(85 nodes) Mixed, incl. Vesicle tethering complex, and Rab regulation of trafficking network (Sordaria macrospora)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	SMAC_12708	Putative GTP-binding protein ypt1. (203 aa)
	SMAC_00074	WGS project CABT00000000 data, contig 2.1. (829 aa)
	SMAC_00085	Probable vacuolar protein sorting-associated protein 16 homolog; Essential for vacuolar protein sorting. Required for vacuole biogenesis, stability and to maintain vacuole morphology. (859 aa)
	SMAC_00179	WGS project CABT00000000 data, contig 2.1. (740 aa)
	SMAC_00388	WGS project CABT00000000 data, contig 2.1. (696 aa)
	SMAC_00408	WGS project CABT00000000 data, contig 2.1. (863 aa)
	SMAC_00477	WGS project CABT00000000 data, contig 2.1. (437 aa)
	SMAC_00482	WGS project CABT00000000 data, contig 2.1. (903 aa)
	SMAC_04876	WGS project CABT00000000 data, contig 2.1. (411 aa)
	SMAC_07391	WGS project CABT00000000 data, contig 2.1. (465 aa)
	SMAC_00690	WGS project CABT00000000 data, contig 2.2. (1508 aa)
	SMAC_00836	WGS project CABT00000000 data, contig 2.2. (755 aa)
	SMAC_00854	Exocyst complex component SEC5; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. Belongs to the SEC5 family. (1126 aa)
	SMAC_00908	WGS project CABT00000000 data, contig 2.2; Belongs to the STXBP/unc-18/SEC1 family. (702 aa)
	SMAC_00945	WGS project CABT00000000 data, contig 2.2. (305 aa)
	SMAC_00950	WGS project CABT00000000 data, contig 2.2. (205 aa)
	SMAC_00951	WGS project CABT00000000 data, contig 2.2. (674 aa)
	SMAC_00979	WGS project CABT00000000 data, contig 2.2; Belongs to the synaptobrevin family. (242 aa)
	SMAC_01080	WGS project CABT00000000 data, contig 2.2. (1201 aa)
	SMAC_02300	WGS project CABT00000000 data, contig 2.3. (1154 aa)
	SMAC_02326	WGS project CABT00000000 data, contig 2.3. (426 aa)
	SMAC_02329	WGS project CABT00000000 data, contig 2.3. (292 aa)
	SMAC_02376	WGS project CABT00000000 data, contig 2.3. (287 aa)
	SMAC_02499	WGS project CABT00000000 data, contig 2.3. (1213 aa)
	SMAC_06764	WGS project CABT00000000 data, contig 2.3. (1079 aa)
	SMAC_01257	WGS project CABT00000000 data, contig 2.4. (117 aa)
	SMAC_01437	WGS project CABT00000000 data, contig 2.4. (432 aa)
	SMAC_01486	WGS project CABT00000000 data, contig 2.4. (158 aa)
	SMAC_01575	WGS project CABT00000000 data, contig 2.4. (366 aa)
	SMAC_01582	WGS project CABT00000000 data, contig 2.4. (220 aa)
	SMAC_01685	WGS project CABT00000000 data, contig 2.5. (489 aa)
	SMAC_01701	Rab GDP dissociation inhibitor; Belongs to the Rab GDI family. (443 aa)
	SMAC_01715	WGS project CABT00000000 data, contig 2.5. (669 aa)
	SMAC_01716	WGS project CABT00000000 data, contig 2.5. (375 aa)
	SMAC_01850	Exocyst complex protein EXO70; Involved in the secretory pathway as part of the exocyst complex which tethers secretory vesicles to the sites of exocytosis. Also plays a role in the assembly of the exocyst. Belongs to the EXO70 family. (667 aa)
	SMAC_01943	WGS project CABT00000000 data, contig 2.5; Belongs to the small GTPase superfamily. Arf family. (183 aa)
	SMAC_06807	WGS project CABT00000000 data, contig 2.6. (223 aa)
	SMAC_06806	WGS project CABT00000000 data, contig 2.6. (374 aa)
	SMAC_05807	WGS project CABT00000000 data, contig 2.6. (1672 aa)
	SMAC_07542	WGS project CABT00000000 data, contig 2.7. (251 aa)
	SMAC_03240	WGS project CABT00000000 data, contig 2.7. (1156 aa)
	SMAC_03156	WGS project CABT00000000 data, contig 2.7. (555 aa)
	SMAC_08311	Conserved oligomeric Golgi complex subunit 6; Acts as component of the peripheral membrane COG complex that is involved in intra-Golgi protein trafficking. COG is located at the cis-Golgi, and regulates tethering of retrograde intra-Golgi vesicles and possibly a number of other membrane trafficking events. (714 aa)
	SMAC_03707	WGS project CABT00000000 data, contig 2.9. (826 aa)
	SMAC_02533	WGS project CABT00000000 data, contig 2.11. (1063 aa)
