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Malapachy_3077 Malapachy_3077 Malapachy_1296 Malapachy_1296 Malapachy_1828 Malapachy_1828 Malapachy_0557 Malapachy_0557 Malapachy_1644 Malapachy_1644 TIF6 TIF6 Malapachy_0156 Malapachy_0156 Malapachy_1014 Malapachy_1014 Malapachy_2274 Malapachy_2274 Malapachy_2476 Malapachy_2476 Malapachy_2407 Malapachy_2407 Malapachy_2186 Malapachy_2186 Malapachy_0856 Malapachy_0856 Malapachy_1249 Malapachy_1249 Malapachy_1829 Malapachy_1829 Malapachy_2601 Malapachy_2601 Malapachy_3123 Malapachy_3123 Malapachy_3154 Malapachy_3154 Malapachy_0635 Malapachy_0635 Malapachy_2537 Malapachy_2537 Malapachy_2802 Malapachy_2802 Malapachy_3501 Malapachy_3501 Malapachy_1842 Malapachy_1842 Malapachy_1562 Malapachy_1562 Malapachy_1612 Malapachy_1612 Malapachy_2985 Malapachy_2985 Malapachy_0178 Malapachy_0178 Malapachy_4274 Malapachy_4274 Malapachy_4239 Malapachy_4239 Malapachy_2224 Malapachy_2224 Malapachy_0885 Malapachy_0885 Malapachy_0770 Malapachy_0770 Malapachy_2171 Malapachy_2171 Malapachy_2672 Malapachy_2672 Malapachy_2055 Malapachy_2055 Malapachy_2735 Malapachy_2735 Malapachy_2178 Malapachy_2178 Malapachy_3531 Malapachy_3531 Malapachy_3620 Malapachy_3620 Malapachy_3090 Malapachy_3090 Malapachy_3358 Malapachy_3358 Malapachy_0361 Malapachy_0361 Malapachy_0398 Malapachy_0398 NAT10 NAT10 Malapachy_1574 Malapachy_1574 Malapachy_0007 Malapachy_0007 Malapachy_3785 Malapachy_3785 Malapachy_3894 Malapachy_3894 Malapachy_3703 Malapachy_3703 Malapachy_4137 Malapachy_4137 Malapachy_1123 Malapachy_1123 Malapachy_1005 Malapachy_1005 Malapachy_1176 Malapachy_1176 Malapachy_0628 Malapachy_0628 Malapachy_0777 Malapachy_0777 Malapachy_0771 Malapachy_0771 Malapachy_1094 Malapachy_1094 Malapachy_2260 Malapachy_2260 Malapachy_2158 Malapachy_2158 Malapachy_2508 Malapachy_2508 Malapachy_3070 Malapachy_3070 Malapachy_3508 Malapachy_3508 Malapachy_3183 Malapachy_3183 Malapachy_3278 Malapachy_3278 Malapachy_2907 Malapachy_2907 Malapachy_3232 Malapachy_3232 Malapachy_3167 Malapachy_3167 Malapachy_3589 Malapachy_3589 Malapachy_0724 Malapachy_0724 Malapachy_1075 Malapachy_1075 Malapachy_2640 Malapachy_2640
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Malapachy_3077Emg1-protein required for ribosome biogenesis. (385 aa)
Malapachy_12965'-3' exoribonuclease 1; Multifunctional protein that exhibits several independent functions at different levels of the cellular processes. 5'-3' exonuclease component of the nonsense-mediated mRNA decay (NMD) which is a highly conserved mRNA degradation pathway, an RNA surveillance system whose role is to identify and rid cells of mRNA with premature termination codons and thus prevents accumulation of potentially harmful truncated proteins. (1392 aa)
Malapachy_1828Pseudouridine synthase. (367 aa)
Malapachy_0557Brix-domain-containing protein. (295 aa)
Malapachy_1644Fcf1-domain-containing protein. (194 aa)
TIF6Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. Is also involved in ribosome biogenesis. Associates with pre-60S subunits in the nucleus and is involved in its nuclear export; Belongs to the eIF-6 family. (245 aa)
Malapachy_0156Casein kinase-1 hhp1; Belongs to the protein kinase superfamily. (397 aa)
Malapachy_1014Uncharacterized protein. (230 aa)
Malapachy_2274Protein kinase ck2 alpha subunit; Belongs to the protein kinase superfamily. (336 aa)
Malapachy_2476P-loop containing nucleoside triphosphate hydrolase protein. (558 aa)
Malapachy_2407Uncharacterized protein. (416 aa)
Malapachy_2186Fcf2 domain-containing protein. (258 aa)
Malapachy_0856Nop domain-containing protein. (534 aa)
Malapachy_1249Shwachman-bodian-diamond syndrome protein. (245 aa)
Malapachy_1829Rrna pseudouridine synthase. (489 aa)
Malapachy_2601Myosin i binding protein. (1077 aa)
Malapachy_3123Serine threonine protein kinase. (242 aa)
Malapachy_3154Wd40 repeat-like protein. (820 aa)
Malapachy_0635U3 small nucleolar rna-associated protein 10. (2057 aa)
Malapachy_2537Utp13-u3 snornp protein. (921 aa)
Malapachy_2802Uncharacterized protein. (506 aa)
Malapachy_3501Nucleolar GTP-binding protein 1; Involved in the biogenesis of the 60S ribosomal subunit. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. NOG subfamily. (702 aa)
