106 items (Dendroctonus ponderosae) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	D910_07875	PDZ domain-containing protein. (208 aa)
	D910_05016	Cyclic nucleotide-binding domain-containing protein. (368 aa)
	D910_01135	C2 domain-containing protein. (156 aa)
	D910_08309	Uncharacterized protein. (488 aa)
	D910_08568	Uncharacterized protein. (546 aa)
	D910_07876	Uncharacterized protein. (490 aa)
	D910_06590	Hepatocyte growth factor-regulated tyrosine kinase substrate; Essential role in endosome membrane invagination and formation of multivesicular bodies, MVBs. Required during gastrulation and appears to regulate early embryonic signaling pathways. Inhibits tyrosine kinase receptor signaling by promoting degradation of the tyrosine-phosphorylated, active receptor, potentially by sorting activated receptors into MVBs. The MVBs are then trafficked to the lysosome where their contents are degraded. (659 aa)
	D910_09976	Uncharacterized protein; Belongs to the AAA ATPase family. (180 aa)
	D910_06761	Uncharacterized protein. (295 aa)
	D910_09624	ZZ-type domain-containing protein. (710 aa)
	D910_09895	Flot domain-containing protein; Belongs to the band 7/mec-2 family. Flotillin subfamily. (285 aa)
	D910_09935	Uncharacterized protein. (756 aa)
	D910_06945	Vacuolar protein sorting-associated protein 35; Plays a role in vesicular protein sorting. (929 aa)
	D910_09605	Uncharacterized protein. (298 aa)
	D910_09650	Uncharacterized protein. (189 aa)
	D910_07904	C2 domain-containing protein. (124 aa)
	D910_10233	Uncharacterized protein. (779 aa)
	D910_07908	C2 domain-containing protein. (164 aa)
	D910_11404	Uncharacterized protein. (313 aa)
	D910_09983	DUF3456 domain-containing protein. (190 aa)
	D910_00342	Uncharacterized protein. (241 aa)
	D910_12829	Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (716 aa)
	D910_10566	Uncharacterized protein. (1083 aa)
	D910_01759	DH domain-containing protein. (356 aa)
	D910_00484	C2 domain-containing protein. (222 aa)
	D910_10894	Uncharacterized protein. (506 aa)
	D910_01822	DH domain-containing protein. (345 aa)
	D910_11250	Pep3_Vps18 domain-containing protein. (947 aa)
	D910_11382	Uncharacterized protein. (259 aa)
	D910_12325	FYVE-type domain-containing protein. (242 aa)
	D910_00959	ZZ-type domain-containing protein. (409 aa)
	D910_08352	Septin-type G domain-containing protein; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (376 aa)
	D910_08490	tRNA-binding domain-containing protein. (313 aa)
	D910_11937	Uncharacterized protein. (2377 aa)
	D910_09358	Uncharacterized protein. (519 aa)
	D910_09312	Uncharacterized protein. (243 aa)
	D910_09322	Uncharacterized protein. (489 aa)
	D910_12367	Uncharacterized protein. (1015 aa)
	D910_11938	Uncharacterized protein. (254 aa)
	D910_03786	Elp3 domain-containing protein. (334 aa)
	D910_04428	Uncharacterized protein. (185 aa)
	D910_04482	TGF_BETA_2 domain-containing protein. (417 aa)
	D910_07248	TGF_BETA_2 domain-containing protein. (367 aa)
	D910_05626	Uncharacterized protein. (470 aa)
	D910_11178	Uncharacterized protein. (210 aa)
	D910_01971	Uncharacterized protein. (72 aa)
	D910_05064	Myosin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1218 aa)
	D910_04176	Uncharacterized protein. (364 aa)
	D910_07874	Uncharacterized protein. (318 aa)
	D910_01563	Uncharacterized protein. (457 aa)
	D910_00401	Protein transport protein SEC23; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules; Belongs to the SEC23/SEC24 family. SEC23 subfamily. (810 aa)
	D910_01423	G_PROTEIN_RECEP_F3_4 domain-containing protein. (693 aa)
	D910_01438	Uncharacterized protein. (130 aa)
	D910_01952	Uncharacterized protein. (862 aa)
	D910_02878	Uncharacterized protein. (323 aa)
	D910_01136	Uncharacterized protein. (79 aa)
	D910_00205	ANF_receptor domain-containing protein. (334 aa)
	D910_01439	G_PROTEIN_RECEP_F3_4 domain-containing protein. (687 aa)
	D910_03508	Uncharacterized protein. (354 aa)
	D910_03187	Uncharacterized protein. (287 aa)
	D910_01493	Uncharacterized protein. (150 aa)
	D910_02872	PX domain-containing protein; Belongs to the tetraspanin (TM4SF) family. (682 aa)
	D910_04494	Uncharacterized protein. (475 aa)
	D910_04603	DH domain-containing protein. (404 aa)
	D910_03999	Uncharacterized protein. (233 aa)
	D910_01936	TLDc domain-containing protein. (394 aa)
	D910_05252	Uncharacterized protein. (250 aa)
	D910_04547	LLGL domain-containing protein. (526 aa)
	D910_05790	Uncharacterized protein. (79 aa)
	D910_00641	MFS domain-containing protein; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (561 aa)
	D910_04783	Uncharacterized protein. (379 aa)
	D910_05326	Uncharacterized protein. (462 aa)
	D910_07052	Uncharacterized protein. (636 aa)
	D910_03863	PX domain-containing protein. (167 aa)
	D910_03895	PX domain-containing protein. (415 aa)
	D910_05764	C2 domain-containing protein. (116 aa)
	D910_05789	Rhomboid domain-containing protein. (720 aa)
	D910_04443	G_PROTEIN_RECEP_F1_2 domain-containing protein. (538 aa)
	D910_07986	Fmp27_GFWDK domain-containing protein. (1454 aa)
	D910_08140	Uncharacterized protein. (405 aa)
	D910_04318	Uncharacterized protein. (361 aa)
	D910_06700	Uncharacterized protein. (680 aa)
	D910_05659	Peptidase M12B domain-containing protein. (695 aa)
	D910_10216	ADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family. (148 aa)
	D910_09763	Uncharacterized protein. (202 aa)
	D910_08175	Septin-type G domain-containing protein; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (357 aa)
	D910_02577	Uncharacterized protein. (239 aa)
	D910_01542	Protein transport protein SEC23; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules; Belongs to the SEC23/SEC24 family. SEC23 subfamily. (776 aa)
	D910_02517	Uncharacterized protein. (425 aa)
	D910_05017	Ion_trans domain-containing protein. (150 aa)
	D910_02040	IGFBP N-terminal domain-containing protein. (53 aa)
	D910_03509	Uncharacterized protein. (636 aa)
	D910_01998	Uncharacterized protein. (1326 aa)
	D910_01214	C2 domain-containing protein. (160 aa)
	D910_10896	Uncharacterized protein. (470 aa)
	D910_07354	Protein kinase domain-containing protein. (417 aa)
	D910_12127	Uncharacterized protein. (184 aa)
	D910_07988	Uncharacterized protein. (253 aa)
	D910_04642	Uncharacterized protein. (321 aa)
	D910_03488	Uncharacterized protein. (543 aa)
	D910_08257	Cyclic nucleotide-binding domain-containing protein. (213 aa)
	D910_02000	RING-type domain-containing protein. (142 aa)
	D910_06982	Uncharacterized protein. (203 aa)
	D910_10857	Uncharacterized protein. (1669 aa)
	D910_08377	BHLH domain-containing protein. (150 aa)
	D910_05806	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (442 aa)

