101 items (Malassezia pachydermatis) - STRING interaction network

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Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Malapachy_2077	Tpr-like protein. (858 aa)
	Malapachy_3925	Uncharacterized protein. (708 aa)
	Malapachy_1873	Ino80-atpase with chromatin remodeling and helicase activity. (1408 aa)
	Malapachy_1925	Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (103 aa)
	Malapachy_2029	Putative set3 histone deacetylase complex component snt1p. (914 aa)
	Malapachy_1678	JmjC domain-containing protein. (415 aa)
	Malapachy_0073	Actin-like protein arp6; Belongs to the actin family. (485 aa)
	Malapachy_1645	Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (525 aa)
	Malapachy_1470	Dna polymerase eta. (654 aa)
	Malapachy_0592	Phd zn-finger protein. (601 aa)
	Malapachy_0411	Mis18 domain-containing protein. (238 aa)
	Malapachy_2855	Nuclear cohesin complex subunit. (1079 aa)
	Malapachy_0398	Bromodomain-containing protein. (744 aa)
	Malapachy_0321	Histone h1. (208 aa)
	Malapachy_2832	Yl1-domain-containing protein. (568 aa)
	Malapachy_3344	Set domain-containing protein; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. SET2 subfamily. (696 aa)
	Malapachy_2385	Snf2 family dna-dependent atpase. (884 aa)
	Malapachy_3359	Uncharacterized protein. (438 aa)
	Malapachy_0869	Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (509 aa)
	Malapachy_4027	Cyclophilin-like protein. (263 aa)
	Malapachy_1909	Histone H3; Belongs to the histone H3 family. (136 aa)
	Malapachy_1736	Rrp6-exonuclease component of the nuclear exosome. (842 aa)
	Malapachy_1815	F-box-like wd repeat-containing protein tbl1xr1-like protein. (639 aa)
	Malapachy_0058	P-loop containing nucleoside triphosphate hydrolase protein. (1075 aa)
	Malapachy_0118	Swi snf complex 60 kDa subunit. (544 aa)
	Malapachy_0079	Cohesin-associated protein pds5. (1062 aa)
	Malapachy_3355	Protein containing the rna recognition motif. (630 aa)
	Malapachy_3593	Fact complex subunit spt16. (584 aa)
	Malapachy_0179	Cullin 4a; Belongs to the cullin family. (608 aa)
	Malapachy_3263	Heat repeat protein. (1296 aa)
	Malapachy_3072	RuvB-like helicase; DNA helicase participates in several chromatin remodeling complexes, including the SWR1 and the INO80 complexes. (490 aa)
	Malapachy_0004	Polymerase iii polypeptide h. (233 aa)
	Malapachy_2797	Exosome complex exonuclease rrp4. (348 aa)
	Malapachy_0327	FK506-binding protein. (454 aa)
	Malapachy_2469	Nucleosome assembly protein; Belongs to the nucleosome assembly protein (NAP) family. (427 aa)
	Malapachy_2311	DNA polymerase epsilon subunit; Participates in DNA repair and in chromosomal DNA replication; Belongs to the DNA polymerase epsilon subunit B family. (562 aa)
	Malapachy_1344	Histone H2A; Belongs to the histone H2A family. (136 aa)
	Malapachy_2334	Vezatin domain-containing protein. (763 aa)
	Malapachy_3429	Serine/threonine-protein phosphatase. (327 aa)
	Malapachy_1182	Cmgc cdk cdk7 protein kinase; Belongs to the protein kinase superfamily. (370 aa)
	Malapachy_3632	Helicase swr1. (1467 aa)
	Malapachy_3747	Set protein (Protein phosphatase 2a inhibitor); Belongs to the nucleosome assembly protein (NAP) family. (272 aa)
	Malapachy_2517	Structural maintenance of chromosomes protein. (1212 aa)
	KAE1	tRNA N6-adenosine threonylcarbamoyltransferase; Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. KAE1 likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity. The EKC/KEOPS complex also promotes both telomere uncapping and telomere elongation. Th [...] (394 aa)
	Malapachy_3354	Kelch repeat protein. (950 aa)
	Malapachy_4156	Snf5-domain-containing protein; Belongs to the universal ribosomal protein uS2 family. (1506 aa)
