STRINGSTRING
D910_05355 D910_05355 D910_04237 D910_04237 D910_04175 D910_04175 D910_05811 D910_05811 D910_09236 D910_09236 D910_06590 D910_06590 D910_08651 D910_08651 D910_10608 D910_10608 D910_12027 D910_12027 D910_00083 D910_00083 D910_05788 D910_05788
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
D910_05355Uncharacterized protein. (505 aa)
D910_04237Uncharacterized protein. (1043 aa)
D910_04175Uncharacterized protein. (1314 aa)
D910_05811ENTH domain-containing protein. (472 aa)
D910_09236FERM domain-containing protein. (136 aa)
D910_06590Hepatocyte growth factor-regulated tyrosine kinase substrate; Essential role in endosome membrane invagination and formation of multivesicular bodies, MVBs. Required during gastrulation and appears to regulate early embryonic signaling pathways. Inhibits tyrosine kinase receptor signaling by promoting degradation of the tyrosine-phosphorylated, active receptor, potentially by sorting activated receptors into MVBs. The MVBs are then trafficked to the lysosome where their contents are degraded. (659 aa)
D910_08651Uncharacterized protein. (915 aa)
D910_10608Cbl-PTB domain-containing protein. (181 aa)
D910_12027Uncharacterized protein. (427 aa)
D910_00083Uncharacterized protein. (239 aa)
D910_05788Uncharacterized protein. (211 aa)
Your Current Organism:
Dendroctonus ponderosae
NCBI taxonomy Id: 77166
Other names: D. ponderosae, mountain pine beetle
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