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Malapachy_0435 Malapachy_0435 Malapachy_1385 Malapachy_1385 Malapachy_0439 Malapachy_0439 Malapachy_0111 Malapachy_0111 Malapachy_1659 Malapachy_1659 Malapachy_3538 Malapachy_3538 Malapachy_1883 Malapachy_1883 Malapachy_4094 Malapachy_4094 Malapachy_3561 Malapachy_3561 Malapachy_0088 Malapachy_0088 Malapachy_3716 Malapachy_3716 Malapachy_4266 Malapachy_4266 Malapachy_1910 Malapachy_1910 Malapachy_3962 Malapachy_3962 Malapachy_4003 Malapachy_4003 PAC1 PAC1 Malapachy_1111 Malapachy_1111 Malapachy_3702 Malapachy_3702 Malapachy_3721 Malapachy_3721 Malapachy_3773 Malapachy_3773 Malapachy_1228 Malapachy_1228 Malapachy_0796 Malapachy_0796 Malapachy_2417 Malapachy_2417 Malapachy_1057 Malapachy_1057 Malapachy_2139 Malapachy_2139 Malapachy_1164 Malapachy_1164 Malapachy_0930 Malapachy_0930 Malapachy_2564 Malapachy_2564 Malapachy_1056 Malapachy_1056 Malapachy_2227 Malapachy_2227 Malapachy_2055 Malapachy_2055 Malapachy_2467 Malapachy_2467 Malapachy_3542 Malapachy_3542 Malapachy_2718 Malapachy_2718 Malapachy_3241 Malapachy_3241 Malapachy_3129 Malapachy_3129 Malapachy_3512 Malapachy_3512 Malapachy_3299 Malapachy_3299 Malapachy_1281 Malapachy_1281 Malapachy_1279 Malapachy_1279 Malapachy_2796 Malapachy_2796 Malapachy_0540 Malapachy_0540 Malapachy_0357 Malapachy_0357 Malapachy_2982 Malapachy_2982 Malapachy_0482 Malapachy_0482 Malapachy_0438 Malapachy_0438 Malapachy_1547 Malapachy_1547 Malapachy_1432 Malapachy_1432 Malapachy_1552 Malapachy_1552 Malapachy_1639 Malapachy_1639 Malapachy_0096 Malapachy_0096 Malapachy_1479 Malapachy_1479 Malapachy_0204 Malapachy_0204 Malapachy_1923 Malapachy_1923 Malapachy_3933 Malapachy_3933 Malapachy_1870 Malapachy_1870 Malapachy_4001 Malapachy_4001 Malapachy_0680 Malapachy_0680 Malapachy_1225 Malapachy_1225 Malapachy_1058 Malapachy_1058 Malapachy_1243 Malapachy_1243 Malapachy_1187 Malapachy_1187 Malapachy_2685 Malapachy_2685 Malapachy_2475 Malapachy_2475 Malapachy_2531 Malapachy_2531 Malapachy_2070 Malapachy_2070 Malapachy_4011 Malapachy_4011 Malapachy_0532 Malapachy_0532 Malapachy_0313 Malapachy_0313 Malapachy_3506 Malapachy_3506 Malapachy_4160 Malapachy_4160 Malapachy_4012 Malapachy_4012 Malapachy_4194 Malapachy_4194 Malapachy_2530 Malapachy_2530 Malapachy_0564 Malapachy_0564 Malapachy_0464 Malapachy_0464 Malapachy_0674 Malapachy_0674 Malapachy_1637 Malapachy_1637 Malapachy_1008 Malapachy_1008 Malapachy_1520 Malapachy_1520 Malapachy_2447 Malapachy_2447 Malapachy_2216 Malapachy_2216 Malapachy_0968 Malapachy_0968 Malapachy_0908 Malapachy_0908 Malapachy_2914 Malapachy_2914 Malapachy_1191 Malapachy_1191 MMM1 MMM1 Malapachy_3237 Malapachy_3237 Malapachy_3539 Malapachy_3539 Malapachy_3434 Malapachy_3434 Malapachy_3500 Malapachy_3500 Malapachy_3212 Malapachy_3212 Malapachy_3191 Malapachy_3191 Malapachy_3330 Malapachy_3330 Malapachy_2445 Malapachy_2445 Malapachy_2970 Malapachy_2970 Malapachy_3605 Malapachy_3605 Malapachy_3086 Malapachy_3086 Malapachy_0245 Malapachy_0245 Malapachy_4078 Malapachy_4078 Malapachy_4188 Malapachy_4188 Malapachy_1582 Malapachy_1582 Malapachy_1875 Malapachy_1875 EFM4 EFM4 Malapachy_0603 Malapachy_0603 Malapachy_1379 Malapachy_1379 Malapachy_2888 Malapachy_2888 Malapachy_1428 Malapachy_1428 Malapachy_0721 Malapachy_0721 Malapachy_3134 Malapachy_3134 MDM34 MDM34 Malapachy_0561 Malapachy_0561 Malapachy_0484 Malapachy_0484 Malapachy_1280 Malapachy_1280 Malapachy_0304 Malapachy_0304 Malapachy_2080 Malapachy_2080 Malapachy_1440 Malapachy_1440 Malapachy_2370 Malapachy_2370 Malapachy_2969 Malapachy_2969 Malapachy_3567 Malapachy_3567 Malapachy_3574 Malapachy_3574 Malapachy_3495 Malapachy_3495 Malapachy_3611 Malapachy_3611 Malapachy_2095 Malapachy_2095 Malapachy_2598 Malapachy_2598 Malapachy_2587 Malapachy_2587 Malapachy_2687 Malapachy_2687 Malapachy_1075 Malapachy_1075 Malapachy_1230 Malapachy_1230 Malapachy_1210 Malapachy_1210 Malapachy_3717 Malapachy_3717 Malapachy_3892 Malapachy_3892 Malapachy_1915 Malapachy_1915 Malapachy_2819 Malapachy_2819 Malapachy_3128 Malapachy_3128 Malapachy_2973 Malapachy_2973 Malapachy_3395 Malapachy_3395 GET3 GET3 Malapachy_3180 Malapachy_3180 Malapachy_3327 Malapachy_3327 Malapachy_3246 Malapachy_3246 Malapachy_2522 Malapachy_2522 Malapachy_2699 Malapachy_2699 Malapachy_2624 Malapachy_2624
