node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
MCM7 | Malapachy_0759 | A0A0M8MTI6 | A0A0M8MVR0 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | DNA helicase; Belongs to the MCM family. | 0.999 |
MCM7 | Malapachy_1066 | A0A0M8MTI6 | A0A0M8MN58 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism. | 0.822 |
MCM7 | Malapachy_1133 | A0A0M8MTI6 | A0A0M8MVP7 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | Anti-silencing protein 1. | 0.623 |
MCM7 | Malapachy_3240 | A0A0M8MTI6 | A0A0M9VQT5 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | Rfa2-dna replication factor 36 kDa subunit. | 0.783 |
MCM7 | Malapachy_3255 | A0A0M8MTI6 | A0A0M8MSJ7 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | DNA helicase; Belongs to the MCM family. | 0.999 |
Malapachy_0179 | Malapachy_1066 | A0A0M8MTF8 | A0A0M8MN58 | Cullin 4a; Belongs to the cullin family. | Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism. | 0.587 |
Malapachy_0358 | Malapachy_3826 | A0A0M9VMU5 | A0A0M8MPV7 | P53-related protein kinase. | Uncharacterized protein; Belongs to the CGI121/TPRKB family. | 0.997 |
Malapachy_0441 | Malapachy_0805 | A0A0N0RRZ2 | A0A0M9VPV3 | Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. | Uncharacterized protein. | 0.681 |
Malapachy_0441 | Malapachy_1133 | A0A0N0RRZ2 | A0A0M8MVP7 | Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. | Anti-silencing protein 1. | 0.601 |
Malapachy_0441 | Malapachy_2292 | A0A0N0RRZ2 | A0A0M9VQB2 | Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. | Spoc domain-like protein. | 0.566 |
Malapachy_0441 | Malapachy_2299 | A0A0N0RRZ2 | A0A0M8MRJ1 | Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. | Dhs-like nad fad-binding domain-containing protein. | 0.407 |
Malapachy_0441 | Malapachy_2462 | A0A0N0RRZ2 | A0A0M8MM81 | Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. | Ku70-like protein. | 0.629 |
Malapachy_0759 | MCM7 | A0A0M8MVR0 | A0A0M8MTI6 | DNA helicase; Belongs to the MCM family. | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | 0.999 |
Malapachy_0759 | Malapachy_1066 | A0A0M8MVR0 | A0A0M8MN58 | DNA helicase; Belongs to the MCM family. | Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism. | 0.851 |
Malapachy_0759 | Malapachy_3240 | A0A0M8MVR0 | A0A0M9VQT5 | DNA helicase; Belongs to the MCM family. | Rfa2-dna replication factor 36 kDa subunit. | 0.821 |
Malapachy_0759 | Malapachy_3255 | A0A0M8MVR0 | A0A0M8MSJ7 | DNA helicase; Belongs to the MCM family. | DNA helicase; Belongs to the MCM family. | 0.999 |
Malapachy_0805 | Malapachy_0441 | A0A0M9VPV3 | A0A0N0RRZ2 | Uncharacterized protein. | Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. | 0.681 |
Malapachy_0805 | Malapachy_2299 | A0A0M9VPV3 | A0A0M8MRJ1 | Uncharacterized protein. | Dhs-like nad fad-binding domain-containing protein. | 0.440 |
Malapachy_0805 | Malapachy_2560 | A0A0M9VPV3 | A0A0M8MX46 | Uncharacterized protein. | Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. It elongates telomeres. It is a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. | 0.530 |
Malapachy_1066 | MCM7 | A0A0M8MN58 | A0A0M8MTI6 | Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism. | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | 0.822 |