	SMAC_02536	WGS project CABT00000000 data, contig 2.11. (861 aa)
	SMAC_02569	WGS project CABT00000000 data, contig 2.11. (205 aa)
	SMAC_02777	WGS project CABT00000000 data, contig 2.12. (877 aa)
	SMAC_06654	WGS project CABT00000000 data, contig 2.13. (603 aa)
	SMAC_06692	WGS project CABT00000000 data, contig 2.13. (937 aa)
	SMAC_06485	WGS project CABT00000000 data, contig 2.13. (213 aa)
	SMAC_04467	WGS project CABT00000000 data, contig 2.14; Belongs to the syntaxin family. (362 aa)
	SMAC_04462	WGS project CABT00000000 data, contig 2.14. (1272 aa)
	SMAC_04433	WGS project CABT00000000 data, contig 2.14. (380 aa)
	SMAC_04404	WGS project CABT00000000 data, contig 2.14. (1110 aa)
	SMAC_07820	WGS project CABT00000000 data, contig 2.14. (605 aa)
	SMAC_07823	WGS project CABT00000000 data, contig 2.14. (434 aa)
	SMAC_04092	WGS project CABT00000000 data, contig 2.15. (742 aa)
	SMAC_04158	E3 ubiquitin-protein ligase PEP5. (1017 aa)
	SMAC_02172	WGS project CABT00000000 data, contig 2.18. (236 aa)
	SMAC_04263	WGS project CABT00000000 data, contig 2.19. (1092 aa)
	SMAC_04568	WGS project CABT00000000 data, contig 2.20. (899 aa)
	SMAC_04617	WGS project CABT00000000 data, contig 2.20; Belongs to the STXBP/unc-18/SEC1 family. (666 aa)
	SMAC_04757	WGS project CABT00000000 data, contig 2.21. (681 aa)
	SMAC_05068	WGS project CABT00000000 data, contig 2.22. (178 aa)
	SMAC_05128	WGS project CABT00000000 data, contig 2.22. (404 aa)
	SMAC_02200	WGS project CABT00000000 data, contig 2.23. (772 aa)
	SMAC_05340	WGS project CABT00000000 data, contig 2.25. (420 aa)
	SMAC_05357	WGS project CABT00000000 data, contig 2.25. (973 aa)
	SMAC_05365	WGS project CABT00000000 data, contig 2.25; Belongs to the STXBP/unc-18/SEC1 family. (589 aa)
	SMAC_07579	WGS project CABT00000000 data, contig 2.27. (465 aa)
	SMAC_06514	WGS project CABT00000000 data, contig 2.28. (737 aa)
	SMAC_06515	WGS project CABT00000000 data, contig 2.28. (338 aa)
	SMAC_06027	WGS project CABT00000000 data, contig 2.32. (184 aa)
	SMAC_06430	WGS project CABT00000000 data, contig 2.35. (344 aa)
	SMAC_07021	WGS project CABT00000000 data, contig 2.36. (209 aa)
	SMAC_07167	WGS project CABT00000000 data, contig 2.40. (232 aa)
	SMAC_07290	WGS project CABT00000000 data, contig 2.44. (777 aa)
	SMAC_07507	WGS project CABT00000000 data, contig 2.46. (1332 aa)
	SMAC_08041	WGS project CABT00000000 data, contig 2.50. (548 aa)
	SMAC_08042	Geranylgeranyl transferase type-2 subunit beta; Catalyzes the transfer of a geranylgeranyl moiety from geranylgeranyl diphosphate to both cysteines of proteins with the C- terminal sequence -XXCC, -XCXC and -CCXX. (328 aa)
	SMAC_08083	Exocyst complex component SEC15; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. (791 aa)
	SMAC_08603	WGS project CABT00000000 data, contig 2.60. (999 aa)
	SMAC_09048	WGS project CABT00000000 data, contig 2.62. (1781 aa)
	SMAC_08734	WGS project CABT00000000 data, contig 2.64. (255 aa)

Your Current Organism:

Sordaria macrospora

NCBI taxonomy Id: 771870
Other names: S. macrospora k-hell, Sordaria macrospora k-hell

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structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
SMAC_00074	SMAC_00388	F7VK31	F7VKZ3	WGS project CABT00000000 data, contig 2.1.	WGS project CABT00000000 data, contig 2.1.	0.410
SMAC_00074	SMAC_01716	F7VK31	F7VRN2	WGS project CABT00000000 data, contig 2.1.	WGS project CABT00000000 data, contig 2.5.	0.516
SMAC_00074	SMAC_02536	F7VK31	F7VWR5	WGS project CABT00000000 data, contig 2.1.	WGS project CABT00000000 data, contig 2.11.	0.541
SMAC_00074	SMAC_07167	F7VK31	F7W7Q0	WGS project CABT00000000 data, contig 2.1.	WGS project CABT00000000 data, contig 2.40.	0.659
SMAC_00074	SMAC_07820	F7VK31	F7VZ56	WGS project CABT00000000 data, contig 2.1.	WGS project CABT00000000 data, contig 2.14.	0.557
SMAC_00074	SMAC_12708	F7VK31	F7VJW3	WGS project CABT00000000 data, contig 2.1.	Putative GTP-binding protein ypt1.	0.422