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
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experimentally determined
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gene neighborhood
gene fusions
gene co-occurrence
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Malapachy_0435Nadh-ubiquinone oxidoreductase; Belongs to the complex I 49 kDa subunit family. (459 aa)
Malapachy_1385Ncs cytosine-purine permease; Belongs to the purine-cytosine permease (2.A.39) family. (512 aa)
Malapachy_0439GPI inositol-deacylase; Involved in inositol deacylation of GPI-anchored proteins which plays important roles in the quality control and ER-associated degradation of GPI-anchored proteins. (605 aa)
Malapachy_0111Dynein light chain; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in changing or maintaining the spatial distribution of cytoskeletal structures. (100 aa)
Malapachy_1659Gtp-binding protein sar1; Belongs to the small GTPase superfamily. SAR1 family. (333 aa)
Malapachy_3538General substrate transporter; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (517 aa)
Malapachy_1883Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (654 aa)
Malapachy_4094AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (169 aa)
Malapachy_3561Nuclear pore protein. (904 aa)
Malapachy_0088Eukaryotic adp atp carrier; Belongs to the mitochondrial carrier (TC 2.A.29) family. (311 aa)
Malapachy_3716Vacuolar protein sorting-associated protein 28; Component of the ESCRT-I complex (endosomal sorting complex required for transport I), a regulator of vesicular trafficking process. (224 aa)
Malapachy_4266Autophagy-related protein 3. (427 aa)
Malapachy_1910Mitochondrial carrier protein; Belongs to the mitochondrial carrier (TC 2.A.29) family. (296 aa)
Malapachy_3962Mitochondrial carrier; Belongs to the mitochondrial carrier (TC 2.A.29) family. (383 aa)
Malapachy_4003AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (143 aa)
PAC1Nuclear distribution protein PAC1; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for nuclear migration during vegetative growth as well as development. Required for retrograde early endosome (EE) transport from the hyphal tip. Required for localization of dynein to the mitotic spindle poles. Recruits additional proteins to the dynein complex at SPBs; Belongs to the WD repeat LIS1/nudF family. (433 aa)
Malapachy_1111AP-2 complex subunit alpha; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration. (962 aa)
Malapachy_3702Importin subunit alpha; Belongs to the importin alpha family. (545 aa)
Malapachy_3721Protein transport protein Sec61 subunit beta; Necessary for protein translocation in the endoplasmic reticulum. (99 aa)
Malapachy_3773Mitochondrial ornithine carrier protein; Belongs to the mitochondrial carrier (TC 2.A.29) family. (287 aa)
Malapachy_1228Mfs sugar transporter; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (630 aa)
Malapachy_0796Clathrin adaptor mu subunit; Belongs to the adaptor complexes medium subunit family. (439 aa)
Malapachy_2417Endoplasmic reticulum insertion protein sec61. (479 aa)
Malapachy_1057Sugar transporter. (587 aa)
Malapachy_2139Exportin-T; tRNA nucleus export receptor which facilitates tRNA translocation across the nuclear pore complex. Belongs to the exportin family. (1082 aa)
Malapachy_1164Adaptor protein complex ap-3 delta subunit. (802 aa)
