93 items (Dendroctonus ponderosae) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	D910_03760	Importin N-terminal domain-containing protein. (1086 aa)
	D910_04004	Uncharacterized protein. (486 aa)
	D910_00514	Defective in cullin neddylation protein; Neddylation of cullins play an essential role in the regulation of SCF-type complexes activity. (310 aa)
	D910_05218	Uncharacterized protein. (201 aa)
	D910_01950	Uncharacterized protein. (568 aa)
	D910_04430	SH3 domain-containing protein. (465 aa)
	D910_05411	Uncharacterized protein. (352 aa)
	D910_06681	Rab proteins geranylgeranyltransferase component A; Substrate-binding subunit (component A) of the Rab geranylgeranyltransferase (GGTase) complex. Binds unprenylated Rab proteins and presents the substrate peptide to the catalytic component B. The component A is thought to be regenerated by transferring its prenylated Rab back to the donor membrane. (528 aa)
	D910_02820	F-box domain-containing protein. (356 aa)
	D910_06730	Uncharacterized protein. (693 aa)
	D910_05212	Uncharacterized protein. (177 aa)
	D910_07587	Uncharacterized protein. (1244 aa)
	D910_04394	Uncharacterized protein. (391 aa)
	D910_06834	RanGAP1_C domain-containing protein. (559 aa)
	D910_07580	TPR_REGION domain-containing protein. (927 aa)
	D910_05220	ANK_REP_REGION domain-containing protein. (632 aa)
	D910_08518	Tetraspanin. (318 aa)
	D910_05219	Uncharacterized protein. (769 aa)
	D910_05756	Uncharacterized protein. (819 aa)
	D910_09442	Uncharacterized protein; Belongs to the STXBP/unc-18/SEC1 family. (545 aa)
	D910_10401	Uncharacterized protein. (535 aa)
	D910_10438	Uncharacterized protein. (86 aa)
	D910_10476	Fe2OG dioxygenase domain-containing protein. (682 aa)
	D910_10486	Photolyase/cryptochrome alpha/beta domain-containing protein. (509 aa)
	D910_11332	Headcase domain-containing protein. (188 aa)
	D910_07958	Uncharacterized protein. (1029 aa)
	D910_11374	Uncharacterized protein. (920 aa)
	D910_08576	WW domain-containing protein. (94 aa)
	D910_12457	Uncharacterized protein. (344 aa)
	D910_11814	Uncharacterized protein. (245 aa)
	D910_08979	HATPase_c domain-containing protein. (781 aa)
	D910_12056	Uncharacterized protein. (613 aa)
	D910_12347	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1715 aa)
	D910_01111	Uncharacterized protein. (68 aa)
	D910_01171	WH2 domain-containing protein. (444 aa)
	D910_09724	Uncharacterized protein. (934 aa)
	D910_09972	Guanylate cyclase domain-containing protein. (1737 aa)
	D910_12456	RING-type domain-containing protein. (367 aa)
	D910_10284	PDZ domain-containing protein. (621 aa)
	D910_00249	Uncharacterized protein. (602 aa)
	D910_00310	Uncharacterized protein. (674 aa)
	D910_10780	Phosphodiesterase. (928 aa)
	D910_00554	Uncharacterized protein. (235 aa)
	D910_11339	Uncharacterized protein. (396 aa)
	D910_11813	Uncharacterized protein; Belongs to the MAGUK family. (497 aa)
	D910_11818	Uncharacterized protein. (97 aa)
	D910_12381	Uncharacterized protein. (309 aa)
	D910_12350	CULLIN_2 domain-containing protein; Belongs to the cullin family. (769 aa)
	D910_08874	HATPase_c domain-containing protein. (709 aa)
	D910_02372	Uncharacterized protein. (215 aa)
	D910_10074	Vacuolar proton pump subunit B; Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase; Belongs to the ATPase alpha/beta chains family. (492 aa)
	D910_02531	Uncharacterized protein. (259 aa)
	D910_03933	Uncharacterized protein. (129 aa)
	D910_12382	Uncharacterized protein. (205 aa)
	D910_06362	Phosphodiesterase. (520 aa)
	D910_12524	Uncharacterized protein. (909 aa)
	D910_06602	Uncharacterized protein. (230 aa)
	D910_08351	ANK_REP_REGION domain-containing protein. (594 aa)
	D910_11495	Uncharacterized protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (532 aa)
	D910_11928	Uncharacterized protein. (317 aa)
	D910_10671	Uncharacterized protein. (129 aa)
	D910_01114	RING-type domain-containing protein. (380 aa)
	D910_08934	Uncharacterized protein. (191 aa)
	D910_02066	Uncharacterized protein. (462 aa)
	D910_03275	Uncharacterized protein. (255 aa)
	D910_01765	Uncharacterized protein. (658 aa)
	D910_02023	Uncharacterized protein. (118 aa)
	D910_04642	Uncharacterized protein. (321 aa)
	D910_06880	Uncharacterized protein. (124 aa)
	D910_09148	Uncharacterized protein. (636 aa)
	D910_10511	Uncharacterized protein; Belongs to the small GTPase superfamily. Arf family. (186 aa)
	D910_05697	Uncharacterized protein. (254 aa)
	D910_06529	SUN domain-containing protein. (309 aa)
	D910_03757	Protein disulfide-isomerase. (497 aa)
	D910_05700	RING-type domain-containing protein; Belongs to the FPP/GGPP synthase family. (463 aa)
	D910_11534	Sodium/hydrogen exchanger. (570 aa)
	D910_07104	Uncharacterized protein. (699 aa)
	D910_07868	Uncharacterized protein. (610 aa)
	D910_02050	Uncharacterized protein. (1070 aa)
	D910_10016	Atx10homo_assoc domain-containing protein. (416 aa)
	D910_01503	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (152 aa)
	D910_07869	ArgoN domain-containing protein. (151 aa)
	D910_04698	Uncharacterized protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (550 aa)
	D910_00615	Uncharacterized protein. (699 aa)
	D910_00273	Uncharacterized protein. (292 aa)
	D910_01303	Uncharacterized protein. (285 aa)
	D910_00338	AAA domain-containing protein. (474 aa)
	D910_01536	B30.2/SPRY domain-containing protein. (232 aa)
	D910_03209	ADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family. GMF subfamily. (138 aa)
	D910_02802	FIP-RBD domain-containing protein. (335 aa)
	D910_02515	Uncharacterized protein. (351 aa)
	D910_02872	PX domain-containing protein; Belongs to the tetraspanin (TM4SF) family. (682 aa)
	D910_03109	Oxysterol-binding protein; Belongs to the OSBP family. (931 aa)

