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SMAC_00084 | WGS project CABT00000000 data, contig 2.1. (233 aa) | ||||
ATG3 | Autophagy-related protein 3; E2 conjugating enzyme required for the cytoplasm to vacuole transport (Cvt) and autophagy (By similarity). Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production (By similarity). Responsible for the E2-like covalent binding of phosphatidylethanolamine to the C-terminal Gly of ATG8 (By similarity). The ATG12-ATG5 conjugate pla [...] (346 aa) | ||||
SMAC_08343 | Autophagy protein 5; Involved in cytoplasm to vacuole transport (Cvt) and autophagic vesicle formation. (366 aa) | ||||
ATG7 | Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 and ATG8 for its conjugation with phosphatidylethanolamine (By similarity). Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes (By similarity). Autophagy is essential for maintenance of amino acid levels and protein synthesis under nitrogen starvation. Required for selective autophagic degradation of the nucleus (nucleoph [...] (699 aa) | ||||
ATG12 | Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in cytoplasm to vacuole transport (Cvt), autophagy vesicles formation, mitophagy, and nucleophagy (By similarity). Conjugation with ATG5 through a ubiquitin- like conjugating system involving also ATG7 as an E1-like activating enzyme and ATG10 as an E2-like conjugating enzyme, is essential for its function (By similarity). The ATG12-ATG5 conjugate acts as an E3-like enzyme which is required for lipidation of ATG8 and ATG8 association to the vesicle membranes. ATG12-ATG5 rearranges the ATG3 catalytic center and enhances its E [...] (159 aa) |
node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ATG12 | ATG3 | F7W503 | F7VSU2 | Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in cytoplasm to vacuole transport (Cvt), autophagy vesicles formation, mitophagy, and nucleophagy (By similarity). Conjugation with ATG5 through a ubiquitin- like conjugating system involving also ATG7 as an E1-like activating enzyme and ATG10 as an E2-like conjugating enzyme, is essential for its function (By similarity). The ATG12-ATG5 conjugate acts as an E3-like enzyme which is required for lipidation of ATG8 and ATG8 association to the vesicle membranes. ATG12-ATG5 rearranges the ATG3 catalytic center and enhances its E [...] | Autophagy-related protein 3; E2 conjugating enzyme required for the cytoplasm to vacuole transport (Cvt) and autophagy (By similarity). Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production (By similarity). Responsible for the E2-like covalent binding of phosphatidylethanolamine to the C-terminal Gly of ATG8 (By similarity). The ATG12-ATG5 conjugate pla [...] | 0.999 |
ATG12 | ATG7 | F7W503 | F7W4M2 | Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in cytoplasm to vacuole transport (Cvt), autophagy vesicles formation, mitophagy, and nucleophagy (By similarity). Conjugation with ATG5 through a ubiquitin- like conjugating system involving also ATG7 as an E1-like activating enzyme and ATG10 as an E2-like conjugating enzyme, is essential for its function (By similarity). The ATG12-ATG5 conjugate acts as an E3-like enzyme which is required for lipidation of ATG8 and ATG8 association to the vesicle membranes. ATG12-ATG5 rearranges the ATG3 catalytic center and enhances its E [...] | Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 and ATG8 for its conjugation with phosphatidylethanolamine (By similarity). Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes (By similarity). Autophagy is essential for maintenance of amino acid levels and protein synthesis under nitrogen starvation. Required for selective autophagic degradation of the nucleus (nucleoph [...] | 0.999 |
ATG12 | SMAC_00084 | F7W503 | F7VK41 | Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in cytoplasm to vacuole transport (Cvt), autophagy vesicles formation, mitophagy, and nucleophagy (By similarity). Conjugation with ATG5 through a ubiquitin- like conjugating system involving also ATG7 as an E1-like activating enzyme and ATG10 as an E2-like conjugating enzyme, is essential for its function (By similarity). The ATG12-ATG5 conjugate acts as an E3-like enzyme which is required for lipidation of ATG8 and ATG8 association to the vesicle membranes. ATG12-ATG5 rearranges the ATG3 catalytic center and enhances its E [...] | WGS project CABT00000000 data, contig 2.1. | 0.966 |
ATG12 | SMAC_08343 | F7W503 | F7VTL8 | Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in cytoplasm to vacuole transport (Cvt), autophagy vesicles formation, mitophagy, and nucleophagy (By similarity). Conjugation with ATG5 through a ubiquitin- like conjugating system involving also ATG7 as an E1-like activating enzyme and ATG10 as an E2-like conjugating enzyme, is essential for its function (By similarity). The ATG12-ATG5 conjugate acts as an E3-like enzyme which is required for lipidation of ATG8 and ATG8 association to the vesicle membranes. ATG12-ATG5 rearranges the ATG3 catalytic center and enhances its E [...] | Autophagy protein 5; Involved in cytoplasm to vacuole transport (Cvt) and autophagic vesicle formation. | 0.999 |
