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Malapachy_3595 Malapachy_3595 ERG11 ERG11 Malapachy_0291 Malapachy_0291 Malapachy_0486 Malapachy_0486 Malapachy_1482 Malapachy_1482 Malapachy_0092 Malapachy_0092 Malapachy_0188 Malapachy_0188 Malapachy_1764 Malapachy_1764 Malapachy_4209 Malapachy_4209 Malapachy_1626 Malapachy_1626 Malapachy_4241 Malapachy_4241 Malapachy_0138 Malapachy_0138 Malapachy_1989 Malapachy_1989 Malapachy_2793 Malapachy_2793 Malapachy_4087 Malapachy_4087 Malapachy_0524 Malapachy_0524 Malapachy_2488 Malapachy_2488 Malapachy_3980 Malapachy_3980 Malapachy_1100 Malapachy_1100 Malapachy_1537 Malapachy_1537 Malapachy_1262 Malapachy_1262 Malapachy_1995 Malapachy_1995 Malapachy_1093 Malapachy_1093 Malapachy_1929 Malapachy_1929 Malapachy_4022 Malapachy_4022 Malapachy_2424 Malapachy_2424 Malapachy_2149 Malapachy_2149 Malapachy_3705 Malapachy_3705 Malapachy_2214 Malapachy_2214 Malapachy_3556 Malapachy_3556 Malapachy_2758 Malapachy_2758 Malapachy_2269 Malapachy_2269 Malapachy_1544 Malapachy_1544 Malapachy_1431 Malapachy_1431 Malapachy_1578 Malapachy_1578 Malapachy_1539 Malapachy_1539 Malapachy_3133 Malapachy_3133 Malapachy_2795 Malapachy_2795 Malapachy_2836 Malapachy_2836 Malapachy_2809 Malapachy_2809 Malapachy_2525 Malapachy_2525 Malapachy_1920 Malapachy_1920 Malapachy_2002 Malapachy_2002 Malapachy_1623 Malapachy_1623 Malapachy_1871 Malapachy_1871 Malapachy_1633 Malapachy_1633 Malapachy_0224 Malapachy_0224 Malapachy_0267 Malapachy_0267 Malapachy_3348 Malapachy_3348 Malapachy_1987 Malapachy_1987 A0A0M8MU63 A0A0M8MU63 Malapachy_1138 Malapachy_1138 Malapachy_0618 Malapachy_0618 Malapachy_1760 Malapachy_1760 Malapachy_3899 Malapachy_3899 Malapachy_4192 Malapachy_4192 Malapachy_0740 Malapachy_0740 Malapachy_4147 Malapachy_4147 Malapachy_3773 Malapachy_3773 Malapachy_3900 Malapachy_3900 Malapachy_0876 Malapachy_0876 Malapachy_3968 Malapachy_3968 Malapachy_4212 Malapachy_4212 Malapachy_0673 Malapachy_0673 Malapachy_0615 Malapachy_0615 Malapachy_2119 Malapachy_2119 Malapachy_1170 Malapachy_1170 Malapachy_0926 Malapachy_0926 Malapachy_1143 Malapachy_1143 Malapachy_0967 Malapachy_0967 Malapachy_0970 Malapachy_0970 Malapachy_2573 Malapachy_2573 Malapachy_2502 Malapachy_2502 Malapachy_2218 Malapachy_2218 Malapachy_1082 Malapachy_1082 Malapachy_2683 Malapachy_2683 Malapachy_3618 Malapachy_3618 Malapachy_2426 Malapachy_2426 Malapachy_2586 Malapachy_2586 MET3 MET3 Malapachy_3021 Malapachy_3021 Malapachy_3568 Malapachy_3568 Malapachy_2161 Malapachy_2161 Malapachy_3588 Malapachy_3588 Malapachy_3490 Malapachy_3490 Malapachy_3649 Malapachy_3649 Malapachy_3502 Malapachy_3502 Malapachy_3388 Malapachy_3388 Malapachy_3580 Malapachy_3580 Malapachy_3137 Malapachy_3137 Malapachy_2808 Malapachy_2808 Malapachy_1370 Malapachy_1370 Malapachy_0434 Malapachy_0434 Malapachy_0348 Malapachy_0348 Malapachy_1332 Malapachy_1332 Malapachy_1415 Malapachy_1415 Malapachy_1584 Malapachy_1584 Malapachy_1412 Malapachy_1412 Malapachy_0091 Malapachy_0091 Malapachy_0153 Malapachy_0153 Malapachy_2039 Malapachy_2039 Malapachy_1913 Malapachy_1913 Malapachy_1701 Malapachy_1701 Malapachy_1823 Malapachy_1823 Malapachy_1862 Malapachy_1862 Malapachy_4178 Malapachy_4178 Malapachy_4080 