69 items (Dendroctonus ponderosae) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	D910_09617	PX domain-containing protein. (485 aa)
	D910_05310	Uncharacterized protein. (1465 aa)
	D910_05250	Uncharacterized protein. (217 aa)
	D910_04246	Dopey_N domain-containing protein. (118 aa)
	D910_05691	PX domain-containing protein. (558 aa)
	D910_02163	WH1 domain-containing protein. (469 aa)
	D910_02405	Uncharacterized protein. (113 aa)
	D910_00952	Uncharacterized protein. (1341 aa)
	D910_11299	Uncharacterized protein. (312 aa)
	D910_05064	Myosin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1218 aa)
	D910_11266	Uncharacterized protein. (415 aa)
	D910_00953	Dopey_N domain-containing protein. (771 aa)
	D910_05873	t-SNARE coiled-coil homology domain-containing protein. (216 aa)
	D910_10857	Uncharacterized protein. (1669 aa)
	D910_06666	t-SNARE coiled-coil homology domain-containing protein. (156 aa)
	D910_04488	Uncharacterized protein. (215 aa)
	D910_04292	Uncharacterized protein. (216 aa)
	D910_05600	Uncharacterized protein. (741 aa)
	D910_02994	Uncharacterized protein. (336 aa)
	D910_05332	Uncharacterized protein; Belongs to the small GTPase superfamily. Arf family. (184 aa)
	D910_07606	Vacuolar protein sorting-associated protein 29; Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway. (865 aa)
	D910_06422	Uncharacterized protein. (277 aa)
	D910_07340	F-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. (276 aa)
	D910_10470	Uncharacterized protein. (666 aa)
	D910_05918	Uncharacterized protein. (140 aa)
	D910_07900	Vesicle transport protein; May be involved in fusion of retrograde transport vesicles derived from an endocytic compartment with the Golgi complex. Belongs to the SFT2 family. (205 aa)
	D910_08804	PX domain-containing protein. (286 aa)
	D910_02192	Uncharacterized protein. (356 aa)
	D910_05664	Uncharacterized protein. (384 aa)
	D910_03933	Uncharacterized protein. (129 aa)
	D910_08164	ANK_REP_REGION domain-containing protein. (591 aa)
	D910_06893	Uncharacterized protein. (326 aa)
	D910_07993	PH domain-containing protein. (238 aa)
	D910_11972	Uncharacterized protein. (1041 aa)
	D910_01171	WH2 domain-containing protein. (444 aa)
	D910_09446	AP-3 complex subunit delta; Belongs to the adaptor complexes large subunit family. (929 aa)
	D910_11268	Uncharacterized protein. (669 aa)
	D910_12796	Uncharacterized protein. (2413 aa)
	D910_08162	Roc domain-containing protein. (384 aa)
	D910_11973	Uncharacterized protein. (742 aa)
	D910_06945	Vacuolar protein sorting-associated protein 35; Plays a role in vesicular protein sorting. (929 aa)
	D910_07404	Uncharacterized protein. (100 aa)
	D910_00068	Uncharacterized protein. (76 aa)
	D910_11974	Uncharacterized protein. (126 aa)
	D910_11250	Pep3_Vps18 domain-containing protein. (947 aa)
	D910_00249	Uncharacterized protein. (602 aa)
	D910_10483	GRIP domain-containing protein. (1247 aa)
	D910_10347	Uncharacterized protein. (929 aa)
	D910_12710	Vps53_N domain-containing protein. (536 aa)
	D910_10323	CTP_transf_like domain-containing protein. (512 aa)
	D910_09878	Uncharacterized protein. (106 aa)
	D910_12709	VPS53_C domain-containing protein. (175 aa)
	D910_12067	Uncharacterized protein. (168 aa)
	D910_06590	Hepatocyte growth factor-regulated tyrosine kinase substrate; Essential role in endosome membrane invagination and formation of multivesicular bodies, MVBs. Required during gastrulation and appears to regulate early embryonic signaling pathways. Inhibits tyrosine kinase receptor signaling by promoting degradation of the tyrosine-phosphorylated, active receptor, potentially by sorting activated receptors into MVBs. The MVBs are then trafficked to the lysosome where their contents are degraded. (659 aa)
	D910_05791	Uncharacterized protein. (1962 aa)
	D910_06208	Uncharacterized protein. (821 aa)
	D910_08163	Uncharacterized protein. (260 aa)
	D910_05105	Uncharacterized protein. (102 aa)
	D910_07366	RIC1 domain-containing protein. (1391 aa)
	D910_05106	Foie-gras_1 domain-containing protein. (1020 aa)
	D910_04248	Uncharacterized protein. (1342 aa)
	D910_04156	Uncharacterized protein. (225 aa)
	D910_04501	VPS9 domain-containing protein. (1438 aa)
	D910_06110	Uncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1158 aa)
	D910_07288	Uncharacterized protein. (715 aa)
	D910_03863	PX domain-containing protein. (167 aa)
	D910_06139	Uncharacterized protein. (193 aa)
	D910_05808	PX domain-containing protein. (452 aa)
	D910_03301	Uncharacterized protein. (1335 aa)

