33 items (Dendroctonus ponderosae) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

Your Input:
	D910_09224	Uncharacterized protein; Belongs to the small GTPase superfamily. SAR1 family. (193 aa)
	D910_09171	Coatomer subunit beta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. (905 aa)
	D910_12071	Uncharacterized protein. (184 aa)
	D910_11224	Uncharacterized protein. (173 aa)
	D910_12481	NADH-cytochrome b5 reductase; Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. (313 aa)
	D910_11225	Uncharacterized protein. (177 aa)
	D910_11125	Uncharacterized protein. (227 aa)
	D910_07638	Uncharacterized protein. (706 aa)
	D910_07757	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (154 aa)
	D910_12347	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1715 aa)
	D910_09730	WD_REPEATS_REGION domain-containing protein; Belongs to the WD repeat SEC13 family. (331 aa)
	D910_10327	WD_REPEATS_REGION domain-containing protein. (994 aa)
	D910_10566	Uncharacterized protein. (1083 aa)
	D910_10657	Uncharacterized protein. (1072 aa)
	D910_05811	ENTH domain-containing protein. (472 aa)
	D910_00401	Protein transport protein SEC23; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules; Belongs to the SEC23/SEC24 family. SEC23 subfamily. (810 aa)
	D910_00676	ENTH domain-containing protein. (330 aa)
	D910_01975	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (157 aa)
	D910_11055	MHD domain-containing protein; Belongs to the adaptor complexes medium subunit family. (422 aa)
	D910_01923	DUF1681 domain-containing protein. (243 aa)
	D910_05319	Coatomer subunit delta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. (508 aa)
	D910_01542	Protein transport protein SEC23; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules; Belongs to the SEC23/SEC24 family. SEC23 subfamily. (776 aa)
	D910_03001	MHD domain-containing protein; Belongs to the adaptor complexes medium subunit family. (438 aa)
	D910_09097	WD_REPEATS_REGION domain-containing protein. (1158 aa)
	D910_04889	Coatomer subunit zeta; The zeta subunit may be involved in regulating the coat assembly and, hence, the rate of biosynthetic protein transport due to its association-dissociation properties with the coatomer complex. (173 aa)
	D910_11552	Alpha_adaptinC2 domain-containing protein. (937 aa)
	D910_03006	MFS domain-containing protein. (418 aa)
	D910_03913	Coatomer subunit epsilon; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. The coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. Belongs to the COPE family. (302 aa)
	D910_00660	MFS domain-containing protein. (153 aa)
	D910_02937	Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. (227 aa)
	D910_07175	Coatomer subunit gamma; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. (826 aa)
	D910_04042	AP-1 complex subunit gamma. (996 aa)
	D910_07408	Coatomer subunit beta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. (843 aa)

Your Current Organism:

Dendroctonus ponderosae

NCBI taxonomy Id: 77166
Other names: D. ponderosae, mountain pine beetle

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
D910_00401	D910_05319	U4TRT6	J3JWP1	Protein transport protein SEC23; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules; Belongs to the SEC23/SEC24 family. SEC23 subfamily.	Coatomer subunit delta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.	0.488
D910_00401	D910_07175	U4TRT6	U4U7D5	Protein transport protein SEC23; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules; Belongs to the SEC23/SEC24 family. SEC23 subfamily.	Coatomer subunit gamma; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.	0.618
D910_00401	D910_07408	U4TRT6	U4UAG9	Protein transport protein SEC23; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules; Belongs to the SEC23/SEC24 family. SEC23 subfamily.	Coatomer subunit beta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.	0.552
D910_00401	D910_09097	U4TRT6	N6TFP7	Protein transport protein SEC23; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules; Belongs to the SEC23/SEC24 family. SEC23 subfamily.	WD_REPEATS_REGION domain-containing protein.	0.738
D910_00401	D910_09171	U4TRT6	U4UNZ3	Protein transport protein SEC23; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules; Belongs to the SEC23/SEC24 family. SEC23 subfamily.	Coatomer subunit beta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.	0.513
D910_00401	D910_09224	U4TRT6	U4UP32	Protein transport protein SEC23; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules; Belongs to the SEC23/SEC24 family. SEC23 subfamily.	Uncharacterized protein; Belongs to the small GTPase superfamily. SAR1 family.	0.968
D910_00401	D910_09730	U4TRT6	U4UQK2	Protein transport protein SEC23; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules; Belongs to the SEC23/SEC24 family. SEC23 subfamily.	WD_REPEATS_REGION domain-containing protein; Belongs to the WD repeat SEC13 family.	0.978
D910_00401	D910_10327	U4TRT6	U4USE8	Protein transport protein SEC23; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules; Belongs to the SEC23/SEC24 family. SEC23 subfamily.	WD_REPEATS_REGION domain-containing protein.	0.975
D910_00401	D910_10566	U4TRT6	U4UT33	Protein transport protein SEC23; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules; Belongs to the SEC23/SEC24 family. SEC23 subfamily.	Uncharacterized protein.	0.984
D910_00401	D910_10657	U4TRT6	U4UTC1	Protein transport protein SEC23; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules; Belongs to the SEC23/SEC24 family. SEC23 subfamily.	Uncharacterized protein.	0.986
D910_00401	D910_12347	U4TRT6	U4UPP0	Protein transport protein SEC23; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules; Belongs to the SEC23/SEC24 family. SEC23 subfamily.	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	0.550
D910_00660	D910_03006	U4TZ37	U4TXQ2	MFS domain-containing protein.	MFS domain-containing protein.	0.947
D910_00676	D910_01975	U4TUH4	J3JU90	ENTH domain-containing protein.	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	0.738
D910_00676	D910_02937	U4TUH4	U4TZQ8	ENTH domain-containing protein.	Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family.	0.833
D910_00676	D910_03001	U4TUH4	J3JY16	ENTH domain-containing protein.	MHD domain-containing protein; Belongs to the adaptor complexes medium subunit family.	0.454
D910_00676	D910_04042	U4TUH4	U4U9M5	ENTH domain-containing protein.	AP-1 complex subunit gamma.	0.840
D910_00676	D910_07638	U4TUH4	U4UI51	ENTH domain-containing protein.	Uncharacterized protein.	0.653
D910_00676	D910_11055	U4TUH4	J3JW23	ENTH domain-containing protein.	MHD domain-containing protein; Belongs to the adaptor complexes medium subunit family.	0.451
D910_00676	D910_11552	U4TUH4	N6TXW3	ENTH domain-containing protein.	Alpha_adaptinC2 domain-containing protein.	0.596
D910_00676	D910_12347	U4TUH4	U4UPP0	ENTH domain-containing protein.	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	0.838