22 items (Dendroctonus ponderosae) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	D910_01859	Uncharacterized protein. (739 aa)
	D910_02901	Uncharacterized protein. (160 aa)
	D910_09336	t-SNARE coiled-coil homology domain-containing protein; Belongs to the syntaxin family. (716 aa)
	D910_07906	Aldedh domain-containing protein. (258 aa)
	D910_06570	Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (489 aa)
	D910_06736	ATPase ASNA1 homolog; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for ins [...] (328 aa)
	D910_12344	Uncharacterized protein. (200 aa)
	D910_12342	Uncharacterized protein. (697 aa)
	D910_10408	Uncharacterized protein. (68 aa)
	D910_02600	TPR_REGION domain-containing protein. (316 aa)
	D910_10457	Uncharacterized protein. (95 aa)
	D910_04766	Uncharacterized protein. (64 aa)
	D910_00262	V-SNARE coiled-coil homology domain-containing protein. (95 aa)
	D910_03129	UBIQUITIN_CONJUGAT_2 domain-containing protein. (228 aa)
	D910_12393	Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (498 aa)
	D910_12397	Ubiquitin-like domain-containing protein. (129 aa)
	cytb5	Cytochrome b5; Belongs to the cytochrome b5 family. (129 aa)
	D910_07905	Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (533 aa)
	D910_07907	Aldedh domain-containing protein. (306 aa)
	D910_03679	Uncharacterized protein. (107 aa)
	D910_07184	t-SNARE coiled-coil homology domain-containing protein. (287 aa)
	D910_03680	t-SNARE coiled-coil homology domain-containing protein. (64 aa)

Your Current Organism:

Dendroctonus ponderosae

NCBI taxonomy Id: 77166
Other names: D. ponderosae, mountain pine beetle

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
D910_00262	D910_02600	N6T9N7	N6UH83	V-SNARE coiled-coil homology domain-containing protein.	TPR_REGION domain-containing protein.	0.643
D910_00262	D910_03679	N6T9N7	U4U8J6	V-SNARE coiled-coil homology domain-containing protein.	Uncharacterized protein.	0.923
D910_00262	D910_03680	N6T9N7	U4U6N1	V-SNARE coiled-coil homology domain-containing protein.	t-SNARE coiled-coil homology domain-containing protein.	0.923
D910_00262	D910_06736	N6T9N7	U4UHL6	V-SNARE coiled-coil homology domain-containing protein.	ATPase ASNA1 homolog; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for ins [...]	0.412
D910_00262	D910_07184	N6T9N7	U4U7F9	V-SNARE coiled-coil homology domain-containing protein.	t-SNARE coiled-coil homology domain-containing protein.	0.992
D910_00262	D910_09336	N6T9N7	U4UDG3	V-SNARE coiled-coil homology domain-containing protein.	t-SNARE coiled-coil homology domain-containing protein; Belongs to the syntaxin family.	0.975
D910_00262	D910_12397	N6T9N7	J3JTE2	V-SNARE coiled-coil homology domain-containing protein.	Ubiquitin-like domain-containing protein.	0.408
D910_01859	D910_02600	U4U1F5	N6UH83	Uncharacterized protein.	TPR_REGION domain-containing protein.	0.964
D910_01859	D910_02901	U4U1F5	U4TXG0	Uncharacterized protein.	Uncharacterized protein.	0.764
D910_01859	D910_06736	U4U1F5	U4UHL6	Uncharacterized protein.	ATPase ASNA1 homolog; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for ins [...]	0.993
D910_01859	D910_10457	U4U1F5	N6U6M1	Uncharacterized protein.	Uncharacterized protein.	0.619
D910_01859	D910_12342	U4U1F5	U4UPN4	Uncharacterized protein.	Uncharacterized protein.	0.937
D910_01859	D910_12344	U4U1F5	U4ULX2	Uncharacterized protein.	Uncharacterized protein.	0.937
D910_01859	D910_12397	U4U1F5	J3JTE2	Uncharacterized protein.	Ubiquitin-like domain-containing protein.	0.883
D910_02600	D910_00262	N6UH83	N6T9N7	TPR_REGION domain-containing protein.	V-SNARE coiled-coil homology domain-containing protein.	0.643
D910_02600	D910_01859	N6UH83	U4U1F5	TPR_REGION domain-containing protein.	Uncharacterized protein.	0.964
D910_02600	D910_02901	N6UH83	U4TXG0	TPR_REGION domain-containing protein.	Uncharacterized protein.	0.761
D910_02600	D910_04766	N6UH83	N6TWI7	TPR_REGION domain-containing protein.	Uncharacterized protein.	0.651
D910_02600	D910_06736	N6UH83	U4UHL6	TPR_REGION domain-containing protein.	ATPase ASNA1 homolog; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for ins [...]	0.924
D910_02600	D910_09336	N6UH83	U4UDG3	TPR_REGION domain-containing protein.	t-SNARE coiled-coil homology domain-containing protein; Belongs to the syntaxin family.	0.744