69 items (Sordaria macrospora) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	SMAC_00712	WGS project CABT00000000 data, contig 2.2. (470 aa)
	SMAC_10120	4-hydroxyphenylpyruvate dioxygenase. (352 aa)
	SMAC_10080	WGS project CABT00000000 data, contig 2.323. (301 aa)
	SMAC_08948	WGS project CABT00000000 data, contig 2.70. (536 aa)
	BNA5-2	Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively; Belongs to the kynureninase family. (482 aa)
	SMAC_08869	WGS project CABT00000000 data, contig 2.67; Belongs to the aldehyde dehydrogenase family. (474 aa)
	SMAC_08628	WGS project CABT00000000 data, contig 2.61. (344 aa)
	SMAC_07976	Glycine cleavage system H protein; The H protein shuttles the methylamine group of glycine from the P protein to the T protein; Belongs to the GcvH family. (169 aa)
	SMAC_07315	WGS project CABT00000000 data, contig 2.44; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (495 aa)
	SMAC_07270	WGS project CABT00000000 data, contig 2.44; Belongs to the aldehyde dehydrogenase family. (484 aa)
	SMAC_06335	WGS project CABT00000000 data, contig 2.34. (417 aa)
	SMAC_06326	WGS project CABT00000000 data, contig 2.34. (512 aa)
	SMAC_06144	WGS project CABT00000000 data, contig 2.33. (531 aa)
	SMAC_08990	WGS project CABT00000000 data, contig 2.31. (507 aa)
	SMAC_07643	Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (550 aa)
	SMAC_05655	WGS project CABT00000000 data, contig 2.30. (437 aa)
	SMAC_05651	WGS project CABT00000000 data, contig 2.30; Belongs to the PAL/histidase family. (765 aa)
	BNA4	Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid. (510 aa)
	SMAC_02234	Ornithine aminotransferase. (410 aa)
	SMAC_04752	Cysteine dioxygenase. (231 aa)
	SMAC_04681	3-hydroxyisobutyrate dehydrogenase; Belongs to the HIBADH-related family. (338 aa)
	SMAC_04361	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex. (555 aa)
	SMAC_04322	WGS project CABT00000000 data, contig 2.19. (517 aa)
	SMAC_04291	Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine; Belongs to the GcvT family. (466 aa)
	SMAC_12591	WGS project CABT00000000 data, contig 2.18; Belongs to the aldehyde dehydrogenase family. (375 aa)
	SMAC_12103	WGS project CABT00000000 data, contig 2.17. (182 aa)
	SMAC_03900	WGS project CABT00000000 data, contig 2.16; Belongs to the aldehyde dehydrogenase family. (479 aa)
	SMAC_03881	WGS project CABT00000000 data, contig 2.16. (452 aa)
	SMAC_04155	WGS project CABT00000000 data, contig 2.15. (407 aa)
	SMAC_04083	WGS project CABT00000000 data, contig 2.15. (486 aa)
	SMAC_06449	WGS project CABT00000000 data, contig 2.13; Belongs to the aldehyde dehydrogenase family. (495 aa)
	BNA1	3-hydroxyanthranilate 3,4-dioxygenase; Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate. (180 aa)
	SMAC_02805	Delta-1-pyrroline-5-carboxylate dehydrogenase; Belongs to the aldehyde dehydrogenase family. (607 aa)
	SMAC_02745	WGS project CABT00000000 data, contig 2.11. (695 aa)
	SMAC_02624	3-hydroxyisobutyryl-CoA hydrolase, mitochondrial; Hydrolyzes 3-hydroxyisobutyryl-CoA (HIBYL-CoA), a saline catabolite; Belongs to the enoyl-CoA hydratase/isomerase family. (468 aa)
	SMAC_02611	WGS project CABT00000000 data, contig 2.11. (376 aa)
	SMAC_03341	WGS project CABT00000000 data, contig 2.10. (489 aa)
	SMAC_03257	Fumarylacetoacetase. (403 aa)
	SMAC_03406	WGS project CABT00000000 data, contig 2.10. (508 aa)
	SMAC_03713	Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (480 aa)
	SMAC_03556	Arginase; Belongs to the arginase family. (364 aa)
	SMAC_08326	WGS project CABT00000000 data, contig 2.9. (417 aa)
	SMAC_05027	WGS project CABT00000000 data, contig 2.8. (473 aa)
	SMAC_05026	WGS project CABT00000000 data, contig 2.8. (613 aa)
	SMAC_04952	WGS project CABT00000000 data, contig 2.8. (476 aa)
	SMAC_03146	WGS project CABT00000000 data, contig 2.7. (393 aa)
	SMAC_05995	Glycine cleavage system P protein; The glycine cleavage system catalyzes the degradation of glycine. (1071 aa)
	SMAC_01953	WGS project CABT00000000 data, contig 2.5; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (516 aa)
	BNA5	Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively; Belongs to the kynureninase family. (495 aa)
	SMAC_01896	NAD-specific glutamate dehydrogenase; NAD(+)-dependent glutamate dehydrogenase which degrades glutamate to ammonia and alpha-ketoglutarate. Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (1050 aa)
	SMAC_01602	Cysteine proteinase 1, mitochondrial; Has aminopeptidase activity, shortening substrate peptides sequentially by 1 amino acid. Has bleomycin hydrolase activity, which can protect the cell from the toxic effects of bleomycin. Has homocysteine-thiolactonase activity, protecting the cell against homocysteine toxicity. (503 aa)
	SMAC_01528	WGS project CABT00000000 data, contig 2.4. (370 aa)
	SMAC_01357	Glutamate decarboxylase; Belongs to the group II decarboxylase family. (619 aa)
	SMAC_01322	WGS project CABT00000000 data, contig 2.4. (323 aa)
	SMAC_08142	Aspartate aminotransferase. (428 aa)
	SMAC_06785	Kynurenine formamidase; Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation. Kynurenine may be further oxidized to nicotinic acid, NAD(H) and NADP(H). Required for elimination of toxic metabolites. (415 aa)
	SMAC_12755	Glutamate decarboxylase; Belongs to the group II decarboxylase family. (617 aa)
	SMAC_02511	4-hydroxyphenylpyruvate dioxygenase. (413 aa)
	SMAC_01009	WGS project CABT00000000 data, contig 2.2. (320 aa)
	SMAC_01008	WGS project CABT00000000 data, contig 2.2. (207 aa)
	SMAC_00684	2-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3). (475 aa)
	SMAC_00655	WGS project CABT00000000 data, contig 2.2. (297 aa)
	SMAC_01196	WGS project CABT00000000 data, contig 2.2; Belongs to the PAL/histidase family. (635 aa)
	SMAC_07383	Threonine dehydratase. (523 aa)
	SMAC_04851	WGS project CABT00000000 data, contig 2.1. (586 aa)
	SMAC_00512	Proline dehydrogenase; Converts proline to delta-1-pyrroline-5-carboxylate. (444 aa)
	SMAC_00284	WGS project CABT00000000 data, contig 2.1. (438 aa)
	SMAC_00221	WGS project CABT00000000 data, contig 2.1. (385 aa)
	SMAC_00212	Succinate-semialdehyde dehydrogenase. (537 aa)

