85 items (Dendroctonus ponderosae) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	D910_00731	Runt domain-containing protein. (133 aa)
	D910_00897	Runt domain-containing protein. (122 aa)
	D910_01240	DUF2236 domain-containing protein. (390 aa)
	D910_02839	Uncharacterized protein. (253 aa)
	D910_02172	SHSP domain-containing protein; Belongs to the small heat shock protein (HSP20) family. (231 aa)
	D910_00956	Cyclin N-terminal domain-containing protein. (727 aa)
	D910_11557	Uncharacterized protein. (840 aa)
	D910_10407	Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (539 aa)
	D910_10363	BHLH domain-containing protein. (256 aa)
	D910_09411	Fork-head domain-containing protein. (155 aa)
	D910_09412	FOXO-TAD domain-containing protein. (334 aa)
	D910_11239	Peptidylprolyl isomerase. (291 aa)
	D910_11714	Uncharacterized protein; Belongs to the DEAD box helicase family. (522 aa)
	D910_11558	Uncharacterized protein. (122 aa)
	D910_11464	Uncharacterized protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (566 aa)
	D910_08047	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (204 aa)
	D910_08083	Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (290 aa)
	D910_07661	Uncharacterized protein. (120 aa)
	D910_10592	Uncharacterized protein; Belongs to the DEAD box helicase family. (568 aa)
	D910_09931	TPR_REGION domain-containing protein. (758 aa)
	D910_10441	Uncharacterized protein. (895 aa)
	D910_02333	Uncharacterized protein. (201 aa)
	D910_10131	General transcription factor IIF subunit 2; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. This subunit shows ATP-dependent DNA-helicase activity. (265 aa)
	D910_09620	DUF2236 domain-containing protein. (331 aa)
	D910_06960	Uncharacterized protein. (162 aa)
	D910_10867	Uncharacterized protein. (777 aa)
	D910_06648	Uncharacterized protein. (447 aa)
	D910_06554	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (379 aa)
	D910_00675	Protein kinase domain-containing protein. (257 aa)
	D910_06956	Uncharacterized protein. (361 aa)
	D910_06703	WD_REPEATS_REGION domain-containing protein. (696 aa)
	D910_05980	Uncharacterized protein. (108 aa)
	D910_08857	CS domain-containing protein. (163 aa)
	D910_09728	Uncharacterized protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (415 aa)
	D910_06163	CYCLIN domain-containing protein; Belongs to the cyclin family. (1227 aa)
	D910_01209	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1429 aa)
	D910_03977	Uncharacterized protein. (1871 aa)
	D910_06591	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1449 aa)
	D910_07194	Importin N-terminal domain-containing protein. (1148 aa)
	D910_03978	Uncharacterized protein. (290 aa)
	D910_06553	Phorbol-ester/DAG-type domain-containing protein. (182 aa)
	D910_04895	PPP5 domain-containing protein. (169 aa)
	D910_02542	Uncharacterized protein. (781 aa)
	D910_03088	Runt domain-containing protein. (485 aa)
	D910_03063	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1871 aa)
	D910_06231	RNA_pol_L_2 domain-containing protein. (72 aa)
	D910_02117	Runt domain-containing protein. (349 aa)
	D910_05979	Uncharacterized protein. (135 aa)
	D910_05107	Uncharacterized protein. (428 aa)
	D910_04668	Uncharacterized protein. (202 aa)
	D910_01032	Uncharacterized protein. (148 aa)
	D910_06732	Uncharacterized protein. (318 aa)
	D910_01956	Transcription initiation factor IIA subunit 2; TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation; Belongs to the TFIIA subunit 2 family. (106 aa)
	D910_09068	Uncharacterized protein. (210 aa)
	D910_00307	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (130 aa)
	D910_08874	HATPase_c domain-containing protein. (709 aa)
	D910_06473	Uncharacterized protein. (131 aa)
	D910_11839	Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (103 aa)
	D910_09826	RPOLD domain-containing protein. (275 aa)
	D910_03408	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (486 aa)
	D910_08311	Uncharacterized protein. (209 aa)
	D910_04274	Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family. (506 aa)
	D910_05801	C-type lectin domain-containing protein. (154 aa)
	D910_03629	CXXC-type domain-containing protein. (470 aa)
	D910_02639	Uncharacterized protein. (450 aa)
	D910_06888	Uncharacterized protein. (970 aa)
	D910_06886	Uncharacterized protein; Belongs to the DEAD box helicase family. (775 aa)
	D910_03171	Uncharacterized protein. (59 aa)
	D910_08273	Uncharacterized protein. (116 aa)
	D910_06887	Uncharacterized protein; Belongs to the DEAD box helicase family. (560 aa)
	D910_11518	Uncharacterized protein. (405 aa)
	D910_10931	Uncharacterized protein; Belongs to the DEAD box helicase family. (777 aa)
	D910_02732	Uncharacterized protein. (301 aa)
	D910_04444	Uncharacterized protein. (193 aa)
	D910_06191	Uncharacterized protein. (257 aa)
	D910_03089	Runt domain-containing protein. (506 aa)
	D910_03595	ANK_REP_REGION domain-containing protein. (948 aa)
	D910_04237	Uncharacterized protein. (1043 aa)
	D910_00378	Uncharacterized protein. (107 aa)
	D910_00270	Uncharacterized protein. (326 aa)
	D910_02271	SHS2_Rpb7-N domain-containing protein. (94 aa)
	D910_07662	Uncharacterized protein. (88 aa)
	D910_11025	Fork-head domain-containing protein. (436 aa)
	D910_01503	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (152 aa)
	D910_01211	Uncharacterized protein. (333 aa)

