39 items (Malassezia pachydermatis) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Malapachy_0291	Uncharacterized protein. (325 aa)
	Malapachy_1474	L-serine dehydratase. (657 aa)
	Malapachy_0188	S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP. (385 aa)
	Malapachy_0138	Phosphoserine aminotransferase. (404 aa)
	Malapachy_2897	Uncharacterized protein. (1283 aa)
	Malapachy_2488	Cysteine synthase. (374 aa)
	Malapachy_3467	Prefoldin subunit 3; Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins; Belongs to the prefoldin subunit alpha family. (177 aa)
	Malapachy_2758	Plp-dependent transferase. (700 aa)
	Malapachy_2287	Uncharacterized protein. (306 aa)
	Malapachy_1539	D-3-phosphoglycerate dehydrogenase; Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L- serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (489 aa)
	Malapachy_2525	Saccharopine dehydrogenase; Belongs to the spermidine/spermine synthase family. (767 aa)
	Malapachy_3276	rRNA adenine N(6)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. (445 aa)
	Malapachy_2002	Aspartate aminotransferase. (421 aa)
	Malapachy_1606	Hnh endonuclease family protein. (119 aa)
	Malapachy_1633	Uncharacterized protein. (317 aa)
	Malapachy_0146	Uncharacterized protein. (251 aa)
	Malapachy_3899	Aspartate mitochondrial. (427 aa)
	Malapachy_1143	S-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates. (317 aa)
	Malapachy_0970	Adenosylhomocysteinase. (433 aa)
	Malapachy_2218	Aspartate-semialdehyde dehydrogenase. (366 aa)
	Malapachy_3021	Cystathionine gamma-synthase. (434 aa)
	Malapachy_3291	Nad-malate dehydrogenase; Belongs to the LDH/MDH superfamily. (330 aa)
	Malapachy_3337	rRNA adenine N(6)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. (325 aa)
	Malapachy_2979	Glutathione synthetase. (521 aa)
	Malapachy_2762	S-adenosylmethionine decarboxylase proenzyme. (436 aa)
	Malapachy_0365	Homoserine o-acetyltransferase. (467 aa)
	Malapachy_0434	Aspartate kinase. (573 aa)
	Malapachy_1415	Cobalamin-independent methionine synthase. (764 aa)
	Malapachy_1710	Uncharacterized protein. (224 aa)
	Malapachy_4077	Uncharacterized protein. (255 aa)
	Malapachy_1084	Uncharacterized protein. (195 aa)
	Malapachy_2056	Glutamate-cysteine ligase catalytic subunit. (662 aa)
	Malapachy_2108	Malate dehydrogenase; Belongs to the LDH/MDH superfamily. (346 aa)
	Malapachy_3619	O-acetylhomoserine-lyase. (428 aa)
	Malapachy_3617	Cystathionine beta-lyase. (841 aa)
	Malapachy_3635	Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (398 aa)
	Malapachy_3018	Uncharacterized protein. (263 aa)
	Malapachy_0730	Cysteine synthase. (425 aa)
	Malapachy_0874	Rhodanese domain-containing protein. (186 aa)

Your Current Organism:

Malassezia pachydermatis

NCBI taxonomy Id: 77020
Other names: M. pachydermatis, Pityrosporum pachydermatis

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Malapachy_0138	Malapachy_0188	A0A0M8MKL6	A0A0M8MIY8	Phosphoserine aminotransferase.	S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP.	0.453
Malapachy_0138	Malapachy_0434	A0A0M8MKL6	A0A0M9VN14	Phosphoserine aminotransferase.	Aspartate kinase.	0.566
Malapachy_0138	Malapachy_0730	A0A0M8MKL6	A0A0N0RSE7	Phosphoserine aminotransferase.	Cysteine synthase.	0.951
Malapachy_0138	Malapachy_1539	A0A0M8MKL6	A0A0M8MS10	Phosphoserine aminotransferase.	D-3-phosphoglycerate dehydrogenase; Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L- serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	0.998
Malapachy_0138	Malapachy_2002	A0A0M8MKL6	A0A0M8MSW6	Phosphoserine aminotransferase.	Aspartate aminotransferase.	0.471
Malapachy_0138	Malapachy_2218	A0A0M8MKL6	A0A0M8MWH4	Phosphoserine aminotransferase.	Aspartate-semialdehyde dehydrogenase.	0.657
Malapachy_0138	Malapachy_2488	A0A0M8MKL6	A0A0M8MM69	Phosphoserine aminotransferase.	Cysteine synthase.	0.951
Malapachy_0138	Malapachy_3899	A0A0M8MKL6	A0A0M8MUI9	Phosphoserine aminotransferase.	Aspartate mitochondrial.	0.498
Malapachy_0188	Malapachy_0138	A0A0M8MIY8	A0A0M8MKL6	S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP.	Phosphoserine aminotransferase.	0.453
Malapachy_0188	Malapachy_0434	A0A0M8MIY8	A0A0M9VN14	S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP.	Aspartate kinase.	0.616
Malapachy_0188	Malapachy_0730	A0A0M8MIY8	A0A0N0RSE7	S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP.	Cysteine synthase.	0.594
Malapachy_0188	Malapachy_0970	A0A0M8MIY8	A0A0M8MWB8	S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP.	Adenosylhomocysteinase.	0.867
Malapachy_0188	Malapachy_1143	A0A0M8MIY8	A0A0M8MW80	S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP.	S-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.	0.523
Malapachy_0188	Malapachy_1415	A0A0M8MIY8	A0A0M9VN71	S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP.	Cobalamin-independent methionine synthase.	0.990
Malapachy_0188	Malapachy_1539	A0A0M8MIY8	A0A0M8MS10	S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP.	D-3-phosphoglycerate dehydrogenase; Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L- serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	0.419
Malapachy_0188	Malapachy_1633	A0A0M8MIY8	A0A0M8MTA3	S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP.	Uncharacterized protein.	0.661
Malapachy_0188	Malapachy_2002	A0A0M8MIY8	A0A0M8MSW6	S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP.	Aspartate aminotransferase.	0.679
Malapachy_0188	Malapachy_2218	A0A0M8MIY8	A0A0M8MWH4	S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP.	Aspartate-semialdehyde dehydrogenase.	0.564
Malapachy_0188	Malapachy_2488	A0A0M8MIY8	A0A0M8MM69	S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP.	Cysteine synthase.	0.594
Malapachy_0188	Malapachy_2758	A0A0M8MIY8	A0A0M8MQT4	S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP.	Plp-dependent transferase.	0.539