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Malapachy_1591 Malapachy_1591 Malapachy_1770 Malapachy_1770 Malapachy_2560 Malapachy_2560 Malapachy_3032 Malapachy_3032 Malapachy_1481 Malapachy_1481 Malapachy_4091 Malapachy_4091 Malapachy_2292 Malapachy_2292 Malapachy_3420 Malapachy_3420 Malapachy_3215 Malapachy_3215 Malapachy_0384 Malapachy_0384 Malapachy_2462 Malapachy_2462 Malapachy_1066 Malapachy_1066 Malapachy_1259 Malapachy_1259 KAE1 KAE1 Malapachy_3826 Malapachy_3826 Malapachy_0697 Malapachy_0697 Malapachy_0871 Malapachy_0871 Malapachy_2452 Malapachy_2452
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Malapachy_1591Serine-protein kinase atr; Belongs to the PI3/PI4-kinase family. (2337 aa)
Malapachy_1770ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. (737 aa)
Malapachy_2560Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. It elongates telomeres. It is a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. (981 aa)
Malapachy_3032Uncharacterized protein. (455 aa)
Malapachy_1481Dna replication helicase. (1171 aa)
Malapachy_4091ATP-dependent DNA helicase; Belongs to the helicase family. (531 aa)
Malapachy_2292Spoc domain-like protein. (696 aa)
Malapachy_3420Rnapii degradation factor def1. (791 aa)
Malapachy_3215Telomere_reg-2 domain-containing protein. (957 aa)
Malapachy_0384HABP4_PAI-RBP1 domain-containing protein. (285 aa)
Malapachy_2462Ku70-like protein. (650 aa)
Malapachy_1066Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism. (617 aa)
Malapachy_1259Rad51 domain-containing protein. (473 aa)
KAE1tRNA N6-adenosine threonylcarbamoyltransferase; Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. KAE1 likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity. The EKC/KEOPS complex also promotes both telomere uncapping and telomere elongation. Th [...] (394 aa)
Malapachy_3826Uncharacterized protein; Belongs to the CGI121/TPRKB family. (224 aa)
Malapachy_0697Dna repair protein rad50. (1292 aa)
Malapachy_0871Translation factor. (455 aa)
Malapachy_2452POT1PC domain-containing protein. (633 aa)
Your Current Organism:
Malassezia pachydermatis
NCBI taxonomy Id: 77020
Other names: M. pachydermatis, Pityrosporum pachydermatis
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