	Malapachy_0199	Camp-dependent protein kinase regulatory subunit. (571 aa)
	Malapachy_0065	Histone deacetylation-related protein. (1166 aa)
	Malapachy_1540	Histone-fold-containing protein. (123 aa)
	Malapachy_0666	YL1_C domain-containing protein. (176 aa)
	Malapachy_0458	Bromodomain containing protein. (451 aa)
	Malapachy_2654	Ubiquitin-conjugating enzyme; Belongs to the ubiquitin-conjugating enzyme family. (161 aa)
	Malapachy_3978	Act1-actin; Belongs to the actin family. (475 aa)
	Malapachy_2756	Histone H3; Belongs to the histone H3 family. (136 aa)
	Malapachy_0664	Yeats family protein. (321 aa)
	Malapachy_1418	Pre-mrna-splicing factor clf1. (721 aa)
	Malapachy_1940	Actin-related protein 8; Probably involved in transcription regulation via its interaction with the INO80 complex, a chromatin remodeling complex. Belongs to the actin family. (790 aa)
	Malapachy_0024	ARID domain-containing protein. (1006 aa)
	Malapachy_0495	Yt521-b-like splicing protein. (144 aa)
	Malapachy_3555	Snf2-family atp dependent chromatin remodeling factor snf21. (1432 aa)
	Malapachy_2974	RuvB-like helicase; DNA helicase participates in several chromatin remodeling complexes, including the SWR1 and the INO80 complexes. (452 aa)
	Malapachy_3250	26s proteasome subunit p45; Belongs to the AAA ATPase family. (428 aa)
	Malapachy_2091	PAPA-1 domain-containing protein. (296 aa)
	Malapachy_2300	Rsc complex protein. (592 aa)
	Malapachy_2577	Mrg-domain-containing protein. (362 aa)
	Malapachy_2250	Swr1-complex protein 5. (92 aa)
	Malapachy_2195	Uncharacterized protein. (661 aa)
	Malapachy_2534	Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (475 aa)
	Malapachy_1238	Swi snf complex protein. (993 aa)
	Malapachy_1165	Rsc complex member. (651 aa)
	Malapachy_1108	Hcngp-domain-containing protein. (178 aa)
	Malapachy_4038	Uncharacterized protein. (565 aa)
	Malapachy_0979	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (297 aa)
	Malapachy_4082	Uncharacterized protein. (341 aa)
	Malapachy_0636	Uncharacterized protein. (849 aa)
	Malapachy_1223	Ccch zinc finger protein. (439 aa)
	Malapachy_0797	Histone H2A; Belongs to the histone H2A family. (136 aa)
	Malapachy_0639	Phd zn-finger protein. (580 aa)
	Malapachy_1160	Histone-fold-containing protein. (224 aa)
	Malapachy_0991	Swc4-component of the swr1p complex. (533 aa)
	Malapachy_0805	Uncharacterized protein. (748 aa)
	Malapachy_1155	Uncharacterized protein. (548 aa)
	Malapachy_2481	Chromodomain-helicase dna-binding protein. (1408 aa)
	Malapachy_2461	E3 ubiquitin protein ligase. (750 aa)
	Malapachy_2552	Ims-domain-containing protein. (538 aa)
	Malapachy_3462	RNase_PH domain-containing protein. (266 aa)
	MED10	Mediator of RNA polymerase II transcription subunit 10; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (178 aa)
	Malapachy_3683	Transcription factor. (708 aa)
	Malapachy_3473	Rna polymerase ii associated paf1 complex. (521 aa)
	Malapachy_2928	Aaa-domain-containing protein. (1283 aa)
	Malapachy_3098	Arsenite-resistant protein asr2. (513 aa)
	Malapachy_3288	Uncharacterized protein. (186 aa)
	Malapachy_3342	Chromatin remodelling complex atpase chain isw1. (1021 aa)
	Malapachy_0379	Uncharacterized protein. (568 aa)
	Malapachy_1324	JmjC domain-containing protein. (441 aa)
	Malapachy_1316	Uncharacterized protein. (303 aa)
	Malapachy_1411	Chromatin modification-related protein. (454 aa)
	Malapachy_0460	Uncharacterized protein. (406 aa)
	Malapachy_0441	Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (264 aa)
	Malapachy_1244	Chromatin remodeling complex subunit; Belongs to the actin family. (743 aa)
	Malapachy_0811	Histone h2b; Belongs to the histone H2B family. (140 aa)