Malapachy_0930Vacuolar atp synthase proteolipid subunit; Belongs to the V-ATPase proteolipid subunit family. (203 aa)
Malapachy_2564Cysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy. (716 aa)
Malapachy_1056Sugar transporter. (591 aa)
Malapachy_2227Cytochrome c; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (124 aa)
Malapachy_205560S ribosomal export protein NMD3; Acts as an adapter for the XPO1/CRM1-mediated export of the 60S ribosomal subunit; Belongs to the NMD3 family. (554 aa)
Malapachy_2467Trafficking protein particle complex subunit; Belongs to the TRAPP small subunits family. (247 aa)
Malapachy_3542AP-1 complex subunit gamma. (832 aa)
Malapachy_2718Beta3 protein. (798 aa)
Malapachy_3241Protein transport protein sec24c. (1219 aa)
Malapachy_3129Mitochondrial carrier; Belongs to the mitochondrial carrier (TC 2.A.29) family. (321 aa)
Malapachy_3512Mitochondrial import inner membrane translocase subunit TIM50; Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane. (488 aa)
Malapachy_3299Golgi SNAP receptor complex member 1; Involved in transport from the ER to the Golgi apparatus as well as in intra-Golgi transport. It belongs to a super-family of proteins called t-SNAREs or soluble NSF (N-ethylmaleimide-sensitive factor) attachment protein receptor. (248 aa)
Malapachy_1281Cytochrome c oxidase subunit 1; Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B. (152 aa)
Malapachy_1279NADH-ubiquinone oxidoreductase chain 5; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (747 aa)
Malapachy_2796Mrs11-subunit of the tim22-complex. (99 aa)
Malapachy_0540General substrate transporter; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (613 aa)
Malapachy_0357Sulfate permease. (851 aa)
Malapachy_2982Exocyst complex component SEC5; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. Belongs to the SEC5 family. (844 aa)
Malapachy_0482Carnitine acyl carnitine carrier; Belongs to the mitochondrial carrier (TC 2.A.29) family. (308 aa)
Malapachy_0438Mitochondrial carrier; Belongs to the mitochondrial carrier (TC 2.A.29) family. (719 aa)
Malapachy_1547Mitochondrial carrier; Belongs to the mitochondrial carrier (TC 2.A.29) family. (271 aa)
Malapachy_1432Electron transfer flavoprotein-ubiquinone oxidoreductase; Accepts electrons from ETF and reduces ubiquinone. (635 aa)
Malapachy_1552Nuclear pore complex protein Nup85; Functions as a component of the nuclear pore complex (NPC). (698 aa)
Malapachy_1639Mitochondrial carrier; Belongs to the mitochondrial carrier (TC 2.A.29) family. (533 aa)
Malapachy_0096V-type proton ATPase subunit G; Catalytic subunit of the peripheral V1 complex of vacuolar ATPase (V-ATPase). V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (120 aa)
Malapachy_1479Wd40 repeat-like protein; Belongs to the WD repeat SEC13 family. (349 aa)
Malapachy_0204Tim9-translocase of the mitochondrial inner membrane. (89 aa)
Malapachy_1923Zip-like iron-zinc transporter. (359 aa)
Malapachy_3933Coatomer subunit epsilon; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. The coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. Belongs to the COPE family. (312 aa)
Malapachy_1870Coatomer subunit gamma; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. (921 aa)
Malapachy_4001Mitochondrial carrier; Belongs to the mitochondrial carrier (TC 2.A.29) family. (336 aa)
Malapachy_0680Guided entry of tail-anchored protein. (232 aa)
Malapachy_1225Uaa transporter. (357 aa)
Malapachy_1058Sugar transporter. (570 aa)
Malapachy_1243Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (639 aa)
Malapachy_1187Sortilin; Functions as a sorting receptor in the Golgi compartment required for the intracellular sorting and delivery of soluble vacuolar proteins, like carboxypeptidase Y (CPY) and proteinase A. (1475 aa)
Malapachy_2685Clathrin adaptor mu subunit; Belongs to the adaptor complexes medium subunit family. (420 aa)
