(5 nodes) GMP metabolic process, and AMP salvage network (Sordaria macrospora)

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Your Input:
	SMAC_01050	WGS project CABT00000000 data, contig 2.2. (194 aa)
	SMAC_04987	WGS project CABT00000000 data, contig 2.8. (226 aa)
	SMAC_02848	Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. (536 aa)
	SMAC_04510	Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. (192 aa)
	SMAC_09163	WGS project CABT00000000 data, contig 2.74. (520 aa)

Your Current Organism:

Sordaria macrospora

NCBI taxonomy Id: 771870
Other names: S. macrospora k-hell, Sordaria macrospora k-hell

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
SMAC_01050	SMAC_02848	F7VNU8	F7VXM7	WGS project CABT00000000 data, contig 2.2.	Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.	0.446
SMAC_01050	SMAC_04510	F7VNU8	F7VYQ6	WGS project CABT00000000 data, contig 2.2.	Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.	0.941
SMAC_01050	SMAC_04987	F7VNU8	F7VUN2	WGS project CABT00000000 data, contig 2.2.	WGS project CABT00000000 data, contig 2.8.	0.975
SMAC_01050	SMAC_09163	F7VNU8	F7WBE1	WGS project CABT00000000 data, contig 2.2.	WGS project CABT00000000 data, contig 2.74.	0.974
SMAC_02848	SMAC_01050	F7VXM7	F7VNU8	Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.	WGS project CABT00000000 data, contig 2.2.	0.446
SMAC_02848	SMAC_04510	F7VXM7	F7VYQ6	Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.	Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.	0.966
SMAC_02848	SMAC_04987	F7VXM7	F7VUN2	Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.	WGS project CABT00000000 data, contig 2.8.	0.705
SMAC_02848	SMAC_09163	F7VXM7	F7WBE1	Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.	WGS project CABT00000000 data, contig 2.74.	0.999
SMAC_04510	SMAC_01050	F7VYQ6	F7VNU8	Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.	WGS project CABT00000000 data, contig 2.2.	0.941
SMAC_04510	SMAC_02848	F7VYQ6	F7VXM7	Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.	Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.	0.966
SMAC_04510	SMAC_04987	F7VYQ6	F7VUN2	Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.	WGS project CABT00000000 data, contig 2.8.	0.983
SMAC_04510	SMAC_09163	F7VYQ6	F7WBE1	Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.	WGS project CABT00000000 data, contig 2.74.	0.962
SMAC_04987	SMAC_01050	F7VUN2	F7VNU8	WGS project CABT00000000 data, contig 2.8.	WGS project CABT00000000 data, contig 2.2.	0.975
SMAC_04987	SMAC_02848	F7VUN2	F7VXM7	WGS project CABT00000000 data, contig 2.8.	Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.	0.705
SMAC_04987	SMAC_04510	F7VUN2	F7VYQ6	WGS project CABT00000000 data, contig 2.8.	Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.	0.983
SMAC_04987	SMAC_09163	F7VUN2	F7WBE1	WGS project CABT00000000 data, contig 2.8.	WGS project CABT00000000 data, contig 2.74.	0.988
SMAC_09163	SMAC_01050	F7WBE1	F7VNU8	WGS project CABT00000000 data, contig 2.74.	WGS project CABT00000000 data, contig 2.2.	0.974
SMAC_09163	SMAC_02848	F7WBE1	F7VXM7	WGS project CABT00000000 data, contig 2.74.	Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.	0.999
SMAC_09163	SMAC_04510	F7WBE1	F7VYQ6	WGS project CABT00000000 data, contig 2.74.	Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.	0.962
SMAC_09163	SMAC_04987	F7WBE1	F7VUN2	WGS project CABT00000000 data, contig 2.74.	WGS project CABT00000000 data, contig 2.8.	0.988