Your Current Organism:

Dendroctonus ponderosae

NCBI taxonomy Id: 77166
Other names: D. ponderosae, mountain pine beetle

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
D910_00514	D910_12350	U4U0N5	U4UXQ9	Defective in cullin neddylation protein; Neddylation of cullins play an essential role in the regulation of SCF-type complexes activity.	CULLIN_2 domain-containing protein; Belongs to the cullin family.	0.779
D910_01114	D910_11374	N6TFI7	U4ULU2	RING-type domain-containing protein.	Uncharacterized protein.	0.660
D910_01303	D910_01950	U4TTA6	U4U3F7	Uncharacterized protein.	Uncharacterized protein.	0.615
D910_01303	D910_11374	U4TTA6	U4ULU2	Uncharacterized protein.	Uncharacterized protein.	0.453
D910_01503	D910_12347	N6UJ54	U4UPP0	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	0.445
D910_01950	D910_01303	U4U3F7	U4TTA6	Uncharacterized protein.	Uncharacterized protein.	0.615
D910_01950	D910_11374	U4U3F7	U4ULU2	Uncharacterized protein.	Uncharacterized protein.	0.830
D910_02372	D910_02802	J3JV86	U4TX67	Uncharacterized protein.	FIP-RBD domain-containing protein.	0.987
D910_02372	D910_06681	J3JV86	U4U5Z3	Uncharacterized protein.	Rab proteins geranylgeranyltransferase component A; Substrate-binding subunit (component A) of the Rab geranylgeranyltransferase (GGTase) complex. Binds unprenylated Rab proteins and presents the substrate peptide to the catalytic component B. The component A is thought to be regenerated by transferring its prenylated Rab back to the donor membrane.	0.756
D910_02372	D910_08874	J3JV86	J3JU00	Uncharacterized protein.	HATPase_c domain-containing protein.	0.554
D910_02372	D910_12347	J3JV86	U4UPP0	Uncharacterized protein.	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	0.794
D910_02802	D910_02372	U4TX67	J3JV86	FIP-RBD domain-containing protein.	Uncharacterized protein.	0.987
D910_02820	D910_12350	U4U631	U4UXQ9	F-box domain-containing protein.	CULLIN_2 domain-containing protein; Belongs to the cullin family.	0.442
D910_02872	D910_12347	U4TZK6	U4UPP0	PX domain-containing protein; Belongs to the tetraspanin (TM4SF) family.	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	0.732
D910_03757	D910_08979	N6U4S7	U4UNB6	Protein disulfide-isomerase.	HATPase_c domain-containing protein.	0.782
D910_03757	D910_10074	N6U4S7	J3JVB5	Protein disulfide-isomerase.	Vacuolar proton pump subunit B; Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase; Belongs to the ATPase alpha/beta chains family.	0.720
D910_03760	D910_07868	U4TZW4	N6UGE9	Importin N-terminal domain-containing protein.	Uncharacterized protein.	0.661
D910_03760	D910_07869	U4TZW4	N6UJJ3	Importin N-terminal domain-containing protein.	ArgoN domain-containing protein.	0.661
D910_03760	D910_11374	U4TZW4	U4ULU2	Importin N-terminal domain-containing protein.	Uncharacterized protein.	0.452
D910_03933	D910_09442	N6SRH7	U4UGG4	Uncharacterized protein.	Uncharacterized protein; Belongs to the STXBP/unc-18/SEC1 family.	0.797