132 items (Dendroctonus ponderosae) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	D910_06084	Arrestin_C domain-containing protein. (379 aa)
	D910_02086	PCI domain-containing protein. (417 aa)
	D910_05788	Uncharacterized protein. (211 aa)
	D910_01923	DUF1681 domain-containing protein. (243 aa)
	D910_11483	MPN domain-containing protein. (351 aa)
	D910_03001	MHD domain-containing protein; Belongs to the adaptor complexes medium subunit family. (438 aa)
	D910_06682	Uncharacterized protein; Belongs to the synaptobrevin family. (220 aa)
	D910_06695	Actin-related protein 2/3 complex subunit 3; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (177 aa)
	D910_09903	Actin-related protein 2/3 complex subunit; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (374 aa)
	D910_11639	Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament. (394 aa)
	D910_05172	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (409 aa)
	D910_04283	Uncharacterized protein. (238 aa)
	D910_06612	FH2 domain-containing protein. (773 aa)
	D910_07722	Uncharacterized protein; Belongs to the actin family. (376 aa)
	D910_02547	CSN8_PSD8_EIF3K domain-containing protein. (186 aa)
	D910_00262	V-SNARE coiled-coil homology domain-containing protein. (95 aa)
	D910_07061	Uncharacterized protein. (952 aa)
	D910_08938	Uncharacterized protein; Belongs to the actin family. (376 aa)
	D910_12078	PCI domain-containing protein. (442 aa)
	D910_01925	PCI domain-containing protein. (269 aa)
	D910_07034	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (257 aa)
	D910_09899	Uncharacterized protein. (544 aa)
	D910_05727	G_PROTEIN_RECEP_F1_2 domain-containing protein. (335 aa)
	D910_08690	Arrestin_C domain-containing protein. (430 aa)
	D910_05592	PCI domain-containing protein. (429 aa)
	D910_11552	Alpha_adaptinC2 domain-containing protein. (937 aa)
	D910_12794	MHD domain-containing protein. (907 aa)
	D910_07635	Uncharacterized protein. (168 aa)
	D910_05811	ENTH domain-containing protein. (472 aa)
	D910_11803	Uncharacterized protein. (1178 aa)
	D910_07882	Ubiquitin-like domain-containing protein. (356 aa)
	D910_06403	Rho-GAP domain-containing protein. (688 aa)
	D910_01405	Uncharacterized protein; Belongs to the actin family. (419 aa)
	D910_02397	PCI domain-containing protein. (434 aa)
	D910_02645	Uncharacterized protein. (60 aa)
	D910_02903	C-type lectin domain-containing protein. (210 aa)
	D910_01342	ABC transmembrane type-1 domain-containing protein. (298 aa)
	D910_02266	ABC transmembrane type-1 domain-containing protein. (428 aa)
	D910_02120	MRP-S23 domain-containing protein. (471 aa)
	D910_03006	MFS domain-containing protein. (418 aa)
	D910_04237	Uncharacterized protein. (1043 aa)
	D910_00660	MFS domain-containing protein. (153 aa)
	D910_02872	PX domain-containing protein; Belongs to the tetraspanin (TM4SF) family. (682 aa)
	D910_02937	Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. (227 aa)
	D910_00930	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (334 aa)
	D910_03382	ANK_REP_REGION domain-containing protein. (1268 aa)
	D910_04285	F-BAR domain-containing protein. (401 aa)
	D910_04360	MPN domain-containing protein. (317 aa)
	D910_01322	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (368 aa)
	D910_02265	Uncharacterized protein. (346 aa)
	D910_02264	ABC transmembrane type-1 domain-containing protein. (347 aa)
	D910_05355	Uncharacterized protein. (505 aa)
	D910_05674	KxDL domain-containing protein. (164 aa)
	D910_02646	SAC domain-containing protein. (986 aa)
	D910_02721	Uncharacterized protein. (580 aa)
	D910_06730	Uncharacterized protein. (693 aa)
	D910_06801	ENTH domain-containing protein. (475 aa)
	D910_05281	Uncharacterized protein. (371 aa)