Your Current Organism:

Dendroctonus ponderosae

NCBI taxonomy Id: 77166
Other names: D. ponderosae, mountain pine beetle

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
D910_00205	D910_01423	U4TVV7	U4TTJ0	ANF_receptor domain-containing protein.	G_PROTEIN_RECEP_F3_4 domain-containing protein.	0.845
D910_00205	D910_01439	U4TVV7	U4TVW3	ANF_receptor domain-containing protein.	G_PROTEIN_RECEP_F3_4 domain-containing protein.	0.790
D910_00342	D910_04547	U4URS0	U4U245	Uncharacterized protein.	LLGL domain-containing protein.	0.896
D910_00342	D910_05252	U4URS0	U4U1Z9	Uncharacterized protein.	Uncharacterized protein.	0.597
D910_00401	D910_05806	U4TRT6	N6UAM1	Protein transport protein SEC23; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules; Belongs to the SEC23/SEC24 family. SEC23 subfamily.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.441
D910_00401	D910_09763	U4TRT6	J3JV35	Protein transport protein SEC23; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules; Belongs to the SEC23/SEC24 family. SEC23 subfamily.	Uncharacterized protein.	0.723
D910_00401	D910_10566	U4TRT6	U4UT33	Protein transport protein SEC23; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules; Belongs to the SEC23/SEC24 family. SEC23 subfamily.	Uncharacterized protein.	0.984
D910_00484	D910_11178	U4UTN3	N6UEM8	C2 domain-containing protein.	Uncharacterized protein.	0.570
D910_00959	D910_09624	U4V065	U4UH02	ZZ-type domain-containing protein.	ZZ-type domain-containing protein.	0.826
D910_01135	D910_05764	U4UCS3	U4U7T4	C2 domain-containing protein.	C2 domain-containing protein.	0.914
D910_01214	D910_05764	N6T9P1	U4U7T4	C2 domain-containing protein.	C2 domain-containing protein.	0.930
D910_01423	D910_00205	U4TTJ0	U4TVV7	G_PROTEIN_RECEP_F3_4 domain-containing protein.	ANF_receptor domain-containing protein.	0.845
D910_01439	D910_00205	U4TVW3	U4TVV7	G_PROTEIN_RECEP_F3_4 domain-containing protein.	ANF_receptor domain-containing protein.	0.790
D910_01493	D910_01936	U4TYB1	U4U1N1	Uncharacterized protein.	TLDc domain-containing protein.	0.542
D910_01542	D910_05806	J3JX23	N6UAM1	Protein transport protein SEC23; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules; Belongs to the SEC23/SEC24 family. SEC23 subfamily.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.441
D910_01542	D910_09763	J3JX23	J3JV35	Protein transport protein SEC23; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules; Belongs to the SEC23/SEC24 family. SEC23 subfamily.	Uncharacterized protein.	0.723
D910_01542	D910_10566	J3JX23	U4UT33	Protein transport protein SEC23; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules; Belongs to the SEC23/SEC24 family. SEC23 subfamily.	Uncharacterized protein.	0.997
D910_01563	D910_01759	N6UTD1	U4UT52	Uncharacterized protein.	DH domain-containing protein.	0.801
D910_01563	D910_01822	N6UTD1	U4UUS3	Uncharacterized protein.	DH domain-containing protein.	0.801
D910_01563	D910_03187	N6UTD1	U4TY80	Uncharacterized protein.	Uncharacterized protein.	0.769