Your Current Organism:

Dendroctonus ponderosae

NCBI taxonomy Id: 77166
Other names: D. ponderosae, mountain pine beetle

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
D910_00307	D910_00378	J3JUM6	U4TYP9	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.	Uncharacterized protein.	0.864
D910_00307	D910_00956	J3JUM6	U4V0A7	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.	Cyclin N-terminal domain-containing protein.	0.596
D910_00307	D910_01209	J3JUM6	U4UBL6	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.999
D910_00307	D910_01211	J3JUM6	U4TR42	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.	Uncharacterized protein.	0.893
D910_00307	D910_01240	J3JUM6	U4TT73	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.	DUF2236 domain-containing protein.	0.930
D910_00307	D910_01956	J3JUM6	J3JUB6	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.	Transcription initiation factor IIA subunit 2; TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation; Belongs to the TFIIA subunit 2 family.	0.968
D910_00307	D910_02271	J3JUM6	U4TVQ3	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.	SHS2_Rpb7-N domain-containing protein.	0.999
D910_00307	D910_02732	J3JUM6	N6U3Q4	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.	Uncharacterized protein.	0.864
D910_00307	D910_03063	J3JUM6	U4U4W4	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.999
D910_00307	D910_03171	J3JUM6	N6TSR1	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.	Uncharacterized protein.	0.999
D910_00307	D910_04274	J3JUM6	N6T4W4	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.	Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family.	0.996
D910_00307	D910_06163	J3JUM6	U4UDW2	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.	CYCLIN domain-containing protein; Belongs to the cyclin family.	0.596
D910_00307	D910_06231	J3JUM6	U4U4Q0	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.	RNA_pol_L_2 domain-containing protein.	0.999
D910_00307	D910_06473	J3JUM6	J3JU72	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.	Uncharacterized protein.	0.999
D910_00307	D910_06591	J3JUM6	U4U837	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	0.719
D910_00307	D910_06732	J3JUM6	J3JVZ2	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.	Uncharacterized protein.	0.919
D910_00307	D910_08047	J3JUM6	U4UL10	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.679
D910_00307	D910_08273	J3JUM6	N6TU50	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.	Uncharacterized protein.	0.999
D910_00307	D910_08311	J3JUM6	N6T0V3	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.	Uncharacterized protein.	0.919
D910_00307	D910_09068	J3JUM6	J3JUD2	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.	Uncharacterized protein.	0.999