STRINGSTRING
SMAC_02366 SMAC_02366 SMAC_03990 SMAC_03990 MDE1 MDE1 UTR4 UTR4 SMAC_00024 SMAC_00024 SMAC_00145 SMAC_00145 SMAC_00221 SMAC_00221 SMAC_00496 SMAC_00496 SMAC_00511 SMAC_00511 SMAC_00545 SMAC_00545 SMAC_04834 SMAC_04834 SMAC_04891 SMAC_04891 SMAC_07383 SMAC_07383 SMAC_01203 SMAC_01203 SMAC_00637 SMAC_00637 SMAC_00737 SMAC_00737 SMAC_00763 SMAC_00763 SMAC_00837 SMAC_00837 SMAC_00862 SMAC_00862 SMAC_00870 SMAC_00870 SMAC_00930 SMAC_00930 SMAC_00990 SMAC_00990 SMAC_01029 SMAC_01029 SMAC_01030 SMAC_01030 SMAC_02388 SMAC_02388 SMAC_02389 SMAC_02389 SMAC_02431 SMAC_02431 SMAC_02504 SMAC_02504 SMAC_08139 SMAC_08139 SMAC_01230 SMAC_01230 SMAC_01246 SMAC_01246 SMAC_01258 SMAC_01258 SMAC_01272 SMAC_01272 SMAC_01464 SMAC_01464 SMAC_01479 SMAC_01479 SMAC_01573 SMAC_01573 SMAC_01628 SMAC_01628 SMAC_01760 SMAC_01760 SMAC_01814 SMAC_01814 SMAC_01824 SMAC_01824 SMAC_01902 SMAC_01902 MET3 MET3 SMAC_05447 SMAC_05447 SMAC_05448 SMAC_05448 SMAC_05453 SMAC_05453 SMAC_05724 SMAC_05724 SMAC_05796 SMAC_05796 SMAC_07530 SMAC_07530 SMAC_07546 SMAC_07546 SMAC_03146 SMAC_03146 SMAC_03112 SMAC_03112 SMAC_03111 SMAC_03111 SMAC_04991 SMAC_04991 SMAC_05254 SMAC_05254 SMAC_08318 SMAC_08318 SMAC_03590 SMAC_03590 SMAC_03713 SMAC_03713 SMAC_03391 SMAC_03391 SMAC_03452 SMAC_03452 SMAC_03269 SMAC_03269 SMAC_02559 SMAC_02559 SMAC_02595 SMAC_02595 SMAC_02605 SMAC_02605 SMAC_02748 SMAC_02748 SMAC_02770 SMAC_02770 SMAC_02849 SMAC_02849 SMAC_02870 SMAC_02870 SMAC_12089 SMAC_12089 SMAC_04494 SMAC_04494 SMAC_04468 SMAC_04468 SMAC_07850 SMAC_07850 SMAC_04149 SMAC_04149 SMAC_04156 SMAC_04156 SMAC_03729 SMAC_03729 SMAC_03869 SMAC_03869 SMAC_03994 SMAC_03994 SMAC_02039 SMAC_02039 SMAC_02086 SMAC_02086 SMAC_04331 SMAC_04331 SMAC_04612 SMAC_04612 SMAC_04671 SMAC_04671 SMAC_04788 SMAC_04788 SMAC_04794 SMAC_04794 SMAC_05116 SMAC_05116 SMAC_02214 SMAC_02214 SMAC_02229 SMAC_02229 SMAC_02234 SMAC_02234 SMAC_02273 SMAC_02273 ADI1 ADI1 SMAC_05345 SMAC_05345 SMAC_05583 SMAC_05583 SMAC_05588 SMAC_05588 SMAC_05595 SMAC_05595 SMAC_09398 SMAC_09398 SMAC_08386 SMAC_08386 SMAC_07643 SMAC_07643 SMAC_06021 SMAC_06021 SMAC_06023 SMAC_06023 SMAC_06132 SMAC_06132 SMAC_06351 SMAC_06351 SMAC_06403 SMAC_06403 SMAC_06582 SMAC_06582 SMAC_06609 SMAC_06609 SMAC_06619 SMAC_06619 SMAC_06935 SMAC_06935 SMAC_07082 SMAC_07082 SMAC_07315 SMAC_07315 SMAC_07336 SMAC_07336 SMAC_07740 SMAC_07740 SMAC_07741 SMAC_07741 SMAC_08048 SMAC_08048 SMAC_08095 SMAC_08095 SMAC_08456 SMAC_08456 SMAC_08477 SMAC_08477 SMAC_09041 SMAC_09041 SMAC_08688 SMAC_08688 SMAC_08873 SMAC_08873 SMAC_08891 SMAC_08891 SMAC_09602 SMAC_09602 SMAC_09686 SMAC_09686 SMAC_09665 SMAC_09665 SMAC_09909 SMAC_09909 SMAC_10080 SMAC_10080 SMAC_11153 SMAC_11153 MRI1 MRI1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SMAC_023663-phosphoshikimate 1-carboxyvinyltransferase; The AROM polypeptide catalyzes 5 consecutive enzymatic reactions in prechorismate polyaromatic amino acid biosynthesis. In the N-terminal section; belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family. In the 3rd section; belongs to the shikimate kinase family. In the C-terminal section; belongs to the shikimate dehydrogenase family. (1563 aa)
SMAC_03990Arginine biosynthesis bifunctional protein ArgJ, mitochondrial; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of acetylglutamate from glutamate and acetyl-CoA, and of ornithine by transacetylation between acetylornithine and glutamate. (469 aa)
