33 items (Dendroctonus ponderosae) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	D910_08150	Uncharacterized protein; Belongs to the small GTPase superfamily. Arf family. (193 aa)
	D910_07008	Uncharacterized protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (1328 aa)
	D910_05390	Uncharacterized protein. (250 aa)
	D910_05041	Arrestin_C domain-containing protein. (355 aa)
	D910_06590	Hepatocyte growth factor-regulated tyrosine kinase substrate; Essential role in endosome membrane invagination and formation of multivesicular bodies, MVBs. Required during gastrulation and appears to regulate early embryonic signaling pathways. Inhibits tyrosine kinase receptor signaling by promoting degradation of the tyrosine-phosphorylated, active receptor, potentially by sorting activated receptors into MVBs. The MVBs are then trafficked to the lysosome where their contents are degraded. (659 aa)
	D910_08573	Uncharacterized protein. (964 aa)
	D910_10401	Uncharacterized protein. (535 aa)
	D910_07638	Uncharacterized protein. (706 aa)
	D910_12066	Arrestin_C domain-containing protein. (252 aa)
	D910_12347	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1715 aa)
	D910_09505	Uncharacterized protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (786 aa)
	D910_12027	Uncharacterized protein. (427 aa)
	D910_00964	Uncharacterized protein; Belongs to the protein disulfide isomerase family. (384 aa)
	D910_02937	Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. (227 aa)
	D910_06682	Uncharacterized protein; Belongs to the synaptobrevin family. (220 aa)
	D910_05353	Sulfatase domain-containing protein. (688 aa)
	D910_05332	Uncharacterized protein; Belongs to the small GTPase superfamily. Arf family. (184 aa)
	D910_08046	Uncharacterized protein; Belongs to the small GTPase superfamily. Arf family. (180 aa)
	D910_06084	Arrestin_C domain-containing protein. (379 aa)
	D910_01975	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (157 aa)
	D910_11055	MHD domain-containing protein; Belongs to the adaptor complexes medium subunit family. (422 aa)
	D910_08690	Arrestin_C domain-containing protein. (430 aa)
	D910_00262	V-SNARE coiled-coil homology domain-containing protein. (95 aa)
	D910_09487	Thioredoxin domain-containing protein. (309 aa)
	D910_08063	CRAL-TRIO domain-containing protein. (336 aa)
	D910_02174	Uncharacterized protein. (1252 aa)
	D910_02993	Sulfatase domain-containing protein. (292 aa)
	D910_02173	Uncharacterized protein. (252 aa)
	D910_00856	Uncharacterized protein. (280 aa)
	D910_02176	Uncharacterized protein. (188 aa)
	D910_02175	Uncharacterized protein. (62 aa)
	D910_06730	Uncharacterized protein. (693 aa)
	D910_04042	AP-1 complex subunit gamma. (996 aa)

Your Current Organism:

Dendroctonus ponderosae

NCBI taxonomy Id: 77166
Other names: D. ponderosae, mountain pine beetle

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
D910_00262	D910_00856	N6T9N7	U4U0W1	V-SNARE coiled-coil homology domain-containing protein.	Uncharacterized protein.	0.457
D910_00262	D910_00964	N6T9N7	U4UU64	V-SNARE coiled-coil homology domain-containing protein.	Uncharacterized protein; Belongs to the protein disulfide isomerase family.	0.515
D910_00262	D910_01975	N6T9N7	J3JU90	V-SNARE coiled-coil homology domain-containing protein.	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	0.639
D910_00262	D910_02937	N6T9N7	U4TZQ8	V-SNARE coiled-coil homology domain-containing protein.	Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family.	0.784
D910_00262	D910_04042	N6T9N7	U4U9M5	V-SNARE coiled-coil homology domain-containing protein.	AP-1 complex subunit gamma.	0.755
D910_00262	D910_05332	N6T9N7	N6TKI6	V-SNARE coiled-coil homology domain-containing protein.	Uncharacterized protein; Belongs to the small GTPase superfamily. Arf family.	0.437
D910_00262	D910_05353	N6T9N7	N6TDL2	V-SNARE coiled-coil homology domain-containing protein.	Sulfatase domain-containing protein.	0.523
D910_00262	D910_06590	N6T9N7	U4UF40	V-SNARE coiled-coil homology domain-containing protein.	Hepatocyte growth factor-regulated tyrosine kinase substrate; Essential role in endosome membrane invagination and formation of multivesicular bodies, MVBs. Required during gastrulation and appears to regulate early embryonic signaling pathways. Inhibits tyrosine kinase receptor signaling by promoting degradation of the tyrosine-phosphorylated, active receptor, potentially by sorting activated receptors into MVBs. The MVBs are then trafficked to the lysosome where their contents are degraded.	0.660
D910_00262	D910_06682	N6T9N7	J3JY72	V-SNARE coiled-coil homology domain-containing protein.	Uncharacterized protein; Belongs to the synaptobrevin family.	0.746
D910_00262	D910_06730	N6T9N7	U4U669	V-SNARE coiled-coil homology domain-containing protein.	Uncharacterized protein.	0.452
D910_00262	D910_07008	N6T9N7	U4UBD3	V-SNARE coiled-coil homology domain-containing protein.	Uncharacterized protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	0.548
D910_00262	D910_07638	N6T9N7	U4UI51	V-SNARE coiled-coil homology domain-containing protein.	Uncharacterized protein.	0.719
D910_00262	D910_08046	N6T9N7	N6T7B4	V-SNARE coiled-coil homology domain-containing protein.	Uncharacterized protein; Belongs to the small GTPase superfamily. Arf family.	0.437
D910_00262	D910_08150	N6T9N7	U4UA39	V-SNARE coiled-coil homology domain-containing protein.	Uncharacterized protein; Belongs to the small GTPase superfamily. Arf family.	0.437
D910_00262	D910_09487	N6T9N7	N6TX51	V-SNARE coiled-coil homology domain-containing protein.	Thioredoxin domain-containing protein.	0.515
D910_00262	D910_09505	N6T9N7	U4UQ80	V-SNARE coiled-coil homology domain-containing protein.	Uncharacterized protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	0.548
D910_00262	D910_10401	N6T9N7	U4UGJ3	V-SNARE coiled-coil homology domain-containing protein.	Uncharacterized protein.	0.452
D910_00262	D910_11055	N6T9N7	J3JW23	V-SNARE coiled-coil homology domain-containing protein.	MHD domain-containing protein; Belongs to the adaptor complexes medium subunit family.	0.660
D910_00262	D910_12027	N6T9N7	U4UQF0	V-SNARE coiled-coil homology domain-containing protein.	Uncharacterized protein.	0.743
D910_00262	D910_12347	N6T9N7	U4UPP0	V-SNARE coiled-coil homology domain-containing protein.	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	0.743