Malapachy_4080 Malapachy_4271 Malapachy_4271 Malapachy_3955 Malapachy_3955 Malapachy_3761 Malapachy_3761 Malapachy_4210 Malapachy_4210 Malapachy_0670 Malapachy_0670 Malapachy_1128 Malapachy_1128 Malapachy_0659 Malapachy_0659 Malapachy_0959 Malapachy_0959 Malapachy_1084 Malapachy_1084 Malapachy_2416 Malapachy_2416 ALA1 ALA1 Malapachy_2479 Malapachy_2479 Malapachy_2319 Malapachy_2319 Malapachy_2471 Malapachy_2471 Malapachy_2067 Malapachy_2067 Malapachy_2372 Malapachy_2372 Malapachy_3619 Malapachy_3619 Malapachy_3198 Malapachy_3198 Malapachy_3503 Malapachy_3503 Malapachy_3617 Malapachy_3617 Malapachy_3599 Malapachy_3599 Malapachy_3280 Malapachy_3280 Malapachy_3637 Malapachy_3637 Malapachy_3030 Malapachy_3030 Malapachy_3635 Malapachy_3635 Malapachy_3627 Malapachy_3627 Malapachy_3346 Malapachy_3346 Malapachy_3564 Malapachy_3564 Malapachy_3003 Malapachy_3003 Malapachy_2823 Malapachy_2823 Malapachy_2814 Malapachy_2814 Malapachy_0317 Malapachy_0317 Malapachy_2753 Malapachy_2753 Malapachy_0049 Malapachy_0049 Malapachy_0754 Malapachy_0754 Malapachy_1272 Malapachy_1272 Malapachy_0730 Malapachy_0730 BNA1 BNA1 Malapachy_2365 Malapachy_2365
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Malapachy_3595Anthranilate synthase component 2. (770 aa)
ERG11Lanosterol 14-alpha demethylase; Belongs to the cytochrome P450 family. (540 aa)
Malapachy_0291Uncharacterized protein. (325 aa)
Malapachy_0486Histidinol-phosphatase; Belongs to the PHP hydrolase family. HisK subfamily. (367 aa)
Malapachy_1482Tyrosine--tRNA ligase. (446 aa)
Malapachy_0092Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine; Belongs to the GcvT family. (421 aa)
Malapachy_0188S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP. (385 aa)
Malapachy_1764Prolyl-trna synthetase. (717 aa)
Malapachy_4209Glutamate-trna ligase; Belongs to the class-I aminoacyl-tRNA synthetase family. (788 aa)
Malapachy_1626Pyrroline-5-carboxylate reductase; Belongs to the pyrroline-5-carboxylate reductase family. (306 aa)
Malapachy_4241Glutamyl-tRNA(Gln) amidotransferase subunit B, mitochondrial; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). Belongs to the GatB/GatE family. GatB subfamily. (553 aa)
Malapachy_0138Phosphoserine aminotransferase. (404 aa)
Malapachy_1989Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. (591 aa)
Malapachy_2793Glycine cleavage system H protein; The H protein shuttles the methylamine group of glycine from the P protein to the T protein; Belongs to the GcvH family. (163 aa)
Malapachy_4087Arg2-acetylglutamate synthase. (636 aa)
Malapachy_0524Dihydrolipoamide succinyltransferase. (441 aa)
Malapachy_2488Cysteine synthase. (374 aa)
Malapachy_3980Para-aminobenzoate synthase. (372 aa)
Malapachy_1100Glutamine-fructose-6-phosphate transaminase. (701 aa)
Malapachy_1537Chorismate synthase. (880 aa)
Malapachy_1262Uncharacterized protein. (344 aa)
Malapachy_1995Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (475 aa)
Malapachy_1093Ornithine aminotransferase. (465 aa)
Malapachy_1929Homoserine kinase. (352 aa)
Malapachy_4022Amidase signature enzyme. (424 aa)
Malapachy_2424Tyrosine--tRNA ligase. (516 aa)
Malapachy_2149Fad dependent oxidoreductase. (460 aa)
