39 items (Dendroctonus ponderosae) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	D910_02474	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (590 aa)
	D910_09322	Uncharacterized protein. (489 aa)
	D910_09224	Uncharacterized protein; Belongs to the small GTPase superfamily. SAR1 family. (193 aa)
	D910_11967	Uncharacterized protein. (652 aa)
	D910_07938	AAA_28 domain-containing protein. (360 aa)
	D910_06945	Vacuolar protein sorting-associated protein 35; Plays a role in vesicular protein sorting. (929 aa)
	D910_09895	Flot domain-containing protein; Belongs to the band 7/mec-2 family. Flotillin subfamily. (285 aa)
	D910_09329	PCM1_C domain-containing protein. (1414 aa)
	D910_06590	Hepatocyte growth factor-regulated tyrosine kinase substrate; Essential role in endosome membrane invagination and formation of multivesicular bodies, MVBs. Required during gastrulation and appears to regulate early embryonic signaling pathways. Inhibits tyrosine kinase receptor signaling by promoting degradation of the tyrosine-phosphorylated, active receptor, potentially by sorting activated receptors into MVBs. The MVBs are then trafficked to the lysosome where their contents are degraded. (659 aa)
	D910_05659	Peptidase M12B domain-containing protein. (695 aa)
	D910_06913	FCP1 homology domain-containing protein. (484 aa)
	D910_05076	Uncharacterized protein. (1579 aa)
	D910_04318	Uncharacterized protein. (361 aa)
	D910_08140	Uncharacterized protein. (405 aa)
	D910_04156	Uncharacterized protein. (225 aa)
	D910_03863	PX domain-containing protein. (167 aa)
	D910_03087	Uncharacterized protein. (370 aa)
	D910_02850	WD_REPEATS_REGION domain-containing protein. (1494 aa)
	D910_03301	Uncharacterized protein. (1335 aa)
	D910_04783	Uncharacterized protein. (379 aa)
	D910_01086	Uncharacterized protein. (252 aa)
	D910_04494	Uncharacterized protein. (475 aa)
	D910_02556	Sec16 domain-containing protein. (1717 aa)
	D910_00217	Mab-21 domain-containing protein. (548 aa)
	D910_01971	Uncharacterized protein. (72 aa)
	D910_01131	TPR_MLP1_2 domain-containing protein. (2339 aa)
	D910_10857	Uncharacterized protein. (1669 aa)
	D910_02719	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (626 aa)
	D910_12697	Uncharacterized protein. (462 aa)
	D910_03488	Uncharacterized protein. (543 aa)
	D910_04642	Uncharacterized protein. (321 aa)
	D910_11968	C2 domain-containing protein. (264 aa)
	D910_02577	Uncharacterized protein. (239 aa)
	D910_02372	Uncharacterized protein. (215 aa)
	D910_10216	ADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family. (148 aa)
	D910_09480	Uncharacterized protein. (118 aa)
	D910_12829	Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (716 aa)
	D910_11250	Pep3_Vps18 domain-containing protein. (947 aa)
	D910_12827	Uncharacterized protein. (2129 aa)

Your Current Organism:

Dendroctonus ponderosae

NCBI taxonomy Id: 77166
Other names: D. ponderosae, mountain pine beetle

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
D910_01131	D910_03301	N6UDE0	U4U5L9	TPR_MLP1_2 domain-containing protein.	Uncharacterized protein.	0.957
D910_02372	D910_06945	J3JV86	U4UI68	Uncharacterized protein.	Vacuolar protein sorting-associated protein 35; Plays a role in vesicular protein sorting.	0.648
D910_02372	D910_10857	J3JV86	N6U701	Uncharacterized protein.	Uncharacterized protein.	0.437
D910_02372	D910_12827	J3JV86	U4UYT9	Uncharacterized protein.	Uncharacterized protein.	0.821
D910_02474	D910_02850	U4U371	U4U656	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	WD_REPEATS_REGION domain-containing protein.	0.480
D910_02556	D910_03863	U4TU95	U4U778	Sec16 domain-containing protein.	PX domain-containing protein.	0.561
D910_02556	D910_09224	U4TU95	U4UP32	Sec16 domain-containing protein.	Uncharacterized protein; Belongs to the small GTPase superfamily. SAR1 family.	0.943
D910_02719	D910_02850	N6U0Z3	U4U656	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	WD_REPEATS_REGION domain-containing protein.	0.480
D910_02850	D910_02474	U4U656	U4U371	WD_REPEATS_REGION domain-containing protein.	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.480
D910_02850	D910_02719	U4U656	N6U0Z3	WD_REPEATS_REGION domain-containing protein.	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.480
D910_03301	D910_01131	U4U5L9	N6UDE0	Uncharacterized protein.	TPR_MLP1_2 domain-containing protein.	0.957
D910_03488	D910_03863	N6TS54	U4U778	Uncharacterized protein.	PX domain-containing protein.	0.921
D910_03488	D910_06945	N6TS54	U4UI68	Uncharacterized protein.	Vacuolar protein sorting-associated protein 35; Plays a role in vesicular protein sorting.	0.842
D910_03863	D910_02556	U4U778	U4TU95	PX domain-containing protein.	Sec16 domain-containing protein.	0.561
D910_03863	D910_03488	U4U778	N6TS54	PX domain-containing protein.	Uncharacterized protein.	0.921
D910_03863	D910_06590	U4U778	U4UF40	PX domain-containing protein.	Hepatocyte growth factor-regulated tyrosine kinase substrate; Essential role in endosome membrane invagination and formation of multivesicular bodies, MVBs. Required during gastrulation and appears to regulate early embryonic signaling pathways. Inhibits tyrosine kinase receptor signaling by promoting degradation of the tyrosine-phosphorylated, active receptor, potentially by sorting activated receptors into MVBs. The MVBs are then trafficked to the lysosome where their contents are degraded.	0.752
D910_03863	D910_06945	U4U778	U4UI68	PX domain-containing protein.	Vacuolar protein sorting-associated protein 35; Plays a role in vesicular protein sorting.	0.992
D910_03863	D910_12827	U4U778	U4UYT9	PX domain-containing protein.	Uncharacterized protein.	0.723
D910_06590	D910_03863	U4UF40	U4U778	Hepatocyte growth factor-regulated tyrosine kinase substrate; Essential role in endosome membrane invagination and formation of multivesicular bodies, MVBs. Required during gastrulation and appears to regulate early embryonic signaling pathways. Inhibits tyrosine kinase receptor signaling by promoting degradation of the tyrosine-phosphorylated, active receptor, potentially by sorting activated receptors into MVBs. The MVBs are then trafficked to the lysosome where their contents are degraded.	PX domain-containing protein.	0.752
D910_06590	D910_06945	U4UF40	U4UI68	Hepatocyte growth factor-regulated tyrosine kinase substrate; Essential role in endosome membrane invagination and formation of multivesicular bodies, MVBs. Required during gastrulation and appears to regulate early embryonic signaling pathways. Inhibits tyrosine kinase receptor signaling by promoting degradation of the tyrosine-phosphorylated, active receptor, potentially by sorting activated receptors into MVBs. The MVBs are then trafficked to the lysosome where their contents are degraded.	Vacuolar protein sorting-associated protein 35; Plays a role in vesicular protein sorting.	0.672