	D910_06204	Uncharacterized protein. (555 aa)
	D910_05521	Uncharacterized protein. (192 aa)
	D910_06229	Uncharacterized protein. (1135 aa)
	D910_07283	Uncharacterized protein. (155 aa)
	D910_06799	ANTH domain-containing protein. (189 aa)
	D910_06195	Uncharacterized protein. (734 aa)
	D910_03914	Uncharacterized protein. (1477 aa)
	D910_07035	Uncharacterized protein. (128 aa)
	D910_07941	I/LWEQ domain-containing protein. (913 aa)
	D910_06800	PCI domain-containing protein. (208 aa)
	D910_07008	Uncharacterized protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (1328 aa)
	D910_08651	Uncharacterized protein. (915 aa)
	D910_07114	Uncharacterized protein. (1235 aa)
	D910_05579	Uncharacterized protein. (1655 aa)
	D910_05041	Arrestin_C domain-containing protein. (355 aa)
	D910_07562	Uncharacterized protein; Belongs to the type-B carboxylesterase/lipase family. (5427 aa)
	D910_08309	Uncharacterized protein. (488 aa)
	D910_05363	Uncharacterized protein. (2626 aa)
	D910_07757	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (154 aa)
	D910_08568	Uncharacterized protein. (546 aa)
	D910_06203	Uncharacterized protein. (301 aa)
	D910_06512	Uncharacterized protein. (2477 aa)
	D910_05836	Uncharacterized protein. (1623 aa)
	D910_05841	Uncharacterized protein; Belongs to the actin family. (837 aa)
	D910_09897	Protein kinase domain-containing protein. (552 aa)
	D910_08275	PCI domain-containing protein. (752 aa)
	D910_06590	Hepatocyte growth factor-regulated tyrosine kinase substrate; Essential role in endosome membrane invagination and formation of multivesicular bodies, MVBs. Required during gastrulation and appears to regulate early embryonic signaling pathways. Inhibits tyrosine kinase receptor signaling by promoting degradation of the tyrosine-phosphorylated, active receptor, potentially by sorting activated receptors into MVBs. The MVBs are then trafficked to the lysosome where their contents are degraded. (659 aa)
	D910_06693	Uncharacterized protein; Belongs to the Stoned B family. (1120 aa)
	D910_06761	Uncharacterized protein. (295 aa)
	D910_10401	Uncharacterized protein. (535 aa)
	D910_10608	Cbl-PTB domain-containing protein. (181 aa)
	D910_10862	Uncharacterized protein. (745 aa)
	D910_07638	Uncharacterized protein. (706 aa)
	D910_10061	Uncharacterized protein. (293 aa)
	D910_10865	ABC transmembrane type-1 domain-containing protein. (157 aa)
	D910_10233	Uncharacterized protein. (779 aa)
	D910_10915	ABC transporter domain-containing protein. (214 aa)
	D910_12018	Uncharacterized protein. (258 aa)
	D910_08221	Uncharacterized protein. (1385 aa)
	D910_10852	Uncharacterized protein. (1346 aa)
	D910_10916	ABC transmembrane type-1 domain-containing protein. (264 aa)
	D910_00202	Uncharacterized protein. (537 aa)
	D910_12066	Arrestin_C domain-containing protein. (252 aa)
	D910_09358	Uncharacterized protein. (519 aa)
	D910_12347	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1715 aa)
	D910_09505	Uncharacterized protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (786 aa)
	D910_09562	Uncharacterized protein. (2498 aa)
	D910_12017	Vitellogenin domain-containing protein. (1214 aa)
	D910_12027	Uncharacterized protein. (427 aa)
	D910_12803	VWFD domain-containing protein. (732 aa)
	D910_10031	ABC transporter domain-containing protein. (648 aa)
	D910_00317	Uncharacterized protein. (50 aa)
	D910_10113	Uncharacterized protein. (1258 aa)
	D910_10313	Uncharacterized protein. (97 aa)
	D910_12720	Uncharacterized protein. (3302 aa)
	D910_01174	Uncharacterized protein. (187 aa)
	D910_10532	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (519 aa)
	D910_00083	Uncharacterized protein. (239 aa)
	D910_00169	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (337 aa)