Malapachy_3705Phenylalanyl-trna synthetase. (464 aa)
Malapachy_2214Dihydroxy-acid dehydratase. (588 aa)
Malapachy_3556Glutamyl-trna synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (526 aa)
Malapachy_2758Plp-dependent transferase. (700 aa)
Malapachy_2269Tryptophanyl-trna synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (432 aa)
Malapachy_1544NAD-specific glutamate dehydrogenase; NAD(+)-dependent glutamate dehydrogenase which degrades glutamate to ammonia and alpha-ketoglutarate. Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (1043 aa)
Malapachy_1431Phenylalanyl-trna synthetase subunit beta. (605 aa)
Malapachy_1578Anthranilate phosphoribosyltransferase. (413 aa)
Malapachy_1539D-3-phosphoglycerate dehydrogenase; Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L- serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (489 aa)
Malapachy_3133Glutamate 5-kinase. (404 aa)
Malapachy_2795Saccharopine dehydrogenase [NAD(+), L-lysine-forming]; Belongs to the AlaDH/PNT family. (386 aa)
Malapachy_2836Aldo keto reductase. (515 aa)
Malapachy_2809Anthranilate synthase component. (504 aa)
Malapachy_2525Saccharopine dehydrogenase; Belongs to the spermidine/spermine synthase family. (767 aa)
Malapachy_1920Arginine biosynthesis bifunctional protein ArgJ, mitochondrial; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of acetylglutamate from glutamate and acetyl-CoA, and of ornithine by transacetylation between acetylornithine and glutamate; Belongs to the ArgJ family. (476 aa)
Malapachy_2002Aspartate aminotransferase. (421 aa)
Malapachy_16232-isopropylmalate synthase. (603 aa)
Malapachy_1871Aspartyl-trna synthetase. (568 aa)
Malapachy_1633Uncharacterized protein. (317 aa)
Malapachy_0224Threonine synthase. (521 aa)
Malapachy_0267Aspartate--trna mitochondrial. (591 aa)
Malapachy_3348Phospho-2-dehydro-3-deoxyheptonate aldolase. (365 aa)
Malapachy_1987Prephenate dehydrogenase [NADP(+)]; Belongs to the prephenate/arogenate dehydrogenase family. (453 aa)
A0A0M8MU63AA_TRNA_LIGASE_II domain-containing protein. (448 aa)
Malapachy_1138Glycyl-trna synthetase. (669 aa)
Malapachy_0618Ornithine decarboxylase; Belongs to the Orn/Lys/Arg decarboxylase class-II family. (481 aa)
Malapachy_1760Glutamate decarboxylase; Belongs to the group II decarboxylase family. (560 aa)
Malapachy_3899Aspartate mitochondrial. (427 aa)
Malapachy_4192Asparagine synthetase. (537 aa)
Malapachy_0740Asparaginyl-trna synthetase. (1022 aa)
Malapachy_4147Histidinol-phosphate aminotransferase. (409 aa)
Malapachy_3773Mitochondrial ornithine carrier protein; Belongs to the mitochondrial carrier (TC 2.A.29) family. (287 aa)
Malapachy_3900Plp-dependent transferase. (389 aa)
Malapachy_0876Uncharacterized protein. (215 aa)
Malapachy_3968Acetylornithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (476 aa)
Malapachy_4212Asparaginyl-trna synthetase. (566 aa)
Malapachy_0673Chorismate mutase. (276 aa)
Malapachy_0615Arginyl-trna synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (629 aa)
Malapachy_2119Malic enzyme. (576 aa)
Malapachy_1170Uncharacterized protein. (233 aa)
Malapachy_0926Glutamate-5-semialdehyde dehydrogenase. (487 aa)
Malapachy_1143S-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates. (317 aa)
