42 items (Dendroctonus ponderosae) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	D910_08742	Uncharacterized protein. (212 aa)
	D910_05695	BRO1 domain-containing protein. (824 aa)
	D910_09371	Uncharacterized protein. (223 aa)
	D910_10140	Uncharacterized protein. (206 aa)
	D910_07890	Vacuolar-sorting protein SNF8; Component of the endosomal sorting complex required for transport II (ESCRT-II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs. Belongs to the SNF8 family. (252 aa)
	D910_03638	Uncharacterized protein. (220 aa)
	D910_03047	GLUE N-terminal domain-containing protein. (391 aa)
	D910_11536	Uncharacterized protein. (466 aa)
	D910_04487	Uncharacterized protein. (153 aa)
	D910_12202	Uncharacterized protein. (288 aa)
	D910_00332	Uncharacterized protein. (219 aa)
	D910_03335	AAA domain-containing protein; Belongs to the AAA ATPase family. (547 aa)
	D910_05303	Uncharacterized protein. (391 aa)
	D910_11633	Uncharacterized protein; Belongs to the AAA ATPase family. (437 aa)
	D910_10857	Uncharacterized protein. (1669 aa)
	D910_06141	Uncharacterized protein; Belongs to the VPS28 family. (214 aa)
	D910_02124	Uncharacterized protein. (212 aa)
	D910_02044	Uncharacterized protein; Belongs to the peptidase C2 family. (978 aa)
	D910_05355	Uncharacterized protein. (505 aa)
	D910_03166	USP domain-containing protein; Belongs to the peptidase C19 family. (241 aa)
	D910_04939	BRO1 domain-containing protein. (204 aa)
	D910_06730	Uncharacterized protein. (693 aa)
	D910_08125	Uncharacterized protein. (712 aa)
	D910_05279	Myb_DNA-bind_5 domain-containing protein. (119 aa)
	D910_07041	Uncharacterized protein. (197 aa)
	D910_07084	Calpain catalytic domain-containing protein; Belongs to the peptidase C2 family. (480 aa)
	D910_05390	Uncharacterized protein. (250 aa)
	D910_04877	Calpain_III domain-containing protein. (173 aa)
	D910_08261	Uncharacterized protein. (177 aa)
	D910_09773	Uncharacterized protein. (412 aa)
	D910_06590	Hepatocyte growth factor-regulated tyrosine kinase substrate; Essential role in endosome membrane invagination and formation of multivesicular bodies, MVBs. Required during gastrulation and appears to regulate early embryonic signaling pathways. Inhibits tyrosine kinase receptor signaling by promoting degradation of the tyrosine-phosphorylated, active receptor, potentially by sorting activated receptors into MVBs. The MVBs are then trafficked to the lysosome where their contents are degraded. (659 aa)
	D910_09976	Uncharacterized protein; Belongs to the AAA ATPase family. (180 aa)
	D910_10401	Uncharacterized protein. (535 aa)
	D910_08863	Uncharacterized protein. (347 aa)
	D910_09870	VPS37 C-terminal domain-containing protein. (236 aa)
	D910_10100	Uncharacterized protein. (365 aa)
	D910_11125	Uncharacterized protein. (227 aa)
	D910_11225	Uncharacterized protein. (177 aa)
	D910_11224	Uncharacterized protein. (173 aa)
	D910_12071	Uncharacterized protein. (184 aa)
	D910_09977	ATPase_AAA_core domain-containing protein. (226 aa)
	D910_11162	Uncharacterized protein. (427 aa)

Your Current Organism:

Dendroctonus ponderosae

NCBI taxonomy Id: 77166
Other names: D. ponderosae, mountain pine beetle

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structured XML interaction data, according to the 'PSI-MI' data standard

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
D910_00332	D910_02124	N6TGA5	U4TT48	Uncharacterized protein.	Uncharacterized protein.	0.987
D910_00332	D910_03047	N6TGA5	J3JYD3	Uncharacterized protein.	GLUE N-terminal domain-containing protein.	0.896
D910_00332	D910_03166	N6TGA5	U4U577	Uncharacterized protein.	USP domain-containing protein; Belongs to the peptidase C19 family.	0.595
D910_00332	D910_03335	N6TGA5	N6TJE9	Uncharacterized protein.	AAA domain-containing protein; Belongs to the AAA ATPase family.	0.788
D910_00332	D910_03638	N6TGA5	J3JXU3	Uncharacterized protein.	Uncharacterized protein.	0.997
D910_00332	D910_05303	N6TGA5	N6TTI4	Uncharacterized protein.	Uncharacterized protein.	0.898
D910_00332	D910_05355	N6TGA5	U4U4I4	Uncharacterized protein.	Uncharacterized protein.	0.663
D910_00332	D910_05390	N6TGA5	U4UBM3	Uncharacterized protein.	Uncharacterized protein.	0.997
D910_00332	D910_05695	N6TGA5	J3JTI1	Uncharacterized protein.	BRO1 domain-containing protein.	0.689
D910_00332	D910_06141	N6TGA5	N6UMU8	Uncharacterized protein.	Uncharacterized protein; Belongs to the VPS28 family.	0.909
D910_00332	D910_06590	N6TGA5	U4UF40	Uncharacterized protein.	Hepatocyte growth factor-regulated tyrosine kinase substrate; Essential role in endosome membrane invagination and formation of multivesicular bodies, MVBs. Required during gastrulation and appears to regulate early embryonic signaling pathways. Inhibits tyrosine kinase receptor signaling by promoting degradation of the tyrosine-phosphorylated, active receptor, potentially by sorting activated receptors into MVBs. The MVBs are then trafficked to the lysosome where their contents are degraded.	0.733
D910_00332	D910_07890	N6TGA5	J3JXJ9	Uncharacterized protein.	Vacuolar-sorting protein SNF8; Component of the endosomal sorting complex required for transport II (ESCRT-II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs. Belongs to the SNF8 family.	0.907
D910_00332	D910_08125	N6TGA5	U4UA12	Uncharacterized protein.	Uncharacterized protein.	0.771
D910_00332	D910_08261	N6TGA5	U4UCZ9	Uncharacterized protein.	Uncharacterized protein.	0.896
D910_00332	D910_08742	N6TGA5	J3JT77	Uncharacterized protein.	Uncharacterized protein.	0.888
D910_00332	D910_08863	N6TGA5	U4UGQ6	Uncharacterized protein.	Uncharacterized protein.	0.889
D910_00332	D910_09371	N6TGA5	J3JUU3	Uncharacterized protein.	Uncharacterized protein.	0.963
D910_00332	D910_09870	N6TGA5	U4UHP9	Uncharacterized protein.	VPS37 C-terminal domain-containing protein.	0.892
D910_00332	D910_09976	N6TGA5	U4UFB0	Uncharacterized protein.	Uncharacterized protein; Belongs to the AAA ATPase family.	0.890
D910_00332	D910_09977	N6TGA5	U4URH2	Uncharacterized protein.	ATPase_AAA_core domain-containing protein.	0.843