SMAC_00085	SMAC_00950	F7VK42	F7VNJ7	Probable vacuolar protein sorting-associated protein 16 homolog; Essential for vacuolar protein sorting. Required for vacuole biogenesis, stability and to maintain vacuole morphology.	WGS project CABT00000000 data, contig 2.2.	0.460
SMAC_00085	SMAC_00951	F7VK42	F7VNJ8	Probable vacuolar protein sorting-associated protein 16 homolog; Essential for vacuolar protein sorting. Required for vacuole biogenesis, stability and to maintain vacuole morphology.	WGS project CABT00000000 data, contig 2.2.	0.460
SMAC_00085	SMAC_00979	F7VK42	F7VNM6	Probable vacuolar protein sorting-associated protein 16 homolog; Essential for vacuolar protein sorting. Required for vacuole biogenesis, stability and to maintain vacuole morphology.	WGS project CABT00000000 data, contig 2.2; Belongs to the synaptobrevin family.	0.766
SMAC_00085	SMAC_01257	F7VK42	F7VQA8	Probable vacuolar protein sorting-associated protein 16 homolog; Essential for vacuolar protein sorting. Required for vacuole biogenesis, stability and to maintain vacuole morphology.	WGS project CABT00000000 data, contig 2.4.	0.527
SMAC_00085	SMAC_02172	F7VK42	F7W162	Probable vacuolar protein sorting-associated protein 16 homolog; Essential for vacuolar protein sorting. Required for vacuole biogenesis, stability and to maintain vacuole morphology.	WGS project CABT00000000 data, contig 2.18.	0.495
SMAC_00085	SMAC_02300	F7VK42	F7VP62	Probable vacuolar protein sorting-associated protein 16 homolog; Essential for vacuolar protein sorting. Required for vacuole biogenesis, stability and to maintain vacuole morphology.	WGS project CABT00000000 data, contig 2.3.	0.875
SMAC_00085	SMAC_02329	F7VK42	F7VP92	Probable vacuolar protein sorting-associated protein 16 homolog; Essential for vacuolar protein sorting. Required for vacuole biogenesis, stability and to maintain vacuole morphology.	WGS project CABT00000000 data, contig 2.3.	0.506
SMAC_00085	SMAC_02569	F7VK42	F7VWU8	Probable vacuolar protein sorting-associated protein 16 homolog; Essential for vacuolar protein sorting. Required for vacuole biogenesis, stability and to maintain vacuole morphology.	WGS project CABT00000000 data, contig 2.11.	0.790
SMAC_00085	SMAC_04158	F7VK42	F7VZI1	Probable vacuolar protein sorting-associated protein 16 homolog; Essential for vacuolar protein sorting. Required for vacuole biogenesis, stability and to maintain vacuole morphology.	E3 ubiquitin-protein ligase PEP5.	0.842
SMAC_00085	SMAC_04462	F7VK42	F7VYV3	Probable vacuolar protein sorting-associated protein 16 homolog; Essential for vacuolar protein sorting. Required for vacuole biogenesis, stability and to maintain vacuole morphology.	WGS project CABT00000000 data, contig 2.14.	0.838
SMAC_00085	SMAC_04617	F7VK42	F7W1Z8	Probable vacuolar protein sorting-associated protein 16 homolog; Essential for vacuolar protein sorting. Required for vacuole biogenesis, stability and to maintain vacuole morphology.	WGS project CABT00000000 data, contig 2.20; Belongs to the STXBP/unc-18/SEC1 family.	0.943
SMAC_00085	SMAC_05357	F7VK42	F7W3M9	Probable vacuolar protein sorting-associated protein 16 homolog; Essential for vacuolar protein sorting. Required for vacuole biogenesis, stability and to maintain vacuole morphology.	WGS project CABT00000000 data, contig 2.25.	0.865
SMAC_00085	SMAC_05365	F7VK42	F7W3N7	Probable vacuolar protein sorting-associated protein 16 homolog; Essential for vacuolar protein sorting. Required for vacuole biogenesis, stability and to maintain vacuole morphology.	WGS project CABT00000000 data, contig 2.25; Belongs to the STXBP/unc-18/SEC1 family.	0.521
SMAC_00085	SMAC_05807	F7VK42	F7VTA7	Probable vacuolar protein sorting-associated protein 16 homolog; Essential for vacuolar protein sorting. Required for vacuole biogenesis, stability and to maintain vacuole morphology.	WGS project CABT00000000 data, contig 2.6.	0.763