	D910_10770	Uncharacterized protein. (1253 aa)
	D910_10864	Uncharacterized protein. (1094 aa)
	D910_00578	ABC transporter domain-containing protein. (183 aa)
	D910_10863	ABC transmembrane type-1 domain-containing protein. (345 aa)
	D910_10914	Uncharacterized protein. (431 aa)
	D910_10913	ABC transmembrane type-1 domain-containing protein. (374 aa)
	D910_10973	Uncharacterized protein. (363 aa)
	D910_11699	Uncharacterized protein. (1269 aa)
	D910_11708	Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (2794 aa)
	D910_12020	Uncharacterized protein. (358 aa)
	D910_12783	ENTH domain-containing protein. (600 aa)
	D910_12802	Vitellogenin domain-containing protein. (741 aa)
	D910_12801	Uncharacterized protein. (1772 aa)
	D910_00721	WH1 domain-containing protein. (105 aa)
	D910_00906	ABC transmembrane type-1 domain-containing protein. (410 aa)

Your Current Organism:

Dendroctonus ponderosae

NCBI taxonomy Id: 77166
Other names: D. ponderosae, mountain pine beetle

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
D910_00083	D910_02721	U4UT05	U4U5R2	Uncharacterized protein.	Uncharacterized protein.	0.445
D910_00083	D910_03001	U4UT05	J3JY16	Uncharacterized protein.	MHD domain-containing protein; Belongs to the adaptor complexes medium subunit family.	0.607
D910_00083	D910_04237	U4UT05	U4TZ20	Uncharacterized protein.	Uncharacterized protein.	0.963
D910_00083	D910_05281	U4UT05	U4U6F5	Uncharacterized protein.	Uncharacterized protein.	0.445
D910_00083	D910_05788	U4UT05	J3JVP3	Uncharacterized protein.	Uncharacterized protein.	0.957
D910_00083	D910_05811	U4UT05	N6UGB8	Uncharacterized protein.	ENTH domain-containing protein.	0.612
D910_00083	D910_06590	U4UT05	U4UF40	Uncharacterized protein.	Hepatocyte growth factor-regulated tyrosine kinase substrate; Essential role in endosome membrane invagination and formation of multivesicular bodies, MVBs. Required during gastrulation and appears to regulate early embryonic signaling pathways. Inhibits tyrosine kinase receptor signaling by promoting degradation of the tyrosine-phosphorylated, active receptor, potentially by sorting activated receptors into MVBs. The MVBs are then trafficked to the lysosome where their contents are degraded.	0.595
D910_00083	D910_07882	U4UT05	N6UJK5	Uncharacterized protein.	Ubiquitin-like domain-containing protein.	0.417
D910_00083	D910_08651	U4UT05	U4UBL1	Uncharacterized protein.	Uncharacterized protein.	0.659
D910_00083	D910_10608	U4UT05	U4UH44	Uncharacterized protein.	Cbl-PTB domain-containing protein.	0.929
D910_00083	D910_12027	U4UT05	U4UQF0	Uncharacterized protein.	Uncharacterized protein.	0.591
D910_00083	D910_12347	U4UT05	U4UPP0	Uncharacterized protein.	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	0.573
D910_00202	D910_00906	U4UNT2	U4V049	Uncharacterized protein.	ABC transmembrane type-1 domain-containing protein.	0.807
D910_00202	D910_10863	U4UNT2	U4UTU6	Uncharacterized protein.	ABC transmembrane type-1 domain-containing protein.	0.799
D910_00202	D910_10914	U4UNT2	U4UTV4	Uncharacterized protein.	Uncharacterized protein.	0.896
D910_00202	D910_10915	U4UNT2	U4UKI2	Uncharacterized protein.	ABC transporter domain-containing protein.	0.934
D910_00202	D910_10916	U4UNT2	U4UMB5	Uncharacterized protein.	ABC transmembrane type-1 domain-containing protein.	0.534
D910_00262	D910_00660	N6T9N7	U4TZ37	V-SNARE coiled-coil homology domain-containing protein.	MFS domain-containing protein.	0.627
D910_00262	D910_01923	N6T9N7	J3JWK0	V-SNARE coiled-coil homology domain-containing protein.	DUF1681 domain-containing protein.	0.715
D910_00262	D910_02721	N6T9N7	U4U5R2	V-SNARE coiled-coil homology domain-containing protein.	Uncharacterized protein.	0.502