Malapachy_0967Arg-6 mitochondrial; In the N-terminal section; belongs to the acetylglutamate kinase family. (879 aa)
Malapachy_0970Adenosylhomocysteinase. (433 aa)
Malapachy_2573Carbamoyl-phosphate synthase. (2273 aa)
Malapachy_2502Ferrichrome siderophore peptide synthetase. (3873 aa)
Malapachy_2218Aspartate-semialdehyde dehydrogenase. (366 aa)
Malapachy_1082Tryptophanyl-trna synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (397 aa)
Malapachy_2683Acetolactate synthase. (678 aa)
Malapachy_3618Vitamin b6 biosynthesis protein; Belongs to the PdxS/SNZ family. (328 aa)
Malapachy_2426Glutaminyl-trna synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (848 aa)
Malapachy_2586Atp phosphoribosyltransferase. (312 aa)
MET3Sulfate adenylyltransferase; Catalyzes the first intracellular reaction of sulfate assimilation, forming adenosine-5'-phosphosulfate (APS) from inorganic sulfate and ATP. Plays an important role in sulfate activation as a component of the biosynthesis pathway of sulfur-containing amino acids. In the N-terminal section; belongs to the sulfate adenylyltransferase family. (574 aa)
Malapachy_3021Cystathionine gamma-synthase. (434 aa)
Malapachy_35681-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase. (284 aa)
Malapachy_2161Prolyl-trna synthetase. (497 aa)
Malapachy_3588Nadph-dependent glutamate synthase. (2146 aa)
Malapachy_3490Delta-1-pyrroline-5-carboxylate dehydrogenase; Belongs to the aldehyde dehydrogenase family. (548 aa)
Malapachy_3649Carbamoyl-phosphate synthase. (1137 aa)
Malapachy_3502Arginase; Belongs to the arginase family. (319 aa)
Malapachy_3388Phenylalanyl-trna synthetase alpha chain. (538 aa)
Malapachy_3580Isoleucyl-trna synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (1034 aa)
Malapachy_3137Seryl-trna synthetase. (710 aa)
Malapachy_2808Methionyl-trna synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (551 aa)
Malapachy_13703-phosphoshikimate 1-carboxyvinyltransferase; The AROM polypeptide catalyzes 5 consecutive enzymatic reactions in prechorismate polyaromatic amino acid biosynthesis. In the 2nd section; belongs to the EPSP synthase family. In the 4th section; belongs to the type-I 3-dehydroquinase family. In the N-terminal section; belongs to the dehydroquinate synthase family. (1586 aa)
Malapachy_0434Aspartate kinase. (573 aa)
Malapachy_0348Aromatic amino acid aminotransferase. (475 aa)
Malapachy_1332Homocitrate synthase; Belongs to the alpha-IPM synthase/homocitrate synthase family. (467 aa)
Malapachy_1415Cobalamin-independent methionine synthase. (764 aa)
Malapachy_15843-isopropylmalate dehydratase; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (762 aa)
Malapachy_1412Glycine cleavage system P protein; The glycine cleavage system catalyzes the degradation of glycine. (1029 aa)
Malapachy_0091Tryptophan synthase. (698 aa)
Malapachy_0153Isocitrate dehydrogenase. (371 aa)
Malapachy_2039D-amino-acid oxidase. (373 aa)
Malapachy_1913Imidazoleglycerol-phosphate dehydratase; Belongs to the imidazoleglycerol-phosphate dehydratase family. (201 aa)
Malapachy_1701Histidyl-trna synthetase. (544 aa)
Malapachy_1823Aromatic-l-amino-acid decarboxylase. (499 aa)