ATG3 | ATG12 | F7VSU2 | F7W503 | Autophagy-related protein 3; E2 conjugating enzyme required for the cytoplasm to vacuole transport (Cvt) and autophagy (By similarity). Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production (By similarity). Responsible for the E2-like covalent binding of phosphatidylethanolamine to the C-terminal Gly of ATG8 (By similarity). The ATG12-ATG5 conjugate pla [...] | Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in cytoplasm to vacuole transport (Cvt), autophagy vesicles formation, mitophagy, and nucleophagy (By similarity). Conjugation with ATG5 through a ubiquitin- like conjugating system involving also ATG7 as an E1-like activating enzyme and ATG10 as an E2-like conjugating enzyme, is essential for its function (By similarity). The ATG12-ATG5 conjugate acts as an E3-like enzyme which is required for lipidation of ATG8 and ATG8 association to the vesicle membranes. ATG12-ATG5 rearranges the ATG3 catalytic center and enhances its E [...] | 0.999 |
ATG3 | ATG7 | F7VSU2 | F7W4M2 | Autophagy-related protein 3; E2 conjugating enzyme required for the cytoplasm to vacuole transport (Cvt) and autophagy (By similarity). Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production (By similarity). Responsible for the E2-like covalent binding of phosphatidylethanolamine to the C-terminal Gly of ATG8 (By similarity). The ATG12-ATG5 conjugate pla [...] | Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 and ATG8 for its conjugation with phosphatidylethanolamine (By similarity). Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes (By similarity). Autophagy is essential for maintenance of amino acid levels and protein synthesis under nitrogen starvation. Required for selective autophagic degradation of the nucleus (nucleoph [...] | 0.999 |
ATG3 | SMAC_00084 | F7VSU2 | F7VK41 | Autophagy-related protein 3; E2 conjugating enzyme required for the cytoplasm to vacuole transport (Cvt) and autophagy (By similarity). Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production (By similarity). Responsible for the E2-like covalent binding of phosphatidylethanolamine to the C-terminal Gly of ATG8 (By similarity). The ATG12-ATG5 conjugate pla [...] | WGS project CABT00000000 data, contig 2.1. | 0.926 |
ATG3 | SMAC_08343 | F7VSU2 | F7VTL8 | Autophagy-related protein 3; E2 conjugating enzyme required for the cytoplasm to vacuole transport (Cvt) and autophagy (By similarity). Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production (By similarity). Responsible for the E2-like covalent binding of phosphatidylethanolamine to the C-terminal Gly of ATG8 (By similarity). The ATG12-ATG5 conjugate pla [...] | Autophagy protein 5; Involved in cytoplasm to vacuole transport (Cvt) and autophagic vesicle formation. | 0.999 |
ATG7 | ATG12 | F7W4M2 | F7W503 | Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 and ATG8 for its conjugation with phosphatidylethanolamine (By similarity). Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes (By similarity). Autophagy is essential for maintenance of amino acid levels and protein synthesis under nitrogen starvation. Required for selective autophagic degradation of the nucleus (nucleoph [...] | Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in cytoplasm to vacuole transport (Cvt), autophagy vesicles formation, mitophagy, and nucleophagy (By similarity). Conjugation with ATG5 through a ubiquitin- like conjugating system involving also ATG7 as an E1-like activating enzyme and ATG10 as an E2-like conjugating enzyme, is essential for its function (By similarity). The ATG12-ATG5 conjugate acts as an E3-like enzyme which is required for lipidation of ATG8 and ATG8 association to the vesicle membranes. ATG12-ATG5 rearranges the ATG3 catalytic center and enhances its E [...] | 0.999 |
ATG7 | ATG3 | F7W4M2 | F7VSU2 | Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 and ATG8 for its conjugation with phosphatidylethanolamine (By similarity). Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes (By similarity). Autophagy is essential for maintenance of amino acid levels and protein synthesis under nitrogen starvation. Required for selective autophagic degradation of the nucleus (nucleoph [...] | Autophagy-related protein 3; E2 conjugating enzyme required for the cytoplasm to vacuole transport (Cvt) and autophagy (By similarity). Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production (By similarity). Responsible for the E2-like covalent binding of phosphatidylethanolamine to the C-terminal Gly of ATG8 (By similarity). The ATG12-ATG5 conjugate pla [...] | 0.999 |
