STRINGSTRING
SMAC_00470 SMAC_00470 SMAC_01050 SMAC_01050 ADK1 ADK1 SMAC_04987 SMAC_04987 SMAC_02848 SMAC_02848 ADK2 ADK2 SMAC_06675 SMAC_06675 SMAC_08849 SMAC_08849 SMAC_04510 SMAC_04510 SMAC_04509 SMAC_04509 SMAC_04392 SMAC_04392 SMAC_03806 SMAC_03806 SMAC_02161 SMAC_02161 SMAC_07771 SMAC_07771 SMAC_09163 SMAC_09163
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SMAC_00470WGS project CABT00000000 data, contig 2.1. (1023 aa)
SMAC_01050WGS project CABT00000000 data, contig 2.2. (194 aa)
ADK1Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways. (278 aa)
SMAC_04987WGS project CABT00000000 data, contig 2.8. (226 aa)
SMAC_02848Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. (536 aa)
ADK2GTP:AMP phosphotransferase, mitochondrial; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Has GTP:AMP phosphotransferase and ITP:AMP phosphotransferase activities. (273 aa)
SMAC_06675CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. (579 aa)
SMAC_08849WGS project CABT00000000 data, contig 2.13. (348 aa)
SMAC_04510Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. (192 aa)
SMAC_04509Adenylate kinase isoenzyme 6 homolog; Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. Has also ATPase activity. May be involved in rRNA maturation and transcription regulation. (175 aa)
SMAC_04392Nucleoside diphosphate kinase. (152 aa)
SMAC_03806WGS project CABT00000000 data, contig 2.16; Belongs to the GDA1/CD39 NTPase family. (750 aa)
SMAC_02161WGS project CABT00000000 data, contig 2.18. (410 aa)
SMAC_07771Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. (937 aa)
SMAC_09163WGS project CABT00000000 data, contig 2.74. (520 aa)
Your Current Organism:
Sordaria macrospora
NCBI taxonomy Id: 771870
Other names: S. macrospora k-hell, Sordaria macrospora k-hell
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