25 items (Dendroctonus ponderosae) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	D910_10949	Uncharacterized protein. (112 aa)
	D910_08742	Uncharacterized protein. (212 aa)
	D910_09371	Uncharacterized protein. (223 aa)
	D910_06380	Annexin. (323 aa)
	D910_10140	Uncharacterized protein. (206 aa)
	D910_07162	Uncharacterized protein. (155 aa)
	D910_07890	Vacuolar-sorting protein SNF8; Component of the endosomal sorting complex required for transport II (ESCRT-II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs. Belongs to the SNF8 family. (252 aa)
	D910_03638	Uncharacterized protein. (220 aa)
	D910_03047	GLUE N-terminal domain-containing protein. (391 aa)
	D910_10059	Uncharacterized protein. (481 aa)
	D910_12202	Uncharacterized protein. (288 aa)
	D910_00332	Uncharacterized protein. (219 aa)
	D910_06587	Uncharacterized protein. (392 aa)
	D910_04498	Uncharacterized protein. (215 aa)
	D910_10857	Uncharacterized protein. (1669 aa)
	D910_06141	Uncharacterized protein; Belongs to the VPS28 family. (214 aa)
	D910_02124	Uncharacterized protein. (212 aa)
	D910_05355	Uncharacterized protein. (505 aa)
	D910_05390	Uncharacterized protein. (250 aa)
	D910_08261	Uncharacterized protein. (177 aa)
	D910_06590	Hepatocyte growth factor-regulated tyrosine kinase substrate; Essential role in endosome membrane invagination and formation of multivesicular bodies, MVBs. Required during gastrulation and appears to regulate early embryonic signaling pathways. Inhibits tyrosine kinase receptor signaling by promoting degradation of the tyrosine-phosphorylated, active receptor, potentially by sorting activated receptors into MVBs. The MVBs are then trafficked to the lysosome where their contents are degraded. (659 aa)
	D910_08863	Uncharacterized protein. (347 aa)
	D910_10100	Uncharacterized protein. (365 aa)
	D910_09516	Uncharacterized protein. (3759 aa)
	D910_11162	Uncharacterized protein. (427 aa)

Your Current Organism:

Dendroctonus ponderosae

NCBI taxonomy Id: 77166
Other names: D. ponderosae, mountain pine beetle

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structured XML interaction data, according to the 'PSI-MI' data standard

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a flat-file format describing the coordinates and colors of nodes in the network

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
D910_00332	D910_02124	N6TGA5	U4TT48	Uncharacterized protein.	Uncharacterized protein.	0.987
D910_00332	D910_03047	N6TGA5	J3JYD3	Uncharacterized protein.	GLUE N-terminal domain-containing protein.	0.896
D910_00332	D910_03638	N6TGA5	J3JXU3	Uncharacterized protein.	Uncharacterized protein.	0.997
D910_00332	D910_05355	N6TGA5	U4U4I4	Uncharacterized protein.	Uncharacterized protein.	0.663
D910_00332	D910_05390	N6TGA5	U4UBM3	Uncharacterized protein.	Uncharacterized protein.	0.997
D910_00332	D910_06141	N6TGA5	N6UMU8	Uncharacterized protein.	Uncharacterized protein; Belongs to the VPS28 family.	0.909
D910_00332	D910_06590	N6TGA5	U4UF40	Uncharacterized protein.	Hepatocyte growth factor-regulated tyrosine kinase substrate; Essential role in endosome membrane invagination and formation of multivesicular bodies, MVBs. Required during gastrulation and appears to regulate early embryonic signaling pathways. Inhibits tyrosine kinase receptor signaling by promoting degradation of the tyrosine-phosphorylated, active receptor, potentially by sorting activated receptors into MVBs. The MVBs are then trafficked to the lysosome where their contents are degraded.	0.733
D910_00332	D910_07890	N6TGA5	J3JXJ9	Uncharacterized protein.	Vacuolar-sorting protein SNF8; Component of the endosomal sorting complex required for transport II (ESCRT-II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs. Belongs to the SNF8 family.	0.907
D910_00332	D910_08261	N6TGA5	U4UCZ9	Uncharacterized protein.	Uncharacterized protein.	0.896
D910_00332	D910_08742	N6TGA5	J3JT77	Uncharacterized protein.	Uncharacterized protein.	0.888
D910_00332	D910_08863	N6TGA5	U4UGQ6	Uncharacterized protein.	Uncharacterized protein.	0.889
D910_00332	D910_09371	N6TGA5	J3JUU3	Uncharacterized protein.	Uncharacterized protein.	0.963
D910_00332	D910_10100	N6TGA5	U4UIE7	Uncharacterized protein.	Uncharacterized protein.	0.955
D910_00332	D910_10140	N6TGA5	J3JW90	Uncharacterized protein.	Uncharacterized protein.	0.976
D910_00332	D910_10857	N6TGA5	N6U701	Uncharacterized protein.	Uncharacterized protein.	0.442
D910_00332	D910_11162	N6TGA5	U4UUL4	Uncharacterized protein.	Uncharacterized protein.	0.966
D910_00332	D910_12202	N6TGA5	N6T820	Uncharacterized protein.	Uncharacterized protein.	0.830
D910_02124	D910_00332	U4TT48	N6TGA5	Uncharacterized protein.	Uncharacterized protein.	0.987
D910_02124	D910_03047	U4TT48	J3JYD3	Uncharacterized protein.	GLUE N-terminal domain-containing protein.	0.987
D910_02124	D910_03638	U4TT48	J3JXU3	Uncharacterized protein.	Uncharacterized protein.	0.995