Malapachy_2475Glutaredoxin-like protein; Belongs to the glutaredoxin family. (105 aa)
Malapachy_2531Ammonium transporter. (504 aa)
Malapachy_2070Mitochondrial carrier; Belongs to the mitochondrial carrier (TC 2.A.29) family. (310 aa)
Malapachy_4011Udp-galactose transporter. (415 aa)
Malapachy_0532Vacuolar proton pump subunit B; Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase; Belongs to the ATPase alpha/beta chains family. (514 aa)
Malapachy_0313Nucleoside; Belongs to the purine-cytosine permease (2.A.39) family. (518 aa)
Malapachy_3506Trafficking protein particle complex subunit; Belongs to the TRAPP small subunits family. (140 aa)
Malapachy_4160Potassium transport protein; Belongs to the TrkH potassium transport family. (946 aa)
Malapachy_4012S-adenosylmethionine transporter; Belongs to the mitochondrial carrier (TC 2.A.29) family. (293 aa)
Malapachy_4194V-type proton ATPase subunit C; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (397 aa)
Malapachy_2530Vacuolar calcium ion transporter; Has a role in promoting intracellular calcium ion sequestration via the exchange of calcium ions for hydrogen ions across the vacuolar membrane. Involved also in manganese ion homeostasis via its uptake into the vacuole; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (416 aa)
Malapachy_0564Nadh-ubiquinone oxidoreductase; Belongs to the complex I 30 kDa subunit family. (280 aa)
Malapachy_0464Protein transport protein SEC23; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules; Belongs to the SEC23/SEC24 family. SEC23 subfamily. (761 aa)
Malapachy_0674Chloride channel protein. (894 aa)
Malapachy_1637V-type proton ATPase subunit F; Subunit of the peripheral V1 complex of vacuolar ATPase essential for assembly or catalytic function. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (121 aa)
Malapachy_1008Nuclear pore complex protein; Functions as a component of the nuclear pore complex (NPC). (772 aa)
Malapachy_1520Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1253 aa)
Malapachy_2447Mitochondrial pyruvate carrier; Mediates the uptake of pyruvate into mitochondria. Belongs to the mitochondrial pyruvate carrier (MPC) (TC 2.A.105) family. (124 aa)
Malapachy_2216V-type proton ATPase subunit; Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. The active enzyme consists of a catalytic V1 domain attached to an integral membrane V0 proton pore complex. This subunit is a non-integral membrane component of the membrane pore domain and is required for proper assembly of the V0 sector. Might be involved in the regulated assembly of V1 subunits onto the membrane sector or alternatively may prevent the passage of protons through V0 pores; Belongs to the V-ATPase V0D/AC39 subunit family. (354 aa)
Malapachy_0968Mitochondrial carrier; Belongs to the mitochondrial carrier (TC 2.A.29) family. (336 aa)
Malapachy_0908Mitochondrial distribution and morphology protein 12. (288 aa)
Malapachy_2914Acyl-CoA desaturase; Stearyl-CoA desaturase that utilizes O(2) and electrons from reduced cytochrome b5 to introduce the first double bond into saturated fatty acyl-CoA substrates. (527 aa)
Malapachy_1191ATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane. (547 aa)
MMM1Maintenance of mitochondrial morphology protein 1; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. The MDM12-MMM1 subcomplex functions in the major beta-barrel assembly pathway that is responsible for biogenesis of all outer membrane beta- barrel proteins, and acts in a late step after the SAM complex. The MDM10-MDM12-MMM1 su [...] (335 aa)
Malapachy_3237Plasma membrane ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIIA subfamily. (1064 aa)
Malapachy_3539Exocyst complex component SEC15; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. (785 aa)