Your Current Organism:

Dendroctonus ponderosae

NCBI taxonomy Id: 77166
Other names: D. ponderosae, mountain pine beetle

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structured XML interaction data, according to the 'PSI-MI' data standard

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
D910_00952	D910_00953	U4TQK5	N6UI57	Uncharacterized protein.	Dopey_N domain-containing protein.	0.945
D910_00952	D910_04246	U4TQK5	U4U3G0	Uncharacterized protein.	Dopey_N domain-containing protein.	0.856
D910_00953	D910_00952	N6UI57	U4TQK5	Dopey_N domain-containing protein.	Uncharacterized protein.	0.945
D910_00953	D910_04246	N6UI57	U4U3G0	Dopey_N domain-containing protein.	Dopey_N domain-containing protein.	0.931
D910_00953	D910_04248	N6UI57	U4UA81	Dopey_N domain-containing protein.	Uncharacterized protein.	0.945
D910_00953	D910_05310	N6UI57	U4U4E8	Dopey_N domain-containing protein.	Uncharacterized protein.	0.945
D910_02163	D910_04156	U4TXK9	U4U9X0	WH1 domain-containing protein.	Uncharacterized protein.	0.770
D910_02994	D910_03863	N6TU98	U4U778	Uncharacterized protein.	PX domain-containing protein.	0.978
D910_02994	D910_04292	N6TU98	N6U275	Uncharacterized protein.	Uncharacterized protein.	0.517
D910_02994	D910_05691	N6TU98	U4U334	Uncharacterized protein.	PX domain-containing protein.	0.754
D910_02994	D910_05808	N6TU98	U4U5U2	Uncharacterized protein.	PX domain-containing protein.	0.616
D910_02994	D910_06945	N6TU98	U4UI68	Uncharacterized protein.	Vacuolar protein sorting-associated protein 35; Plays a role in vesicular protein sorting.	0.997
D910_02994	D910_07606	N6TU98	N6TII3	Uncharacterized protein.	Vacuolar protein sorting-associated protein 29; Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway.	0.994
D910_02994	D910_08804	N6TU98	J3JZ38	Uncharacterized protein.	PX domain-containing protein.	0.438
D910_02994	D910_09617	N6TU98	N6T3D5	Uncharacterized protein.	PX domain-containing protein.	0.958
D910_03301	D910_10483	U4U5L9	U4USN3	Uncharacterized protein.	GRIP domain-containing protein.	0.841
D910_03863	D910_02994	U4U778	N6TU98	PX domain-containing protein.	Uncharacterized protein.	0.978
D910_03863	D910_05691	U4U778	U4U334	PX domain-containing protein.	PX domain-containing protein.	0.742
D910_03863	D910_05808	U4U778	U4U5U2	PX domain-containing protein.	PX domain-containing protein.	0.644
D910_03863	D910_06590	U4U778	U4UF40	PX domain-containing protein.	Hepatocyte growth factor-regulated tyrosine kinase substrate; Essential role in endosome membrane invagination and formation of multivesicular bodies, MVBs. Required during gastrulation and appears to regulate early embryonic signaling pathways. Inhibits tyrosine kinase receptor signaling by promoting degradation of the tyrosine-phosphorylated, active receptor, potentially by sorting activated receptors into MVBs. The MVBs are then trafficked to the lysosome where their contents are degraded.	0.752