ATG7 | SMAC_00084 | F7W4M2 | F7VK41 | Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 and ATG8 for its conjugation with phosphatidylethanolamine (By similarity). Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes (By similarity). Autophagy is essential for maintenance of amino acid levels and protein synthesis under nitrogen starvation. Required for selective autophagic degradation of the nucleus (nucleoph [...] | WGS project CABT00000000 data, contig 2.1. | 0.772 |
ATG7 | SMAC_08343 | F7W4M2 | F7VTL8 | Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 and ATG8 for its conjugation with phosphatidylethanolamine (By similarity). Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes (By similarity). Autophagy is essential for maintenance of amino acid levels and protein synthesis under nitrogen starvation. Required for selective autophagic degradation of the nucleus (nucleoph [...] | Autophagy protein 5; Involved in cytoplasm to vacuole transport (Cvt) and autophagic vesicle formation. | 0.955 |
SMAC_00084 | ATG12 | F7VK41 | F7W503 | WGS project CABT00000000 data, contig 2.1. | Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in cytoplasm to vacuole transport (Cvt), autophagy vesicles formation, mitophagy, and nucleophagy (By similarity). Conjugation with ATG5 through a ubiquitin- like conjugating system involving also ATG7 as an E1-like activating enzyme and ATG10 as an E2-like conjugating enzyme, is essential for its function (By similarity). The ATG12-ATG5 conjugate acts as an E3-like enzyme which is required for lipidation of ATG8 and ATG8 association to the vesicle membranes. ATG12-ATG5 rearranges the ATG3 catalytic center and enhances its E [...] | 0.966 |
SMAC_00084 | ATG3 | F7VK41 | F7VSU2 | WGS project CABT00000000 data, contig 2.1. | Autophagy-related protein 3; E2 conjugating enzyme required for the cytoplasm to vacuole transport (Cvt) and autophagy (By similarity). Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production (By similarity). Responsible for the E2-like covalent binding of phosphatidylethanolamine to the C-terminal Gly of ATG8 (By similarity). The ATG12-ATG5 conjugate pla [...] | 0.926 |
SMAC_00084 | ATG7 | F7VK41 | F7W4M2 | WGS project CABT00000000 data, contig 2.1. | Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 and ATG8 for its conjugation with phosphatidylethanolamine (By similarity). Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes (By similarity). Autophagy is essential for maintenance of amino acid levels and protein synthesis under nitrogen starvation. Required for selective autophagic degradation of the nucleus (nucleoph [...] | 0.772 |
SMAC_00084 | SMAC_08343 | F7VK41 | F7VTL8 | WGS project CABT00000000 data, contig 2.1. | Autophagy protein 5; Involved in cytoplasm to vacuole transport (Cvt) and autophagic vesicle formation. | 0.902 |
SMAC_08343 | ATG12 | F7VTL8 | F7W503 | Autophagy protein 5; Involved in cytoplasm to vacuole transport (Cvt) and autophagic vesicle formation. | Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in cytoplasm to vacuole transport (Cvt), autophagy vesicles formation, mitophagy, and nucleophagy (By similarity). Conjugation with ATG5 through a ubiquitin- like conjugating system involving also ATG7 as an E1-like activating enzyme and ATG10 as an E2-like conjugating enzyme, is essential for its function (By similarity). The ATG12-ATG5 conjugate acts as an E3-like enzyme which is required for lipidation of ATG8 and ATG8 association to the vesicle membranes. ATG12-ATG5 rearranges the ATG3 catalytic center and enhances its E [...] | 0.999 |
SMAC_08343 | ATG3 | F7VTL8 | F7VSU2 | Autophagy protein 5; Involved in cytoplasm to vacuole transport (Cvt) and autophagic vesicle formation. | Autophagy-related protein 3; E2 conjugating enzyme required for the cytoplasm to vacuole transport (Cvt) and autophagy (By similarity). Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production (By similarity). Responsible for the E2-like covalent binding of phosphatidylethanolamine to the C-terminal Gly of ATG8 (By similarity). The ATG12-ATG5 conjugate pla [...] | 0.999 |
SMAC_08343 | ATG7 | F7VTL8 | F7W4M2 | Autophagy protein 5; Involved in cytoplasm to vacuole transport (Cvt) and autophagic vesicle formation. | Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 and ATG8 for its conjugation with phosphatidylethanolamine (By similarity). Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes (By similarity). Autophagy is essential for maintenance of amino acid levels and protein synthesis under nitrogen starvation. Required for selective autophagic degradation of the nucleus (nucleoph [...] | 0.955 |
SMAC_08343 | SMAC_00084 | F7VTL8 | F7VK41 | Autophagy protein 5; Involved in cytoplasm to vacuole transport (Cvt) and autophagic vesicle formation. | WGS project CABT00000000 data, contig 2.1. | 0.902 |