MDE1Methylthioribulose-1-phosphate dehydratase; Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P). (273 aa)
UTR4Enolase-phosphatase E1; Bifunctional enzyme that catalyzes the enolization of 2,3- diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK- MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene). (234 aa)
SMAC_00024WGS project CABT00000000 data, contig 2.1. (401 aa)
SMAC_00145WGS project CABT00000000 data, contig 2.1; Belongs to the dihydrofolate reductase family. (223 aa)
SMAC_00221WGS project CABT00000000 data, contig 2.1. (385 aa)
SMAC_00496WGS project CABT00000000 data, contig 2.1. (357 aa)
SMAC_00511WGS project CABT00000000 data, contig 2.1. (203 aa)
SMAC_00545WGS project CABT00000000 data, contig 2.1. (528 aa)
SMAC_04834Phospho-2-dehydro-3-deoxyheptonate aldolase; Belongs to the class-II DAHP synthase family. (478 aa)
SMAC_04891WGS project CABT00000000 data, contig 2.1. (417 aa)
SMAC_07383Threonine dehydratase. (523 aa)
SMAC_01203Aspartate aminotransferase. (483 aa)
SMAC_00637WGS project CABT00000000 data, contig 2.2. (260 aa)
SMAC_00737WGS project CABT00000000 data, contig 2.2. (405 aa)
SMAC_00763Histidinol-phosphatase; Belongs to the PHP hydrolase family. HisK subfamily. (316 aa)
SMAC_00837WGS project CABT00000000 data, contig 2.2. (611 aa)
SMAC_00862Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. (568 aa)
SMAC_00870Amino-acid acetyltransferase, mitochondrial; N-acetylglutamate synthase involved in arginine biosynthesis. Belongs to the acetyltransferase family. (692 aa)
SMAC_00930WGS project CABT00000000 data, contig 2.2. (1832 aa)
SMAC_00990WGS project CABT00000000 data, contig 2.2. (403 aa)
SMAC_01029WGS project CABT00000000 data, contig 2.2. (282 aa)
SMAC_01030WGS project CABT00000000 data, contig 2.2. (667 aa)
SMAC_02388WGS project CABT00000000 data, contig 2.3. (318 aa)
SMAC_02389WGS project CABT00000000 data, contig 2.3; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. (363 aa)
SMAC_02431WGS project CABT00000000 data, contig 2.3. (2116 aa)
SMAC_02504WGS project CABT00000000 data, contig 2.3. (447 aa)
SMAC_08139Tryptophan synthase. (708 aa)
SMAC_01230WGS project CABT00000000 data, contig 2.4. (524 aa)
SMAC_01246WGS project CABT00000000 data, contig 2.4. (362 aa)
SMAC_01258WGS project CABT00000000 data, contig 2.4; In the N-terminal section; belongs to the acetylglutamate kinase family. (871 aa)
SMAC_01272WGS project CABT00000000 data, contig 2.4. (339 aa)
SMAC_01464WGS project CABT00000000 data, contig 2.4; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (361 aa)
SMAC_01479WGS project CABT00000000 data, contig 2.4. (357 aa)
SMAC_01573WGS project CABT00000000 data, contig 2.4; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (382 aa)
SMAC_01628WGS project CABT00000000 data, contig 2.4. (573 aa)
SMAC_017603-isopropylmalate dehydratase; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (784 aa)
SMAC_01814Acetolactate synthase. (689 aa)
SMAC_01824WGS project CABT00000000 data, contig 2.5. (448 aa)
SMAC_01902Prephenate dehydrogenase [NADP(+)]; Belongs to the prephenate/arogenate dehydrogenase family. (445 aa)