Malapachy_1862CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. (605 aa)
Malapachy_4178Ketol-acid reductoisomerase, mitochondrial; Belongs to the ketol-acid reductoisomerase family. (400 aa)
Malapachy_4080Acetolactate synthase. (294 aa)
Malapachy_4271Dihydrofolate reductase; Belongs to the dihydrofolate reductase family. (280 aa)
Malapachy_39553-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. (378 aa)
Malapachy_3761Argininosuccinate synthase. (426 aa)
Malapachy_4210Homoaconitase, mitochondrial; Catalyzes the reversible hydration of cis-homoaconitate to (2R,3S)-homoisocitrate, a step in the alpha-aminoadipate pathway for lysine biosynthesis. (717 aa)
Malapachy_0670Methionyl-trna synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (711 aa)
Malapachy_1128Phospho-2-dehydro-3-deoxyheptonate aldolase. (405 aa)
Malapachy_0659Glutamine synthetase; Belongs to the glutamine synthetase family. (355 aa)
Malapachy_0959Imidazoleglycerol phosphate synthase; Belongs to the HisA/HisF family. (594 aa)
Malapachy_1084Uncharacterized protein. (195 aa)
Malapachy_2416Lysine--tRNA ligase. (577 aa)
ALA1Alanine--tRNA ligase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged tRNA(Ala) via its editing domain. Belongs to the class-II aminoacyl-tRNA synthetase family. (967 aa)
Malapachy_2479Threonine dehydratase. (575 aa)
Malapachy_2319Agmatinase; Belongs to the arginase family. (445 aa)
Malapachy_2471Leucine-trna ligase; Belongs to the class-I aminoacyl-tRNA synthetase family. (1105 aa)
Malapachy_2067Histidine biosynthesis trifunctional protein. (883 aa)
Malapachy_2372Phosphoribosylformylglycinamidine synthase. (1389 aa)
Malapachy_3619O-acetylhomoserine-lyase. (428 aa)
Malapachy_3198Cysteinyl-trna synthetase. (796 aa)
Malapachy_3503Succinate-semialdehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (498 aa)
Malapachy_3617Cystathionine beta-lyase. (841 aa)
Malapachy_3599Threonine aldolase. (382 aa)
Malapachy_3280Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. (590 aa)
Malapachy_3637Pyridoxine. (254 aa)
Malapachy_3030Ornithine carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. (363 aa)
Malapachy_3635Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (398 aa)
Malapachy_3627Bna3-arylformamidase. (462 aa)
Malapachy_3346Argininosuccinate lyase. (464 aa)
Malapachy_3564Threonyl-trna synthetase. (822 aa)
Malapachy_3003Bsp1 protein. (239 aa)
Malapachy_2823Aspartyl-trna cytoplasmic. (966 aa)
Malapachy_2814Asparagine synthase. (593 aa)
Malapachy_0317Vas1-valyl-trna synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (1053 aa)
Malapachy_2753Gmp synthase. (531 aa)
Malapachy_0049Alt1-alanine aminotransferase. (500 aa)
Malapachy_0754Bna2-tryptophan-dioxygenase. (297 aa)
Malapachy_1272Kynurenine 3-monooxygenase. (380 aa)
Malapachy_0730Cysteine synthase. (425 aa)
BNA13-hydroxyanthranilate 3,4-dioxygenase; Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate. (194 aa)
Malapachy_2365Isoleucine-trna ligase; Belongs to the class-I aminoacyl-tRNA synthetase family. (1084 aa)
Your Current Organism:
Malassezia pachydermatis
NCBI taxonomy Id: 77020
Other names: M. pachydermatis, Pityrosporum pachydermatis
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