37 items (Dendroctonus ponderosae) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	D910_04872	LIM zinc-binding domain-containing protein. (1221 aa)
	D910_04877	Calpain_III domain-containing protein. (173 aa)
	D910_07822	Uncharacterized protein. (610 aa)
	D910_09596	Protein kinase domain-containing protein. (694 aa)
	D910_06590	Hepatocyte growth factor-regulated tyrosine kinase substrate; Essential role in endosome membrane invagination and formation of multivesicular bodies, MVBs. Required during gastrulation and appears to regulate early embryonic signaling pathways. Inhibits tyrosine kinase receptor signaling by promoting degradation of the tyrosine-phosphorylated, active receptor, potentially by sorting activated receptors into MVBs. The MVBs are then trafficked to the lysosome where their contents are degraded. (659 aa)
	D910_10285	Uncharacterized protein; Belongs to the peptidase C14A family. (238 aa)
	D910_07745	Protein kinase domain-containing protein. (750 aa)
	D910_11864	Structural maintenance of chromosomes protein. (1269 aa)
	D910_03638	Uncharacterized protein. (220 aa)
	D910_11633	Uncharacterized protein; Belongs to the AAA ATPase family. (437 aa)
	D910_05303	Uncharacterized protein. (391 aa)
	D910_11634	Uncharacterized protein. (796 aa)
	D910_10371	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (147 aa)
	D910_00001	Uncharacterized protein. (254 aa)
	D910_09964	HMG box domain-containing protein. (274 aa)
	D910_07130	Uncharacterized protein. (279 aa)
	D910_08674	Caspase; Belongs to the peptidase C14A family. (425 aa)
	D910_00073	Uncharacterized protein. (431 aa)
	D910_00116	PID domain-containing protein. (362 aa)
	D910_12340	UBA_e1_C domain-containing protein; Belongs to the ubiquitin-activating E1 family. (1040 aa)
	D910_00954	FAD_binding_3 domain-containing protein. (434 aa)
	D910_00103	NR LBD domain-containing protein. (232 aa)
	D910_05588	Uncharacterized protein; Belongs to the peptidase C14A family. (323 aa)
	D910_10857	Uncharacterized protein. (1669 aa)
	D910_09851	Chromo domain-containing protein. (300 aa)
	D910_06141	Uncharacterized protein; Belongs to the VPS28 family. (214 aa)
	D910_02322	Uncharacterized protein. (3659 aa)
	D910_01673	Uncharacterized protein. (439 aa)
	D910_02321	Uncharacterized protein. (160 aa)
	D910_04871	BMERB domain-containing protein. (278 aa)
	D910_02044	Uncharacterized protein; Belongs to the peptidase C2 family. (978 aa)
	D910_05355	Uncharacterized protein. (505 aa)
	D910_04546	RRM domain-containing protein. (602 aa)
	D910_04551	Uncharacterized protein. (1503 aa)
	D910_05042	Uncharacterized protein. (813 aa)
	D910_05061	Phosphatidylinositol 3-kinase catalytic subunit type 3. (885 aa)
	D910_08603	Uncharacterized protein. (931 aa)

Your Current Organism:

Dendroctonus ponderosae

NCBI taxonomy Id: 77166
Other names: D. ponderosae, mountain pine beetle

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
D910_00073	D910_04551	U4UZ73	U4U953	Uncharacterized protein.	Uncharacterized protein.	0.999
D910_00073	D910_05061	U4UZ73	U4UAN3	Uncharacterized protein.	Phosphatidylinositol 3-kinase catalytic subunit type 3.	0.999
D910_00073	D910_11634	U4UZ73	U4UPF5	Uncharacterized protein.	Uncharacterized protein.	0.999
D910_00116	D910_08603	U4UZ55	U4UBG4	PID domain-containing protein.	Uncharacterized protein.	0.783
D910_00954	D910_04871	U4UU60	U4U0U2	FAD_binding_3 domain-containing protein.	BMERB domain-containing protein.	0.887
D910_00954	D910_04872	U4UU60	U4UC04	FAD_binding_3 domain-containing protein.	LIM zinc-binding domain-containing protein.	0.868
D910_02044	D910_03638	U4U1X6	J3JXU3	Uncharacterized protein; Belongs to the peptidase C2 family.	Uncharacterized protein.	0.426
D910_03638	D910_02044	J3JXU3	U4U1X6	Uncharacterized protein.	Uncharacterized protein; Belongs to the peptidase C2 family.	0.426
D910_03638	D910_04877	J3JXU3	U4UC08	Uncharacterized protein.	Calpain_III domain-containing protein.	0.426
D910_03638	D910_05303	J3JXU3	N6TTI4	Uncharacterized protein.	Uncharacterized protein.	0.904
D910_03638	D910_05355	J3JXU3	U4U4I4	Uncharacterized protein.	Uncharacterized protein.	0.580
D910_03638	D910_06141	J3JXU3	N6UMU8	Uncharacterized protein.	Uncharacterized protein; Belongs to the VPS28 family.	0.896
D910_03638	D910_06590	J3JXU3	U4UF40	Uncharacterized protein.	Hepatocyte growth factor-regulated tyrosine kinase substrate; Essential role in endosome membrane invagination and formation of multivesicular bodies, MVBs. Required during gastrulation and appears to regulate early embryonic signaling pathways. Inhibits tyrosine kinase receptor signaling by promoting degradation of the tyrosine-phosphorylated, active receptor, potentially by sorting activated receptors into MVBs. The MVBs are then trafficked to the lysosome where their contents are degraded.	0.756
D910_03638	D910_10857	J3JXU3	N6U701	Uncharacterized protein.	Uncharacterized protein.	0.995
D910_03638	D910_11633	J3JXU3	N6TV25	Uncharacterized protein.	Uncharacterized protein; Belongs to the AAA ATPase family.	0.968
D910_04551	D910_00073	U4U953	U4UZ73	Uncharacterized protein.	Uncharacterized protein.	0.999
D910_04551	D910_05061	U4U953	U4UAN3	Uncharacterized protein.	Phosphatidylinositol 3-kinase catalytic subunit type 3.	0.999
D910_04551	D910_11634	U4U953	U4UPF5	Uncharacterized protein.	Uncharacterized protein.	0.994
D910_04871	D910_00954	U4U0U2	U4UU60	BMERB domain-containing protein.	FAD_binding_3 domain-containing protein.	0.887
D910_04871	D910_04872	U4U0U2	U4UC04	BMERB domain-containing protein.	LIM zinc-binding domain-containing protein.	0.719