Malapachy_3434Mitochondrial tricarboxylate transporter; Belongs to the mitochondrial carrier (TC 2.A.29) family. (302 aa)
Malapachy_3500Mfs sugar transporter; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (668 aa)
Malapachy_3212Mitochondrial pyruvate carrier; Mediates the uptake of pyruvate into mitochondria. Belongs to the mitochondrial pyruvate carrier (MPC) (TC 2.A.105) family. (121 aa)
Malapachy_3191Mitochondrial import inner membrane translocase subunit tim8; Belongs to the small Tim family. (84 aa)
Malapachy_3330AP complex subunit beta; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration. (713 aa)
Malapachy_2445Phosphate transport protein mir1; Belongs to the mitochondrial carrier (TC 2.A.29) family. (326 aa)
Malapachy_2970Ca2+-dependent lipid-binding protein clb1. (1104 aa)
Malapachy_3605Sugar transporter. (451 aa)
Malapachy_3086Mitochondrial fad carrier protein; Belongs to the mitochondrial carrier (TC 2.A.29) family. (386 aa)
Malapachy_0245Ap-3 adapter complex mu3a subunit; Belongs to the adaptor complexes medium subunit family. (564 aa)
Malapachy_4078Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 and ATG8 for its conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Autophagy is essential for maintenance of amino acid levels and protein synthesis under nitrogen starvation. Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy wh [...] (688 aa)
Malapachy_4188Succinate:fumarate antiporter; Belongs to the mitochondrial carrier (TC 2.A.29) family. (318 aa)
Malapachy_1582V-type proton ATPase proteolipid subunit; Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (182 aa)
Malapachy_1875Sugar transporter stl1; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (598 aa)
EFM4Protein-lysine N-methyltransferase EFM4; S-adenosyl-L-methionine-dependent protein-lysine N- methyltransferase that mono- and dimethylates elongation factor 1-alpha at 'Lys-316'. May play a role in intracellular transport. Belongs to the class I-like SAM-binding methyltransferase superfamily. EFM4 family. (254 aa)
Malapachy_0603Mitochondrial glycine transporter; Mitochondrial glycine transporter that imports glycine into the mitochondrial matrix. Plays an important role in providing glycine for the first enzymatic step in heme biosynthesis, the condensation of glycine with succinyl-CoA to produce 5-aminolevulinate (ALA) in the miochondrial matrix; Belongs to the mitochondrial carrier (TC 2.A.29) family. SLC25A38 subfamily. (321 aa)
Malapachy_1379Protein transport protein sec16; Involved in the initiation of assembly of the COPII coat required for the formation of transport vesicles from the endoplasmic reticulum (ER) and the selection of cargo molecules. Also involved in autophagy; Belongs to the SEC16 family. (2029 aa)
Malapachy_2888Pleiotropic drug resistance abc transporter; Belongs to the ABC transporter superfamily. ABCG family. PDR (TC 3.A.1.205) subfamily. (3120 aa)
Malapachy_1428Coatomer subunit delta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. (653 aa)
Malapachy_0721Vesicle-mediated transport-related protein. (346 aa)
Malapachy_3134Mitochondrial carrier; Belongs to the mitochondrial carrier (TC 2.A.29) family. (363 aa)
MDM34Mitochondrial distribution and morphology protein 34; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. MDM34 is required for the interaction of the ER-resident membrane protein MMM1 and the outer mitochondrial membrane-resident beta-barrel protein MDM10. (379 aa)
Malapachy_0561Dicarboxylic acid transporter; Belongs to the mitochondrial carrier (TC 2.A.29) family. (322 aa)
Malapachy_0484Mitochondrial nad transporter; Belongs to the mitochondrial carrier (TC 2.A.29) family. (166 aa)
Malapachy_1280Cytochrome c oxidase subunit 2; Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. Subunit 2 transfers the electrons from cytochrome c via its binuclear copper A center to the bimetallic center of the catalytic subunit 1. (536 aa)
