
LSM8	Malapachy_3626	A0A0M9VPK5	A0A0M8MXN2	U6 snRNA-associated Sm-like protein LSm8; Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA.	Nop domain-containing protein.	0.995
LSM8	Malapachy_3713	A0A0M9VPK5	A0A0M9VP75	U6 snRNA-associated Sm-like protein LSm8; Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA.	Prp3-domain-containing protein.	0.994
Malapachy_0053	LSM8	A0A0M8MSN8	A0A0M9VPK5	Sec63-domain-containing protein.	U6 snRNA-associated Sm-like protein LSm8; Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA.	0.992
Malapachy_0053	Malapachy_0264	A0A0M8MSN8	A0A0M8MT84	Sec63-domain-containing protein.	Uncharacterized protein.	0.996
Malapachy_0053	Malapachy_1750	A0A0M8MSN8	A0A0M8MNG0	Sec63-domain-containing protein.	P-loop containing nucleoside triphosphate hydrolase protein.	0.999
Malapachy_0053	Malapachy_1992	A0A0M8MSN8	A0A0N0RS52	Sec63-domain-containing protein.	Pre-mrna-splicing atp-dependent rna helicase prp28; Belongs to the DEAD box helicase family.	0.982
Malapachy_0053	Malapachy_2078	A0A0M8MSN8	A0A0M8MNU9	Sec63-domain-containing protein.	Spliceosomal protein DIB1; Essential role in pre-mRNA splicing. Also essential for entry into mitosis (G2/M progression) as well as for chromosome segregation during mitosis; Belongs to the DIM1 family.	0.997
Malapachy_0053	Malapachy_2116	A0A0M8MSN8	A0A0M8MP07	Sec63-domain-containing protein.	Pre-mrna splicing factor prp1.	0.997
Malapachy_0053	Malapachy_2633	A0A0M8MSN8	A0A0M8MW60	Sec63-domain-containing protein.	U5 snrnp complex subunit.	0.994
Malapachy_0053	Malapachy_2919	A0A0M8MSN8	A0A0M8MYF1	Sec63-domain-containing protein.	Pre-mrna-processing-splicing factor.	0.999
Malapachy_0053	Malapachy_3392	A0A0M8MSN8	A0A0M8MYI4	Sec63-domain-containing protein.	Wd40 repeat-like protein.	0.995