Malapachy_1842Nuc189-domain-containing protein. (776 aa)
Malapachy_1562Rna-binding domain-containing protein. (885 aa)
Malapachy_1612Wd40 repeat-like protein. (557 aa)
Malapachy_2985Ntf2-like protein. (205 aa)
Malapachy_0178Utp14-domain-containing protein. (831 aa)
Malapachy_4274Rnase p protein subunit. (238 aa)
Malapachy_4239Kri1_C domain-containing protein. (566 aa)
Malapachy_2224Ribosome biogenesis protein bms1. (1001 aa)
Malapachy_0885Ntf2-like protein. (602 aa)
Malapachy_0770Utp21-domain-containing protein. (955 aa)
Malapachy_2171Casein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family. (313 aa)
Malapachy_267220S-pre-rRNA D-site endonuclease NOB1; Required for the synthesis of 40S ribosome subunits. Has a role in processing 20S pre-rRNA into the mature 18S rRNA, where it is required for cleavage at the 3' end of the mature 18S rRNA (D-site). Accompanies the 20S pre-rRNA from the nucleus to the cytoplasm. Belongs to the NOB1 family. (454 aa)
Malapachy_205560S ribosomal export protein NMD3; Acts as an adapter for the XPO1/CRM1-mediated export of the 60S ribosomal subunit; Belongs to the NMD3 family. (554 aa)
Malapachy_2735U3 small nucleolar RNA-associated protein 22. (1212 aa)
Malapachy_2178Pop1-domain-containing protein. (838 aa)
Malapachy_3531Rrna processing protein rrp7. (355 aa)
Malapachy_362018s rrna biogenesis protein. (368 aa)
Malapachy_30905'-3' exoribonuclease; Possesses 5'->3' exoribonuclease activity. May promote termination of transcription by RNA polymerase II. (1096 aa)
Malapachy_3358Cytoplasmic protein. (442 aa)
Malapachy_0361Rexo1 protein. (537 aa)
Malapachy_0398Bromodomain-containing protein. (744 aa)
NAT10RNA cytidine acetyltransferase; RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires the tRNA- binding adapter protein TAN1 for full tRNA acetyltransferase activity but not for 18S rRNA acetylation. (1052 aa)
Malapachy_1574Wd-repeat-containing protein. (944 aa)
Malapachy_0007Mpp10 protein. (789 aa)
Malapachy_3785P-loop containing nucleoside triphosphate hydrolase protein. (670 aa)
Malapachy_3894Adenylate kinase isoenzyme 6 homolog; Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. Has also ATPase activity. May be involved in rRNA maturation and transcription regulation. (208 aa)
Malapachy_3703Serine threonine-protein kinase rio2. (530 aa)
Malapachy_4137Ribonuclease h-like protein. (207 aa)
Malapachy_1123H aca ribonucleoprotein complex subunit 3. (62 aa)
Malapachy_1005U3 snornp protein. (1018 aa)
Malapachy_1176Peroxisome biosynthesis protein pas1 (Peroxin-1). (747 aa)
Malapachy_0628Nucleolar GTP-binding protein 2; GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation. Belongs to the TRAFAC class YlqF/YawG GTPase family. NOG2 subfamily. (676 aa)
Malapachy_0777Midasin; Nuclear chaperone required for maturation and nuclear export of pre-60S ribosome subunits; Belongs to the midasin family. (4873 aa)
Malapachy_0771Wd repeat. (868 aa)
Malapachy_1094Rna-binding protein nhp2. (201 aa)
Malapachy_2260Nop1-fibrillarin. (315 aa)
Malapachy_2158Rio1-domain-containing protein. (651 aa)
Malapachy_2508GN3L_Grn1 domain-containing protein. (608 aa)
Malapachy_3070Alpha-l rna-binding motif-containing protein. (182 aa)
Malapachy_3508Ribosome biogenesis atpase rix7. (738 aa)
Malapachy_3183Casein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family. (297 aa)
Malapachy_3278Crm1-nuclear export exportin. (1081 aa)
Malapachy_2907Ribonucloprotein; Common component of the spliceosome and rRNA processing machinery; Belongs to the eukaryotic ribosomal protein eL8 family. (128 aa)
Malapachy_3232Uncharacterized protein. (207 aa)
Malapachy_3167Wd40 repeat-like protein. (838 aa)
Malapachy_3589Nop-domain-containing protein. (518 aa)
Malapachy_0724Wd40 repeat-like protein. (554 aa)
Malapachy_1075GTP-binding nuclear protein; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle. Belongs to the small GTPase superfamily. Ran family. (216 aa)
Malapachy_2640Translation elongation factor 2. (1059 aa)
Your Current Organism:
Malassezia pachydermatis
NCBI taxonomy Id: 77020
Other names: M. pachydermatis, Pityrosporum pachydermatis
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