MET3Sulfate adenylyltransferase; Catalyzes the first intracellular reaction of sulfate assimilation, forming adenosine-5'-phosphosulfate (APS) from inorganic sulfate and ATP. Plays an important role in sulfate activation as a component of the biosynthesis pathway of sulfur-containing amino acids. In the N-terminal section; belongs to the sulfate adenylyltransferase family. (573 aa)
SMAC_05447WGS project CABT00000000 data, contig 2.6. (496 aa)
SMAC_05448WGS project CABT00000000 data, contig 2.6. (315 aa)
SMAC_05453WGS project CABT00000000 data, contig 2.6. (621 aa)
SMAC_05724WGS project CABT00000000 data, contig 2.6. (417 aa)
SMAC_05796WGS project CABT00000000 data, contig 2.6. (421 aa)
SMAC_07530WGS project CABT00000000 data, contig 2.7. (797 aa)
SMAC_07546Glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (454 aa)
SMAC_03146WGS project CABT00000000 data, contig 2.7. (393 aa)
SMAC_03112WGS project CABT00000000 data, contig 2.7. (383 aa)
SMAC_03111Ketol-acid reductoisomerase, mitochondrial; Belongs to the ketol-acid reductoisomerase family. (401 aa)
SMAC_04991WGS project CABT00000000 data, contig 2.8. (240 aa)
SMAC_05254WGS project CABT00000000 data, contig 2.8. (802 aa)
SMAC_08318WGS project CABT00000000 data, contig 2.9. (689 aa)
SMAC_03590WGS project CABT00000000 data, contig 2.9. (466 aa)
SMAC_03713Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (480 aa)
SMAC_03391Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (405 aa)
SMAC_03452D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (652 aa)
SMAC_03269Phospho-2-dehydro-3-deoxyheptonate aldolase. (379 aa)
SMAC_02559WGS project CABT00000000 data, contig 2.11. (620 aa)
SMAC_02595WGS project CABT00000000 data, contig 2.11. (418 aa)
SMAC_02605WGS project CABT00000000 data, contig 2.11. (700 aa)
SMAC_02748WGS project CABT00000000 data, contig 2.11. (385 aa)
SMAC_02770WGS project CABT00000000 data, contig 2.12. (345 aa)
SMAC_02849Saccharopine dehydrogenase [NAD(+), L-lysine-forming]; Belongs to the AlaDH/PNT family. (372 aa)
SMAC_02870Histidine biosynthesis trifunctional protein. (870 aa)
SMAC_12089WGS project CABT00000000 data, contig 2.13. (366 aa)
SMAC_04494WGS project CABT00000000 data, contig 2.14. (549 aa)
SMAC_04468Aspartokinase. (523 aa)
SMAC_07850WGS project CABT00000000 data, contig 2.14. (359 aa)
SMAC_04149WGS project CABT00000000 data, contig 2.15; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (377 aa)
SMAC_04156Chorismate synthase. (432 aa)
SMAC_03729WGS project CABT00000000 data, contig 2.16. (330 aa)
SMAC_03869WGS project CABT00000000 data, contig 2.16. (641 aa)
SMAC_03994Imidazoleglycerol-phosphate dehydratase; Belongs to the imidazoleglycerol-phosphate dehydratase family. (229 aa)
SMAC_02039WGS project CABT00000000 data, contig 2.18. (629 aa)
SMAC_02086WGS project CABT00000000 data, contig 2.18. (229 aa)
SMAC_04331WGS project CABT00000000 data, contig 2.19. (1147 aa)
SMAC_04612WGS project CABT00000000 data, contig 2.20. (558 aa)
SMAC_04671WGS project CABT00000000 data, contig 2.21; Belongs to the PdxS/SNZ family. (305 aa)
SMAC_04788WGS project CABT00000000 data, contig 2.21. (453 aa)
SMAC_04794Chorismate mutase. (269 aa)
SMAC_05116Homoaconitase, mitochondrial; Catalyzes the reversible hydration of cis-homoaconitate to (2R,3S)-homoisocitrate, a step in the alpha-aminoadipate pathway for lysine biosynthesis. (733 aa)