Your Current Organism:

Sordaria macrospora

NCBI taxonomy Id: 771870
Other names: S. macrospora k-hell, Sordaria macrospora k-hell

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BNA1	BNA4	F7VY31	F7W3C4	3-hydroxyanthranilate 3,4-dioxygenase; Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate.	Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid.	0.863
BNA1	BNA5	F7VY31	F7VS63	3-hydroxyanthranilate 3,4-dioxygenase; Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate.	Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively; Belongs to the kynureninase family.	0.980
BNA1	BNA5-2	F7VY31	F7WB68	3-hydroxyanthranilate 3,4-dioxygenase; Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate.	Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively; Belongs to the kynureninase family.	0.980
BNA1	SMAC_06785	F7VY31	F7VQ06	3-hydroxyanthranilate 3,4-dioxygenase; Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate.	Kynurenine formamidase; Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation. Kynurenine may be further oxidized to nicotinic acid, NAD(H) and NADP(H). Required for elimination of toxic metabolites.	0.412
BNA1	SMAC_08948	F7VY31	F7WB69	3-hydroxyanthranilate 3,4-dioxygenase; Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate.	WGS project CABT00000000 data, contig 2.70.	0.499
BNA1	SMAC_08990	F7VY31	F7W5S5	3-hydroxyanthranilate 3,4-dioxygenase; Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate.	WGS project CABT00000000 data, contig 2.31.	0.499
BNA4	BNA1	F7W3C4	F7VY31	Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid.	3-hydroxyanthranilate 3,4-dioxygenase; Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate.	0.863
BNA4	BNA5	F7W3C4	F7VS63	Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid.	Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively; Belongs to the kynureninase family.	0.987
BNA4	BNA5-2	F7W3C4	F7WB68	Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid.	Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively; Belongs to the kynureninase family.	0.986
BNA4	SMAC_00712	F7W3C4	F7VMV7	Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid.	WGS project CABT00000000 data, contig 2.2.	0.492
BNA4	SMAC_08948	F7W3C4	F7WB69	Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid.	WGS project CABT00000000 data, contig 2.70.	0.476
BNA4	SMAC_08990	F7W3C4	F7W5S5	Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid.	WGS project CABT00000000 data, contig 2.31.	0.476
BNA5	BNA1	F7VS63	F7VY31	Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively; Belongs to the kynureninase family.	3-hydroxyanthranilate 3,4-dioxygenase; Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate.	0.980
BNA5	BNA4	F7VS63	F7W3C4	Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively; Belongs to the kynureninase family.	Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid.	0.987
BNA5	BNA5-2	F7VS63	F7WB68	Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively; Belongs to the kynureninase family.	Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively; Belongs to the kynureninase family.	0.904
BNA5	SMAC_00712	F7VS63	F7VMV7	Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively; Belongs to the kynureninase family.	WGS project CABT00000000 data, contig 2.2.	0.569
BNA5	SMAC_03257	F7VS63	F7VWC9	Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively; Belongs to the kynureninase family.	Fumarylacetoacetase.	0.408
BNA5	SMAC_06144	F7VS63	F7W662	Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively; Belongs to the kynureninase family.	WGS project CABT00000000 data, contig 2.33.	0.418
BNA5	SMAC_06785	F7VS63	F7VQ06	Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively; Belongs to the kynureninase family.	Kynurenine formamidase; Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation. Kynurenine may be further oxidized to nicotinic acid, NAD(H) and NADP(H). Required for elimination of toxic metabolites.	0.460
BNA5	SMAC_08948	F7VS63	F7WB69	Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively; Belongs to the kynureninase family.	WGS project CABT00000000 data, contig 2.70.	0.930