STRINGSTRING
Malapachy_4070 Malapachy_4070 Malapachy_2787 Malapachy_2787 Malapachy_2969 Malapachy_2969 DRE2 DRE2 Malapachy_1285 Malapachy_1285 Malapachy_0978 Malapachy_0978 Malapachy_4210 Malapachy_4210 Malapachy_1986 Malapachy_1986 Malapachy_1432 Malapachy_1432 Malapachy_1625 Malapachy_1625 Malapachy_1365 Malapachy_1365 CFD1 CFD1 NBP35 NBP35 Malapachy_3588 Malapachy_3588 Malapachy_0483 Malapachy_0483 Malapachy_3300 Malapachy_3300 Malapachy_2765 Malapachy_2765 Malapachy_1017 Malapachy_1017 Malapachy_0143 Malapachy_0143 Malapachy_0861 Malapachy_0861
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
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Malapachy_4070Lipoyl synthase, mitochondrial; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. (377 aa)
Malapachy_2787Nadh dehydrogenase flavoprotein 2. (257 aa)
Malapachy_2969NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. (509 aa)
DRE2Fe-S cluster assembly protein DRE2; Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the scaffold complex CFD1-NBP35. Electrons are transferred to DRE2 from NADPH via the FAD- and FMN-containing protein TAH18. TAH18-DRE2 are also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RNR), probably by [...] (319 aa)
Malapachy_1285Aconitate hydratase, mitochondrial; Belongs to the aconitase/IPM isomerase family. (793 aa)
Malapachy_0978DNA primase large subunit; DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication; Belongs to the eukaryotic-type primase large subunit family. (509 aa)
Malapachy_4210Homoaconitase, mitochondrial; Catalyzes the reversible hydration of cis-homoaconitate to (2R,3S)-homoisocitrate, a step in the alpha-aminoadipate pathway for lysine biosynthesis. (717 aa)
Malapachy_1986DNA polymerase. (1430 aa)
Malapachy_1432Electron transfer flavoprotein-ubiquinone oxidoreductase; Accepts electrons from ETF and reduces ubiquinone. (635 aa)
Malapachy_1625Biotin synthase. (390 aa)
Malapachy_1365DNA polymerase. (1039 aa)
CFD1Cytosolic Fe-S cluster assembly factor CFD1; Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NBP35-CFD1 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins; Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP2/CFD1 subfamily. (301 aa)
NBP35Cytosolic Fe-S cluster assembly factor NBP35; Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NBP35-CFD1 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins; Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP1/NBP35 subfamily. (349 aa)
Malapachy_3588Nadph-dependent glutamate synthase. (2146 aa)
Malapachy_0483Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial; Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (289 aa)
Malapachy_3300Glutaredoxin; Belongs to the glutaredoxin family. Monothiol subfamily. (157 aa)
Malapachy_2765DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2216 aa)
Malapachy_1017DNA polymerase. (1374 aa)
Malapachy_0143Iron-sulfur cluster assembly protein; Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins. (185 aa)
Malapachy_0861Nadh-ubiquinone oxidoreductase 20 kDa subunit; Belongs to the complex I 20 kDa subunit family. (215 aa)
Your Current Organism:
Malassezia pachydermatis
NCBI taxonomy Id: 77020
Other names: M. pachydermatis, Pityrosporum pachydermatis
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