SMAC_02214WGS project CABT00000000 data, contig 2.23. (376 aa)
SMAC_02229WGS project CABT00000000 data, contig 2.23. (743 aa)
SMAC_02234Ornithine aminotransferase. (410 aa)
SMAC_022731-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase. (257 aa)
ADI11,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase; Catalyzes the formation of formate and 2-keto-4- methylthiobutyrate (KMTB) from 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene). (157 aa)
SMAC_05345WGS project CABT00000000 data, contig 2.25. (769 aa)
SMAC_05583WGS project CABT00000000 data, contig 2.26. (581 aa)
SMAC_05588WGS project CABT00000000 data, contig 2.26. (760 aa)
SMAC_05595Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (431 aa)
SMAC_09398WGS project CABT00000000 data, contig 2.27. (582 aa)
SMAC_08386WGS project CABT00000000 data, contig 2.28. (446 aa)
SMAC_07643Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (550 aa)
SMAC_06021WGS project CABT00000000 data, contig 2.32. (819 aa)
SMAC_06023WGS project CABT00000000 data, contig 2.32. (385 aa)
SMAC_06132S-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates. (310 aa)
SMAC_06351Homoserine dehydrogenase. (348 aa)
SMAC_06403WGS project CABT00000000 data, contig 2.35. (570 aa)
SMAC_06582Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. (772 aa)
SMAC_06609Glutamine synthetase. (362 aa)
SMAC_06619WGS project CABT00000000 data, contig 2.37. (972 aa)
SMAC_06935Imidazole glycerol phosphate synthase hisHF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The glutaminase domain produces the ammonia necessary for the cyclase domain to produce IGP and AICAR from PRFAR. The ammonia is channeled to the active site of the cyclase domain. Belongs to the HisA/HisF family. (551 aa)
SMAC_070823-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. (368 aa)
SMAC_07315WGS project CABT00000000 data, contig 2.44; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (495 aa)
SMAC_07336WGS project CABT00000000 data, contig 2.45. (436 aa)
SMAC_07740WGS project CABT00000000 data, contig 2.47. (165 aa)
SMAC_07741WGS project CABT00000000 data, contig 2.47. (457 aa)
SMAC_08048WGS project CABT00000000 data, contig 2.50. (630 aa)
SMAC_08095WGS project CABT00000000 data, contig 2.52. (458 aa)
SMAC_08456WGS project CABT00000000 data, contig 2.58. (413 aa)
SMAC_08477Phospho-2-dehydro-3-deoxyheptonate aldolase. (373 aa)
SMAC_09041Glutamine synthetase. (368 aa)
SMAC_08688WGS project CABT00000000 data, contig 2.63. (582 aa)
SMAC_08873WGS project CABT00000000 data, contig 2.67. (554 aa)
SMAC_08891Pyrroline-5-carboxylate reductase; Belongs to the pyrroline-5-carboxylate reductase family. (331 aa)
SMAC_09602Cystathionine beta-synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. (527 aa)
SMAC_09686WGS project CABT00000000 data, contig 2.116. (525 aa)
SMAC_09665WGS project CABT00000000 data, contig 2.142. (370 aa)
SMAC_09909WGS project CABT00000000 data, contig 2.266. (70 aa)
SMAC_10080WGS project CABT00000000 data, contig 2.323. (301 aa)
SMAC_11153WGS project CABT00000000 data, contig 2.628. (106 aa)
MRI1Methylthioribose-1-phosphate isomerase; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily. (388 aa)
Your Current Organism:
Sordaria macrospora
NCBI taxonomy Id: 771870
Other names: S. macrospora k-hell, Sordaria macrospora k-hell
Server load: low (34%) [HD]