Your Current Organism:

Malassezia pachydermatis

NCBI taxonomy Id: 77020
Other names: M. pachydermatis, Pityrosporum pachydermatis

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
MED10	Malapachy_0811	A0A0M9VQW2	A0A0N0RSF6	Mediator of RNA polymerase II transcription subunit 10; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	Histone h2b; Belongs to the histone H2B family.	0.525
MED10	Malapachy_1182	A0A0M9VQW2	A0A0M8MQU6	Mediator of RNA polymerase II transcription subunit 10; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	Cmgc cdk cdk7 protein kinase; Belongs to the protein kinase superfamily.	0.545
MED10	Malapachy_1344	A0A0M9VQW2	A0A0M8MRA9	Mediator of RNA polymerase II transcription subunit 10; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	Histone H2A; Belongs to the histone H2A family.	0.495
MED10	Malapachy_1925	A0A0M9VQW2	A0A0M9VNS6	Mediator of RNA polymerase II transcription subunit 10; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.	0.403
Malapachy_0024	Malapachy_0118	A0A0M8MJ62	A0A0M8MTX8	ARID domain-containing protein.	Swi snf complex 60 kDa subunit.	0.883
Malapachy_0024	Malapachy_0664	A0A0M8MJ62	A0A0M8MKZ4	ARID domain-containing protein.	Yeats family protein.	0.424
Malapachy_0024	Malapachy_0797	A0A0M8MJ62	A0A0M9VPN2	ARID domain-containing protein.	Histone H2A; Belongs to the histone H2A family.	0.553
Malapachy_0024	Malapachy_0805	A0A0M8MJ62	A0A0M9VPV3	ARID domain-containing protein.	Uncharacterized protein.	0.691
Malapachy_0024	Malapachy_0811	A0A0M8MJ62	A0A0N0RSF6	ARID domain-containing protein.	Histone h2b; Belongs to the histone H2B family.	0.424
Malapachy_0024	Malapachy_0869	A0A0M8MJ62	A0A0M8MUD4	ARID domain-containing protein.	Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily.	0.702
Malapachy_0024	Malapachy_1165	A0A0M8MJ62	A0A0M8MVP0	ARID domain-containing protein.	Rsc complex member.	0.584
Malapachy_0024	Malapachy_1238	A0A0M8MJ62	A0A0M8MVS1	ARID domain-containing protein.	Swi snf complex protein.	0.883
Malapachy_0024	Malapachy_1540	A0A0M8MJ62	A0A0M8MMN7	ARID domain-containing protein.	Histone-fold-containing protein.	0.713
Malapachy_0024	Malapachy_1645	A0A0M8MJ62	A0A0M9VNE4	ARID domain-containing protein.	Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily.	0.702
Malapachy_0024	Malapachy_1873	A0A0M8MJ62	A0A0M9VP13	ARID domain-containing protein.	Ino80-atpase with chromatin remodeling and helicase activity.	0.509
Malapachy_0024	Malapachy_1909	A0A0M8MJ62	A0A0M8MU86	ARID domain-containing protein.	Histone H3; Belongs to the histone H3 family.	0.713
Malapachy_0024	Malapachy_1925	A0A0M8MJ62	A0A0M9VNS6	ARID domain-containing protein.	Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.	0.721
Malapachy_0024	Malapachy_2300	A0A0M8MJ62	A0A0M8MX96	ARID domain-containing protein.	Rsc complex protein.	0.584
Malapachy_0024	Malapachy_2481	A0A0M8MJ62	A0A0M9VQ92	ARID domain-containing protein.	Chromodomain-helicase dna-binding protein.	0.516
Malapachy_0024	Malapachy_2577	A0A0M8MJ62	A0A0M8MX78	ARID domain-containing protein.	Mrg-domain-containing protein.	0.638