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D910_12066 D910_12066 D910_04373 D910_04373 D910_00863 D910_00863 D910_01503 D910_01503 D910_10003 D910_10003 D910_08690 D910_08690 D910_10002 D910_10002 D910_02333 D910_02333 D910_12600 D910_12600 D910_06084 D910_06084 D910_05041 D910_05041 D910_12347 D910_12347 D910_06590 D910_06590
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
D910_12066Arrestin_C domain-containing protein. (252 aa)
D910_04373E3 ubiquitin-protein ligase. (858 aa)
D910_00863Uncharacterized protein. (289 aa)
D910_01503Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (152 aa)
D910_10003HECT domain-containing protein. (238 aa)
D910_08690Arrestin_C domain-containing protein. (430 aa)
D910_10002Uncharacterized protein. (597 aa)
D910_02333Uncharacterized protein. (201 aa)
D910_12600Uncharacterized protein. (135 aa)
D910_06084Arrestin_C domain-containing protein. (379 aa)
D910_05041Arrestin_C domain-containing protein. (355 aa)
D910_12347Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1715 aa)
D910_06590Hepatocyte growth factor-regulated tyrosine kinase substrate; Essential role in endosome membrane invagination and formation of multivesicular bodies, MVBs. Required during gastrulation and appears to regulate early embryonic signaling pathways. Inhibits tyrosine kinase receptor signaling by promoting degradation of the tyrosine-phosphorylated, active receptor, potentially by sorting activated receptors into MVBs. The MVBs are then trafficked to the lysosome where their contents are degraded. (659 aa)
Your Current Organism:
Dendroctonus ponderosae
NCBI taxonomy Id: 77166
Other names: D. ponderosae, mountain pine beetle
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