Malapachy_0304Conserved oligomeric Golgi complex subunit 6; Acts as component of the peripheral membrane COG complex that is involved in intra-Golgi protein trafficking. COG is located at the cis-Golgi, and regulates tethering of retrograde intra-Golgi vesicles and possibly a number of other membrane trafficking events. (688 aa)
Malapachy_2080Gtp-binding protein. (360 aa)
Malapachy_1440Exocyst complex protein EXO70; Involved in the secretory pathway as part of the exocyst complex which tethers secretory vesicles to the sites of exocytosis. Also plays a role in the assembly of the exocyst. Belongs to the EXO70 family. (633 aa)
Malapachy_2370ATP synthase subunit gamma. (305 aa)
Malapachy_2969NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. (509 aa)
Malapachy_3567Trafficking protein particle complex subunit; Belongs to the TRAPP small subunits family. BET3 subfamily. (233 aa)
Malapachy_3574V-type proton ATPase subunit H; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit H activates ATPase activity of the enzyme and couples ATPase activity to proton flow. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. (490 aa)
Malapachy_3495NADH-ubiquinone oxidoreductase; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (155 aa)
Malapachy_3611Mitochondrial carrier family protein; Belongs to the mitochondrial carrier (TC 2.A.29) family. (411 aa)
Malapachy_2095Probable vacuolar protein sorting-associated protein 16 homolog; Essential for vacuolar protein sorting. Required for vacuole biogenesis, stability and to maintain vacuole morphology. (881 aa)
Malapachy_2598Ant1-peroxisomal atp carrier; Belongs to the mitochondrial carrier (TC 2.A.29) family. (307 aa)
Malapachy_2587Tim13-translocase of the inner membrane; Belongs to the small Tim family. (99 aa)
Malapachy_2687Protein transporter sec24. (1100 aa)
Malapachy_1075GTP-binding nuclear protein; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle. Belongs to the small GTPase superfamily. Ran family. (216 aa)
Malapachy_1230Vacuole protein. (900 aa)
Malapachy_1210RRM Nup35-type domain-containing protein. (547 aa)
Malapachy_3717Tcb3-protein localized to bud-enriched. (1415 aa)
Malapachy_3892Mitochondrial carrier; Belongs to the mitochondrial carrier (TC 2.A.29) family. (294 aa)
Malapachy_1915Mitochondrial import inner membrane translocase subunit TIM44; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner; Belongs to the Tim44 family. (489 aa)
Malapachy_2819V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (842 aa)
Malapachy_3128Protein SDA1; Required for 60S pre-ribosomal subunits export to the cytoplasm; Belongs to the SDA1 family. (837 aa)
Malapachy_2973Yhm2-protein of the mitochondrial carrier family; Belongs to the mitochondrial carrier (TC 2.A.29) family. (298 aa)
Malapachy_3395Mitochondrial carrier; Belongs to the mitochondrial carrier (TC 2.A.29) family. (300 aa)
GET3ATPase GET3; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. S [...] (330 aa)
Malapachy_3180Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (989 aa)
Malapachy_3327Vacuolar protein sorting-associated protein 35; Plays a role in vesicular protein sorting. (997 aa)
Malapachy_3246Mitochondrial carrier; Belongs to the mitochondrial carrier (TC 2.A.29) family. (330 aa)
Malapachy_2522Mitochondrial carrier; Belongs to the mitochondrial carrier (TC 2.A.29) family. (435 aa)
Malapachy_2699Coatomer subunit beta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. (956 aa)
Malapachy_2624Coatomer subunit beta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. (810 aa)
Your Current Organism:
Malassezia pachydermatis
NCBI taxonomy Id: 77020
Other names: M. pachydermatis, Pityrosporum pachydermatis
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